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Mirtazapine for Depression User Reviews (Page 2)

Brand names: Remeron, Remeron SolTab

Mirtazapine has an average rating of 6.7 out of 10 from a total of 613 reviews for the treatment of Depression. 53% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Mirtazapine

  • marcy
  • April 4, 2015

Remeron (mirtazapine) "I've been taking this medication for approximately 3 years now. For all who are upset with the weight gain and sleepiness, it doesn't last forever. I think I gained about 10-15 lbs in my first few months, but I've managed to lose it all. Now I am only sleepy right after I take it (at bedtime) and I wake up feeling rested without the hangover. It's definitely levelled off my depression, and I feel normal. If you can get past the first few weeks, this medication is a life saver. I truly forgot that this medication even has side effects, since I've been on it so long. Also, I tried the SSRI/SNRI route first. On Zoloft, I would've made a great cast member for the Walking Dead. I've never felt more like a zombie. Remeron is the best!"

9 / 10
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  • Ann
  • Taken for 6 months to 1 year
  • May 8, 2024

"I got this medication for my anxiety, depression, and sleep issues. I was previously on Zoloft, which gave me horrible side effects and at no dose helped my anxiety or depression. When I was put on mirtazapine, I had no side effects except a little more tired in the morning. I started with 15mg, and it helped with my depression and a little bit with anxiety. Then I was put on 30mg. At this dose, my depression got so much better. This medication was very life-changing for me. My anxiety also became way more manageable, and I could finally live a life without almost constant physical anxiety symptoms. This medication also helped me so much with sleep. I fall asleep faster, and I barely wake up at night."

10 / 10
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  • laes
  • Taken for 1 to 6 months
  • June 19, 2023

"Mirtazapine almost killed me. I was severely depressed and put on a low dose to help me to sleep. It did not sedate me at all but made me dangerously suicidal. I tried to take my life repeatedly. The doctor said the low dose was the issue so he upped it which did not make a difference, except that I put on 2 stone in weight. I was on it for 3 months and then refused to take it anymore. I came off it 3 weeks ago. Suicidal thoughts have gone, I have lost half a stone in weight and feel so much better. Nobody warned me that I could become dangerously suicidal and my life was put at risk. I will never take antidepressants again. Be very careful when taking this stuff, make sure you know all of the risks!"

1 / 10
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Frequently asked questions

  • Gemma
  • Taken for 1 to 2 years
  • August 3, 2021

"This drug destroyed my life. It completely altered my brain and turned me into a raging monster. I have no more empathy or sympathy for humans. I can no longer feel joy or love. My brain burns and I have massive flu like symptoms. I vomit all the time now because this stuff ruined my stomach lining. I have diarrhea very bad as well. I am allergic to foods and smells now. I have akathisia which is the worst pain on this planet. My brain is damaged! I cannot even believe this garbage is legal. It's worse than street drugs! It completely altered my personality! Words will never describe what I have had to endure for years because of this crap! YEARS!"

1 / 10
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  • Anony...
  • Taken for 1 to 6 months
  • August 12, 2019

Remeron (mirtazapine) "I was started on 7.5 mg of Remeron when I was having anxiety and panic attacks. Within a few days, I started feeling significantly better. A few months later, and I have had only a few minor episodes of panic. It has greatly improved my life with no major side effects."

9 / 10
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Are you taking this medicine?

  • Anonymous
  • Taken for 2 to 5 years
  • June 1, 2019

Remeron (mirtazapine) "I've been on Remeron for several years now. Primarily for insomnia but also for anxiety and depression. This medication helps me tremendously like no others I've tried. No side effects besides hunger and weight gain. Highly recommend"

10 / 10
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106 Report
  • HERE
  • Taken for 1 to 6 months
  • October 7, 2020

Remeron (mirtazapine) "REMERON/MIRTAZAPINE was wonderful the first two weeks particulary because I felt dismal for 50 years then mirtazapine came about. But after two weeks of a new life of positivity things changed to a life of pain nausea apathy crying worrying close to zero motivation even to use the restroom. I can go on and on , basically now I wonder why people live for 100% negativity literally even when you list all things. I wish I never experienced the good from this drug because now mental torture and horrible chronic pains would best describe my life!!!"

1 / 10
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  • 172cup
  • May 8, 2023

Remeron (mirtazapine) "I was on Remeron for 2 years, but over that time, I just got worse. I tried coming off three times, but the withdrawal was hell on earth! Luckily, but not lucky, I had a near-fatal car crash. I was in a coma in ICU for a month, then in the trauma ward for another at Southmead Bristol. For some reason, they took me off Remeron when I first went in. Eventually, when I came around six weeks later, after the delirium had gone, I felt better than I had for the last two years while being on Remeron. Even with a broken tibia, broken hip, broken jaw, damaged vertebrae, blood clots, and 2 cardiac arrests, it was worth it just to get off that poison!"

1 / 10
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  • lobo
  • Taken for 1 to 6 months
  • October 15, 2023

Remeron (mirtazapine) "I had tried Lexipro (sexual side effects) and Trintellex (worked a little for a while but eventually had no benefits). I also tried Trazodone which addressed the sleep a small amount but not enough to improve my overall mental health. A psychiatrist told me Remeron is known to address depression, sleep, and appetite. He was right. It improved all three. The only side effects were weight gain (which I actually wanted) and crazy dreams. I thought the dreams would subside after taking it for a while but they never really did. They aren’t nightmares, just very odd dreams. I was started on 7.5 mg. After about five months, I’m still on 7.5 mg. I definitely recommend it for sleep, depression, and lack of appetite."

10 / 10
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  • Kessie
  • June 2, 2020

"Took for about a month, starting on 15 mg a day. Never been so tired in my life. Went up to 30 mg because the tiredness is supposed to ease then. It did slightly but after a few days my skin was like sandpaper and eyes constantly watering, and both very sore. Didn't really feel better at all mentally, actually worse because I felt I had dropped about 50 IQ points and not able to think clearly to find solutions to problems. Felt despairing, too despairing to demonstrably show anger but there all the time in my mind, along with the worst depression ever. I needed to find something that I know I have to live with for the rest of my life. Took hours to wake up, a few hours where I would be sort of functioning, then go to bed very early, not just because of exhaustion but also because I couldn't do anything anyway because of constantly wiping my eyes."

1 / 10
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  • Neo
  • July 23, 2019

"I suffer from severe depression and anxiety. I would cry randomly at home, work, in public. I couldn't be around large crowds, I would have panic attacks. Self-isolated and constantly had suicidal thoughts. My MD started me on Wellbutrin and I reached the max dose of 450 mg. It didn't help. After my second attempted suicide, my doctor prescribed me Mirtazapine 15 mg. It started working immediately. I take the pill every night. After my first dose, I woke up the next day super tired and lethargic. The second day, the lethargy was gone. By day 4, I felt like a new person. I started thinking more clearly and was able to manage my anxiety and depression. I still feel anxious and still have sad thoughts, but not to the point of feeling suicidal. I do have to work harder to keep my diabetes under control because of the increased appetite, but the benefits of the medication far outweigh the side effects. I know this medication affects everyone differently, but this drug literally saved my life."

9 / 10
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  • Anonymous
  • October 19, 2012

Remeron (mirtazapine) "I have been on Remeron for 3 years now and it's the best antidepressant I've ever been on. I have tried Prozac, Celexa, Wellbutrin, and Effexor. Remeron is the only one that made me happy to be alive. I did gain about 3 pounds but then was feeling so good I decided to become a vegan and improve my physical health, which before I could have cared less about. So now I've lost the pounds. Plus, a few pounds is definitely worth the improvement in mood and sleep. I have found it's really important how much I take and at what time. I did get restless leg syndrome which made it hard to sleep so I tried breaking up my 30 mg pill and taking 1/2 at 7:30 and 1/2 at 9:00 pm. That wasn't helping my mood. For best results, I take 30 mg at 6:00 pm and go to bed at 9:00."

10 / 10
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175 Report
  • Anonymous
  • February 21, 2012

Remeron (mirtazapine) "I have been on Remeron for a little over 3 months for depression and anxiety. It has changed my life after years of insomnia and depression. I think I finally found what works for me. The first couple of weeks are rough though, I felt tired all the time, especially the first day; I slept 21 hours! It gets better after about 3 weeks. I am depression-free, and I sleep a whole lot better than I used to. If you are afraid of the side effects, don't worry, they will diminish after about a couple of weeks... just stick it out, it's well worth it. I have taken almost every antidepressant in the books, and Remeron is the only one that has worked for me. I think you should give it a try; it works for a lot of people!"

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  • K_Todd
  • September 12, 2009

Remeron (mirtazapine) "This antidepressant has been a blessing in my life. I was 25 lbs underweight due to depression, and also had sporadic sleeping. The side effects are a benefit for me. It makes you hungry, especially after you take it at night. I crave lots of carbs, and have been eating like I have never before. I have gained 11 lbs in just 1 month on Remeron. It also has a nice sedation effect to help with sleep. When I take my 30mg dose at night, I have everything ready because after 45 minutes I can barely keep my eyes open, and then get a great night's sleep. Side effects are worse during the first week, and then everything balances out! If you suffer from sleep and/or eating, then Remeron could be the biggest blessing in your life also. It gave me hope."

10 / 10
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202 Report
  • Super...
  • Taken for 1 to 6 months
  • October 21, 2019

"I really don't know if this is working for me. I fall asleep easily but just feel lost in life. I feel like the world is against me, and I only want to wake up and be my old self. I used to be really funny and light up the room. Now I feel like I just don't fit in and awkward."

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  • Smoot...
  • January 5, 2015

Remeron (mirtazapine) "I didn't experience a crazy increase in appetite; however, I did gain motivation that I previously didn't have to go to the gym and lift weights, which helped me put my weight back on. Side effects for me included slight numbness of the tongue, and I feel like I mumble a lot because of that. Side effects do not bother me due to the fact that I feel so much better because of the medicine."

8 / 10
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129 Report
  • Tiem
  • Taken for 1 to 6 months
  • April 30, 2019

Remeron (mirtazapine) "Started taking Remeron 3 months ago. I have severe anxiety and insomnia which in turn caused depression. I became dependent on Ativan after being hospitalized. I took the Remeron while weaning off the Ativan. I never thought my body would recover. I suffered through the withdrawals and while waiting for the Remeron to kick in. It helped me sleep starting the first night. Ever since I’ve been sleeping an average of 9 hours a night, which I desperately needed. For my anxiety and depression, it was a gradual effect and took almost two months to work. I’m glad I stuck with it. Don’t get discouraged when starting this med. It takes time to work. I’m happy to say I’m no longer dependent on Ativan. I only take it as needed, which is rare. Remeron has helped me wean off the Ativan as well as being able to function daily without constantly being on the edge."

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  • hippy...
  • March 18, 2014

Remeron (mirtazapine) "After trying these for about 5 weeks, I had to go back to the doctor to change. I felt worse than I'd ever felt in my life. I was so angry all the time for no reason. I cried more than I did before taking medicines. For the first time ever, I was thinking about suicide. It also gave me a massive appetite and I gained about ten pounds, which I didn't need. So, these definitely do not work for me. Fingers crossed my new ones will."

1 / 10
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  • Trytr...
  • Taken for 2 to 5 years
  • May 18, 2020

Remeron (mirtazapine) "I was feeling very depressed 3 years ago and I've always suffered from anxiety, I tried other anti-depressants but the side affects were horrendous so I started on 15mg Mirtazapine, they started to work after a few days. I felt calm and my anxiety reduced hugely, I also slept very well. They will give you very vivid dreams, after a few weeks I started feeling anxious/agitated during the day so I popped another pill and that did the trick after an hour. The Doc upped my dose then to 30mg and they worked great at night. But I felt very anxious in the morning so the Doc very unusually apparently prescribed 15mg for the morning, that really did the trick. Fast forward 3 years, I'm still on the 45mg and they still help me sleep, my mood however is a little on the low side, anxiety is quite bad, in a nutshell they work less and less the longer you are on them, I'm now thinking of tapering off them and trying some talking therapy even if I am a little sceptical of the value of doing so."

9 / 10
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  • Ashton
  • Taken for 1 to 2 years
  • July 11, 2019

Remeron (mirtazapine) "Terrible! Never again. I gained 13 pounds, and I'm normally a small person. You gain every few months. I felt like I was in a fog the whole time with no personality, and I didn't realize it until I got off. I refused to gain more weight and told them I'm getting off it. They told me to just stop taking it. DON'T! I did since they said to, and my anxiety spiked to a 10, and after a few weeks, I had a nervous breakdown. I also had insomnia for months and slept maybe 2-3 hours a night for the first two weeks until I said put me back on so I can wean myself off safely - the right way. It's been about 5 months off, and I still have insomnia, which could be lifelong. No one told me I would be addicted to this med."

1 / 10
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  • amore...
  • April 10, 2015

Remeron (mirtazapine) "Doctor prescribed me Remeron. I've been taking 15mg for about a month now. I've noticed an increase in hunger and I get great sleep with this medication. However, it hasn't helped with my anxiety attacks or depression. I also noticed that I'm becoming more and more forgetful, often find myself staring at nothing in a daze, and it's hard to articulate what I'm thinking or feeling."

5 / 10
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121 Report
  • -D-
  • May 25, 2016

Remeron (mirtazapine) "I have taken 15 mg Remeron for about 5 days so far and it already is a miracle pill for me. I am slightly underweight and had constant anxiety, but so far this medication has vastly improved my appetite and I just feel relaxed, but not in a drugged feeling way. I actually enjoy food and am no longer as picky of an eater as I was before, which is awesome. It also helps with sleep, as it certainly has a sedative effect after you take it. I was really groggy and tired the first day after I took it, but have been fine and energized every day since. I know every medication affects people differently, but if you are depressed and not worried about weight gain, give this a shot."

10 / 10
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  • depre...
  • Taken for less than 1 month
  • June 17, 2023

"The worst drug I have ever tried. Mirtazapine almost killed me, and I had to demand to stop this medication after three days. I have depression and anxiety and this made it so much worse. I felt like a literal zombie, I wasn't sure where I was at times. I binge ate as well and felt very sleepy all day. I had trouble doing my job. I would get strong suicidal thoughts that came in waves, so strong that if I continued this drug I would have worked past my survival instinct and ended it all. I know antidepressants work differently for everyone but this stuff is absolute junk! Suicidal thoughts aside, depressed people don't deserve a chemical lobotomy called mirtazapine."

1 / 10
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  • haley
  • April 18, 2012

Remeron (mirtazapine) "I have it all...anxiety, depression, and insomnia. Sometimes I can be anxious in the morning, depressed in the afternoon. I have tried Wellbutrin/Cymbalta combination, Pristiq, Viibryd, Effexor, and every SSRI. I definitely felt an improvement with Cymbalta/Wellbutin and Pristiq, but not 100% myself. Remeron has been a godsend to me. It works fast; dare I say I am in a good mood again after only three days. I was a bit tired in the morning, but I will gladly take some fatigue to get rid of the anxiety and depression, and I hear this goes away in time. As far as the weight gain, I have always been a good eater and go to the gym, so if my appetite increases (it hasn't as of yet), I will just have to monitor it. So far, it's been great."

10 / 10
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  • Anonymous
  • February 17, 2011

Remeron (mirtazapine) "Remeron is a unique medicine, since its side effects are sometimes as useful as its antidepressant effects. This medicine literally saved my life. For many years, I was around 90 pounds, and never slept. Now, I'm a healthy 120 and I sleep about 8 or 9 hours per night. It did take a long time to get to this point. When I first started taking it, I was tired all the time and very worried about the ravenous hunger! But now that I've been on it 2 years, I no longer gain weight, I'm no longer tearful and miserable, and I've honestly never been happier. God bless the people who made this drug. It literally saved my life."

10 / 10
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152 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.