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Xyzal User Reviews & Ratings (Page 5)

Xyzal has an average rating of 5.4 out of 10 from a total of 285 reviews on Drugs.com. 41% of reviewers reported a positive experience, while 43% reported a negative experience.

Reviews for Xyzal

Commonly mentioned side effects
  • Fla...
  • Taken for less than 1 month
  • June 25, 2017

For Allergies "This medicine has severe side effects; that is, it causes irritability and tiredness. It does dry a person out, but the side effects necessitate cautionary awareness if you are going to drive or work with people. You have no patience. I do not recommend this product."

5 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 26, 2017

For Allergies "I feel absolutely horrible. I ran out of Zyrtec, my son takes this, so I figured I'd try it. On day two, I feel a combination of having a concussion and a hangover all at one time. I'm fatigued, dizzy, and have a headache. This does not include the pressure I feel in my sinuses. I feel absolutely horrible. I'm done, I won't take this again. I'm honestly not even sure the FDA should have approved this drug."

1 / 10
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19 Report
  • Ray...
  • June 4, 2017

For Allergies "Found this medication to be completely ineffective in treating my allergy symptoms. Not only was I up urinating many times during the night, but when I got out of bed, my eyes were tearing, my sinuses were swollen, and I was very drowsy. I believe this drug to be just another heavily promoted batch of promises that simply does not deliver. And yes, this stuff is not inexpensive to say the least. Save your money and just buy the home brand of antihistamine."

1 / 10
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16 Report

Frequently asked questions

  • jou...
  • April 2, 2009

For Allergic Rhinitis "I have been taking Xyzal for nearly 1 year now, and it truly has been my lifesaver. I suffer from extreme seasonal allergies and indoor allergies with all the symptoms: itchy red eyes, itchy ears and feet, sneezing 5 times an hour, congested sinuses, headaches, congestion, hives, and frequent bloody noses. I tried over-the-counter and prescription drugs for nearly 10 years with no success. Xyzal has honestly relieved all my symptoms. I take my dose before bed because it does make me sleepy. I have no problems making it through my workday. I do have a little bit of a dry throat side effect, but that is nothing compared to the misery I was in before."

10 / 10
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31 Report
  • Dse...
  • September 7, 2017

For Allergic Rhinitis "Day 2, throat drainage is much better, although hasn't stopped completely. Congestion in my nose is better as well. No problems with feeling sleepy. Trying this to see if I can avoid deviated septum surgery after being on antibiotics for 3 months for severe sinus infection."

6 / 10
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15 Report

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  • Adi...
  • Taken for 1 to 6 months
  • July 3, 2018

For Urticaria "Xyzal is horrible. I’ve spent the last 4 years of my life suffering due to side effects of antihistamines. These drugs are all the same thing. They make you feel annoyed, depressed, anxious, exhausted, dizzy, and just like absolute garbage! I thought Xyzal, being the 'newer and better' drug it was marketed to be, would be the miracle to save my life. However, it wasn’t. This drug is just as bad as the rest, possibly even worse. Also, keep in mind that Xyzal is no different than Zyrtec. It’s literally just the left half of Zyrtec, the part of it that actually works. It’s the same drug. If Zyrtec sucks for you, Xyzal will too. Honestly, I’m gonna go back to Claritin. It doesn’t stop my hives completely, but I am at least not a psychotic, depressed maniac on it."

1 / 10
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  • Sot...
  • October 18, 2009

For Allergies "I have severe allergies indoors and out. I cough constantly due to post-nasal drip and an irritated throat. I took Xyzal, and within hours, the coughing stopped! I ran out of pills and took Allegra. The coughing came back the same day. The coughing doesn't go down well with everyone being fearful of the swine flu! I am so thankful to have found Xyzal."

10 / 10
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26 Report
  • Den...
  • May 21, 2008

For Allergic Rhinitis "I picked this drug up from a pharmacy in Europe and loved it! Of course here (in the USA) you need a Rx, but it's well worth it! Love it! Better than Allegra, Claritin, or anything else I've tried so far! And my allergies on a scale of 1 to 10 are a 12."

10 / 10
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27 Report
  • Sta...
  • Taken for less than 1 month
  • May 4, 2019

For Allergies "This was recommended to me by a friend who has great success with it. I took just 2 pills, one Wednesday night and one Thursday night before bed. Within 20 minutes of taking Xyzal, my skin got beet red and I developed a fever! The first night I slept weird, but I slept. My cough is about gone and just a little congested. The pill works for that. The 2nd night I slept right through the alarm until 11 am! Needless to say, I missed work. Now I am left with side effects of bloody diarrhea, hives, fever, lightheaded to about passing out. I did not take a 3rd dose last night and am hoping the rest passes out of my body quickly. I do not recommend."

1 / 10
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  • Idn...
  • September 6, 2018

For Allergies "The very first day I took this medicine, it felt like someone was squeezing my brain. I don't know if my sinuses were that bad or this medicine was a contributor. After reading these reviews, I would not buy or use this product again, and plus, it's way too expensive. I wish I could have given it a 0 rating because a 1 is way more than what they deserve!"

1 / 10
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  • hol...
  • September 26, 2017

For Allergies "The instructions say that you should take it at night as it can cause drowsiness; however, this medication kept me up all night! It also made me feel anxious and weird. And to top it all off, I am still suffering from allergies. Guess it's time to try something else."

2 / 10
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  • wol...
  • December 9, 2009

For Allergies "I started using this right after starting immune therapy for indoor and outdoor (perennial) allergies. I had been on Zyrtec, and the additional dose of allergens coming from the shots made me miserable with continual sinus mucus draining/blowing; I tried taking Benadryl (on top of the Zyrtec), but that put me to sleep. The Xyzal stopped the allergic reaction, so I'm on it now for the second month with no side effects, and very happy to have it."

9 / 10
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23 Report
  • Bet...
  • May 24, 2017

For Allergies "I have had the worst allergies on record this season. I have tried everything from Claritin to Zyrtec and everything in between. Nothing helped. My post-nasal drip was so bad I felt like I had bronchitis from all of the coughing. I even thought I was going to overdose on my albuterol inhaler because I used it so much because I could not breathe. A friend recommended Xyzal and brought it to my house one day. The symptoms did not go away all at once, but after 2 days on the pill, I feel so much better. I take it around 6 PM every day and I sleep well and wake up perfectly fine the next day. Xyzal has saved me. I hope it lasts and doesn't wear off like Claritin."

9 / 10
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15 Report
  • Tex...
  • Taken for less than 1 month
  • May 14, 2017

For Allergies "I took this pill at bedtime twice, and it kept me awake until after 2:00 a.m. I woke up with worse symptoms than I had before I took the pills. When I woke up, I was stuffed up, and I stayed that way all day long. I also had lots of coughing - unlike my normal cough that is due to post-nasal drip. I also have a bad sore throat. On both Saturday and today, I have tiredness, and I am unable to function. I will go back to my normal medicine in the morning. These pills were a waste of money."

1 / 10
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  • Anonymous
  • May 13, 2010

For Urticaria "I have suffered from hives for over 30 years. No medicine helped. I had them for 3 years straight, 24/7. My hives have come back about 4 different times, lasting up to a year. I have been on Xyzal for about 2 months. I take Benadryl, then an hour later I will take the Xyzal. I take Benadryl at bedtime. This is the first time in the 30 years that I feel they are under control. For anyone with chronic hives, it's worth a shot. I have no side effects as of yet. They do not make me tired either."

10 / 10
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23 Report
  • Anonymous
  • June 7, 2008

For Allergic Rhinitis "It is a very positive medication for severe allergies. I have tried everything OTC and prescription. This is the first that allows me to sleep, without getting up 5 or 6 times a night because of my nose."

8 / 10
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24 Report
  • Anonymous
  • December 18, 2021

For Allergic Rhinitis "I was a happy-go-lucky person, and nothing in the world had bothered me whatsoever. I was on Cetirizine, and it made me tired, so I started to take Xyzal. It worked well at first, then I noticed a change. I couldn’t sleep until about 2-3 in the morning. I was always irritated and paranoid about every little thing. One day, I had a complete anxiety and panic breakdown. I thought that it was something different, but after the reviews, I realized it was the allergy medication. It made me believe it was something else, and it wasn’t. I don’t recommend this medication at all."

1 / 10
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  • MLB...
  • June 25, 2009

For Urticaria "I have had chronic hives for a year and a half. It's awful. I have been taking Xyzal for almost a year now. Xyzal works to eliminate the itching and rashes, but it makes me very tired. If I take it during the day, I feel tired. If I take it before bed, I have difficulty waking up and getting started. It also makes me feel down, just not myself. I have not found anything better to help with my rash outbreaks, so I do continue to use it."

7 / 10
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  • Anonymous
  • May 28, 2009

For Allergies "I have a rare skin rash that appears only during the summer months. It is an immune system response to heat. Xyzal 10 mg reduces the rash by about 20%, but after about a month, an immunosuppressive reaction occurred. I started getting large, painful pimples in weird places like the forearm, hand, and neck. Had a similar reaction to Flonase a few years ago. The immune system can't fight the pimples, so they take over. Disappointing because this is the first oral drug to have an effect on the rash. Hay fever gone too."

6 / 10
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24 Report
  • nas...
  • October 24, 2008

For Allergic Rhinitis "I have had chronic allergies, and nothing has helped. It would be normal for me to go through a box of Kleenex in a week. The major frustration with my allergies was my itchy feet and ear canals. Although Xyzal is very expensive (my insurance doesn't cover it), it is worth not having the itchy feet and ears that no one thought about."

10 / 10
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23 Report
  • Vic...
  • February 19, 2009

For Allergic Rhinitis "I think this drug is probably the best thing for people with severe allergies. I tried everything before Xyzal, and I finally stumbled upon this through my doctor, and I am so happy I did. Now I can actually wake up and go through the day without sneezing, coughing, or getting a head cold."

9 / 10
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23 Report
  • Mon...
  • Taken for less than 1 month
  • July 24, 2021

For Allergic Rhinitis "This drug made me completely crazy. I started having bad anxiety, then anger and depression. Very bad depression. Horrible headache and fatigue. I lashed out at a coworker and got in trouble. What a disaster. Never again. Going back to Zyrtec."

1 / 10
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  • kim...
  • Taken for 1 to 6 months
  • January 26, 2024

For Allergic Rhinitis "I've tried lots of allergy meds: Allegra, Zyrtec, Benadryl... None have really worked quite as well as Xyzal for me. I'd say if you just want a cheap allergy med to relieve some short-term symptoms, stick to Zyrtec. But if you have year-round rhinitis, I'd say give Xyzal a go! The side effects of the stuff really aren't so bad for me anyway; it helps me a little to get settled down for bed, but it's not like being roofied or taking morphine like a lot of reviews have said, in my opinion. My father has taken it, though, and said he felt super exhausted, but he is easily affected by antihistamines. If you do get tired easily from antihistamines, maybe try other things first? If not, give this a shot; it really helps with all-day relief and keeping you asleep! I struggle to stay asleep and I always wake up in the middle of the night; this stuff works wonders. TL;DR, I'd recommend this to people with year-round allergies who aren't super affected by antihistamines and their side effects!"

9 / 10
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  • Zen...
  • Taken for less than 1 month
  • February 10, 2019

For Allergies "I took Xyzal last night for the first time. I have awoken with the left side of my nasal passages blocked and a headache that feels like a benzo hangover. If I'm going to feel this way the morning after, I better have had fun the night before. 1/10 I will never take this again even though it was free."

1 / 10
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14 Report
  • Anonymous
  • July 17, 2017

For Allergic Rhinitis "Took this at night while waiting on an Allegra order. It was not terribly effective on my indoor/outdoor allergies. I felt marginally less wheezy at night, but my nose was stuffed and eyes itchy the next morning. On top of that, it makes me sluggish and stupid for a solid 24 hours. Forget drinking on this pill; the alcohol will go straight to your head. Granted, the label says all of this, but these itty-bitty pills aren't effective enough to be worth it."

3 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.