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Seroquel User Reviews & Ratings (Page 3)

Seroquel has an average rating of 6.8 out of 10 from a total of 493 reviews on Drugs.com. 60% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Seroquel

  • Anonymous
  • April 21, 2012

For Borderline Personality Disorder "I have been suffering with borderline personality disorder almost my entire life. Within a few days of taking Seroquel, I noticed an incredible difference in my mood balance and my paranoia. The biggest difference I noticed was I no longer felt the need to be in crisis. Social settings were easily handled, and my work life improved overnight. I used to use alcohol to expand on my crisis moments, and friends and family believed me a hopeless alcoholic. Now I have no urge to drink. I wake up focused, ready, and able to face the day. Most of my days are almost completely positive. I would recommend."

9 / 10
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115 Report
  • Anonymous
  • April 13, 2012

For Generalized Anxiety Disorder "My doctor prescribed Seroquel for a number of psychiatric conditions I have. They are: Depression (already on 40 mg Celexa for this, Seroquel helped as an add-on), OCD, Generalized Anxiety Disorder, anorexia, and mood instability. Seroquel helps with all these conditions, although it causes moderate constipation."

8 / 10
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115 Report
  • Anonymous
  • November 26, 2010

For Generalized Anxiety Disorder "After trying nearly every SSRI on the market, I was placed on Pristiq, which improved my condition somewhat, but still left me dependent on Xanax to alleviate my daily anxiety. After a particularly bad stretch, I was also placed on Seroquel XR. It has helped more than I could have ever hoped for. I finally don't have to reach for Xanax as soon as I wake up. It was very sedating for the first week after I started and after increasing my dosage, but this has lessened with time. I do make sure to take it before bed, as it does make me tired as it kicks in, but I welcome this due to my problems with insomnia."

9 / 10
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124 Report

Frequently asked questions

  • Gemini
  • November 10, 2014

For Bipolar Disorder "Seroquel has worked wonders for me. I have been diagnosed with Bipolar 2, and after 7 months on Seroquel, I feel like a whole new person. I had been severely depressed and was self-harming before getting on Seroquel, and now I have never been so happy before! The only problem is the weight gain - I have gained about 20 pounds since I started taking this medicine. But this side effect is worth it to have my depression and anxiety gone!"

9 / 10
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95 Report
  • Ahimsa
  • March 30, 2019

For Bipolar Disorder "Warning: may trigger suicidal thoughts. History: I was prescribed Seroquel after multiple meds weren’t helping to improve my depression. Quickly, my depression got markedly worse to the point of me not being able to get out of bed and not bathing because they felt too exhausting. I also had my suicidal ideation and thoughts get overwhelmingly worse. My psychiatrist increased my dosage and it just got worse. I had to change psychiatrists (unrelated to this) and my new psychiatrist immediately had me taper down my dosage with the goal of getting off the Seroquel completely. Once I got off of it completely, I felt like a new person - no depression or suicidal thoughts since. I know this med has helped a lot of people and I am so happy it has. I don’t think many other people have had this experience, but wanted to put it out there that it wasn’t good for me and if anyone is having similar experiences, please speak with the person who prescribed it and know that it can get better."

1 / 10
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60 Report

Are you taking this medicine?

  • littl...
  • March 15, 2014

For Bipolar Disorder "Seroquel gave me my life back, calms me down and helps me think clearly during the day, and helps me sleep well during the night. Makes your mouth a bit dry and makes you hungry often but definitely worth it."

9 / 10
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98 Report
  • Wizar...
  • Taken for less than 1 month
  • May 13, 2016

For Bipolar Disorder "I was diagnosed with Bipolar II when I was 15 years old and have used only cannabis since then to deal with it, but after years of cannabis abuse, my symptoms started to become uncontrollable. I needed to smoke 2-3 grams of weed a day just to stay physically calm, and even then I had a lot of internal anxiety and no motivation. I could never quit smoking because if I did, I couldn't sleep, couldn't eat, couldn't sit still, and couldn't feel any joy. I would always relapse if I quit. I started Seroquel a week ago, and haven't had any weed since; I can eat normally, sleep 6-7 hours a night, and feel relatively happy. Plus, I have literally no side effects as far as I can tell. I haven't felt this good in years; It's all uphill from here!"

9 / 10
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  • Sandie...
  • October 19, 2008

For Obsessive Compulsive Disorder "I suffer from extreme anxiety and obsessive-compulsive disorder. I was prescribed Seroquel 25 mg (one in the morning and two at bedtime). This medication has done wonders for me in a very short period of time (one week). In low doses, Seroquel is effectively taking the edge off life, and I'm a much happier person. It's like a miracle drug for me, and I can't imagine going back to life without it."

10 / 10
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131 Report
  • Seanie
  • October 16, 2014

For Bipolar Disorder "I've been taking Seroquel for 7 years, after 20 years of delusional thoughts, mania, and large amounts of depression. It worked within two weeks, and I noticed that when I woke up each day, my delusional thoughts were getting easier to identify and let go of. It changed my life. Since taking Seroquel, I have been able to learn how to drive, work in permanent jobs, save money, travel overseas, socialize, have a successful relationship, and reconnect with the real me. I have also worked on my cognitive and emotional development and continue to attend counseling. I have gained 30 kgs, but this has probably come about due to the combination of Seroquel, inactivity, diet, and sleep apnea (of which I have only just been diagnosed)."

9 / 10
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90 Report
  • Anonymous
  • April 16, 2012

For Insomnia "I am 21 and have trouble sleeping, due mostly to my depression and anxiety. I got prescribed Seroquel (50mg one before bedtime) about a year ago, and it has helped me SO MUCH in a couple of ways, INSTANTLY - helped me sleep and stay asleep. At first, a couple of weeks, I was drowsy when I woke up, but after a month or two of taking it, I wake up feeling great. (Makes sleep amazing, and I have the most vivid awesome dreams.) Over time, taking this medication has lowered my depression and anxiety. I have noticed that hard situations and emotions are much easier to handle. I can stay calm compared to always freaking out."

9 / 10
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106 Report
  • Happy...
  • Taken for 1 to 2 years
  • March 7, 2014

For Bipolar Disorder "I was off meds for a while and thought I was fine - nope! Had a manic episode. I take 100 to 150 mg of Seroquel at night. Before this, I took Geodon and lost weight, but I had uncontrollable muscle movements. I didn't want to switch, but my family was embarrassed by my non-stop hand movements. I switched to Seroquel and feel a million times better. I sleep great (used to not sleep for days). BUT, I have gained 40 lbs. I wake up the next morning and see what I ate the night before and get so irritated with myself. It makes me want to eat everything bad for me. If I don't eat, it's like an itch I can't scratch. I don't feel foggy, but well-rested...then again, I sleep till 8 or 9 am. To me, it's worth the weight gain to feel stable."

9 / 10
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93 Report
  • words...
  • Taken for less than 1 month
  • April 23, 2021

For Schizophrenia "In the four years I've had schizophrenia I've never really had relief from symptoms despite much effort in finding a good medication and numerous hospitalizations. I honestly felt like a hopeless case seeing as I've been on Invega, Zyprexa, Abilify, Clozaril, Rexulti, Loxapine, and Resperidol. Every single one of these medications made me extremely tired. I would sleep for days only to get up to have a meal or use the washroom in some cases I was sleeping 23 hours a day.. but then I tried Seroquel XR. Within days I started feeling alive again and didn't even get the sleepiness side effect. I feel so calm and clear on this drug. I now have days where I'm completely in reality and not a thing could bother me or upset/trigger me. This medication was a literal life saver, an unexpected one too."

10 / 10
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38 Report
  • JimiS
  • April 7, 2008

For Bipolar Disorder "For many years I have been impulsive, and that impulsiveness has led to a lot of serious problems in my life. (Some of which were legal.) Seroquel has installed a 'buffer' between the impulsive thought and the words/actions that come as a result. I am now able to fully analyze a thought process and decide whether or not to act on it. I have noticed a profound change in all areas of my life, including my musical abilities. My family and I are now benefiting from a more calm and appropriate person."

10 / 10
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128 Report
  • Wildc...
  • Taken for 1 to 2 years
  • October 2, 2013

For Bipolar Disorder "I've been taking Seroquel for about a year, and I can honestly say I don't ever want to live without it. No other medicine had any effect on controlling my extreme mood swings and delusional/psychotic thinking. The sleepiness (which I now find very helpful) and morning fog were bothersome, but I've gladly adapted my schedule to allow 8-9 hrs sleep nightly."

10 / 10
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92 Report
  • Anonymous
  • December 3, 2010

For Insomnia "This medicine has changed my life. On for 2 months now. Almost didn't try because of bad postings. 46 y.o. male with lifetime insomnia, worse the last 8 years. Off and on sleeping pills and self-medicating daily with alcohol was destroying my marriage and life. Sleep 7 hrs every night without fail now. A little slow to get going first thing in the morning but otherwise feel like I'm 20 again. Taking 200mg at bedtime. Zero weight gain. Just had bloods. Cholesterol 140, Triglycerides 53, glucose 79. I work out daily, eat extremely healthy, take no other medicines, and have had no alcohol for 2 months with zero desire for it."

10 / 10
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107 Report
  • Bazzz...
  • Taken for 10 years or more
  • January 4, 2016

For Schizophrenia "I've been taking Seroquel for 17 years. I am diagnosed as schizophrenic, but for the last 10 years, I have had very few symptoms. After 6 years of being shifted from one med to another, all of which made me feel awful, put on weight, and had no effect on my condition, I was happy to be put on Seroquel purely because I felt normal. However, it still had very little effect on my symptoms. I was very reluctant to change meds again, so I stuck with it. I had my energy back, started getting out exercising, and began losing the weight I had put on. The schizophrenia was still there, but at least having a break from just sitting there with it. It took a while, but after 2-3 years, the symptoms started to decrease and kept on decreasing."

9 / 10
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75 Report
  • Selena
  • Taken for 6 months to 1 year
  • August 1, 2021

For Bipolar Disorder "This medicine literally saved my life. I wish I’d of known about it sooner in my adult life. I’ve struggled with ptsd, anxiety, pmdd, mood swings, and bad depression for 8 years. I tried every medication out there, and none of them helped. I’ve been on this for almost a year now, and I recommend it to everyone. I cried my eyes out when it hit me just how much this medication has helped. I feel normal now, and everyone tells me this is what it’s like to be and feel normal, and to be happy, to be content with life. I wish I wish I wish I would have known about this years ago. I could have saved myself a lot of heart ache. But hey, everything happens for a reason. The ONLY downside is being tired. I have to make sure I have extra time to sleep. And if I forget to take it, or don’t refill my script, I’m not sleeping that night lol. TRY IT. DO IT. It will change your life. It changed mine."

10 / 10
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  • eveni...
  • Taken for 2 to 5 years
  • April 26, 2024

For Bipolar Disorder "Seroquel truly changed my life for the better. I was on max doses of 3 drugs and still in a deep depression. (I am bipolar, with more depressive episodes than mania). It felt hopeless and like I'd hit a brick wall. Psychiatrist recommended Seroquel as they said it's best for bipolar severe depression. Once I was at the right dose, it was like a switch flipped. I could hardly believe the difference: I was pulled out of my depression, anxiety diminished, could finally sleep at night. I haven't had a depressive episode in over 2 years on Seroquel and I have never been in remission this long before. I was afraid it would make me sleepy; it only makes me tired at bedtime and I sleep soundly at night. I'm fine the next morning. My only critique would be weight gain. I lost some weight and gained it back. But, I will take stability and having gained weight over being thinner and unstable. Don't believe the horror stories: everyone is different. It changed my life."

10 / 10
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  • Jake
  • Taken for 2 to 5 years
  • April 17, 2019

For Bipolar Disorder "Have been on many meds that were inappropriately used for my anxiety and instability including high dose Depakote and tryclic anti depressants making me more unstable with unbearable antipsychotic overloads. Eventually a sedative dose of seroquel around 125-150 mg worked very well for calming down anxiety intrusive thoughts and allowing me to sleep. It is ridiculous that some of the doctors who aggressively medicate and aren't cautious because the right dose of helpful medication can be life saving while a bad approach can cause instability that caused serious problems in my life. Then unfortunately psychiatrist often blame your condition over their inappropriate treatment so it's important to be aware of what's going on with you."

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50 Report
  • insan...
  • Taken for 1 to 2 years
  • April 10, 2014

For Bipolar Disorder "Took for bipolar. Good side effects: more or less consistently put me to sleep every night. Bad side effects: gained roughly 20 lbs 6 months in, had a difficult time getting up every day, needed more sleep than usual. It helped for a while, but it mostly made my episodes less severe, did not effectively stop or prevent them."

7 / 10
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83 Report
  • Ms Br...
  • July 5, 2011

For Generalized Anxiety Disorder "I've been using Seroquel now for 4 years. I suffer from anxiety and can't sleep at night. Seroquel has helped me sleep and helps me throughout the day with my anxiety. If I feel anxious, I take a 25mg pill, and it alleviates the anxiety for me. I think it's very good for both. It has helped me tremendously."

9 / 10
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99 Report
  • Raist...
  • October 19, 2016

For Bipolar Disorder "A word of caution. I've noticed how positive these reviews tend to be. You should look-up the withdrawal effects when coming of this drug. I've been on and off medication for the last 20 years. When I came of efexor 15 years ago I couldn't walk for three days. But that was nothing compared to seroquel. And it takes 90 days for the withdrawal effects to begin to wear off. Seriously, before taking this drug you need to do some research. I would STRONGLY advise you to find another drug."

3 / 10
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66 Report
  • BABYG...
  • Taken for 10 years or more
  • May 31, 2013

For Bipolar Disorder "I was diagnosed with bipolar when I was 14 years old. I am now 34 years old. I have been on many different medications for my bipolar. Seroquel has been a wonderful medication. I take 1000mg at bedtime. I have been on it for almost 16 years. It works well for me."

10 / 10
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85 Report
  • Anonymous
  • August 1, 2009

For Insomnia "I am 49-year-old female with a lifetime of insomnia. I had been taking Ambien for sleep for over a decade for my insomnia but had been waking up during the night, cooking, cleaning, drawing, etc., so my doctor suggested I try 50 mg of Seroquel instead. I've been taking it for two weeks now, and I am sleeping and waking alert (YES!) and not semi-foggy...you all know that feeling, right? An added benefit is I am less anxious throughout the day."

7 / 10
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105 Report
  • SRRR
  • February 23, 2022

For Bipolar Disorder "THROW THIS MEDICATION AWAY!!! Honestly the worse thing to start.. I’ve been on it for years and now find out it’s caused my pancreatitis. In the past year I’ve been hospitalized 3 times due to it. I’m otherwise healthy and now may have ruined my pancreas due to seroquel"

1 / 10
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26 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.