Mirtazapine for Major Depressive Disorder User Reviews (Page 2)

• Anony...
• Taken for 1 to 6 months
• December 29, 2015

Remeron (mirtazapine) "Having failed most SSRIs, Remeron was a real surprise. It calmed me, helped me sleep, helped me focus, but most importantly had almost no side effects. My appetite went crazy the first week but mellowed out afterwards. I get pretty drowsy about an hour after taking it, so I only take it at bedtime. I had to drop from 45 mg to 30 mg due to it amping me up rather than sedating. Works fine, no tolerance type effects unlike Z-drugs."

• kake
• April 12, 2020

"mirtazapine has proved to be a sanjivini (life saver) for me..tired with almost all antidepressants and lost all hope. For a year I had been in pathetic condition and had major depression with many symptoms like hot flashes and suicidal thoughts. Tried this medicines and after few days I was completely recovered. I would recommend it only if you hv tried few first line treatment as I had. It did increase my blood glucose level. I would suggest to all reader please do not leave your hopes as one or another medicines will help you sooner or later..god bless us all"

• LJM
• Taken for 5 to 10 years
• May 25, 2024

"Mirtazapine is an underrated medication for mood & anxiety disorders, perhaps due to it being used at insufficient doses. The 30mg dose has worked well for me for many years now. Side effects are mild, with an increased appetite an hour or so after taking the tablet and a dry mouth in the morning being the only two I've experienced."

• Vinyl...
• Taken for 1 to 2 years
• May 15, 2015

Remeron (mirtazapine) "This is perfect for sleep at 7.5 or less. Get to sleep easily, with no worrisome thoughts before bed. I was taking it for depression after a no-go with Prozac. I couldn't handle the fatigue at therapeutic dose, and now I use Wellbutrin XL 300 in the morning and Remeron 7.5 at bedtime. I take the Wellbutrin at 6 am then go back to bed. When I get up at 8, I already have a lift from the Wellbutrin, one cup of coffee, and absolutely no fatigue. Happy, less anxious, lost a few pounds, and no sexual problems. I love this combination, and don't feel a need to change or add anything. I am curious how a higher dose of Remeron would be now, but I would hate to lose the fabulous sleep effect I get now. I am guaranteed to sleep within 30 minutes. Great meds!"

• LMF
• Taken for 6 months to 1 year
• April 17, 2014

"I find this medication amazing! I can sleep really well on it although I have quite epic dreams which I remember when I wake up. Mirtazapine makes me feel peaceful and calm. I feel in control, less panicked and with the added bonus of sleep, I feel my overall mental health is improving. My appetite has increased but I have been told that it will stabilize after 12 weeks. I have no loss of sexual function and feel more in tune with myself than ever before. I am being observed for bipolar and mood disorders. This medication is a godsend to me. Only thing I can say is if you need to be up early take it 10/12 hours before you need to get up, I take it between 7 and 8pm and get up fresh at 7am."

• medta...
• September 7, 2018

Remeron (mirtazapine) "I have taken this med for over 2 years. I've been suffering from insomnia, anxiety, and depression my whole life. I found that nothing that could help. Every night I tossed and turned, waking up every 2 hours. The first night I took this, like magic, I slept a whole night without waking up. And every night since then it has worked. However, BEWARE, it will make you binge eat. You have NO control over it. Studies say weight gain from this med only affects like 15% of people. Use look at the reviews on here and across the internet–it's more like 90%. I've always been skinny and I put on 14 pounds within a month of starting it. I quit for a week, which made me extremely depressed and unable to sleep, but I immediately lost all the weight. But I was so depressed, it hurt, so I got back on it. That's why I give this a 7, it's a conundrum, it helps so much with insomnia/depression/anxiety but it makes you FAT. Don't try this med unless you've tried ALL other SSRI's and sleep meds."

• Sweeks
• January 17, 2016

Remeron (mirtazapine) "My experience with Remeron is short. It worked wonders for me, but I stopped it as it causes awful weight gain. 21 pounds in 4 weeks. I looked pregnant. It made me more depressed. I would just eat. It does something to your brain that makes you feel as though you are never full. At night, I would sneak food. I could not stop. I was at 30mg. I've heard 15 mg is worse for weight gain. Also, this drug is also given to elderly patients who are undergoing chemotherapy and also given to people with eating disorders (bulimia and anorexia). As I said, in one respect, it did wonders for me with anxiety and depression and stopped the voices in my head and helped me sleep. But I couldn't go through gaining any more weight."

• arnold...
• Taken for less than 1 month
• May 11, 2017

Remeron (mirtazapine) "I have been anxious, paranoid and depressed since puberty (10 years). Doctors have tried SSRIs, SNRIs, and benzos, but nothing seemed to be working. The doctor wrote a script for Remeron. I was skeptical at first, and the initial side effects scared me (slurred speech, drowsiness, blurred vision), however I kept with it and I feel so much better. It is relieving being able to live without thinking I am about to get fired, or if I am getting fat (which is ridiculous. I actually have an eating disorder and I am clinically underweight). My neurotic paranoia seems to be somewhat cornered and I no longer depend on alcohol to keep me under control. I have only been on the drug for a week at 15mg. Hopefully this journey is almost over."

• Allsw...
• June 21, 2017

Remeron (mirtazapine) "I have taken Remeron for over 6 years at 30mg before bedtime to treat life long suicidal depression and debilitating social anxiety. In the first few days of taking it I can say it was like a switch put to normal. It knocks me out within 1/2 hour of taking it and it is not possible to wake me into a coherent and alert state for at least 5 hours, that isn't an issue for me and the family is used to it now also. The hours of guaranteed sleep is an added bonus. I have my life back, I no longer have social anxiety & I can deal in very high pressure situations perfectly fine. I have noticed a worsening short term memory issues but given my line of work I can't say it has relationship to the med, & I will not go off med to find out."

• Loey
• April 2, 2020

"Mirtazapine was a godsend to me. I had tried all the anti-depressants without success. I had given up when I was having a very difficult time maintaining housing, caring for my mother who has dementia and losing my daughter and grandkids to Canada where I can't afford to visit. My world was falling apart and the depression was very serious. My psychiatrist prescribed Remeron (mirtazapine) and in a day or two I saw the world in a completely hopeful way where before mirtazapine I believed life wasn't worth it anymore but couldn't do that to my sweet little girl. My only child. My only side effect was enjoying food! I gained 25 pounds but I could use them. I had no appetite at all before."

• Benso...
• Taken for 1 to 6 months
• July 22, 2023

"I was in a very deep depressive hole due to a combination of awful events that I was going through. I tried escitalopram (which kinda worked for a while, but with severe sexual side effects) and venlafaxine (it didn't help at all). Then my doctor put me on 30mg of Mirtazapine and in two weeks, I felt alive again. It didn't make me happy or euphoric, but it took me away from that hole, and now it literally blocks any depression that may come from life's occasional misfortunes. The only side effect is that it increases my appetite, which in my case is helpful since I'm pretty skinny. The only downside is that it's a bit more expensive than other antidepressants, but I don't really mind. It's the best medication I've ever taken. Solid medication overall."

• G-Dub
• Taken for less than 1 month
• August 20, 2017

Remeron (mirtazapine) "This medicine is a godsend. Being 100% honest I didn't like it because of the vivid nightmares but THEY DO STOP WITH CONTINUED USAGE. Don't give up too soon. The vivid nightmares stopped after my 5 day of taking this drug. Now, 2 weeks later my nightmares are gone and have normal dreams that don't involve death, violence or carnage. I sleep well and awaken rested. Some days there is a little groggy feelings in the morning but they wear off as you start moving. A cup of coffee helps as well. My appetite has increased and several people complain of weight gain. YOU WILL GAIN TOO MUCH WEIGHT IF YOU STAY SEDENTARY. I started lifting weights and doing planks and push-ups. That keeps the weight gain at bay."

• Sarah...
• Taken for 1 to 6 months
• February 17, 2017

"Hey everyone on mirtazapine! I've been on cymbalta, Effexor , trintellix and Prozac . Prozac was good but remeron/mirtazapine works better for anxiety by far! I started suffering from anxiety when I was 12 and remeron/ mirtazapine has given me "wings to fly" I can drive relaxed and I don't ruminate over things and make myself sick with worry so in turn my depression eases up because I'm not consumed with dread. The only downside is I feel hungry ALL the time but I use willpower . For snacking, I cut up celery and carrots and drink cold green tea instead of eating anything and everything because if you're not watchful , I guarantee you'll put on a lot of weight. I basically had to get use to being hungry. All the best"

• faith
• November 18, 2015

Remeron (mirtazapine) "Just started taking this med again. I've been on more than I can count over the years. The only downfall I've had is the daytime foggy feeling which I'm hoping will subside over time. I've only been taking this less than a week and my depression symptoms have greatly improved as well as I sleep well every night. Appetite has gone up for me as well but not a concern for me at this point. Very happy overall. I will post again in a few weeks to give another update"

• sam12...
• August 19, 2014

"Once I got over the initial cravings and grogginess (they both passed after a few weeks) it was like a dark cloud was lifted, and I could finally see clearly - completely without the classic numbness and lack of personality that other common antidepressants have. Absolute life-changer."

• Dpl
• Taken for 1 to 6 months
• August 31, 2023

"Life changing, been a chronic insomnia for over 20 years. Now I can finally sleep. I've been on 15mg for over 6 weeks now and my sleep is amazing, around 8 hours. Normally, I was lucky if I could get 5 or 6 hours. I've tried everything, spent thousands, tried every recommended potion, and so on. Mirtz is life-changing. Luckily, I am supplementing with Ozempic, a weight loss injection which I get privately, which stops any hunger on Mirtz. I tried Mirtz last year and had to stop after 5 days because I was eating 5000 calories a day and gaining fat rapidly. So I am experimenting with Ozempic for over a month now and it's working perfectly. I haven't experienced any side effects from either Mirtz or Ozempic. Life-changing stuff, guys. This is worth a million pounds to feel like this. No money or anything in the world can compare to sleeping well."

• JeNnY...
• Taken for less than 1 month
• January 8, 2023

Remeron (mirtazapine) "I am an addict. I started taking Remeron at Recovery Works about 4 weeks ago. I have always had trouble sleeping due to many many years of drug use so they started me on 15 mg it wasn't working so my dosage was increased to 30 mg. Within 20 minutes after taking it I am ready for bed. I still wake up 1-2 times every night but I have had no trouble falling asleep whatsoever. Also, my craving to use has dramatically decreased. I don't feel like I am dependent on it but I definitely want to take it every night before bed. My appetite and weight have remained under control and normal. I do feel a little "foggy" in the mornings but it usually subsides and I am not drowsy or tired throughout the next day. This drug was the answer to my insomnia. Definitely a plus for people in recovery."

• Tristan
• October 21, 2016

"I have been on Mirtazapine for 2 months now. I have a history of major depression, suicidal behavior and anxiety. I was on Sertraline (Zoloft) for 1 year but discontinued after I felt 'better'. 6 months later, in April this year, I relapsed. But Sertraline didn't work and I needed a new anti-depressant. Mirtazapine helped with my sleep from the first night I took it. and within a week my mood was much better. 2 months on and I am elated, sleeping better and in general feel amazing. And this is only on a 15mg dose! My appetite has also improved and the only side effects I have been having with Mirtazapine is drowsiness. Which was a benefit in my eyes, as it helps me fall asleep. No more insomnia, no more depression and no more anxiety!"

• cjoy
• Taken for 1 to 6 months
• April 6, 2015

Remeron (mirtazapine) "No matter how much sleep I got, I was constantly tired. I could barely function during the day. And when I was functioning, I wanted to eat EVERYTHING. In 2 months I ended up gaining 15 lbs, which definitely did not help with the depression."

• Weight...
• Taken for less than 1 month
• December 1, 2023

Remeron (mirtazapine) "Gained 20+ pounds in a month on Remeron. I work out every day and always maintain a calorie deficit, but still excessively gained weight. I took a DNA test, and it turns out I'm not compatible with this medication and experienced significant symptoms. I would suggest to everyone to get a DNA test to see which medications will or will not work for you."

• Love
• April 26, 2021

Remeron (mirtazapine) "I was taking this medication for six years and it was life changing. I was struggling to gain weight I never had appetite and I was depressed and no medication seemed to work but remeron was the only pill that worked for me. Unfortunately I put on 40 pounds and I have an almost overweight BMI so I will have to stop this medication. This medication won't "cure" your depression but it's as if nothing seems like a big deal when you're on it so therefore you feel less stressed and anxious."

• Anony...
• Taken for 2 to 5 years
• August 30, 2017

Remeron (mirtazapine) "I have been taking Remeron for about three years, at various dosages. It does a great job of handling my depression without aggravating my anxiety. It also gives me severe munchies, especially for carbs. But otherwise I have no side effects. Which is a first with me and antidepressants; the SSRIs in particular wrecked me. My doctor told me that usually, people who can't take SSRIs will be able to tolerate Remeron."

• Rocco
• Taken for 1 to 2 years
• October 19, 2022

"For me, mirtazapine has been a miracle drug! I’m not exaggerating. I have major depressive disorder and have been taking antidepressants since I was 11. I’m 32 years old currently. None of the SSRI’s on the market have ever helped me. SNRI’s don’t help either. It’s like swallowing a tic tac and expecting medical results. Mirtazapine has given me my life. It’s given me hope for the future. My depression has gotten worse with age. I developed psychosis with the depression in my late 20’s. The doctor who put me on Mirtazapine did so during a major depressive episode with psychosis. I was out of work and didn’t expect any results from this drug. I rolled my eyes thinking okay great! Another stupid pill. I saw results almost instantly. I slowly started coming out of the fog. Within two weeks I was back at work. I’ve been on it for a couple of years and have not experienced depression since starting the med. I don’t plan to ever stop taking it."

• NY 50
• Taken for 1 to 2 years
• December 3, 2014

Remeron (mirtazapine) "Have often extremely severe chronic depression/anxiety and Crohn's disease. My Crohn's Disease can give me a great deal of acid reflux so much to where I now have a hiatal hernia. Remeron did wonders for not only my MDD mixed with an SSRI (Prozac, Paxil, Wellbutrin, etc) settled my stomach and helped me sleep a bit better. It doesn't work very well any longer for sleep. I tried getting off it at one point and I went totally mental! It was only initially making me constipated for the first month , but it helps me hang on somehow."

• Mary
• Taken for 1 to 6 months
• January 7, 2022

Remeron (mirtazapine) "I was in another deep dark place. Have been on lexapro for years because I struggle w MDD. It seems the lex doesn’t help much like it used to. When I go downhill, my stomach is affected. I lose my appetite and can barely eat. I get these gnawing hunger pains, and eat to get rid of them, but then shortly after I’m hungry again but nothing sounds good or tastes good. I’m afraid of trying new meds. It’s so hard. So many don’t help and you have to be on them for quite awhile to know if they work. I’ve tried several in the past and they gave me chest pressure/pain. Unusual, but it happens. Didn’t want to try remeron but I was desperate. God heard my many prayers and many who were praying for me! Started feeling better and eating normal within a week! Crazy dreams and shaky for awhile, but that got better. Also, am gaining weight back that I lost."