Lupron Depot User Reviews & Ratings (Page 3)

• upt...
• December 4, 2017

For Uterine Fibroids "I was so skeptical about these shots, scared to death of the side effects after reading posts. I could kick myself! My shirts fall past my waist, I always looked pregnant. Slight headache, took generic aspirin, did the trick, hot flashes, weird but not that bad. Cycle, had one regular (heavy) period then skipped. Overall, I was so satisfied, I just called and ordered my second shot (I get them quarterly). Everyone reacts differently to different types of medication. What works for others may not work for you, but this did work for me. Good luck. Sorry for the grammar stuff, I was in a rush."

• Ang...
• Taken for 1 to 6 months
• February 28, 2018

For Endometriosis "I was diagnosed with stage 4 endometriosis in April of 2017. My situation was a little different because the disease went into my colon and shut down my bowel system. After two surgeries, my doctor recommended I go on Lupron for 6 months. After reading the reviews, I told my doctor no. I was scared out of my mind. He insisted and I finally agreed. I just took my last shot of my 6mo treatment, and in the beginning, I experienced the hot flashes, but I was given Northein pills to offset it, and it worked. I didn't bleed; I occasionally had sweats, nausea, or an upset stomach. However, I can't say anything really bad about the drug. I'm glad I took it. I think it depends on the individual body, but I will say you have to give your system time to adapt to the drug."

• Kat...
• Taken for 1 to 6 months
• October 4, 2019

For Uterine Fibroids "I had the Lupron shot on 1st July 2019 for fibroids. It was fine for the first 2 weeks. Just slight breast soreness and general signs like I was gonna get my period. After the first 2 weeks, I started getting hot flashes, fatigue, and memory loss. Had a lot of problems recalling thoughts. I never bled since I had the shot, which was weird. I thought I'd get one last major period or something. I had surgery to remove my fibroid in early September. The fibroid never shrank. Guess the jab didn't work on me. I'm still getting the hot flashes, and the body aches, as well as fatigue, has gotten worse. I also gained weight! I found the drug increased my appetite. I still haven't gotten my period yet. Kind of happy about that but worried my hormones are all messed up. For reference, I'm 40 years old."

• duc...
• Taken for 6 months to 1 year
• July 11, 2021

For Prostate Cancer "I have been on Lupron for 6 months (2 of the three-month injections). This drug is very effective in slowing the prostate cancer growth. Testosterone is the fuel for PC. My testosterone level went from 840 to 11 in three weeks after my first injection! However, there surely are side effects. Mine are: 1. Fatigue and low energy with breathlessness upon exercise. 2. Hot flashes. 3. Low red blood cell count (anemia). 4. Lack of sexual desire and unable to perform. 5. Shrunken testicles and penis. The side effects are frustrating...but you can tough them out. God has given me strength, and without my faith...this would be much tougher. My wife has been an angel with her constant support. Good luck!"

• Ema...
• August 11, 2013

For Uterine Fibroids "Received one shot for three full months. Nearing the end. Major side effects were the hot flashes and some weird feeling of uneasiness. I would not take it again. Hot flashes are not cool. Just had an ultrasound and will be seeing the doctor soon to see if the shot was a success in killing cysts. The drug may work, but wow, all these side effects."

• Mel...
• Taken for 1 to 6 months
• April 20, 2017

For Uterine Fibroids "Had a large pedunculated fibroid tumor on my uterus. The shot was administered, they found my fibroid got larger after 3 months. Had to have a partial hysterectomy to have it removed so I could sit, drive, and have sex without being uncomfortable or bleeding. I had every side effect, which was miserable. I had extreme hair loss (thinning), and I'm still trying to grow it back. This drug did not work for me. It has been over a year."

• Anonymous
• January 25, 2012

For Uterine Fibroids "I was bleeding 24/7 and anemic due to a large fibroid. First, I tried Depo Provera shots, which didn't work. All bleeding stopped about a week and a half after my first Lupron shot. At this point, it's only been a month, so I don't know if I'll still need a hysterectomy."

• alp...
• Taken for 6 months to 1 year
• August 21, 2018

For Uterine Fibroids "I am 28 with a 21 cm x 13 cm uterine fibroid. I was told my surgery would be risky and would leave me with a scar from under my chest to my pelvic area. Since I am only 28 and would like to have children of my own, they decided to put me on Lupron for 6 months to shrink the fibroid by hopefully 50% and have a much smaller and less risky surgery. Went on the shot in June, with the first month being the hardest, with headaches, night sweats, hot flashes, and my first period being very heavy with lots of clots. But I am on my second shot, 2.5 months in, and I can say most of those symptoms went away. I only get hot flashes, which are definitely bearable."

• lup...
• Taken for 1 to 6 months
• November 7, 2018

For Uterine Fibroids "I had very heavy periods. My doctor offered a Lupron shot. I decided to go with 2 Lupron shots hoping it would shrink my fibroid. Instead, my fibroid grew bigger. It caused me horrible headaches with the strongest painkillers not helping. After each shot, my period would not stop for a month (at least it was not heavy). Hot flushes were horrible. Good night's sleep was gone. I would wake up multiple times a night, all drenched in sweat. After the effect of Lupron wore out and my period restarted, it was as heavy as before. The only benefit I got was not having a period for a few months (with some bleeding in between), but at a very high price (side effects and actual price). I think, as heavy as my period was, it was better to have my period for a few days a month than have frequent very bad headaches and constant hot flashes. I would not recommend it based on my experience. I would not have it done if I had to decide today."

• cmf...
• Taken for 1 to 6 months
• August 19, 2015

For Uterine Fibroids "I had the 3-month 11.25 mg on 3/30/2015 to shrink my giant fibroid to the size that the laparoscopic myomectomy can be performed. I had no symptom of side effects for the first month and also had my period, but ever since the second month (May), the side effects have been really hitting me hard; including hot flashes and night sweats. I had my surgery at the end of June, and my doctor confirmed that I had reacted to the Lupron more than expected, as the fibroid not only shrank but part of it was degenerated. So, instead of a 2-hour operation, it ended up being a 6-hour one. Now, it's been 5 months, and the Lupron is still lasting (period still not back yet); don't know when it will be gone..."

• 23...
• Taken for 1 to 6 months
• November 18, 2013

For Endometriosis "I'm on day 48 of treatment and had my second shot on 11/04/2013. With the first shot, I bled 2 weeks prior and another 3 weeks after. After that, I haven't bled since. I'm being treated for lifelong (23 years) endometriosis. I have been disabled since 13 years old because of it. The only symptom I have had is severe non-stop hot flashes. I will have a hysterectomy in December."

• Ves...
• Taken for less than 1 month
• October 14, 2020

For Uterine Fibroids "I developed several fibroids in my late 40s that caused very heavy bleeding. I opted for a hysterectomy and was given one shot of Lupron about 3 months prior in the hope that it would shrink the fibroids before I had surgery. I cannot say that it shrunk them (my uterus size was comparable to a 5-month pregnancy), but it did stop my periods immediately and that made it worth it to me. The only side effect I ever experienced was extremely painful cramps a few times (once so bad I had to pull off the road because I was driving). Still worth it."

• Tee...
• Taken for 1 to 6 months
• February 10, 2020

For Endometriosis "The depo has been great for me! At the end of my 3-month shot, the only major side effect I have are the hot flashes (which are controllable). I haven’t had a period, haven’t been moody, minimal weight gain!"

• Cha...
• September 6, 2011

For Endometriosis "I LOVE LUPRON. I have stage 4 endometriosis, and Lupron has been AWESOME. I have only had one side effect: hot flashes, which I do not mind at all, they only come twice a day and last for up to 2 minutes. Hopefully, my husband and I can have intercourse without pain. I'm 23 years old."

• Ang...
• April 10, 2010

For Uterine Fibroids "I love that it completely stopped my outrageous heavy bleeding, which in turn made me anemic. So I am happy for that. However, the only side effect that I am experiencing is super dry skin on my arms, neck, and face... I feel it is aging me overnight. Some constipation, and not really hot flashes, but warm spells every now and then. Can't wait for surgery to get my hormones back to work."

• EJo...
• Taken for 2 to 5 years
• July 27, 2012

For Endometriosis "Six years ago, I experienced severe pain caused by an ovarian cyst and endometriosis. I eventually had my cyst removed, but after a few months, severe pain returned. I was dying of pain most of the time, until I could not tolerate it any longer. In August 2008, I was given Lupron Depot. The first month was a nightmare for me, I thought I was dying because of extreme bleeding. After that one month, my body slowly progressed. For three months, I had a 3.75 mg dose, and after that, I was on 11.25 mg. I am so relieved that it has allowed me to live a normal life. I am pain-free, and fortunately, the side effects were not too extreme. My last shot was in March, and I was supposed to have it last June, but due to the unavailability of my specialist, I am waiting for my next step. So far, I am doing fine."

• Anonymous
• Taken for 1 to 6 months
• April 24, 2015

For Endometriosis "I was diagnosed with Stage 4 endometriosis and had major surgery. I was only able to take four of the six shots. The side effects are terrible. I had almost all of them. I took my last shot in March 2015. It has been one month, and I am now experiencing panic and anxiety attacks along with high blood pressure. I am only 37 and gained weight, now weighing 155, and have a blood pressure of 142/103. I have never had high blood pressure until the third month of the shot. I have hot flashes, night sweats, chest pains that sent me to the ER, vaginal discharge, painful intercourse, vomiting the day I got the shot. It has been an awful experience. I am praying that when it gets all out of my system, I will not see any of these side effects anymore."

• Anonymous
• March 26, 2009

For Endometriosis "I am on my 2nd shot of Lupron, and I am not liking the new me. Everyone says after the first 6 weeks it gets better. I don't know if I can take anymore or if anyone else can take my mood swings. I am very hormonal, frustrated all the time, and mad about everything. My job and family are suffering. The hot flashes are constant, I am miserable. I don't think I will continue with the other shots."

• bar...
• October 30, 2013

For Endometriosis "Feb this year I had an ovarian cyst on my right ovary rupture, it was the size of my 3-year-old's head. When they operated, they found I was covered with endo... ah, finally a reason for my pain for the last 2 years... I have just finished my 6-month course. Endo pain fine, but OMG the side effects, dealt with hourly hot flushes home and at work.. gained 10 kgs (awesome), but the mood swings, REOW!! my poor partner. Lucky he is amazing... no pain yet, but have to wait and see what's next. Maybe Mirena."

• Lin...
• Taken for 1 to 6 months
• January 11, 2021

For Uterine Fibroids "This ruined my life! I don't recommend it. Get a surgery, and if you get pregnant, get a C-section. This drug (6 injections) was recommended by my doctor. The only choice he gave me, and he didn't tell me the lifetime side effects. There was just the 6 months suspension of periods (sweats, moods). In 2005, I was 32 years old, recently married, and we wanted to have children. Now, I'm 47 years old, we didn't have children anyway, and I don't lubricate, it hurts when I have sex, and my libido is gone, all this for the last 15 years, and I think for the rest of my life."

• sur...
• Taken for 1 to 2 years
• March 27, 2021

For Prostate Cancer "Had a prostatectomy in Oct. 2019, and PSA rose in April 2020. Took bicalutamide pills and a Lupron injection in Aug. 2020, second injection in Jan. 2021. The next injection is May 2021. My side effects are mostly really bad hot flashes day and night, extra fat around my waist, and got the mood thing going. My wife said I should talk to the doc before the next dose. I also got an inguinal hernia after surgery. It is a hard drug to live with, but at 71 years old, I'll take it every day. I see the doc next month for a checkup after a blood test. I also had 39 radiation visits in Jan. 2021. I hope my PSA is still around 0.034 due to Lupron. I have to take a total of 5 injections, which have been every 4 months. Good luck to people who have to take this route."

• Hop...
• Taken for 6 months to 1 year
• October 14, 2019

For Uterine Fibroids "I am 48 years old. I was bleeding nonstop for over a year due to a large fibroid...and I was in much pain. In January 2019, I started my Lupron 3-month shot, and I’ve had two more shots since then (every three months). I have not bled since January. My 6 cm centrally located fibroid shrunk to 5 cm within 6 months. My uterus reduced in size from 10 cm to 8 cm. I was anemic, but my blood levels are back to normal now. I do get hot flashes often. My hair is thinning and dry. My biggest problem is bone pain in my fingers/toes. But that’s nothing compared to how bad I felt when I was bleeding. I have been very moody at times over the past 10 months. I’m supposed to schedule one more dose of the shot before my doctor will decide what to do next, hoping I can just start menopause so I don’t have to have surgery. I also have multiple sclerosis. But so far the MS flare-up, due to this fibroid, is minimal."

• Ind...
• March 4, 2008

For Endometriosis "The shot is not too bad in the butt cheek. My problems were the side effects. I think that the hot flashes are the worst of it. I am on my 5th shot, and now I am going through a lot of mood swings as well."

• Ano...
• Taken for less than 1 month
• May 4, 2016

For Uterine Fibroids "Received a 3-month shot two weeks ago to stop heavy menstrual bleeding in preparation for a hysterectomy next month. My period started, and the bleeding is just as extreme as usual. No relief in blood or pain with this drug. Have experienced hot flashes (minor), headaches (minor), night sweats, nausea (moderate), and have pain in the upper right back area. Will be seeing the doctor later this week to get checked on. I know it's early in the process, but I'm disappointed. I took it knowing about the side effects, but was willing to go along with them to get my bleeding under control and to build up my iron stores."

• Mel...
• September 27, 2018

For Endometriosis "I had severe cervical dysplasia requiring a portion of my cervix to be removed, chronic pain, PCOS, and was diagnosed with severe endometriosis following laparoscopic removal of many adhesions from my uterus and scarring of my ovaries. My OB recommended I do six to nine months of Depot Lupron after my laparoscopy to keep the endo at bay and help reduce scarring. I started out with the one-month shot and felt okay, a little achy, and some hot flashes. I went back to get the three-month shot. I was miserable, but my OB really pushed me to keep going with it. I am on my second three-month shot, and I am not me anymore. I am moody, extremely depressed, my bones hurt, I've gained 20 lbs, I'm fatigued, anxious, have insomnia, headaches, and have had horrible gastrointestinal symptoms. It is ruining my marriage. My work performance has suffered. I am foggy and forgetful. Everything is an effort. I will not be getting the last shot and hope this hasn't caused irreversible damage!"