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Mirtazapine for Depression User Reviews (Page 3)

Brand names: Remeron, Remeron SolTab

Mirtazapine has an average rating of 6.7 out of 10 from a total of 613 reviews for the treatment of Depression. 53% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Mirtazapine

  • Dead...
  • Taken for 1 to 2 years
  • September 12, 2016

Remeron (mirtazapine) "After a year of taking this, I have trouble speaking at all, severe sedation, and constant irritability. Also, a dangerous lack of care about my personal affairs and suicidal ideation. I'm called 'stable' when really I'm frozen in depression. I will never trust a psychiatrist again."

2 / 10
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101 Report
  • Wayne...
  • Taken for 1 to 6 months
  • September 25, 2018

"I was put on mirtazapine 15 mg after trying citalopram and also sertraline for depression. Mirtazapine has saved me from committing suicide. The first couple of days were rough where I felt awful and sluggish, but then those side effects just disappeared, and now I feel great in the day and have enough energy for anything I want to do. It's been a godsend for me, and I hope somebody out there will read this and ask their doctor for it because honestly I just wanted to die, and now I'm getting back to being my old self."

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80 Report
  • Mnich
  • Taken for less than 1 month
  • January 22, 2020

Remeron (mirtazapine) "I was prescribed 7.5 mg remeron along with 50mg of zoloft. I've only taken two doses and it left me in a zombie state for two days. I slept but I slept from 11 pm to 11 am which is obviously unrealistic. Even after I woke up I felt OUT OF IT, as if I was on drugs almost and was exhausted all day. I also felt like my thinking was off and like I couldn't even form a sentence, it is very terrifying. It is almost like my brain can't process what is going on in front of me, even my vision felt off.I don't plan on taking this anymore."

4 / 10
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Frequently asked questions

  • Speced
  • Taken for less than 1 month
  • July 14, 2019

Remeron (mirtazapine) "After taking this one week I have to say I am totally sedated. If we had an earthquake ( CA) I wouldn’t be able to get off the bed. I am quitting now. I am a fall risk, new widow, and anxious. I feel like this drug is changing my heart rate and have horrible headache. Almost ER time. Please tell me someone, how long is this in my system ?. I am worried I’ll be in bed all day. Literally can’t stand up and this after 12 hrs sleep"

1 / 10
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70 Report
  • ixzla...
  • Taken for less than 1 month
  • September 6, 2013

Remeron (mirtazapine) "This medication has worked great for me. I was feeling pretty well with Prozac, but had to switch doses from 20mg to 40mg. The main reason I got off Prozac was because I had NO appetite and lost 17 lbs which, in my case, was a bad thing since I was already skinny and wanted to bulk up. I switched to Remeron, which not only made me feel better mood-wise, but increased my appetite and helped me sleep great! It's a 3-in-1 drug for me. It also helped a bit for my anxiety. Only have been taking it for about three weeks so I hope my mood, sleep, anxiety, and appetite stay this way."

9 / 10
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Are you taking this medicine?

  • Sleep...
  • Taken for 6 months to 1 year
  • June 15, 2019

"1 year ago I was sleeping 2 hours a night and suicidal. I had panic attacks daily. The only medicine that seemed to work was Ativan, and I was terrified of becoming addicted. In October, I had a mental health crisis and my psychiatrist prescribed mirtazapine. It has changed my life. I can fall asleep immediately, my emotions feel stabilized, and I feel completely back to myself. I’ve had light weight gain (about 5-7 pounds) but to me, the weight gain is worth feeling like myself again. I never review things but this medication has been a lifesaver for me. I’ve been on it for about 8 months now and have no regrets. If you have anxiety and insomnia, and feel like you’ll be that way for the rest of your life, try this medication. It definitely doesn’t work for everyone (what antidepressant does?) but it’s the only one (I’ve tried Zoloft, Lexapro, and Trazodone) that’s worked for me."

10 / 10
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  • Mickey...
  • April 11, 2015

"Two years ago, I returned to the UK after living in Spain for 11 years. I lost a retail business, a 6-bedroom villa, and a 21-year marriage all in 8 months. I returned to the UK homeless and penniless. Since returning, I have had no will to try again and fell into a downward spiral of depression where I really didn't care whether I lived or died. I tried every drug you could name, but nothing worked to make me feel any better. Mirtazapine has totally transformed my life. I am now back in the gym, feeling confident again, and wanting to kick life back in the arse. At 57, I have never felt better. I keep fit, liquify fresh fruit and veg, and take turmeric, green tea, and pomegranate concentrate. The whole combo works great for me."

10 / 10
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108 Report
  • muninn
  • Taken for less than 1 month
  • August 8, 2014

Remeron (mirtazapine) "I have several issues and was given Remeron along with Seroquel and Tegretol. I take it at night and I sleep now, it's pretty amazing, but I'm so tired after taking it that I can't keep my eyes open no matter what. In the 3 weeks I have been on it, I have gained 3 lbs, which is awesome for me. I hope the sleepiness dies down some as it is a bit strong for me, but overall this is a great medicine."

7 / 10
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  • kaylynn
  • March 17, 2009

Remeron (mirtazapine) "Although I can't take tricyclics, I can take Remeron. I have treatment-resistant depression, and this is the only antidepressant I can tolerate (I have been on every type of antidepressant except Wellbutrin). I don't know why it works so well on me, but it saved my life. My weight had gotten down to 112 lbs (I'm 5'7) and I looked like a corpse. I've been on it for a good 8 years or so, and it still helps me sleep. The hunger side effect subsided for the most part, a good thing because I gained too much weight back at first, then leveled out at 130 lbs. Some of my family have tried it and it knocks them out for the night and the next day. Also, they've complained of a 'hangover feeling' after they wake up. Many doctors told me it's a good medicine."

10 / 10
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  • ralphs
  • Taken for 1 to 6 months
  • December 24, 2012

Remeron (mirtazapine) "I started on Remeron 15mg per day. I started to feel somewhat better at two weeks. Went up to 30mg at that point. After being on 30mg for about a week, I felt significantly better. I've gained a few pounds, around 4, so that's not too bad. It did not help with sleep. I experienced insomnia for 3-4 days after starting or changing the dose. Also, had some difficulty with thinking clearly for a few days after changing the dosage. I have severe Major Depressive Disorder (MDD). I believe Remeron will really assist me. I feel like I'm on a good path. I particularly appreciate the absence of sexual side effects."

8 / 10
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126 Report
  • 5150
  • Taken for 2 to 5 years
  • October 13, 2019

"My experience only, mirtazapine best thing that has ever happened to me, I was anxious, depressed just made me feel better overall. I was always feeling nauseous and this took that away. I had lost 10-15 lbs because I never felt like eating. This med brought me back to my initial weight but never made me fat! Looking at reviews this med gets a bad rap. Don’t know where I would be without it"

10 / 10
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  • Betty...
  • Taken for less than 1 month
  • August 2, 2013

Remeron (mirtazapine) "I have been taking 30 mg 1/2 hour before bed for about a month. The first night I took it, I woke up in the middle of the night incredibly thirsty, went to get a drink, and lost all coordination. My husband found me lying on the floor, sweating profusely, burning with fever. He had to carry me to bed. By the time he decided to take me to the ER, I was cool as a cucumber and sleeping like a baby. I decided to stick with it and try again. (No luck with SSRIs for relief from moderate/severe depression & anxiety and insomnia.) I slept the entire next day, took the 30mg pill again, and had no similar episode. Very gradually, the sleepiness has waned along with symptoms. I am optimistic, though I do need to resist overeating, as I have gained 5 lbs."

8 / 10
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  • help
  • Taken for 1 to 2 years
  • May 13, 2021

"This medication as helped me tremendously. Though I had to find out the hard way from the previous medication which I tried for at least 4+ weeks to give it a chance but got extremely worse quite quickly. Very bad thoughts that I wasn't experiencing before...made everything I was trying to fix worse and more. I know people on the other med that swear by it so it just proves how hard it is to find the right one for each individual. This is definitely the right one for me and also helps with sleep"

10 / 10
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  • mquincy
  • Taken for 2 to 5 years
  • December 19, 2012

Remeron (mirtazapine) "Mirtazapine has helped me on more than one occasion. I've cycled through the gamut of antidepressants including but not limited to Prozac, Zoloft, Paxil, etc., but nothing really worked until Remeron. Thought I was okay to stop all medicines a year ago and did fine for a while but now feeling awful again; depressed and underweight. Renewed my script today and taking my first dose of Remeron tonight. Bring on the munchies! I just love a donut."

9 / 10
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  • Anonymous
  • Taken for 10 years or more
  • April 18, 2024

"I’ve had a tough life from birth on. At 17, I finally found out what had been holding me back. Diagnosed with Klinefelter's Syndrome. Was suicidal from the age of 8 on. It got much worse after the diagnosis. Life just sucked! Depressed, high anxiety, social phobia, severe insomnia, and had a death wish until my shrink prescribed Mirtazapine. I’ve been taking it for 25 plus years with no major side effects. I sleep soundly for 8 hours, zero anxiety, and life is worth living. It saved me from suicide. Now I only use it for sleep. It is difficult to wean off of, but if you are like me, there isn’t a need to wean down. If it works, let it work. I take 45mg at night. It does have a more sedating effect on lower doses, but my happy place is at the max dose of 45mg. Most drugs stop working after a period of time. Mirtazapine never fails at what it was made to do!"

10 / 10
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  • Pops
  • Taken for 2 to 5 years
  • April 25, 2015

Remeron (mirtazapine) "The first time my doctor prescribed this medication, I ate 2 whole large pizzas, a family-sized lasagna, 2 sandwiches, and some desserts all in one sitting. The day after, I decided to get off of it. I then realized I couldn't sleep very well and I had some depression, which otherwise, at the time, nothing else was helping me cope with besides my Buspar/Klonopin. Thus, I continued my dosage of 15mg. It is true, at least for me, the lower dosage is higher sedating of the medication. Once I figured out a way of controlling the 1-2 hour boost of what seemed like an infinite metabolism, I felt awesome, if only for a short while, then immediate beauty sleep followed. I definitely recommend this to anyone with sleep problems."

9 / 10
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102 Report
  • RHamms
  • Taken for 6 months to 1 year
  • November 6, 2019

Remeron (mirtazapine) "I have been on 15mg Remeron for almost a year & it has been a blessing. I suffer from chronic PTSD, Depression, Anxiety, & Insomnia. My anxiety was probably least affected by the medication, but it could be due to my dose. But my depression is almost entirely gone, if it does appear the duration is typically shorter & it’s overall less intense. I get a great nights sleep almost every night which is so important for health. My frequency of night terrors has been reduced to one per season, I don’t feel as dissociated, & when I get sleep paralysis (follows my night terrors) the duration is more like 1-2 minutes vs 30 minutes, which is just about how long it used to last. So far, Remeron is doing more than I could ask for regarding my mental health. Overall I’ve felt so much better & my brain doesn’t feel off or hazy or confused. I would recommend bringing it up to your doctor if you suffer from several mental health disorders like mine because it works well for that combination."

8 / 10
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  • kargi...
  • December 6, 2011

Remeron (mirtazapine) "The extreme sleepiness and lack of efficacy ceased like a light switch - suddenly, after a couple of weeks of sleepy torture that didn't help at all, it WORKED for my depression, and the sleepiness was GONE. I woke up one morning to find I could breathe without the feeling of having my lungs filled with tar (one symptom of my depression). I stayed on it for 2 years and it alleviated my depression continuously while allowing me to feel like 'myself.' However, it did make me hungry, and I gained about 15 lbs. Worth it. When life improved, I tapered off, and have been fine ever since. If you try it, give it a chance. My doctor said 60% of his patients report a 'light switch' experience with it."

10 / 10
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  • Anne
  • Taken for 1 to 6 months
  • October 16, 2013

Remeron (mirtazapine) "No effect on mood or anxiety, did help with sleep though. Gained 22 lbs over 3 or 4 months, which really made me depressed! Slowly tapered off on my own, am now losing the weight and just started Celexa. Can already feel a difference in anxiety level, am amazed."

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110 Report
  • Anonymous
  • Taken for 1 to 2 years
  • July 24, 2013

Remeron (mirtazapine) "I have been on Remeron for a little over a year for depression, anxiety, and insomnia. It has helped quite a bit in all areas. I have had a bit of weight gain (approx 10 lbs) but it is starting to come off slowly. It is a small price to pay for feeling all around better, especially being able to get a decent night's rest."

9 / 10
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  • anon
  • December 15, 2018

Remeron (mirtazapine) "I had insomnia that had me sleeping max 4 hours a night for 8 months, so I was losing my mind. Mirtazapine improved my mood substantially, made me able to sleep, helped me function, and reduced the worst of my depression symptoms significantly. It also completely stopped my full-blown panic attacks - I have only ever experienced a much milder, limited symptom panic attack since having been put on it. Unfortunately, there is considerable weight gain and voracious appetite. I wasn't warned about this, so I went up 2-3 sizes within 2 months without realizing what was going on. I haven't been able to keep the weight off while on Remeron despite low-cal diets, etc. Keep an eye on your portions and calorie intake when starting this. I'd still rather be a couple sizes larger and no longer suicidal and able to sleep than skinny and unable to function!"

8 / 10
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67 Report
  • Mirth...
  • Taken for 1 to 6 months
  • November 6, 2019

"Worst thing on the planet. It changes the structure of your brain both chemically and structurally. Do your research before going on this poison. It not only makes you a zombie it causes permanent brain damage. I was fully functioning with an advanced degree is psychology. Now I can barely leave my house and have severe difficulty with memory, cognition and memory. I am trying to wean off this stuff asap to see if I can salvage something of my former self."

1 / 10
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59 Report
  • DDarson
  • April 18, 2017

Remeron (mirtazapine) "I have tried Doxepin, Escitalopram, and others. Remeron or Mirtazapine is the best for chronic insomnia with depression (my issue). It also reduces daytime anxiety. I feel relaxed but sufficiently alert for mental and physical work. I think my efficiency has increased with it. So far no weight issues either (I think not all people will gain weight, probably only a small minority), stomach feels great. No dry mouth, no anticholinergic side-effects. Even my allergies are dying. Hamstring pain is also reduced, which I suffer from, and somehow one of my painful cysts has also disappeared. All in all, my daytime posture is better than ever since the age of 18. I feel youthful. The only negative side effect I feel is increased urination."

10 / 10
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  • Drax
  • Taken for 5 to 10 years
  • November 3, 2019

"Have taken Mirtazpine for around nine years. Have taken all three different doses for lengthy periods depending on the severity of my depression/anxiety. My advice would be to give it time if you find its not helping. It won't be easy but after four to six weeks on a new dose (adjusted according to how severe my symptoms are) the effects will become apparent. Trust me, I've been on this medication a long time. Yes there are negative effects, i.e weight gain, dry mouth, daytime lethargy. But it's a small price to pay for a sound mind. Plus lifestyle choices can help reduce the negative side effects."

9 / 10
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  • shabz
  • Taken for 1 to 6 months
  • January 1, 2019

"wow!!! it is a miracle pill for me. It took me out of a deep dark hole. I took it for 3 months at 15 mg dosage. Then 7.5 mg for few weeks and that's it. It helped me a lot to come back on track. I had a major depression and because of that I was not able to sleep full nights. I was very much sleep deprived which increased my depression too much. I was going through a super bad phase. My nights passed tossing and turning on bed. Mirtazipine helped me a lot in sleeping, which slowly slowly cured my depression. Remember guys better sleep helps in curing depression. I recommend give it a try for few months starting at low dosage. Thanks. Bless u all dear brothers and sisters."

10 / 10
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65 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.