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Hyaluronidase and Nerve Damage: What Users Say

Brand names: Hylenex, Vitrase, Amphadase, Hydase

Nerve damage: mentioned by 5 users (6.7%)

Based on user experiences from 75 Hyaluronidase reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

burning 18.7%
skin issues 12.0%
dry eyes 10.7%
pain 9.3%
swelling 8.0%
nerve damage 6.7%
blurred vision 5.3%
bruising 5.3%
tight skin 5.3%
hair loss 4.0%

Reviews for Hyaluronidase

  • Ano...
  • Taken for less than 1 month
  • June 11, 2021

For Dissolution of Dermal Filler "I had Hyaluronidase injections used on my face to dissolve filler, and it has caused nerve damage, pain, and burning sensation. I experienced dry eyes, blurred vision, and it damaged my skin permanently. I have experienced volume loss, skin laxity, sunken eyes, changes in skin texture, and pain in the left side of my jaw. I am unable to open my mouth properly because my jaw clicks and locks. I had the injection over a year ago, never had any of these problems before, and it is still ongoing. It was an awful experience."

1 / 10
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136 Report
  • LAS...
  • Taken for 1 to 2 years
  • February 7, 2021

For Dissolution of Dermal Filler "I am permanently disfigured because of hyaluronidase aka Hylenex. It was unnecessarily injected into my lip damaging my nerve and destroying the area of my lips and chin, exposing my lower teeth. The enzyme spreads! It has been over a year and I still feel the stinging and burning everywhere the enzyme has spread to. Doctors lie and say this product will not damage you! No help for people damaged by this enzyme! How can the manufacturers of hyaluronidase create a product this dangerous without creating something to counteract its effects, should something go wrong? I have indentations in my face, and when I try to smile, my lower teeth are exposed, and my 'smile' is lopsided! I will never be able to smile again for the rest of my life!"

1 / 10
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97 Report
  • Too...
  • Taken for 6 months to 1 year
  • July 9, 2022

For Dissolution of Dermal Filler "Beyond devastated and hoping this was in my head like the doctors like to make you believe. I am destroyed. Sunken face, nerve damage, blurriness, burning… My relationships and job are downhill. Neck has aged over a decade-my cheeks dropped, and I had the best smile and best face and am honestly suicidal at this point. This is not a lie, people, we need to make something happen to get people to listen!"

1 / 10
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29 Report

Frequently asked questions

  • Tat...
  • Taken for 1 to 6 months
  • May 12, 2023

For Dissolution of Dermal Filler "I had hyaluronidase, and it’s completely taken my life for me. I am 26, I was a beauty therapist, had my own business, my own house, and a bright future. I was an attractive girl before all of this, now I don’t leave the house. I have nerve damage in my face and head, and all body skin laxity and muscle atrophy. My life has been ruined because of this drug. It’s literally poison, do not use it. We are not lying when we tell you all of the symptoms, I can promise you."

1 / 10
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20 Report
  • Ptt...
  • Taken for less than 1 month
  • June 6, 2022

For Dissolution of Dermal Filler "I was injected with 2 full undiluted syringes to dissolve undereye filler. The dermatologist explained to me she does this all the time with no issues. Needless to say, I was in the ER that week. The months following were horrific. Night sweats, hallucinations, gums receding and teeth numbness, nerve damage, constant blood in my nose, eyesight burning which spread from my undereyes all the way through my cheeks, then ears, then neck, then hands and legs, and what looks like feet at month 4-6. Fat became jellylike. At month 4, I had a reaction from something I ate, the whole inside of my nose and around burned and scabbed up. I'm 6 months in, and the systemic issues are out of this world. Constant infections, hair falling out, eyelash loss, cartilage changes in nose and ears, skin on the whole body is becoming loose. Joint pain, head pressure, etc., etc., etc."

1 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.