Mirtazapine for Depression User Reviews (Page 3)

• Try...
• Taken for 2 to 5 years
• May 18, 2020

Mirtazapine "I was feeling very depressed three years ago, and I've always suffered from anxiety. I tried other antidepressants, but the side effects were horrendous, so I started on 15 mg Mirtazapine. They started to work after a few days. I felt calm, and my anxiety reduced hugely, I also slept very well. They will give you very vivid dreams. After a few weeks, I started feeling anxious/agitated during the day, so I popped another pill, and that did the trick after an hour. The doctor upped my dose then to 30 mg, and they worked great at night. However, I felt very anxious in the morning, so the doctor very unusually, apparently, prescribed 15 mg for the morning, that really did the trick. Fast forward three years, I'm still on the 45 mg, and they still help me sleep. My mood, however, is a little on the low side, anxiety is quite bad. In a nutshell, they work less and less the longer you are on them. I'm now thinking of tapering off them and trying some talking therapy, even if I am a little skeptical of the value of doing so."

• kay...
• March 17, 2009

Mirtazapine "Although I can't take tricyclics, I can take Remeron. I have treatment-resistant depression, and this is the only antidepressant I can tolerate (I have been on every type of antidepressant except Wellbutrin). I don't know why it works so well on me, but it saved my life. My weight had gotten down to 112 lbs (I'm 5'7) and I looked like a corpse. I've been on it for a good 8 years or so, and it still helps me sleep. The hunger side effect subsided for the most part, a good thing because I gained too much weight back at first, then leveled out at 130 lbs. Some of my family have tried it and it knocks them out for the night and the next day. Also, they've complained of a 'hangover feeling' after they wake up. Many doctors told me it's a good medicine."

• dep...
• Taken for less than 1 month
• June 17, 2023

"The worst drug I have ever tried. Mirtazapine almost killed me, and I had to demand to stop this medication after three days. I have depression and anxiety, and this made it so much worse. I felt like a literal zombie, I wasn't sure where I was at times. I binge-ate as well and felt very sleepy all day. I had trouble doing my job. I would get strong suicidal thoughts that came in waves, so strong that if I continued this drug, I would have worked past my survival instinct and ended it all. I know antidepressants work differently for everyone, but this stuff is absolute junk! Suicidal thoughts aside, depressed people don't deserve a chemical lobotomy called mirtazapine."

• Sle...
• Taken for 6 months to 1 year
• June 15, 2019

"1 year ago I was sleeping 2 hours a night and suicidal. I had panic attacks daily. The only medicine that seemed to work was Ativan, and I was terrified of becoming addicted. In October, I had a mental health crisis and my psychiatrist prescribed mirtazapine. It has changed my life. I can fall asleep immediately, my emotions feel stabilized, and I feel completely back to myself. I’ve had light weight gain (about 5-7 pounds) but to me, the weight gain is worth feeling like myself again. I never review things but this medication has been a lifesaver for me. I’ve been on it for about 8 months now and have no regrets. If you have anxiety and insomnia, and feel like you’ll be that way for the rest of your life, try this medication. It definitely doesn’t work for everyone (what antidepressant does?) but it’s the only one (I’ve tried Zoloft, Lexapro, and Trazodone) that’s worked for me."

• ixz...
• Taken for less than 1 month
• September 6, 2013

Mirtazapine "This medication has worked great for me. I was feeling pretty well with Prozac, but had to switch doses from 20mg to 40mg. The main reason I got off Prozac was because I had NO appetite and lost 17 lbs which, in my case, was a bad thing since I was already skinny and wanted to bulk up. I switched to Remeron, which not only made me feel better mood-wise, but increased my appetite and helped me sleep great! It's a 3-in-1 drug for me. It also helped a bit for my anxiety. Only have been taking it for about three weeks so I hope my mood, sleep, anxiety, and appetite stay this way."

• Ann...
• Taken for 6 months to 1 year
• May 8, 2024

"I got this medication for my anxiety, depression, and sleep issues. I was previously on Zoloft, which gave me horrible side effects and at no dose helped my anxiety or depression. When I was put on mirtazapine, I had no side effects except a little more tired in the morning. I started with 15mg, and it helped with my depression and a little bit with anxiety. Then I was put on 30mg. At this dose, my depression got so much better. This medication was very life-changing for me. My anxiety also became way more manageable, and I could finally live a life without almost constant physical anxiety symptoms. This medication also helped me so much with sleep. I fall asleep faster, and I barely wake up at night."

• Dea...
• Taken for 1 to 2 years
• September 12, 2016

Mirtazapine "After a year of taking this, I have trouble speaking at all, severe sedation, and constant irritability. Also, a dangerous lack of care about my personal affairs and suicidal ideation. I'm called 'stable' when really I'm frozen in depression. I will never trust a psychiatrist again."

• hip...
• March 18, 2014

Mirtazapine "After trying these for about 5 weeks, I had to go back to the doctor to change. I felt worse than I'd ever felt in my life. I was so angry all the time for no reason. I cried more than I did before taking medicines. For the first time ever, I was thinking about suicide. It also gave me a massive appetite and I gained about ten pounds, which I didn't need. So, these definitely do not work for me. Fingers crossed my new ones will."

• kar...
• December 6, 2011

Mirtazapine "The extreme sleepiness and lack of efficacy ceased like a light switch - suddenly, after a couple of weeks of sleepy torture that didn't help at all, it WORKED for my depression, and the sleepiness was GONE. I woke up one morning to find I could breathe without the feeling of having my lungs filled with tar (one symptom of my depression). I stayed on it for 2 years and it alleviated my depression continuously while allowing me to feel like 'myself.' However, it did make me hungry, and I gained about 15 lbs. Worth it. When life improved, I tapered off, and have been fine ever since. If you try it, give it a chance. My doctor said 60% of his patients report a 'light switch' experience with it."

• 515...
• Taken for 2 to 5 years
• October 13, 2019

"My experience only, mirtazapine is the best thing that has ever happened to me. I was anxious and depressed, but it just made me feel better overall. I was always feeling nauseous, and this took that away. I had lost 10-15 lbs because I never felt like eating. This medication brought me back to my initial weight, but it never made me fat! Looking at reviews, this medication gets a bad rap. I don’t know where I would be without it."

• Bet...
• Taken for less than 1 month
• August 2, 2013

Mirtazapine "I have been taking 30 mg 1/2 hour before bed for about a month. The first night I took it, I woke up in the middle of the night incredibly thirsty, went to get a drink, and lost all coordination. My husband found me lying on the floor, sweating profusely, burning with fever. He had to carry me to bed. By the time he decided to take me to the ER, I was cool as a cucumber and sleeping like a baby. I decided to stick with it and try again. (No luck with SSRIs for relief from moderate/severe depression & anxiety and insomnia.) I slept the entire next day, took the 30mg pill again, and had no similar episode. Very gradually, the sleepiness has waned along with symptoms. I am optimistic, though I do need to resist overeating, as I have gained 5 lbs."

• Hqu...
• Taken for 1 to 6 months
• August 27, 2024

"I’ve been on different SSRIs and Seroquel low dose for a decade. I had migraines, low libido, and convinced myself it was the price to pay for curing my social anxiety and depression. I was wrong. Mirtazapine is highly effective with zero side effects for me. When I first took it, I gave up on day 4 due to the drowsiness. I tried again a few weeks later and hung in there, and after 10 days, I woke up one day feeling very good and still do 3 months later at 15 mg. It helped me fall asleep the first 2 weeks, but not anymore. The drowsiness totally disappeared. I have hope for the future now as I can focus on my work and socialize. So my advice: hang in there, there’s a light at the end of the initial zombie tunnel."

• mun...
• Taken for less than 1 month
• August 8, 2014

Mirtazapine "I have several issues and was given Remeron along with Seroquel and Tegretol. I take it at night and I sleep now, it's pretty amazing, but I'm so tired after taking it that I can't keep my eyes open no matter what. In the 3 weeks I have been on it, I have gained 3 lbs, which is awesome for me. I hope the sleepiness dies down some as it is a bit strong for me, but overall this is a great medicine."

• ano...
• December 15, 2018

Mirtazapine "I had insomnia that had me sleeping max 4 hours a night for 8 months, so I was losing my mind. Mirtazapine improved my mood substantially, made me able to sleep, helped me function, and reduced the worst of my depression symptoms significantly. It also completely stopped my full-blown panic attacks - I have only ever experienced a much milder, limited symptom panic attack since having been put on it. Unfortunately, there is considerable weight gain and voracious appetite. I wasn't warned about this, so I went up 2-3 sizes within 2 months without realizing what was going on. I haven't been able to keep the weight off while on Remeron despite low-cal diets, etc. Keep an eye on your portions and calorie intake when starting this. I'd still rather be a couple sizes larger and no longer suicidal and able to sleep than skinny and unable to function!"

• ral...
• Taken for 1 to 6 months
• December 24, 2012

Mirtazapine "I started on Remeron 15mg per day. I started to feel somewhat better at two weeks. Went up to 30mg at that point. After being on 30mg for about a week, I felt significantly better. I've gained a few pounds, around 4, so that's not too bad. It did not help with sleep. I experienced insomnia for 3-4 days after starting or changing the dose. Also, had some difficulty with thinking clearly for a few days after changing the dosage. I have severe Major Depressive Disorder (MDD). I believe Remeron will really assist me. I feel like I'm on a good path. I particularly appreciate the absence of sexual side effects."

• Jay...
• June 4, 2019

"I have severe PTSD and depression. Started on 15 mg mirtazapine, worked up to 45 mg with 100 mg topiramate and 9 mg melatonin (oh, and please taper up on the topiramate if you will not remember how to get home, lol). Yesterday, I told myself that this is honestly the best I have ever felt. This is coming from a 100% service-connected combat veteran with over 15 psych ward admissions and 3 suicide attempts."

• Anonymous
• Taken for 1 to 2 years
• July 24, 2013

Mirtazapine "I have been on Remeron for a little over a year for depression, anxiety, and insomnia. It has helped quite a bit in all areas. I have had a bit of weight gain (approx 10 lbs) but it is starting to come off slowly. It is a small price to pay for feeling all around better, especially being able to get a decent night's rest."

• Mni...
• Taken for less than 1 month
• January 22, 2020

Mirtazapine "I was prescribed 7.5 mg Remeron along with 50 mg of Zoloft. I've only taken two doses, and it left me in a zombie state for two days. I slept, but I slept from 11 PM to 11 AM, which is obviously unrealistic. Even after I woke up, I felt out of it, as if I was on drugs almost, and was exhausted all day. I also felt like my thinking was off and like I couldn't even form a sentence, it is very terrifying. It is almost like my brain can't process what is going on in front of me, even my vision felt off. I don't plan on taking this anymore."

• Dra...
• Taken for 5 to 10 years
• November 3, 2019

"Have taken Mirtazapine for around nine years. I have taken all three different doses for lengthy periods, depending on the severity of my depression and anxiety. My advice would be to give it time if you find it's not helping. It won't be easy, but after four to six weeks on a new dose (adjusted according to how severe my symptoms are), the effects will become apparent. Trust me, I've been on this medication a long time. Yes, there are negative effects, i.e., weight gain, dry mouth, daytime lethargy. But it's a small price to pay for a sound mind. Plus, lifestyle choices can help reduce the negative side effects."

• Pop...
• Taken for 2 to 5 years
• April 25, 2015

Mirtazapine "The first time my doctor prescribed this medication, I ate 2 whole large pizzas, a family-sized lasagna, 2 sandwiches, and some desserts all in one sitting. The day after, I decided to get off of it. I then realized I couldn't sleep very well and I had some depression, which otherwise, at the time, nothing else was helping me cope with besides my Buspar/Klonopin. Thus, I continued my dosage of 15mg. It is true, at least for me, the lower dosage is higher sedating of the medication. Once I figured out a way of controlling the 1-2 hour boost of what seemed like an infinite metabolism, I felt awesome, if only for a short while, then immediate beauty sleep followed. I definitely recommend this to anyone with sleep problems."

• sha...
• Taken for 1 to 6 months
• January 1, 2019

"Wow! It is a miracle pill for me. It took me out of a deep, dark hole. I took it for 3 months at a 15 mg dosage, then 7.5 mg for a few weeks, and that's it. It helped me a lot to come back on track. I had major depression, and because of that, I was not able to sleep full nights. I was very much sleep-deprived, which increased my depression too much. I was going through a super bad phase. My nights passed tossing and turning in bed. Mirtazapine helped me a lot in sleeping, which slowly cured my depression. Remember, guys, better sleep helps in curing depression. I recommend giving it a try for a few months, starting at a low dosage. Thanks. Bless you all, dear brothers and sisters."

• sca...
• August 1, 2013

Mirtazapine "I have been prescribed Remeron for about 8 months now and it is a miracle. It not only helped me put on weight when I needed to because I have lost so much from all the anxiety, it also gave me an amazing night's sleep every night. Yeah, it does give you some crazy dreams sometimes and you might gain a few pounds, but your quality of life is so much better. I was so happy the next day when I woke up. I finally felt like I figured it out. I say yes to the Remeron Cycle."

• DDa...
• April 18, 2017

Mirtazapine "I have tried Doxepin, Escitalopram, and others. Remeron or Mirtazapine is the best for chronic insomnia with depression (my issue). It also reduces daytime anxiety. I feel relaxed but sufficiently alert for mental and physical work. I think my efficiency has increased with it. So far no weight issues either (I think not all people will gain weight, probably only a small minority), stomach feels great. No dry mouth, no anticholinergic side-effects. Even my allergies are dying. Hamstring pain is also reduced, which I suffer from, and somehow one of my painful cysts has also disappeared. All in all, my daytime posture is better than ever since the age of 18. I feel youthful. The only negative side effect I feel is increased urination."

• hel...
• Taken for 1 to 2 years
• May 13, 2021

"This medication has helped me tremendously. Though I had to find out the hard way from the previous medication, which I tried for at least 4+ weeks to give it a chance, but got extremely worse quite quickly. Very bad thoughts that I wasn't experiencing before made everything I was trying to fix worse and more. I know people on the other med that swear by it, so it just proves how hard it is to find the right one for each individual. This is definitely the right one for me and also helps with sleep."

• Anonymous
• Taken for 1 to 6 months
• May 30, 2023

"I was prescribed 15 mg/day for depression with insomnia. While my sleep improved, I became very irritable and quick to anger. I had no patience. In addition, in only 4 weeks on this drug at what I was told was a low dose, I gained 10 pounds. I had terrible cravings, particularly for sweet foods, which is not typical for me. Even with regular exercise, I could not avoid the extra pounds. I am coming off the mirtazapine."