Xyzal and Headaches: What Users Say

• K A...
• Taken for less than 1 month
• September 12, 2019

For Allergies "Took Xyzal for allergies, within 1 1/2 hours seeing spots in eyes, hard to breathe, heart racing, felt panicky and had a headache. Sneezing had stopped, but still had a runny nose. Made me feel crazy and exhausted. Scary!!"

• sad...
• Taken for less than 1 month
• June 8, 2019

For Allergies "I got insanely dizzy (where I couldn't walk in a straight line for much of the day), had horrible anxiety and depression, and couldn't sleep at night. I would wake up several times a night having intense panic attacks, and during the day would feel unreal (zombie-like and insane headaches). It did what it was supposed to and kept my rash under control, but was not really worth the side effects."

• Anonymous
• August 6, 2011

For Allergies "I had been taking Allegra and Nasonex for years, but still did not have good control over my allergies and asthma. I used Benadryl as needed when my two prescription medicines were not enough. The pulmonologist told me that Benadryl has an intense drying effect in your body and that it makes your mucus more viscous (thicker). Within 2 days of starting Xyzal (and stopping Benadryl), I definitely had thinned mucus and my skin was much less dry. My asthma was much better controlled and I had less sensitivity to environmental triggers. Unfortunately, I also started experiencing moderate-to-severe headaches along with a feeling of depression/anxiety. Without Xyzal, I get pneumonia, with it, I feel crazy. Works, but bad side effects."

• WIR...
• Taken for less than 1 month
• June 3, 2017

For Allergies "I wouldn't wish this on my worst enemy. Kept me up, maniacally freaking out, until 4 a.m. Followed by extreme nightmares and tossing and turning. My head felt like it was going to explode. I literally almost went to the hospital. Terrifying."

• Bac...
• Taken for less than 1 month
• September 9, 2019

For Allergies "Tried Xyzal for the first time last week. I noticed I was a little groggy, which I've come to expect from most antihistamines. After taking it for 4 days, I have become an absolute mess. Very irritable, moody, crying, and angry. Just generally feel like I'm losing my mind. My 5-year-old daughter had the same reaction. And it didn't even help with the sneezing, runny nose, or watery eyes. In fact, it's given me a headache on top of making me feel insane along with all the allergy symptoms. Back to Claritin for us."

• utg...
• Taken for less than 1 month
• October 28, 2017

For Allergies "The reviews are true!!! I normally take 12-hour Allegra-D (as needed). When I took this, I immediately felt worse, my nose wouldn't stop running, I got very hot (red), and I was coughing almost like it made it worse. I felt it kick in and got extremely heavy. My nose felt like I was at the bottom of a pool, swollen, my eyes were puffy, my vision was impaired, I had horrible nightmares, and I barely woke up when my alarm went off. I felt worse than when I went to bed!!! Fatigued all day, bloated, headaches, swollen nose, and massive sinus pressure when I looked down at work. It felt like my senses were numb and I wasn't human. Everything everyone listed negative is true. I will NEVER take it again, and I'm shocked it's still available OTC. Do NOT waste your money, it's total fraud."

• Anonymous
• Taken for less than 1 month
• June 26, 2017

For Allergies "I feel absolutely horrible. I ran out of Zyrtec, my son takes this, so I figured I'd try it. On day two, I feel a combination of having a concussion and a hangover all at one time. I'm fatigued, dizzy, and have a headache. This does not include the pressure I feel in my sinuses. I feel absolutely horrible. I'm done, I won't take this again. I'm honestly not even sure the FDA should have approved this drug."

• Mon...
• Taken for less than 1 month
• July 24, 2021

For Allergic Rhinitis "This drug made me completely crazy. I started having bad anxiety, then anger and depression. Very bad depression. Horrible headache and fatigue. I lashed out at a coworker and got in trouble. What a disaster. Never again. Going back to Zyrtec."

• Zen...
• Taken for less than 1 month
• February 10, 2019

For Allergies "I took Xyzal last night for the first time. I have awoken with the left side of my nasal passages blocked and a headache that feels like a benzo hangover. If I'm going to feel this way the morning after, I better have had fun the night before. 1/10 I will never take this again even though it was free."

• Reb...
• November 30, 2009

For Urticaria "Within two days of starting this drug, my delayed pressure urticaria (DPU) came under control. It controls it so far to about the 95% level. I had a couple of major flare-ups the first day I took it, but I suspect the levels had not built up in my blood yet. I have had one headache, but unknown if this drug caused it. My allergies are also under control. The urticaria still appears a little, but much less in size, scope, and no itching or raised welts. No feelings of tiredness for me, in fact, it kind of speeds me up. I'm amazed that a cousin of Zyrtec can do so much more. Zyrtec didn't touch the hives before, even when taking up to triple the normal daily dose. If you have hives, give it a try."

• Ari...
• May 1, 2017

For Allergic Rhinitis "OMG, worst ever. I stocked up using all of the $5.00 off coupons, and what a waste of money. I realize this year is a double dose of pollen, but this medicine didn't help. Gave me bad headaches, and I felt listless and tired."

• Cja...
• Taken for less than 1 month
• February 26, 2020

For Allergies "Seemed to work pretty decently for my allergies, but the sleepiness was too much to handle. I felt really weird and out of it on just half a pill. I had pretty bad headaches too."