Caplyta for Bipolar Disorder User Reviews (Page 5)
Reviews for Caplyta
- jus...
- Taken for less than 1 month
- November 30, 2022
"I'm taking Caplyta for bipolar depression. I am 3 weeks in, and the side effects are kind of rough. Super dry mouth and nausea, constant yawning, and like a shaky feeling. I can tell it's working, but now I'm just noticing the side effects."
- ser...
- Taken for 1 to 6 months
- September 24, 2023
"I'm terrible at taking my medications regularly, Caplyta has been no exception. I take 1 at night and sleep like a baby for about 8 to 10 hours. I get no negative side effects at all. They are expensive, but if they work with no negative effects, to me that's priceless. I take it erratically, but it has boosted my mood a little, probably due to more sleep. It's also calmed me a little, I'm less moody, and have fewer mood swings. I'm slower to react, and I even think before I speak on occasion. The pills are easy to swallow, and it takes about 30 minutes to kick in."
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- Rai...
- Taken for 1 to 6 months
- August 23, 2022
"I have been taking Caplyta since April. I take it with Zoloft. I used to take Latuda before I switched to Caplyta because I kept gaining a lot of weight. On Latuda, I was always hungry. Now, on Caplyta, I almost never feel the need to eat. But I've noticed when I don't eat for several hours, I'm insanely irritable, and I get manic. That's when I realize that I am not only hungry, but starving. I just can't really tell when I'm hungry anymore. I just woke up out of a really deep sleep. I was almost paralyzed with exhaustion even though I got enough hours of sleep, and I was shaking all over, and my head is moving 100 miles a minute because I haven't eaten in over 12 hours. Is this normal?"
- Anonymous
- Taken for 1 to 2 years
- May 26, 2023
"Caplyta comes in 20 mg pills. I agree with all of the above reviews that my initial experience with the drug replicated the feeling of super icy or extremely hot sensitivity. I talked to my psychiatrist about this, and he recommended opening up the capsule and taking a micro dose of the pill on my tongue or putting it in applesauce. That cuts down on those side effects. It works really well as an anti-depressant for bipolar and is one of the few drugs on the market that does that. And just as a side note, if you have bipolar depression, you shouldn't be taking anything in the serotonin class because bipolar depression has nothing to do with dysregulation of serotonin. It will only make you more dysregulated over time. Caplyta is a D1, D2, and D4 antagonist, all of which have been shown to be implicated in bipolar depression."
- Hap...
- Taken for 6 months to 1 year
- January 22, 2023
"I suffer from depression, possibly unipolar, possibly (what my current psychiatrist thinks) bipolar II. I've been on Caplyta 42 mg for 11 months. The first few weeks, it seemed miraculous. I'd been suicidal due to lack of sleep; suddenly, I was sleeping 7-8 hours a night, and, what's more, in a good mood all day, even in the early mornings and the evenings. There was a bit of grogginess, but it wasn't bad. But gradually over the months, the side effects increased: the grogginess got worse, I seemed cold all the time, and I became easily confused in the evenings. And much of the positive effect on my mood went away; though my grogginess was greater-in fact, it was the worst grogginess I'd experienced in my life-I was sleeping less. Part of the worsening side effects may be a result of my deteriorating kidneys (I'm in stage 3 kidney disease). Now, at 11 months, the grogginess is slightly better, the chills are mostly gone, I'm sleeping 5-6 hours. My mood is usually good if I can wake up."
- Rd9...
- Taken for 1 to 6 months
- August 29, 2022
"I have been on Caplyta 42 mg for about 3 to 4 months. At first, the only side effect I had was when I woke up in the morning. I took it at night, I would feel extremely tired but couldn't nap. It did work for my hallucinations at first, but I always build a resistance to all of the antipsychotics that I've taken. So my hallucinations are back, but now are worse than before. I also noticed that I talk way more than I have in the past. I usually don't talk much. I'm gonna rate it higher than low because it does work, I just am resistant to treatment."
- Lor...
- Taken for 1 to 2 years
- January 5, 2025
"I've been taking this drug for a while now. It's been at least a couple of years now. And I've noticed it doesn't make me gain weight, which is a big plus for me and others as well who are having to use this prescription drug for whatever they are in need of it for. In my case, I'm bipolar 1. And what I was told by my Dr. is that I would have issues with going to the restroom, number 2, which I've had problems with before taking it. I found out that on my dad's side of the family, cancer runs in the bowels, and he had an issue there a while back. So this makes me very concerned about if I should even be taking this medication."
- Anonymous
- Taken for 1 to 6 months
- March 11, 2025
"First week: sleeping through the night, previous 2 years waking every hour, muscle soreness in the entire back-upper/lower, dizziness when sitting then standing, beginning to walk, swollen under eyes first 2 days after a night sleep, shortness of breath, extreme fatigue, body temperature changes."
- Jfh...
- Taken for less than 1 month
- December 25, 2023
"Within a couple of weeks of starting, my depression had gone from severe to moderate-severe. It was a noticeable improvement and was very welcome. I did not notice any side effects that I usually get with atypical antipsychotics. One of the few psych meds I've been on that I'd recommend!"
- Ano...
- Taken for less than 1 month
- July 30, 2025
"Starting on 42 mg. Day 3. Very tired all the time, but honestly it feels like it’s working for my bipolar 2. I’m not having too many side effects. TBD but after 11 drug trials, I’m hopeful that this will be the med that works for me."
- Kod...
- Taken for 1 to 6 months
- June 4, 2025
"I have bipolar 2, ADHD, PTSD, and anxiety disorder. I took Caplyta for 2 months. I didn’t gain any weight, which was great because I gain weight so easily and have with basically every bipolar med I’ve been on. It worked well for the 2 months, but my suicidal thoughts just got out of control, so I’m on lithium now. I didn’t experience any side effects, though! Not even a headache. I recommend this for sure. Get a manufacturer coupon! I got it for free!"
- Ano...
- Taken for 2 to 5 years
- August 28, 2025
"Caplyta has been the perfect medication for my bipolar 2. I usually tend towards more depressive episodes than mania, but I have been taking Caplyta since 2021 and haven't had a single episode either way. This is a wonderful medication for people with bipolar 2, and bonus: no weight gain!"
- Anonymous
- Taken for less than 1 month
- February 9, 2022
"I started this for bipolar 1 on 2/5/22. At first, I couldn't sleep. Day 4 was much better. I feel more like my old self now. I have had no side effects, and maybe won't have any."
- Cap...
- March 10, 2022
"Horrible! Can’t wait for the effects to go away."
- Yol...
- Taken for 1 to 6 months
- August 8, 2024
"My experience has been good. I am very stable, and I don't have any weight gain or sedation."
- blu...
- Taken for 1 to 6 months
- July 7, 2024
"Excellent medication. I tried antidepressants all throughout the nineties up until now. They never really worked for me. Caplyta helps with my hyperactivity, anxiety, and depression symptoms."
- lex...
- Taken for less than 1 month
- May 23, 2022
"Absolutely horrible. I threw up, my hands and feet started swelling up and felt like they were on fire, I had a fever of 100, and I went in and out of consciousness."
- tra...
- Taken for 1 to 6 months
- May 26, 2024
"This medicine is the best bipolar medicine I've been on. Taking this medicine has leveled me out. Other medications would have me so agitated. I love this medicine."
- Bip...
- Taken for less than 1 month
- January 29, 2022
"Has anyone taken this for bipolar? Thinking about giving it a try."
- Anonymous
- Taken for less than 1 month
- April 16, 2022
"First day on Caplyta. Little to no side effects compared to half a dozen others I’ve tried. So far, so good."
- Lis...
- Taken for 1 to 6 months
- May 30, 2023
"Made me more depressed, very tired, and unfocused. Not a good combo for a person with bipolar and ADHD. I tried it for a month before giving up."
- Anonymous
- Taken for less than 1 month
- September 18, 2022
"Make me feel super tired and hungover the next day, terrible headache, and body temp fluctuations."
- God...
- Taken for less than 1 month
- October 23, 2023
"Switched from Abilify to Caplyta and so far it's been a miracle drug. I've lost 11 pounds in a little over 2 weeks with no side effects to speak of. I'm excited to see its full potential soon."
- Jay...
- Taken for 1 to 6 months
- July 7, 2023
"Help my depression go away and stay away, overall no side effects, seems to have helped me tremendously!!!"
See also:
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"After having horrible nausea with lithium, my doctor switched me to Caplyta. I felt my highs and lows to be less dramatic. My biggest issue was the extremely dry mouth, but besides that for me, I didn't have huge issues with the other known side effects."