Skip to main content

Estrace Vaginal Cream User Reviews & Ratings (Page 2)

Estrace Vaginal Cream has an average rating of 6.3 out of 10 from a total of 73 reviews on Drugs.com. 53% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Estrace Vaginal Cream

  • Den
  • Taken for 2 to 5 years
  • April 3, 2018

For Atrophic Urethritis "I have been using Estrace for 5 yrs -a complete hysterectomy at age 42-can't live without it-no more nightmares, nerves are calm normallly according to my husband-HA! & don't have hot flashes. I am fortunate that my insurance has always covered It but in Jan 2018,a generic came out & my insurance would only pay for the generic. I was fine with that- but two months later I realized the generic was not working. All my symptoms had returned full blown! My husband told me to go to pharmacy and pay whatever the name brand Estrace costs! It would have been $325!! I told the Pharmacist my symptoms on the generic and he called my insurance company- told them I had had a reaction to generic-they then covered the name brand - within 24 hours I felt like a new person and better each day. I want to say here-the generic did not work for me. Keep working it women-there IS A way to have a GREAT AND HAPPY LIFE after menopause!"

10 / 10
Was this helpful?YesNo
64 Report
  • Anonymous
  • July 14, 2009

For Atrophic Vaginitis "I'm a 41-year-old woman who went into early menopause two years ago. Vaginal dryness and all the other wonderful symptoms of menopause are not something that I would like to deal with at my age, but sometimes we can't control. So, my doctor prescribed Estrace, and I use 1mg 2x a week. I was told that it would take about 6-8 weeks before seeing a difference. At the end of that time frame, I saw only a slight difference in vaginal dryness but many side effects. I had headaches, dizziness, bloating, and calf pain."

1 / 10
Was this helpful?YesNo
119 Report
  • Bewil...
  • Taken for 2 to 5 years
  • January 22, 2017

For Atrophic Vaginitis "I'm only giving Estrace Cream a 3 rating on the scale due to there being issues with the product. I have been using this product for a couple of years. It did help until the last few months, I went from using it 2-3 times a week to needing it every other day. My frustration comes from the amount that actually is in the tube. It says there is 42.5 grams in the tube, I alway keep track of the amount in the tube and end up with about 24 grams out of the tube in the end. Has anyone else kept track of this? Also, I can't afford it when I went yesterday to pick up a new tube and they wanted $290 for 1 tube?!! Why would it be this expensive? That was even after my insurance paid a portion."

3 / 10
Was this helpful?YesNo
70 Report

Frequently asked questions

  • bgkau...
  • Taken for 5 to 10 years
  • February 29, 2020

For Atrophic Vaginitis "The last 2 times when I used Estrace cream, I had bad burning and felt like I had a UTI. Out of desperation, I decided to try a vaginal yeast infection cream w/applicator to see if it made a difference. It did, both times!! Within hours, the symptoms decreased. By the next day, no further issues. Had no idea others had burning from the Estrace cream until I got on this site. May check out getting it compounded. I wonder why after years of using the Estrace (brand name), did this start all of the sudden. Have the ingredients changed??"

1 / 10
Was this helpful?YesNo
46 Report
  • Sharo...
  • Taken for 1 to 2 years
  • December 23, 2015

For Atrophic Vaginitis "Side effects of break through bleeding and little relief from thin tissue does not warrant the cost if over $300 with co-pay of $75. This is price gouging for a cream that should cost no more than $20 at the very most -- and I'm being generous. Over priced meds are out of control. I won't bother using Estrace anymore."

4 / 10
Was this helpful?YesNo
76 Report

Are you taking this medicine?

  • Sharo...
  • December 20, 2015

For Atrophic Vaginitis "Used as directed and not sure it did much, truthfully. I have been having bio-identical estrogen and testosterone implants and that does seem to be very effective. Also, OTC product called Luvena (Restorative Vaginal Moisturizer, pH balanced) is super effective and doesn't cause the stinging and break through bleeding of Estrace. Luvena is significantly cheaper than insanely over priced Estrace ($300 or a $72 co-pay). Really, Estrace should cost about $15 and not the criminally high price it is Bottom line: Not a fan of Estrace and certainly not worth the $72 co-pay for stinging and bleeding for me at ten years post menopause."

5 / 10
Was this helpful?YesNo
76 Report
  • grets
  • March 22, 2013

For Atrophic Vaginitis "Doc gave me samples of Estrace cream 2 weeks ago. I use 2 x per week for dryness and help restore thinning vaginal lining (prolapse problems). Noticed right away more hair loss the day after I use it. I was told this would not affect me in any way and only work locally in the vagina. I can't afford to lose more hair. I'm going to watch it and try a couple more times and if I notice hair loss continues I'll stop. I also use an all natural menopause cream (just started last month) has estrogen and progesterone from all natural sources. It seemed to be helping hair loss and all around symptoms. My first time on hormone treatment after my total hysterectomy seven years ago."

Was this helpful?YesNo
93 Report
  • Rachel
  • Taken for less than 1 month
  • April 19, 2018

For Atrophic Vaginitis "I’ve only been on estrace for a week, my symptoms? Hot flashes day and night, mood swings, I’d go up to the bedrooms and feel my heart palpitating, low energy, have a hard time getting up in the morning, no interest in anything. This cream is heaven sent, I’m looking forward to the next couple of weeks, have faith that it can only get better. I feel like a human being. I was honestly feeling like I was losing whom I am. I’ll keep you guys posted..."

9 / 10
Was this helpful?YesNo
58 Report
  • Mrs...
  • April 4, 2014

For Atrophic Vaginitis "My doctor gave me this cream for my vaginal dryness and pain and burning when I urinate. I'm 47 years old I don't have my period since this January, and started with the terrible dry vagina symptoms. I just started using the cream so far I haven't noticed the bad side effects yet and I hope I won't have it. I noticed when I urinate that the burning sensation is less. This morning when I woke up I feel my vagina less dry, but half of the day the dryness came back. I hope the more time I used the cream the symptoms of dry vagina go completely. I have avoided having sex with my husband because I'm afraid is going to hurt more. I'm very motivated reading the reviews I read before and maybe I can return to enjoy sex again."

5 / 10
Was this helpful?YesNo
82 Report
  • Tfruity
  • Taken for less than 1 month
  • August 6, 2017

For Atrophic Vaginitis "Painful sex for year and a half. Was at my wits end, finally went to the doctor and described severe pain and dryness not relieved. She prescribed this cream. Miracle drug! No more pain, dryness improving. My husband and I are thrilled! Go on their website for a coupon. Almost 300 bucks but I only had to pay $25.00"

Was this helpful?YesNo
60 Report
  • Anonymous
  • November 20, 2010

"I've been using Estrace 1 mg 2 times a week for around 9-10 years. It does help with the dryness, itching, and burning symptoms, but I've had two bladder infections. I can't help but wonder if having to REUSE the applicator (and maybe not being able to wash it properly or having leftover soap on it) is the cause. I hope to find a good source for disposable applicators so I can feel safer using this medicine."

7 / 10
Was this helpful?YesNo
99 Report
  • Miriam...
  • Taken for less than 1 month
  • January 26, 2016

For Atrophic Vaginitis "Extraordinarily overpriced since it is plant based - which means it is probably just soy. Even with my medicare drug insurance, it was going to be over $200. I called a Pharmacy where I used to get my compounded hormones - $27 plus shipping. Suggest you do too. "

7 / 10
Was this helpful?YesNo
68 Report
  • Folly
  • October 10, 2009

For Atrophic Vaginitis "I'm 57 and have been using Estrace cream sporadically for about a year. I've found the drug component to be pretty effective, but I just hate that greasy goop it's put in. I seems to leave a trail for days as it leaks out. I would prefer something that absorbs better."

5 / 10
Was this helpful?YesNo
94 Report
  • Patti...
  • October 25, 2016

For Atrophic Vaginitis "this past Feb I literally thought my insides were being ripped out. Expected to see them lying on the floor after sex one Monday afternoon.I was throbbing and hurting the rest of the evening and into the the morning.The next day I called my GYN and begged to be seen. she diagnosed my with this and several rips. She gave me an Estrace cream sample and prescription along with one for the rips. I do not have medical insurance.I healed the rips with coconut oil and started the cream 1 oz 2 times a week, She says it is not absorbed. Well, all I know is that my hot flashes have lessened, sex is no pain and if I don't use it like I'm supposed to, all that changes! I'm blessed to have friends in the medical field that can keep me in samples."

9 / 10
Was this helpful?YesNo
56 Report
  • bicyc...
  • October 7, 2011

For Hypoestrogenism "I am a 50 year old woman who started menopause around 37. I've been prescribed this cream and did well on it, but if I stop taking it, I tend to go back to having vaginal dryness. My main concern is that I've never been bigger than a size 8 and now I can hardly fit into a 10. I think it's caused weight gain and if I stop taking it, the weight does not go away. Has anyone else experienced this? "

5 / 10
Was this helpful?YesNo
82 Report
  • DeDe
  • April 23, 2016

For Atrophic Urethritis "I have been using Estrace cream for 11 years and it's been working. I use about 1/3 applicator every 5 or 6 days. Suddenly, it stopped working. I don't have a bladder infection, I already went through yeast infection treatment both Diflucan and vaginal creams, and my vagina still burns. The Estrace cream relieves it, but only for about 6 or 10 hours. I am 70 and not sexually active. I know years ago the urologist said everything look kind of shriveled up and dry down there. Could the hormone cream just not work anymore? Now what do I do?"

Was this helpful?YesNo
58 Report
  • Jill...
  • April 8, 2017

For Atrophic Urethritis "I have used Estrace samples for 6 months or so..... I ran out and went to buy another tube... 375.00!! And my insurance didn't cover any of it. (Costco was 325.00) I called my doctor and they gave me a coupon, but my insurance didn't work with it. So over priced... and my insurance just went up a 100 dollars a month... I just can't buy a medicine that is so over priced. I thought it would be 50 dollars or so... there must be something else we can use? Also, the information I read said: estrogens may increase the chances of getting cancer of the uterus. Why would we want to take this? I've got to do more homework and find something better!!"

1 / 10
Was this helpful?YesNo
52 Report
  • amysm
  • October 12, 2019

For Atrophic Urethritis "I used this once 3 weeks ago. Immediately had horrible burning and was up all night with what felt like a UTI. Am now on my 3rd antibiotic due to the inflammation and feel like these symptoms will never go away. It may be a Godsend for some, but if you are allergic, it is a nightmare."

1 / 10
Was this helpful?YesNo
37 Report
  • Notwr...
  • October 7, 2015

For Atrophic Vaginitis "I have been using 1mg every night for 12 days and am not sure if I can tolerate my side effect symptoms much longer to see if the cream actually works to diminish extremely painful intercourse due to dryness. I now have very tender breasts, a constant mild headache, and swelling, tenderness, and dryness of the external genitalia almost since the first day that I started using the cream. The only good effect so far is that my libido does seem to be heightened. So now I feel 'sexy' again but can't do anything about it because of all my discomfort! I plan on continuing using the cream at every third day intervals for 2 more weeks to see if my side effects subside. If I am still miserable, I will stop the medication and look for a non prescription vaginal moisturizer as my last hope for a continued sex life."

Was this helpful?YesNo
58 Report
  • Cassie
  • Taken for less than 1 month
  • September 14, 2019

For Atrophic Vaginitis "I tried 1 gram of Estrace 4 days in a row. I had extreme dryness prior to taking it. It corrected that, however I experienced itching, burning and several trips to the bathroom at night to urinate. I am through with it!"

3 / 10
Was this helpful?YesNo
36 Report
  • SheMac
  • August 9, 2015

For Atrophic Vaginitis "I have been using estrace vaginal cream for 8 weeks now, about 2 x a week and it has helped my vaginal dryness and prolapse but I am experiencing side effects, anxiety, bleeding gums, joint and muscle pain, problems with sleep. I don't like this. I am going to look for a more natural estrogen."

5 / 10
Was this helpful?YesNo
57 Report
  • Young...
  • Taken for 1 to 6 months
  • November 30, 2016

For Atrophic Vaginitis "I have suffered with endometriosis since I was 16 years of age... needless to say they did full histerectomy at 34 years of age, and still suffered painful sex after having my hormones shots each month , I was still having pain, ,, my doctor prescribed this cream and so far so good. Hopefully it continues to help me, this is embarrassing to women especially at this age. .."

7 / 10
Was this helpful?YesNo
47 Report
  • Lola
  • January 30, 2015

For Atrophic Vaginitis "USE IT OR LOOSE IT. Was prescribed Esctrace cream for dryness & painful sex. once a day for 2/weeks, then twice a week. 10 days and dramatic improvement. Here is the deal; waiting for 2 weeks before attempting sex. After 5 days I was able to do it with no problem. Not really enjoyable, but not painful at all. Best time was first in morning for a couple of minutes But if morning not an option, then a couple of minutes at night. but before inserting the cream so you don't accidentally take it all out."

8 / 10
Was this helpful?YesNo
55 Report
  • Anonymous
  • September 14, 2011

"I am 54 year old and postmenopausal, and have been using Estrace cream 1mg every night, for about a month for vaginal dryness. All of sudden I am experiencing itching and burning. I wonder I have an infection from this cream."

8 / 10
Was this helpful?YesNo
67 Report
  • I...
  • Taken for 2 to 5 years
  • March 19, 2016

For Atrophic Vaginitis "Someone replied to my first response that I need to wait 6 months. Well its been way over 2 years now, and I am still tearing and having that stinging feeling. I use 100% organic coconut oil for a lube, as my OBGYN said to try that too. I have no side effects from the coconut oil. I used both and then after "enduring" sex, I was left with a couple of tears that were bleeding and stinging. I am going to call her back and tell her I need extra strength. Even after the 1 mg amount, bathing the walls of my vagina, its still not enough. I am only 55, and did not think, this was going to be the end of me. My husband is 13 years older than me, and I am the one that has to turn him away because I am not healed enough to try again"

5 / 10
Was this helpful?YesNo
46 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.