Phentermine/topiramate Interactions
There are 417 drugs known to interact with phentermine/topiramate, along with 21 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 150 are major, 264 are moderate, and 3 are minor.
- View all 417 medications that may interact with phentermine/topiramate
- View phentermine/topiramate alcohol/food interactions (3)
- View phentermine/topiramate disease interactions (21)
Most frequently checked interactions
View interaction reports for phentermine / topiramate and the medicines listed below.
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Benadryl (diphenhydramine)
- Contrave (bupropion / naltrexone)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Depakote (divalproex sodium)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Flonase (fluticasone nasal)
- Lamictal (lamotrigine)
- Lexapro (escitalopram)
- Linzess (linaclotide)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- Mounjaro (tirzepatide)
- Mucinex (guaifenesin)
- Norco (acetaminophen / hydrocodone)
- Ozempic (semaglutide)
- Probiotic Formula (bifidobacterium infantis / lactobacillus acidophilus)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Trintellix (vortioxetine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Wellbutrin (bupropion)
- Wellbutrin XL (bupropion)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Phentermine/topiramate alcohol/food interactions
There are 3 alcohol/food interactions with phentermine / topiramate.
Phentermine/topiramate disease interactions
There are 21 disease interactions with phentermine / topiramate which include:
- cardiovascular
- glaucoma
- oligohidrosis/hyperthermia
- agitation
- cardiac disease
- glaucoma
- hypertension
- psychiatric disorders
- pulmonary hypertension
- substance abuse
- suicidal tendency
- renal dysfunction
- metabolic acidosis
- renal dysfunction
- diabetics
- dialysis
- liver disease
- angle closure glaucoma
- hemodialysis
- liver disease
- nephrolithiasis
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More about phentermine / topiramate
- phentermine/topiramate consumer information
- Compare alternatives
- Reviews (692)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anorexiants
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
