Skip to main content

Inclisiran and Headaches: What Users Say

Brand names: Leqvio

Headaches: mentioned by 6 users (6.3%)

Based on user experiences from 95 Inclisiran reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle pain 13.7%
pain 11.6%
joint pain 10.5%
burning 7.4%
cramps 6.3%
headaches 6.3%
fatigue 5.3%
rash 5.3%
stiffness 5.3%
itching 4.2%

Reviews for Inclisiran

Showing 6 reviews tagged with "headaches". Clear filters to view all 95 reviews.
Commonly mentioned side effects
  • K-T...
  • Taken for 1 to 6 months
  • August 15, 2024

Inclisiran for High Cholesterol "Just had 2nd injection…side effects abound (headache, nausea, muscle weakness and pain, low backache, constipation, ridiculous levels of fatigue, and much more) and never fully dissipated after 1st injection…fully started up again with this injection…all are annoying and affect quality of life…arthritis pain in hands and feet, and cramping in feet, legs, hands are among the worst along with the continual migraine. The medication definitely dramatically lowered my LDL…just not sure I want to continue."

9 / 10
Was this helpful?YesNo
38 Report
  • Nai...
  • Taken for 1 to 6 months
  • June 7, 2023

For High Cholesterol, Familial Heterozygous "I am experiencing severe muscle and joint pain, nausea, headache, sweating, palmar erythema, hives, the soles of my feet are burning hot, painful urination, and abdominal pain! Inclisiran damaged my liver! Are the side effects ever gonna go away? I was stupid to agree to have this poison. I'm really scared."

1 / 10
Was this helpful?YesNo
29 Report
  • cel...
  • Taken for 1 to 2 years
  • January 27, 2024

For High Cholesterol, Familial Heterozygous "I've had 3 injections, last one early December. Straight away, it floored me: headache, blurred vision, feeling weak all the time, muscle and joint pain, can't walk far, so much pain in hips, shivers, like I had influenza all the time. Quality of life-I was an energetic person. I had this injection. On a positive side, reduced cholesterol level in half. I'm due for another injection in June 24, not having it. My life has changed so much. I'll take my chances in exchange for the quality of life to return to what it was!"

6 / 10
Was this helpful?YesNo
7 Report

Frequently asked questions

  • fem...
  • Taken for less than 1 month
  • April 19, 2025

Inclisiran for High Cholesterol, Familial Heterozygous "First of all, I see a functional dietitian. Following a strict diet, regular exercise, and taking magnesium, vitamin D, vitamin K, I was able to drop 20 lbs in a year. My starting cholesterol was 315 and with a low-fat, no seed oil, higher protein diet, I was able to get my cholesterol down to 235. My LDL-C was 170. CA score of 165. So here I am, I had my first shot of Leqvio. Side effects are exhaustion, headaches, and foot and hand cramps. Extra water and magnesium seem to help."

5 / 10
Was this helpful?YesNo
0 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

Inclisiran for High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision, and sweating."

1 / 10
Was this helpful?YesNo
69 Report
  • San...
  • September 4, 2024

Inclisiran for High Cholesterol "Two weeks after the first injection, I developed pain in my hips, lower back, ankles, feet, hands, including toes and fingers, burning with urination, burning in my eyes, fatigue, and headaches."

2 / 10
Was this helpful?YesNo
14 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.