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Seroquel XR for Bipolar Disorder User Reviews (Page 4)

Seroquel XR has an average rating of 7.3 out of 10 from a total of 106 reviews for the treatment of Bipolar Disorder. 64% of reviewers reported a positive experience, while 17% reported a negative experience.

Reviews for Seroquel XR

  • MadMo...
  • Taken for 2 to 5 years
  • August 8, 2021

"My son was on this drug for a couple of years. In the last six months maybe longer. He started seeing and hearing things. He isolated himself and started turning his phone off. A month ago my 38 year old just up and left state without telling me until he was already gone. I got a mothers worse nightmare phone call from another state. Said my son was there for self harm. He had a psychotic break down and gouged his eyes. They may have to remove his left eye. And he is blind in the right eye. I am broken. Don't let any of your loved ones take that drug."

1 / 10
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  • Anonymous
  • September 14, 2009

"Love this medication. I take it with two other mood stabilizers, an antidepressant, and another when required antipsychotic. This works wonders. I do not get tired on it and I typically take 600mg, I have gone up to 1000mg before when needed. Definitely chills me out. I do not get akathisia on this one, like I do all the other antipsychotics. Overall just wonderful. If you have had issues with akathisia before on other medicines, this would be the one to try."

10 / 10
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  • kingo...
  • Taken for 1 to 6 months
  • August 19, 2015

"Took Seroquel XR for about 2 months, experienced help with sleep issues for about a week before that wore off. Gained at least 20 lbs in this time frame, due to increased appetite and general weight gain due to the drug. Never really seemed to help my bipolar disorder- the other medicines I take do that."

2 / 10
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Frequently asked questions

  • BPNOS
  • January 22, 2010

"Was on Lexapro 20 for a while but after a bipolar NOS diagnosis, doctor wanted to remove Lexapro and go to Seroquel XR. Usually I sleep 7 hrs, after taking 50mg the first night I slept 13 hours and was barely awake after that. The next night on 100mg I slept 12 hours and was barely functioning throughout the day. I went back to 50 and then back to 100 again and repeatedly found that I was in a haze until the early afternoon. I noticed no positive results and stopped after a week. Will now try Abilify. Also, I had rather intense dreams and nightmares."

3 / 10
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  • Tammy...
  • April 20, 2022

"I have been on Seroquel XR for 12 years.I think it is overall a good medicine. I had tried several medications that didn't work. Thanks to Astra Zeneca I am better. I have better appetite. I still have some manic episodes but Seroquel XR has been the best for me."

9 / 10
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Are you taking this medicine?

  • Aloui...
  • April 20, 2017

"I have Bipolar, most the time being on Seroquel has helped settle my racing thoughts, helps me sleep at night, and helps me regulate my moods. At times I still get the highs and lows but not as severe without Seroquel. The side effects that I get is dry mouth, dry skin, increased appetite and High Cholestrol. Most of the time this medication helps me out."

8 / 10
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  • Felix
  • Taken for less than 1 month
  • February 13, 2018

"Tried Seraquel ten years ago. Ended up driving when my body when into SEVERE convulsions. Was barely able to turn around and drive back home. Then, recently, ten years later I was prescribed SEROQUEL XR. Again. I didn’t make the connection to the first time. Took the 100mg dosage two nights ago. Uncontrollable convulsions and seizures. I have restless leg syndrome and my legs were flying all around. No way to lie down and sleep, so I walked around the house for four hours, occasionally I sitting at my desk for a bit. No sleep. Then, the next day I suffered the entire day suffering from cognitive dissonance. I kept going in and out of “the moment.” And I would spend about thirty seconds in this state, then return for a minute or two. This cycle went on all day long. Third day now and back to “normal.” Not taking anything now."

1 / 10
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  • cute...
  • Taken for 1 to 6 months
  • September 27, 2017

"I had the worst side-effect from this medication. I was originally prescribed it about a year ago for insomnia related to my Bipolar 2. It worked to get me to sleep, but eventually I started to have enormous amounts to rectal pain, so I went off of it when I stopped cycling. I was put on it again this year when my cycling started again, and I again had the same pain. It was absolutely awful. So I am off of it now and never want to be put on it again."

3 / 10
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  • Anonymous
  • June 29, 2010

"Seroquel XR stabilized my Bipolar within a week. I felt no emotion at all, high or low. But I was a zombie, sleeping 18 or more hours a day on 300mg. I switched to 200mg and could function well after 8 hours sleep with only a 1 hour or so "hang over", but my job requires me to be on 24 hour call and I got called only 2 hours after taking my medication. All I could do was drool on the telephone. I'm trying Geodon now."

6 / 10
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  • CBI
  • Taken for 1 to 2 years
  • October 24, 2021

"This was a miracle med for me. It lifted my relentless depression and I was able to be stable on just seroquel for many months. Almost no side effects except small weight gain and daytime sleepiness, but that went away. Best sleep of my life on this med. I’ve hit a rough patch in life (experiencing some loss) and am in the midst of a breakthrough depressive episode, but titrating back up on lamictal and considering adding Wellbutrin eventually. I knew at some point I’d probably have to add a med, but seroquel is still an important piece of the puzzle for me. It’s definitely not for everyone, like all meds, but for me it’s great."

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  • Filthy
  • April 13, 2021

"My psychiatrist prescribed me Seroquel today for my type 2 bipolar disorder. I have been taking 1350mg Lithium and 200mg Lamotragine for seven years now but I have become toxic from the lithium because my kidneys aren't doing their job properly and my levels have been slowly rising over time. So now I'm slowly reducing my daily dose of lithium and starting on Seroquel tomorrow. I just want to know if it's a good combination."

1 / 10
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  • piki
  • Taken for 2 to 5 years
  • August 8, 2022

"I have a diagnosis of Bipolar type 1 (with long manic-psychotic episodes, and a long depression that came on when I was put on a depot - Clopixol). After a roller-coaster few years of trying everything except Seroquel XR (well, quetiapine generic) I ended up quitting medication, and back in hospital, and even homeless. Since coming off the depot Clopixol in 2020 March, due to suicidality, extreme depersonalisation and a generally nightmarish existence, and since switching to Seroquel XR 300 with lithium 600, I've been stable, and I've enjoyed a degree of stability and consistency I never thought possible with this illness. I realise psychiatric treatment is not for everyone, but with the major diagnoses, it is necessary I feel - I'm glad I persevered through many years of trial and error - the reward, only a big of weight gain, ability to feel a nice healthy range of emotions (including tears/anger, and laughter/humour) and a chance to live life as I intended. Unbelievable drug."

9 / 10
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  • Acid...
  • Taken for 1 to 6 months
  • October 24, 2022

"I was prescribed seroquel 10 ml for anxiety and insomnia. My doctor said start at 5 mg for a couple of days so my body would get used to it. Within 20 minutes I felt sedated and sleepy. I have to cut it in quarters before I take it, because otherwise I feel dumbed down and heavy like I smoked a whole pound of weed or something. My eyes even become reddish and lazy. It damn near GIVES me anxiety. I have never took the whole 10 mg because I'm terrified of how I might feel. Also if I take it after 7pm I STRUGGLE to get up at 4am for work. I've snoozed my phone all the way to 7am before just because I literally could not keep my eyes open for more than 5 seconds from feeling so tired. Like I only had an hour of sleep. Maybe it's a different result for bipolar but it isn't working for me at all."

4 / 10
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  • Scotty
  • Taken for 1 to 2 years
  • February 13, 2022

"800 mg Zaluron/seroquel 1200 mg Lithium Priadel 1000 mg Depokote 30 mg Aripiprizole Combined they are all starting to get me down from manic and to feel a bit stable again. Hoping it works. None of the above make me drowsy although I get to vivid dreams During my three hours sleep!"

8 / 10
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  • Bipol...
  • Taken for 1 to 2 years
  • July 9, 2024

"I've been on Seroquel on and off for over 16 years. My doctors would switch me to other drugs that didn't work as well. I've been on Seroquel XR 400mg for a little over a year and I have never been more stable. I'm able to hold a job, I have great relationships with my children, and my anxiety has been at an all-time low. The only downfall is that I can't sleep a wink without it. I had surgery recently and was told not to take the Seroquel with the pain meds they send me home with because apparently they interact. I didn't take it for 3 days, and apparently my body was super dependent on it because I literally couldn't sleep a wink for those 3 days. It was hell!! So I finally took it on the 4th day and I slept like a baby for 12 hours. Other than that one instance, I love Seroquel as it's the only drug that truly worked for me."

10 / 10
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  • pika
  • Taken for 2 to 5 years
  • September 7, 2019

"This drug Seroquel extended release is amazing. Way better than the regular serequel. It really helps my mood. It helps me sleep and less sedating. I don't feel like a zombie in the morning"

9 / 10
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  • Anonymous
  • February 7, 2009

"This medicine will make you fat and happy."

5 / 10
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40 Report
  • nikkk...
  • Taken for 1 to 2 years
  • June 24, 2013

"It worked well, my moods were more stable. The only downfall was that I gained 20 pounds. As a bulimic and anorexic this terrified me. I ended up going off of it to lose the weight."

6 / 10
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  • mnj
  • November 9, 2014

"Great medication helps with bi-polar. If I had anything bad to say it would be that it makes you gain weight like crazy. However other then that I sleep better then I have in twenty some years. "

7 / 10
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  • Whimpy
  • January 9, 2013

"Completely non functional, just not for me, I cut the 25 mg ones into Quarters, ONLY if I'm a little too hyper before I go to sleep."

1 / 10
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  • dnc
  • Taken for 1 to 6 months
  • May 18, 2015

"Not bad, but the weight gain and how tired it made me, eventually led me to go off of it."

5 / 10
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21 Report
  • just...
  • May 24, 2009

"Have been on Lexapro and Xanax for a year and a half but still had problems with feeling angry, irritated and on edge all the time. This works great. My kids don't have to walk on eggshells anymore."

9 / 10
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28 Report
  • Lu Lu
  • Taken for 1 to 6 months
  • February 10, 2024

"I gained 45 pounds on Seroquel XR. Other than that it helped me."

8 / 10
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  • Anonymous
  • September 10, 2011

"Made me too "hungover" and groggy the next day. I was even breaking my 50mg pill in half."

3 / 10
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  • Stefc...
  • Taken for 6 months to 1 year
  • September 23, 2014

"Worked but made me drowsy and put on weight"

5 / 10
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16 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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