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Zofran ODT and Constipation: What Users Say

Constipation: mentioned by 4 users (6.6%)

Based on user experiences from 61 Zofran ODT reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 39.3%
headaches 23.0%
vomiting 16.4%
constipation 6.6%

Reviews for Zofran ODT

Commonly mentioned side effects
  • Gin...
  • Taken for 6 months to 1 year
  • February 4, 2021

For Nausea/Vomiting "I have extreme anxiety, which causes me to have stomach issues and be constantly nauseous. I love this medication, but the only side effect I have is constipation. I usually just take a Senokot or just eat the Fiber 1 bars. It works quickly. It doesn't taste the best, but it's absolutely worth it."

10 / 10
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17 Report
  • Cat...
  • Taken for less than 1 month
  • February 22, 2021

For Nausea/Vomiting "Horrible drug for me. Actually makes me nauseous and throws up. Nothing tastes right on this medication. One dose had me throwing up and nauseous, not able to eat for a couple of days. One dose had me constipated for about 5 days before I was back to normal (with taking stool softeners Rx after surgery). May work for some, but for me, it’s a NO go."

1 / 10
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19 Report
  • vit...
  • Taken for 1 to 2 years
  • November 8, 2024

"I had hyperemesis gravidarum during my pregnancy, and Zofran was the only medication that allowed me to feel 'okay.' I was prescribed 8 mg ODT every 6 hours. This medication truly kept me and my child alive during that time. I also have had it prescribed for kidney infections and kidney stones. Side effects include severe constipation, and it can cause headaches. Benefits include not vomiting all over the place."

10 / 10
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0 Report

Frequently asked questions

  • Cha...
  • August 18, 2016

For Nausea/Vomiting "This medicine did nothing except constipated me and give me a headache!"

1 / 10
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18 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.