Mirtazapine for Depression User Reviews (Page 4)

• Anonymous
• Taken for 1 to 6 months
• May 30, 2023

"I was prescribed 15 mg/day for depression with insomnia. While my sleep improved, I became very irritable and quick to anger. I had no patience. In addition, in only 4 weeks on this drug at what I was told was a low dose, I gained 10 pounds. I had terrible cravings, particularly for sweet foods, which is not typical for me. Even with regular exercise, I could not avoid the extra pounds. I am coming off the mirtazapine."

• scarl...
• August 1, 2013

Remeron (mirtazapine) "I have been prescribed Remeron for about 8 months now and it is a miracle. It not only helped me put on weight when I needed to because I have lost so much from all the anxiety, it also gave me an amazing night's sleep every night. Yeah, it does give you some crazy dreams sometimes and you might gain a few pounds, but your quality of life is so much better. I was so happy the next day when I woke up. I finally felt like I figured it out. I say yes to the Remeron Cycle."

• Jay
• June 4, 2019

"I have severe PTSD and depression. Started 15 mg mirtazapine worked up too 45mg with 100 mg topiramate and 9 mg melatonin ( oh and please taper up on the topiramate if you will not remember how to get home lol ) yesterday I told myself that this is honestly the best I have ever felt . This coming from a 100 service connected combat veteran with over 15 psyc ward admissions and 3 suicide attempts."

• niamh...
• Taken for 1 to 6 months
• October 2, 2020

"I’m on mirtazapine 15mg. It works for me but I’m asking my doctor to up the dosage soon, as I’m still not 100%. I experienced severe side effects on SSRI’s (prozac), so this is a good alternative (as it’s a NASSA). The side effects I experienced were quite bad lethargy and tiredness for the first 5 days or so, but after >2months on it now, it doesn’t make me tired at all now. I’ve also experienced weight gain, but that outweighs the benefits of this drug, so I’m happy to stay on mirtazapine despite that. Overall, I would definitely recommend this drug, especially to those who can’t be on SSRI’s or SNRI’s. ( also I’m in the UK, so the insurance questions don’t really apply to me, but I pay the standard £9.50 or so for my prescription. )"

• kmllml
• Taken for 6 months to 1 year
• February 1, 2014

Remeron (mirtazapine) "I have been on Remeron since last April. Wonderful!! Nothing else worked...tried everything in the past 4 years. Gained 20 pounds but was so happy to feel better until my blood work showed a high increase in my cholesterol which is stated in info so check yours out. I am now trying Paxil but if does not work will have to go back on Remeron and a Cholesterol pill which I am not happy about but the good outweighs the bad. Anyone else have this problem..."

• bumarel
• June 16, 2016

Remeron (mirtazapine) "At first, I took Remeron and I was knocked out for a full day. I was underweight and had panic anxiety. This really helped me. After the first day, my body seemed to adjust to Remeron and by the 3rd day, I didn't have any tired feeling at all. It definitely helped me with sleep. I am now on 30 x 2 tabs a day and have been on this for years. I am actually afraid to get off of it. It has helped me through very difficult times."

• eddie...
• Taken for 2 to 5 years
• August 29, 2013

Remeron (mirtazapine) "They gave me Remeron in the hospital. I took it for two and a half years. It worked wonders for me. I have had no luck at all with SSRIs. My doctor told me that usually people who have no luck with SSRIs usually have good luck with tetracyclic antidepressants. The only drawback is I gained 85 lbs, which, needless to say, did not help my self-image. I'm considering Ludiomil (maprotiline)."

• jmez
• Taken for 1 to 6 months
• March 23, 2021

"I envy so much all you people who have had benefit from this medication. The only thing it helped me with was pretty much instantly I was sleeping again (6-8) hrs per night compared to the 3 hours leading up to taking this medication. Despite constant exercise, within 2 weeks I'd put on 6kgs around my mid section. I was told it can take up to a month to work properly. It's now been just over a month that I've been on 30mg and I can completely understand why people commit suicide. Constant despair and crying over things that aren't relevant. Zero motivation or energy to do anything. I see nothing but despair and pain in my future. I will take my chances with no medication at all."

• Mal...
• Taken for 5 to 10 years
• August 31, 2015

"After years of chronic depression and a significant suicide attempt, I was institutionalized. During this time, the supervising psychiatrist prescribed mirtazapine. This drug saved my life. I am on a high dose, 60 mg before bed, but I have noticed no side effects other than a more restful night's sleep (I was an insomniac). My mood is entirely stable now, with any depressive episode being minor and totally manageable. There has been no noticeable stupefying effect, and I am not in any way sedated. In fact, my career has taken off since I commenced taking this drug. I understand that it is not for everyone, but I am one of its success stories."

• Anonymous
• Taken for 5 to 10 years
• December 25, 2019

"I take this mirtazapine for anxiety/depression/insomnia, started at 15mg but been on 45mg for most of the 8 years. It has robbed me of my young adult years and made me diabetic. At first it helped with sleep and generalized anxiety, but as it became less effective and the dose increased I became more and more apathetic, unmotivated, lazy, loss of personality, loss of feeling of empathy and affection towards others. It made me okay with sitting around being alone and doing nothing. Now it’s completely pooped out and all I’m left with are the side effects. Tapering down is also a struggle with severe withdrawals. I highly advise people to stick to medications with more of an evidence base- SSRIs, SNRIs, benzodiazepines, TCAs, and MAOIs... none of these atypical antipsychotic garbage. Mirtazapine basically is an atypical antipsychotic but without the dopaminergic receptor antagonism. Stay away from this garbage."

• Anonymous
• August 2, 2012

Remeron (mirtazapine) "Great, SSRIs do next to nothing for me but this has helped a TON. I tried Zoloft, Paxil, Prozac, etc., and they did very little for me but the week I started on Remeron 30mg, I felt so much better, almost like myself again."

• DaleH
• September 22, 2009

Remeron (mirtazapine) "I have been on Remeron (now Mirtazapine generic) for about 9 years now. It works great and I have NO sexual side effects, in that I can easily have an orgasm, which other SSRIs that I tried would not allow."

• cerem...
• Taken for less than 1 month
• June 25, 2013

Remeron (mirtazapine) "Only been taking Remeron for anxiety, for a week at 15mg. I forgot to take it at night, so my days were a type of groggy I've never experienced before. Strange but not unpleasant. It gives me tremors and cravings, but my anxiety just vanished. I lowered the dose to 7.5mg due to it being strong on the sedative side. I also have depression so I look forward to combating that, now that my anxiety is under control."

• Mirta...
• January 27, 2013

"So far I haven't seen anyone on here that's been on Remeron/Mirtazapine 45mg at night for more than 6 years. I've been on it for 11 years. I was put on this medicine in 2002 after my daughter was born. To save all the details my physical and mental health went out to rest somewhere leaving me in a body and mind that didn't belong to me. They tried me on every medicine available and nothing worked. The negative long term of this has been: weight gain, dizzy sometimes, dehydration and laziness. The positive is it gave me my life back. I, like others here, have found it's notorious for appetite. I could eat sugar right out of the bowl. I have had to make myself be more disciplined in my eating and exercise. I combat dehydration by keeping a cup of water with ice in it filled and drink on it all during the day. I am also moving into menopause so have to be very careful. I've heard some talk about the nightmares. Yep, have them too but only if I eat sugar before bed. Lay off the food 4 hours before you go to bed and it will get rid of those monsters under your bed. I have post-traumatic stress disorder and that causes most of my nightmares. Still, my sleep is awesome. I still have some anxiety from time to time but use Klonopin 0.5 to cut the edge off only when needed. I tried going off about 5 years ago and after about 3 days I couldn't sleep, think, or operate at any type of normalcy. I will have to add I also gained a concentration level I never had before. I went from a school drop-out that couldn't learn to a 3.9 GPA (40-year-old) who loves to read and learn! Compared to all the other stuff out there (and their side effects) I would have to say Remeron has proven to be the very best antidepressant I've ever taken."

• Ashle...
• Taken for 1 to 6 months
• February 14, 2020

"This drug really worked for my DEPRESSION and INSOMNIA. It really helped me, BUT... I just could not control my appetite. As soon as I woke up, my first thought was eating and after eating I was thinking what to have next. My hunger was so out of control that I would eat until I was sick. I ended up gaining 25 lbs in 2 months. I had munchies from dawn to dusk. It was horrible. I don’t know if anyone else had this happen, but had to get off of them and since have lost 20 lbs of the 25 I gained. I would recommend if you can control your hunger, because I sure couldn’t. "

• itget...
• Taken for 1 to 6 months
• July 27, 2017

"I suffered from insomnia, anxiety and depression. Over course of 2 years I have tried citralopram & sertraline. None of these have been as effective as Mirtazapine, to the point where friends, family & colleagues noticed huge positive changes in my personality. I started on 15mg which instantly cured my insomnia (WOW!) & a lift in mood (after a week). After 2 weeks I requested my GP put me on a standard dosage of 30mg. I have been on this for 2 months (best effects after week 4) & I FEEL GREAT! I am happy, outgoing, eating and sleeping properly again &finally feel the old fun, strong me is coming back. There are odd bad days but now it is easier to SNAP OUT OF IT & get back on track. THANK YOU MIRTAZAPINE FOR GIVING ME BACK MY JOIE DE VIVRE!"

• Jimmy
• Taken for 1 to 6 months
• February 18, 2024

"When I was first given Mirtazapine, it was like a miracle. 15mg. A wonderful night's sleep, and I felt fine. Even my troublesome dry skin cleared. But events and health changes made me think I should cut down to 7.5mg, and then not take it on holiday so I could have a drink. Then I took it after I had just had prostate surgery, and it had a terrible effect with whatever the surgeon had used. When I got home, I tried it again but had awful dreams no matter what dose I took. After speaking to my GP, I was changed to Citalopram. One dose had me in panic mode. I tried Nytol for a couple of nights, but after reading all these reviews, I am going back on Mirtazapine tonight. Maybe 7.5mg only because it makes me have awful dreams. The biggest problem with this wonder drug for me is constipation. I can overcome that with CosmoCol powders. I feel I should write a review to help others. I am 85 and reasonably fit. Good luck all you fellow sufferers."

• Anonymous
• April 15, 2012

Remeron (mirtazapine) "I've been on Remeron for nearly two weeks now, and I can feel my mood elevating and depression decreasing already. Also, I'm now getting full nights of sleep, which is also an amazing feeling. The only downsides I've seen so far are some grogginess in the morning (though that has been less and less noticeable) and ravenous hunger (this has not gotten less). Luckily, because now I'm starting to actually want to leave the house and do stuff, I've been able to work out pretty consistently this past week, and hopefully that will counteract the effects of me eating the weight of a horse every day. I've tried more antidepressants than I can count on one hand, and this is the first time in a long time I've started to feel better."

• Lena
• Taken for 1 to 6 months
• March 16, 2023

"I am taking 15 mg each night as a sleep aid and an accessory drug to SSRI. Before I started taking it, I read all the negative opinions online and I panicked. After a few days of taking it, I almost stopped due to its overwhelming effect of extreme tiredness and feeling like I could sleep for 12 hours a day and still be sleepy the day after. But I decided to still give it a try - and I don't regret it. I feel like this drug is a miracle for me: it calms my anxiety in the evening, and evenings were the worst part of my day (my psychiatrist told me it's unusual for patients with depression, as they tend to find it difficult to get up. I always found the evenings way worse). It enables me to get decent sleep at night. You know, don't believe everything you read on the internet. Maybe this drug will work for you, maybe it won't. Maybe it will meet your expectations, so just give it a try, wait 2 weeks and see."

• mfsjhc
• Taken for 6 months to 1 year
• December 30, 2014

"This has seriously been my miracle. After trying 5 different SSRIs with horrible side effects, Remeron literally saved my life. I was given it during a hospital stay (I was suicidal). The only side effects I've experienced were sleepiness (in the first few weeks) and increased appetite (ongoing). Personally, my depression caused me to have no appetite at all, so the increased appetite was a welcome effect, although it may not be for others. I can sleep, I can eat, and - most importantly - I can live. I can get out of bed in the morning and live my life. I am on 45 mg once a day (at night). With this medication, in combination with CBT and mindfulness meditation, my depression is almost completely gone."

• FLGAL
• Taken for 1 to 6 months
• March 24, 2017

Remeron (mirtazapine) "This medication was the magic bullet for me anxiety wise and depression wise. I slept extremely well and my anxiety plummeted. I would have definitely stayed on it if it weren't for the atrocious weight gain! I am normally 110 lbs or so, and within 1.5 months was up to 130lbs! During this time I wasn't eating much more than normal and I was skateboarding, canoeing, and running yet still putting on weight. I was the happiest, yet the fattest I had EVER been on this drug, so it was love/hate relationship. I decided to go off of it because I couldn't tolerate the weight. Was a shame, since it was extremely effective for me otherwise. Oh well."

• Ayds
• February 25, 2016

"This medication worked within 2 or 3 days and now I am back to my normal, happy self. My depression journey: Depression started to show itself during year 9 of high school, and continued to get worse until I finally reached 20 years old and decided it was time to get help. I started seeing a doctor who prescribed SSRI sertraline, then went on to see a psychologist, and finally a psychiatrist. During this time, I went through ZOLOFT 200mg, Celexa, Cymbalta, and while Zoloft 'helped' a little, it wasn't until I tried Mirtazapine (Avanza, Remeron) 15mg that I finally had a restful sleep, my appetite came back, and my smile returned, my self-esteem improved, and I suddenly realized I was back to normal. And my libido returned! Keep going, never give up!"

• Lexilou
• Taken for 1 to 6 months
• May 30, 2019

"My husband was put on this mirtazapine after suffering from depression/anxiety he was also on citalopram 40mg. He took mirtazapine at night and within 2 week I noticed a massive difference for the worst. He changed completely into a monster he was unbearable to be around he was snappy, arrogant, kept in silence trances for days, nasty and rude, he even ended our marriage, I contacted his GP and he was taken off them immediately and I'm happy to say he is a lot better. He has just been told he may have some brain damage due to lack of oxygen when his lung collapsed so he has been on a lot of different tabs but mirtazapine I think done more harm than good. Anyone else have this?"

• debbie...
• Taken for 2 to 5 years
• July 25, 2013

Remeron (mirtazapine) "It's helped me with sleep and a bit with my depression. Over the years, they have upped my dose to 45 milligrams. It hasn't helped me a bit with my anxiety. Actually, if you wake up at night, your body is asleep and your mind is active, which makes it hard to walk. This has just started happening to me, so I think I may need to increase to 60 milligrams. I believe 60 is the max. Wondering if I'm building up a tolerance to it. I have been taking this medication for 4 plus years. I was also told that it was an appetite stimulant and it didn't do anything for me there either. This medication did not mess with my head or make me feel groggy in the morning. I would give this medication a chance before all other antidepressants."

• garre...
• Taken for 1 to 6 months
• March 25, 2014

"I was seriously depressed! Thought I would never be the same. Remeron has been a lifesaver! It took 2 weeks before I started to feel the effects and at 5 weeks I feel like my old self. Side effects for me were sleepiness in the first week and has not been bad since. A few headaches and a lot of eating, but I need the weight anyways. Don't let the weight side effects keep you from trying Remeron. They will subside. Give this medicine a try. Well worth it."