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Phentermine / topiramate and Numbness: What Users Say

Brand names: Qsymia

Numbness: mentioned by 23 users (3.3%)

Based on user experiences from 692 Phentermine / topiramate reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 21.0%
tingling 12.6%
insomnia 9.0%
constipation 8.5%
headaches 6.2%
tiredness 5.5%
dizziness 3.8%
anxiety 3.6%
depression 3.5%
numbness 3.3%

Reviews for Phentermine / topiramate

Commonly mentioned side effects
  • Ano...
  • Taken for 1 to 6 months
  • January 17, 2020

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "So I have been taking it for a couple of months now and have lost a total of 50 pounds. In the beginning, the only side effects I have encountered have been dry mouth, nausea, and constipation. However, now on the third month, both of my legs have gotten numb and stayed numb for the last couple of days. I have gone to several doctors, and they are not sure what it is from. I was wondering if anyone else encountered this problem?"

5 / 10
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  • YaS...
  • September 20, 2014

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I'm 5'7 and 6 weeks ago I weighed 210 lbs. I started at the low dose for two weeks and lost 8 lbs, and at the middle dose, I lost 17 lbs more. I've had minimal side effects: toe and finger numbness that lasts for a few minutes and some dry mouth. Certainly nothing that I would consider stopping for. I love this pill. I have no interest in food and am so rarely hungry. It is pricey - please go to their website and get the first two weeks free and $100 off every month after that. It is worth it, I think I'm saving that in food costs."

9 / 10
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198 Report
  • YaS...
  • September 20, 2014

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I'm 5'7 and 6 weeks ago I weighed 210 lbs. I started at the low dose for two weeks and lost 8 lbs, and at the middle dose, I lost 17 lbs more. I've had minimal side effects: toe and finger numbness that lasts for a few minutes and some dry mouth. Certainly nothing that I would consider stopping for. I love this pill. I have no interest in food and am so rarely hungry. It is pricey - please go to their website and get the first two weeks free and $100 off every month after that. It is worth it, I think I'm saving that in food costs."

9 / 10
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198 Report
  • Pho...
  • April 4, 2017

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I started Qsymia in December 2016 and had the finger and toe numbness, trouble sleeping, and anxiety but that only lasted the first 10 days or so. In the past year, I've lost 50 lbs, and that's without a ton of changes. I noticed a huge change in my appetite. I wasn't someone that overate to begin with, which was why my weight was frustrating, but now I notice I have to make an effort to eat meals because I'm rarely hungry. I have plenty of energy to do everything I need to do. I am at my initial goal weight but now looking to go an extra 10 lbs lighter. If I add moderate exercise, the weight comes off quick which was impossible before Qsymia. I highly recommend this! It's tough the first 2 weeks but past that, it's been super easy for me."

10 / 10
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85 Report
  • Pho...
  • April 4, 2017

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I started Qsymia in December 2016 and had the finger and toe numbness, trouble sleeping, and anxiety but that only lasted the first 10 days or so. In the past year, I've lost 50 lbs, and that's without a ton of changes. I noticed a huge change in my appetite. I wasn't someone that overate to begin with, which was why my weight was frustrating, but now I notice I have to make an effort to eat meals because I'm rarely hungry. I have plenty of energy to do everything I need to do. I am at my initial goal weight but now looking to go an extra 10 lbs lighter. If I add moderate exercise, the weight comes off quick which was impossible before Qsymia. I highly recommend this! It's tough the first 2 weeks but past that, it's been super easy for me."

10 / 10
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85 Report

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  • eea...
  • May 26, 2021

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I am 59 years old, 5'6" tall, 326 pounds. On April 5, 2021, I received the basic dosage and initiated my 1500-calorie intake, as well as 7000 daily steps. As of May 19, 2021, my weight was 304. I'm down 22 pounds. I'm extremely happy with the results. Since chemotherapy in 2015, I have gained over 130 pounds. The Mayo Clinic recognized my health issues and quickly recommended Qsymia. My side effects are similar to other posters: constipation, numbness in hands, mild insomnia, and dry mouth. As for what I am doing to assist in my weight loss, I stopped drinking all carbonated drinks and no more sugar. I am now adding an additional 30 minutes of stationary recumbent bike exercise to the 7000 steps. I drink two 16 oz bottles of water every morning with my pill. I drink a minimum of 5 (16 oz) bottles a day. I use my watch and phone to track my exercise, and I document all meals on an app called MyFitnessPal. I take screenshots of all my exercise and food information and send it to my nutritionist in a weekly email."

10 / 10
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50 Report
  • Swe...
  • Taken for less than 1 month
  • March 19, 2014

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I have been taking Qsymia for almost a month now and have lost 11 lbs in 22 days. I am on a low-calorie diet. I have had several side effects like constipation, insomnia, numbness in face and legs. Any carbonated drink tastes like it's been sitting out open for a day, just flat, no fizz at all. I do feel irritable at times but most side effects I can manage, except the constipation that just plain hurts. I have an appointment on March 28th and I'll see how it goes with my progress and labs. I was at 290 lbs starting weight and I am down to 279 lbs. Seeing my belly shrink motivates me more to exercise and continue to eat healthier. It is quite expensive, but I look at it like this, I waste money on other things that don't do me any better, and this will."

9 / 10
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91 Report
  • sou...
  • Taken for less than 1 month
  • August 6, 2013

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I've been taking Qsymia for 6 days now, and I feel the random tingling feeling and numbness. With that being said, I've lost about 4 pounds so far without changes to my lifestyle. Foods do taste different. Sodas taste like metal, rice and bread taste like cardboard, and anything other than a salad, lean grilled, broiled, or steamed meats or fruits taste rather nasty. One thing is for sure, AVOID ANY DRINK WITH ASPARTAME IN IT, it will give you a monster headache and really make the tingling numb feeling really noticeable. I thought I was going to die...my head and my eyes hurt so bad. Dropped the sparkling flavored water and diet sodas, and feeling awesome. Will update in a few weeks with progress!"

6 / 10
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97 Report
  • Bea...
  • April 2, 2014

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "52-year-old female. I have now been on 7.5 mg for 14 days, 28 days total. Hunger much reduced. Side effects: headaches; ringing in my ears lasted about a week. Still have slight numbness in cheeks. Have lost 13 lbs in 28 days, the most weight I have been able to lose in 12 years - I am thrilled. My morning blood sugar was 150 to 180, now 70 to 120. Oh...and I've stopped snoring!"

10 / 10
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84 Report
  • sjs...
  • Taken for 1 to 6 months
  • June 15, 2013

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I am a 29-year-old male. 6'2''. I started the trial dose of Qsymia on 1/16/13 weighing 315 lbs. I moved on to the 7.5/46 dose. Today (6/10/13) I weighed in at 221. A month ago I asked the doctor to increase my dose to the 11.25/69 mg as I was starting to eat more. That is when I was not able to sleep, and then halfway through taking that dose, I noticed I started having numbness in my right foot/calf (which I guess is normal). I already went back to the doctor and asked to be put back on the lower dose, even though it will slow my progress. I still have 25 lbs to go. I hope going back to the lower dose solves this problem. This is not a miracle pill, you HAVE to eat healthy and exercise while taking it. You must make a lifestyle change on it."

9 / 10
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83 Report
  • get...
  • Taken for 6 months to 1 year
  • August 20, 2014

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "Update: Went to the doctor on 08/02/2014, down 32 pounds. I really love these pills. Really no side effects. A little numbness in the fingers but goes away quickly. Will continue to take until I reach my weight loss goal of 50 pounds."

9 / 10
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76 Report
  • mis...
  • March 11, 2013

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I'm 32, 5'7", and female, and had a beginning weight of 250 lbs. I just started my third month of Qsymia, and I am down 33 lbs. I have put myself on a calorie-restricted diet of 1200 calories a day, and I work out 3-4 times a week. The pills do help with my hunger and cravings. At first, diet sodas tasted really bad, and I had episodes of facial and hand numbness and tingling, but those are the only side effects I've experienced. This, all in all, has helped me tremendously do what I couldn't do on my own. Some of my motivation to stick to it also is the cost. At $150 a month, I can't afford to mess this up."

10 / 10
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70 Report
  • mis...
  • March 11, 2013

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I'm 32, 5'7", and female, and had a beginning weight of 250 lbs. I just started my third month of Qsymia, and I am down 33 lbs. I have put myself on a calorie-restricted diet of 1200 calories a day, and I work out 3-4 times a week. The pills do help with my hunger and cravings. At first, diet sodas tasted really bad, and I had episodes of facial and hand numbness and tingling, but those are the only side effects I've experienced. This, all in all, has helped me tremendously do what I couldn't do on my own. Some of my motivation to stick to it also is the cost. At $150 a month, I can't afford to mess this up."

10 / 10
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70 Report
  • Elf...
  • Taken for less than 1 month
  • May 8, 2021

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I am a 58-yr-old female, 173 lbs, 4 ft 8. Today is my first day on the med. I had a little numbness in my hands, but it subsided in no time. I'm not hungry. Tried to eat half of a sandwich and took 2 bites and wasn't hungry. We celebrate Mother's Day tonight at my daughter's with her family. We'll order pizza from our favorite place, we'll see what happens. I'm drinking splash-flavored water. Good luck, everyone. Go to the doctor on 5/28/21. Will let you know what happens."

8 / 10
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28 Report
  • Sta...
  • July 25, 2016

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I've had great results with this medication, with some of the side effects listed: dry mouth and numbness (in my toes). This medication, if used properly, will help you lose weight and aid you in your journey. I best describe it to my friends as, 'feels like you just ate a Thanksgiving meal!' Every time you take the medication, I suffer from migraines, and this medication has been the one that works for me! If you go to the Qsymia website, they offer a savings coupon, which works at every pharmacy! If you just eat junk every month and hope to lose lots of weight, it won't happen! The healthier you eat, the more this medicine will help you! Good luck!"

9 / 10
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46 Report
  • Goa...
  • Taken for 1 to 2 years
  • February 2, 2016

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "Female 5'9, beginning weight 221. Lost some weight on my own. Began Qsymia. Lost 50 lbs in 6 months with a great low carb diet and exercise. Maintaining after 1 year but finding I am hungry all the time now. I still take the drug daily. Side effects: my hands would get numb in the beginning."

9 / 10
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47 Report
  • IWT...
  • Taken for 1 to 6 months
  • April 16, 2017

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I posted previously after 2 days on the component drugs that make up Qsymia. I am 61 and had reported no side effects. It has now been 6 weeks. I have had side effects, but only minor - some dry mouth, difficulty sleeping if I don't have a glass of wine before bed ;), some numbness a few times in my face, and that's it. I'm down 14 pounds. I have made a very conscious effort to take off weight and sometimes question whether the Rx works, but I do know that I simply have no cravings. I have no pull to buy junk food. I have gone to a whole food diet, have had no sugar for 6 weeks, low carbs, just added a workout program 2 weeks ago, and continue to drink 100 oz of water daily. Because it has been fairly easy, I do credit the drug."

10 / 10
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34 Report
  • Liq...
  • Taken for less than 1 month
  • December 25, 2015

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I have been on the Qsymia for 3 weeks now. I wanted to wait a few weeks to give a review. I have a very slow metabolism, so I did not lose as much as some in the first two weeks upon taking. My weight started at 198. I am down to 193. So I have lost 5 lbs in 3 weeks. But that is without cardio. My appetite is suppressed. Dry mouth. So drink a lot of water. Tingling, almost numbness in my feet at times, but it goes away shortly after. The medication, if not covered or with the free trial, is expensive. So be prepared. I guess it is cheaper than weight loss surgery. But it's no magic pill neither. Like any other pill, you must eat right and exercise to lose the weight. Well, that's my take anyway."

8 / 10
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38 Report
  • The...
  • May 4, 2016

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "First day... First day I felt the side effects. At first, I was okay. As the day went by, my eyes felt dry. Then my left arm and legs felt numb. I got really hot and anxious. Come 9:30 p.m., my eyes and top of my head had such pressure. Not to mention I was ravenous all day."

1 / 10
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25 Report
  • seb...
  • March 3, 2015

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "I have just stopped taking Qsymia after being on it for 15 months. I have lost 71 pounds, and I am wearing size 10 jeans! I never thought I would see that day again after five kids. I had very few side effects, like dry mouth and some toe tingles and occasional numbness in my fingers and toes that would come and go. Those were mostly in the beginning of taking it. I would recommend this medication for weight loss! Now I am eating small portions because my stomach has shrunk and am able to exercise three to four times a week, and I plan to continue all of these things. This is the only weight loss drug I have ever taken, but I am sure glad I did after struggling for five years with no success on my own."

10 / 10
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23 Report
  • Dis...
  • August 13, 2015

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "Do not waste your money or further your health. Side effects on this drug, it does not work. Makes you very exhausted and tired. I had numbness/tingling in the hands, arms, feet; twitching in my eyes; dizziness; trouble sleeping; dry mouth; confusion; cloudiness; and extensive heartburn."

1 / 10
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21 Report
  • Sag...
  • Taken for less than 1 month
  • July 4, 2015

Phentermine / topiramate for Weight Loss (Obesity/Overweight) "The first week seemed fine enough at first: tingling in feet and hands, dry mouth, and diet soda tasted awful, so I stopped drinking it. After one week, I noticed the sluggishness when forming a thought, the forgetting things moments after the thought entered my brain, and tingling in my face. I also had some issues sleeping. Talked with my doc, and she confirmed all of this was normal due to the Topamax, and it was up to me to continue. I had already purchased the month's dose at the time I got my free dose, so I decided to stick it out and try it. The first day of the doubled dose was absolutely awful. I felt anxious, and my face was numb and tingly from 6 a.m. to 6 p.m., no exaggeration. I immediately stopped. Lost 12 lbs but not worth it."

2 / 10
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12 Report
  • Toa...
  • Taken for 1 to 6 months
  • April 2, 2016

For Weight Loss (Obesity/Overweight) "I have been on 25 mg 2x a day for a month now for weight control and as a mood stabilizer. When I started, I weighed 235 lbs and I am 5' tall, and I have lost 11 lbs. It makes it so I just don't want to eat as much. I feel full very quickly. I get thirsty very fast, so I keep drinking a lot of water, but that isn't a change for me. I have noticed that my feet and hands go numb, but it is worth the weight loss. My vision is blurred a bit even with my glasses, but nothing terrible. I'm hoping to keep going and continue with my weight loss."

8 / 10
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9 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.