Lupron Depot User Reviews & Ratings (Page 5)

• Anonymous
• March 6, 2010

For Endometriosis "At first, I really thought the Lupron treatments were worth it, but now that I have made a trip to the Emergency Room. Well, let's just say if you are going to go the route of Lupron, you better be single. This drug takes its toll on the family, not just you. Everyone goes through the mood swings, headaches, blood pressure scares, joint pain, feeling like you are going to pass out. So, no taking your kids to school or sporting events. No joining carpools. Don't get too far away from the restroom, urinating more often is not unusual. The things that are the easiest to handle are the hot flashes, night sweats, and chills."

• Jen...
• Taken for less than 1 month
• August 20, 2020

For Uterine Fibroids "This is user Jennybean from the review below (August 12, 2020). I could not log in with that username, so here's my update: I got my first injection on 08/14/20. Ultimately, I am getting the 3 month 11.25 MG Kit. So I assume I will get 2 more shots. I got the shot in my butt cheek and it did not hurt or flare up. The side effects for me so far: a couple of short-lived hot flashes here and there. Fatigue and my boobs are sore (like before a period and wearing a bra sucks as a result). These effects are medium-mild and are not overwhelming. I'd say the fatigue and breast tenderness are the most bothersome. I expect I will be adding to my list of side effects as we go on. The last thing I'll add is that my biggest fibroid is 7 cm and my uterus never shrunk after I had my preemie son at 28 weeks pregnant. So basically, I still look six months pregnant 6 years later. That's why I'm on this medicine. I need to shrink my uterus and fibroid in order to have a less invasive partial hysterectomy (leaving my ovaries)."

• Mis...
• July 24, 2009

For Endometriosis "I took my first injection 4 days ago, but had a migraine that night. Since then, I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well, but the crying is the worst so far."

• Mlh...
• Taken for 1 to 6 months
• March 24, 2022

For Uterine Fibroids "I wanted to share my story also for people who are considering trying this out. I had big fibroids and was scheduled for a laparoscopic hysterectomy. My doc put me on Lupron for 4 months before the hysterectomy. She felt it would help me in hopefully shrinking my fibroids down to help with surgery. She wanted me to take the 3-month dose. I am very scared of side effects and really don't like taking anything. I did my research and decided I only felt comfortable taking the once-a-month lower dose Lupron shot. I was afraid to even try that. I was on Lupron for 4 months and I did bleed for the first month on it, and then my bleeding and periods stopped after the first month. My only side effect was hot flashes! But as time went by, they seemed to get a little better and they calmed down some. It wasn't too bad, but definitely uncomfortable at times. That's all, though! So happy that I moved past my fear and tried it. It helped stop my periods and I was able to get the laparoscopic hysterectomy done."

• Han...
• Taken for 1 to 6 months
• July 25, 2019

For Uterine Fibroids "I’ve been on Lupron Depot for 4 months for heavy bleeding from a fibroid and extreme pain due to endometriosis. It has stopped my uterine heavy bleeding, and I have increased energy from not being anemic any longer. However, I have experienced hair loss, generalized whole body muscle pain and stiffness, as well as hot flashes, extreme jaw tension, teeth grinding at night, and occasional insomnia."

• Lal...
• November 5, 2018

For Endometriosis "I will say I virtually have no periods and have had maybe 3 endo pain days that don’t come close to what the pain used to be. NOW the side effects are horrid! BUT I’ll take the side effects over the pain in periods. My bones ache, not unbearable, but uncomfortable. The night sweats, bad but bearable. I’m tired lots, but I can function with some caffeinated tea & B12 for energy. Mood swings and little depression/anxiety. It’s not intense depression for me, like nothing that makes me want to harm myself, it’s just more of a dark cloud following you around. So if you have mental “instability” before taking the drugs, make sure you talk to your doctor. I did not lose hair, and my hair did NOT thin/fall out. I did not gain weight. The side effects still make the medicine worth taking because I have no pain or real periods. I get the shot every 3 months (I’m on 9 months) and take a pill that comes in the shot package. The pill is taken daily, shot is every 3 months for me. Good luck!"

• Swe...
• January 6, 2017

For Endometriosis "I was diagnosed with stage 1 endometriosis after I had a laparoscopy. My doctor suggested Lupron Depot for six months (2 shots). I have been on Lupron Depot for almost 3 months where it is time to get my second shot. I am almost sure I will not get the second shot. I am in worse pain than I was before the shot, and I have had NONSTOP bleeding. You are not supposed to be bleeding while on Lupron, especially for three months. I have an appointment with my doctor soon about my next step. The medicine is supposed to rid you of pain-but for me, it caused it to worsen. In regards to other side effects such as hot flashes, depression, mood swings, etc., I don't have any of that! Bottom line, I wish I never would have gotten this medicine."

• Anonymous
• Taken for less than 1 month
• October 20, 2012

For Endometriosis "I am only one week into the Lupron, and my pain has begun to not ease, but not be as sharp as it was at all times. I can finally breathe and think before the next stabbing pains begin. But about two days ago, I got mood swings. I seem insane, I'm fine, then I'm screaming. I'm only 17, and this is NOT what I need along with the disease. I hope it gets better, for I won't have any friends at the end of the six months."

• des...
• Taken for 1 to 2 years
• January 15, 2025

For Prostate Cancer "Disclosure: the patient is a health care professional in the field of dentistry. I am an eighty-eight-year-old man who has stage four metastatic prostate cancer (metastatic to bone and local lymph nodes). My oncologist prescribed Lupron Depot injection every three months (in office) and in conjunction with oral medications Abiraterone Acetate plus prednisone taken daily at home. I have not experienced any undesirable side effects (including pain) from the infusions of Lupron Depot. The infusions are injected into the butt muscle. My tumor status and body responses are monitored with clinical laboratory tests every three months at the office visits. So far, the tumor response has been better than anticipated, and there have been no adverse clinical side effects. My PSA was 17 at diagnosis, and it decreased to >0.07, and it has remained there."

• CDM...
• December 17, 2016

For Endometriosis "I suffer from terrible cramps and fibroids. I do take a low-dose birth control that sometimes barely helps my cramps. I was given the 1 dose a month, 6-month treatment after my GYNO could barely do a vaginal ultrasound for one of my visits, and I had been having a 'period' off and on for over 3 months. The fibroid was so large it obstructed the movement of the wand thingy. I've been on it for 5 months, the 1st month, I still got my awful period and spent my usual $50 on pads and Advil, just as heavy. But by the 2nd month, bye bye Aunt Flo, and it's been pretty okay except for the hot flashes, weight gain, tiredness, and the sore hips, soles, and ankles. The sore hips, soles, and ankles don't hit until the 4th month. The hot flashes just suck!"

• cra...
• June 10, 2015

For Endometriosis "I am very happy I went on Lupron Depot. I am on my 6th month of it, and although the symptoms of hot flashes, night sweats, moodiness, and some weight gain are not fun, it still is VERY worth it. I have been pain-free (when I was in debilitating pain before) and no period, which is nice. Hopefully, I'll be able to get pregnant soon too!"

• Ste...
• December 21, 2019

For Endometriosis "I have stage 4 endometriosis and adenomyosis. Had emergency surgery 3 years ago due to a large endometrioma causing a total blockage of my sigmoid colon. Everyone's reports on here about unbearable pain and severe bleeding-yup, same for me. I've been bleeding nonstop for over a year now. Received my first 1-month dose of Lupron on 11/22/19. The only side effect was a slight uptick in libido the first two weeks during the initial estrogen spike. The last week of the month, I got my period, but the bleeding and pain were much reduced from before. Noticed an improvement in pain during intercourse. I am on the add-back and have had no night sweats, hot flashes, or vaginal dryness. No impact on my mood that I could notice. Received my second dose, the 3-month long dose, yesterday (12/20/19). Can't comment yet on the experience, but I'm sure hoping to stop bleeding entirely and eliminate the pain."

• Kia...
• June 30, 2018

For Uterine Fibroids "My experience was horrible. My OB/GYN recommended Lupron for my fibroids. I have 1 large one the size of a grapefruit, 3 the size of tennis balls, and many pea-sized. Surgery was not an option. I get Lupron shots 1 time a month for 6 months. I had 13 acne cysts in total on my face that I had to have surgically removed (over time). I gained 30 pounds almost overnight, and it took me 3 years of intense dieting to get this weight off. My body thought I was going through menopause, so I had the hot flashes as well. I would not do it again. I spent a fortune only to find out after 6 months and all of this that the tumors were the same size. Years later, I am having health issues and wondering if related to Lupron usage."

• Alm...
• November 13, 2011

For Endometriosis "I have been receiving Lupron shots since August 2011. December will be shot number five. Within the first two weeks after receiving my first shot, I noticed a huge difference in pain. How awesome! I had been dealing with this pain since 2008. I had exploratory surgery and tried Chinese medicine along with acupuncture and found no relief. Lupron has been the first thing to help me be almost completely pain-free. Will post again after the 6th injection. I had one huge mood swing after my 1st shot and very little hot flashes. I am not craving chocolate as much but have found myself craving milk (I have always been a milk drinker)."

• Can...
• Taken for 1 to 6 months
• September 23, 2020

For Endometriosis "Lupron ruined my health. It made me depressed and have suicidal thoughts, which are not normal for me at all. I did not continue after month 4, and unfortunately, because I wanted to stop the medication, my doctor would not see me anymore. Please research the ingredients and side effects before you choose to take Lupron. My doctor told me specifically not to look up the side effects... Not wise!"

• Sic...
• Taken for 1 to 6 months
• September 24, 2020

For Uterine Fibroids "My experience with Lupron Depot has been challenging. I have side effects of memory loss, trouble breathing (did not have this before), heart palpitations just about every day (worst at night), nausea, extreme tiredness (daily). Periods had stopped before but started up when taking Lupron Depot (very light to spotting). I am in my second month of the 3-month injection, and I now have body aches and hot flashes every 15 minutes all day, which have subsided to every 30 minutes to an hour as I get close to wearing off. I will not know if the fibroid has shrunk until after the 3 months have passed. Not interested in sex, so do not want to be touched. Very sensitive since the shot and not having a taste for really anything. Feet swollen like Ms. Piggy. Would I get it again? Heck NO! I would stop eating red meat first and drink a healthy smoothie with raw veggies and fruit first."

• Anonymous
• March 18, 2010

For Endometriosis "I just had my 5th shot yesterday. The past few months have been painless in regard to side effects other than night sweats and mood swings. I have not gained any weight, and everything seems pretty normal. Once again, other than the mood swings. These are harsh, and sometimes I feel like another person has taken over my body and thoughts."

• Sha...
• Taken for 6 months to 1 year
• September 20, 2019

For Endometriosis "I had severe endometriosis. I had the kind of pain that makes you blackout. I would bleed all over my chair at work. I wear only black or navy pants. So far, I've taken 3 shots, and thankfully I am pain-free. I have no period. But the hot flashes are HORRIBLE. I'm always hot and tired. I don't remember the last time I had a good night's sleep. I've gone as far as putting ice packs on my bed so that I can sleep for a few hours. I've gained about 35 pounds in 9 months, my hair is thinning, I ache all over, my vision has decreased so much, I seem to forget everything if I don't write it down. I think I got the entire list of side effects, however, that pain before taking Lupron? No way! I literally shake when I think about it. I'll try to manage."

• Anonymous
• January 1, 2010

For Endometriosis "I did a 6-month treatment of Lupron, and it wasn't that bad. The first couple of months, I experienced migraines and hot flashes. For the remainder of the treatment, I continued to experience the hot flashes, but my mood swings became very uncomfortable for my family, friends, and me. I would one minute be calm and neutral...the next minute I would become mean and hateful. That was never how I was prior to the treatment. However, I completed my treatment in August 2009, and I haven't had any problems with my endometriosis at all. My doctor has now given me the option to either get pregnant or continue with birth control pills until I decide to become pregnant to maintain the endometriosis. I highly recommend this method if you can withstand the side effects."

• Anonymous
• January 22, 2009

For Endometriosis "I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say, overall the good outweighs the bad."

• End...
• August 26, 2015

For Endometriosis "Lupron is not for everyone! I must admit I was horrified to try it, but it came to a point I would rather die, so I had nothing to lose. In 2011 and 2012, both 9 months each. Then after treatment was birth control (Levora), high dose. Now, 2015, just started having severe pain uncontrolled by anything else, so started Lupron injection yesterday. This med made me forget I had the disease. I'm not saying there could be long-term issues or anything else. But right now, in this moment, I'm not sick, and every time before, it was a godsend. Hopeful this time will be as smooth as the last couple of times. Good luck."

• Doi...
• December 1, 2016

For Endometriosis "During my early 30s, I had 2 laparoscopies and 1 laparotomy for severe endometriosis but had no relief from pain. At 34, I had my 1st Lupron Depot shot. It eliminated my pain completely. The only side effects were hot flashes and irritability. The side effects were exactly what I am experiencing with menopause now at the age of 58. I did not have any joint pain or other side effects. After 6 months of shots, my primary care physician advised that bone loss could result from prolonged treatment, so we stopped treatment. As an alternative, I was put on low-dose birth control pills, which I took every day to stop my periods. Should have done this to begin with! No pain and no side effects!"

• Ei...
• December 7, 2016

For Endometriosis "I have endometriosis and adenomyosis, and pain was scary, and I became bedridden some of the days. I had my first Lupron 11.25 mg in June 2016. I am suffering following side effects, but I will continue this medication as pain from endo and adeno is worse than side effects. - Swelling at feet - Weight gain - 6 kg in 6 months - Increased sweating - Hot flash suffered only the first month of this treatment - Fluid retention - Carpal tunnel - Forgetful - Growth of upper lip hair - Slipped disc and compression of the right leg nerves. I am going to take the second injection soon, and after that, I will go for hysterectomy. Btw, I am just 36 :(."

• rub...
• Taken for 1 to 6 months
• July 11, 2018

For Uterine Fibroids "I had 8 tumors in my uterus, and the doctors told me there was no way to remove them. They gave me 2 shots of Lupron, and I started losing my memory, and the bleeding increased. I did a search for doctors that remove the tumors, and I found one. He took out the tumors, I was able to keep my uterus and have had no problems since. I thank God every day for this doctor! The only bad thing is, thanks to the drug, my memory is damaged for life."

• Anonymous
• November 8, 2009

For Endometriosis "I was very pleased with my Lupron experience. I was on a six-month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth months were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laparoscopy 2 months before the medication, and I started acupuncture treatments about a month before beginning Lupron, which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all."