Spravato User Reviews & Ratings (Page 3)

• for...
• Taken for less than 1 month
• February 20, 2022

For Major Depressive Disorder "For years (actually) decades, I’ve fought the beast… have tried it all and still fighting. I finally agreed to try Spravato. I thought it would be like a chemical ECT. I hesitate to say this and jinx the results, which have been stunning. I’m only in my third week of treatment, but the impact has been dramatic. Where I could barely get out of bed in the morning, I’m now up and moving. No negative side effects. No apparent issues with other meds I take. I only hope this impact will be long-lasting…"

• Chr...
• Taken for 1 to 6 months
• July 19, 2022

For Major Depressive Disorder "I have struggled with TRD most of my life. I did not respond well to other medications or therapies. My first treatment with Spravato at 56 was amazing. My second at 84 mg was intense, unpleasant, and also very beneficial in helping me address an issue. During treatment, my service dog died, and the grief was overwhelming. I went in crying and came out better able to cope. This is a game changer for me. The dissociative aspects help me to get out of my own way and address issues. I’m going to continue taking this weekly because each time it feels I’m dropping some sad, heavy weights and leaving them behind."

• Lal...
• September 2, 2020

For Depression "I suffer from depression. I’ve tried different meds, and none have seemed to help. I heard of Spravato and was very excited to know there was a treatment out there that could work. I’ve done 6 sessions of Spravato and have seen no improvement. I have an appointment tomorrow for another treatment. I really don’t like the experience. As you inhale the Spravato, you get the nasty taste. Then you’re in for a ride of feeling like you’re outside your body. Feeling like you’re completely numb. Face, feet, etc. I hate the whole experience. Everyone is different. I hope this works for others that are going to try this. Good luck!"

• JAS...
• Taken for 6 months to 1 year
• June 29, 2022

For Major Depressive Disorder "Spravato gave me a much-needed boost with the first dose. It didn’t completely alleviate my depression, but it definitely got me out of a hopeless state. I was sleeping 24 hours a day for 7-8 months, with only breaks to eat and use the bathroom. After the first dose of Spravato, I was able to play with my dog outside. This drug will give you a kickstart, but probably won’t bring you all the way out of the depression alone. I am on Wellbutrin, Pristiq, and Abilify. I see my psychiatrist once a month and a counselor weekly. The Spravato definitely gave me enough of a boost to be able to start to recover with the help of counseling and other antidepressants."

• Anonymous
• August 27, 2019

For Depression "I posted my experience earlier, and now I have done a total of 10 treatments of the nasal spray Spravato: 2 at 56 mg and the rest at 84 mg. After session 6, I started to feel a little lighter and less depressed, but this lasted very shortly. The treatments after that did nothing for me. They are very intense, and you get awful disassociation, dizziness, numbness. It's a complete out-of-body experience. For me, the feelings were very bothersome, and after I would leave, I was done for the day. I couldn’t do anything, just lay around. I guess if it worked for me, I would have sucked it up and continued even though the side effects were so bothersome. Unfortunately for me, this didn’t work, and it cost me a fortune. Personally, I wouldn’t advise others to do this until there is more research about it. It is still very new, and doctors are still learning by experimenting on us! However, the one done by IV is not as new. I will continue to fight the fight, but will never do Spravato again."

• Hop...
• Taken for less than 1 month
• July 27, 2019

For Depression "I went through a series of 6 ketamine IV infusions. It was life-changing. The drawback being that the effects and relief lasted days/weeks. But when it is working, it is miraculous. Due to a good response to the ketamine but not able to prolong the effects, Spravato was prescribed for me. I began week 1 with 2 treatments (required 2 treatments every week for the first 4 weeks). It is much milder, less intense, and effective in my view based on my response. Both dosages were at 56 mg, the required initial dose. I believe that I may have better results with the 84 mg and will be trying that dosage next week for week 2."

• DVe...
• November 4, 2021

For Depression "Have had maybe 5 Spravato treatments. Almost immediately felt better on depressive feelings associated with chronic pain. I seemed to notice the dissociative effects varied wildly from treatment to treatment and believe the stronger the effect, the more medicine gets to my brain. Today I decided not to swallow for as long as possible, theorizing swallowing what drains from the sinuses is lost to the effects of stomach acid. Well, as I swished the drainage (yeah, kind of gross, but it travels that path in any event) and avoided swallowing for as long as possible, I experienced the strongest dissociative effects to date. Makes sense as the medicine is absorbed through membranes in the mouth rather than lost to the stomach. I may be wrong, but I think the more dissociative, the more medicine gets to the brain, the more impactful the effect, the better I will feel. Will update as I continue the process, assuming I don’t drown :)"

• Cal...
• Taken for less than 1 month
• September 1, 2020

For Depression "I’ve had 5 Spravato treatments so far for depression. I felt a lightening of my mood after the first three treatments, however, the feeling didn’t last long, maybe 24 hours. I’m hopeful that with continued treatments, I will improve. I don’t have a strong reaction to the medication when it’s administered, just a slight disassociation with time and place that I can easily bring into perspective. The nasal spray dripping down your throat is horrible, and I take Zofran and omeprazole before my appointments to counter. I had 15 ketamine injections a year ago, and they helped a little. I’ve yet to have an infusion. I know that is the gold standard, but I cannot afford it financially."

• Car...
• Taken for less than 1 month
• September 5, 2022

For Depression "Spravato was recommended by my psychiatric nurse practitioner for MDD because I have struggled for more than 30 years. I was well informed of the side effects, but no one reported that anything like what I experienced. I think it’s important for anyone who is considering using Spravato to hear about as many different experiences as possible. While most experiences are positive, mine was not. After I administered the second dose, about 10 minutes or so, I began to feel like I was falling, spinning, and losing my mind, completely out of control. I sat there for almost 4 hours, absolutely terrified. Terrified that I would never feel “normal” again, that I would die, I would lose everything that I cared about. I cried in fear and begged the person who gave me the medicine to make it stop. I begged her to tell me that it would stop and that I would feel normal again. I’m still traumatized by the experience and feel like some of the effects are still happening 3 months later."

• Din...
• Taken for 1 to 6 months
• May 16, 2022

For Major Depressive Disorder "I have been using Spravato for about 4 months now, and I'm on the highest dose, and I have to say that I am actually getting worse to the point I don't think I'm going to use it anymore. Right now, at this moment, writing this, I'm in the most depressed state of mind I've ever been in. I'm so, so tired of hurting. Nothing but darkness follows and overshadows me. I just can't take feeling the way that I'm feeling. I've tried many medications, TMS, Spravato, and nothing has worked. I want to try ECT, but I can't find anyone to take my insurance. I can't eat, I can't sleep, I haven't bathed in over a year, and my hair is falling out. Plus, I have a lot of physical pain because of an autoimmune disease, I can't find anyone to prescribe me pain meds, so I'm just one big ball of pain. I was hoping Spravato would have worked, but it hasn't."

• Egg...
• Taken for 1 to 6 months
• October 15, 2019

For Depression "Starting fourth week tomorrow. Spravato has helped a little but still have anxiety, especially when waking in the morning. It may or may not work but I’m better than I was, hope it lasts. I may try Kratom if this doesn’t work, do not want to be as bad as I was. My clinician is great, and believe me, not all clinicians are that caring. I had to see someone else for one dosing, and she left me in the room for 40 minutes by myself. Not good when you're tripping out."

• H2B...
• Taken for 1 to 6 months
• September 30, 2021

For Major Depressive Disorder "It’s working for me. The first month wasn’t pleasant. I tried to go in with an open mind, but when nothing had happened during the third week, I felt desperate. Then, after the 6th session (third week), I was able to do some minor tasks that had seemed overwhelming. By the end of the 4th week, I felt significantly less depressed—no suicidal thoughts at all, less hopelessness, more willing to engage with the outside world. Feeling some pleasure. I’d estimate that I’ve achieved a 70% lift from one of the darkest and longest passages I’ve ever experienced. I’m currently stabilized at a higher level than what I’ve achieved after adjusting meds until I’m on a combo that works for a while. I ruminate less. I get off the couch occasionally. Most important, my head is clear enough that I can do some work in therapy. Unfortunately, Janssen’s long-term study was for maybe 8 months, so who knows how long it’ll work?"

• hki...
• Taken for less than 1 month
• April 11, 2023

For Major Depressive Disorder "Cannot speak to effectiveness just yet, but this is my experience. I was very nervous going into it. I do not have experience with substances other than alcohol and THC (which I respond very badly to), so I was pretty scared that Spravato would really mess me up and I'd have a bad time. I am also super prone to nausea. My first dose went just fine. Took a few minutes for me to feel the effects, but they were manageable. I was pretty lucid the entire time. My head felt a little swimmy, I sometimes couldn't feel parts of my body, and my perception of time was out of whack. But no nausea, paranoia, etc. I actually felt very pleasant the entire time. The next dose, I did have a few minor moments of panic (once because there was a loud noise, once because it was too quiet and that scared me for some reason), but they subsided quickly. I have felt pretty good in the days after my first doses, but no marked improvement yet."

• RFM...
• Taken for 1 to 6 months
• September 3, 2019

For Depression "I've been on esketamine and rapid TMS for over a month now, and I'm starting to see some small improvements. 84 mg gives me some intense reactions. I found that putting your head between your legs after you inject until it soaks in really amplifies the effects. I'd use regular ketamine, but my insurance won't cover it, and at $400 a visit, that's not going to happen. I got approved to use Spravato for a year when needed, and Janssen Pharmaceutical is picking up my copay for now. They have a plan to pay for your medication if needed, and $80,000 net a year or less qualifies. I'm planning on switching to rTMS by itself soon. It only takes 5 minutes and has no restrictions on my day."

• Ken...
• Taken for 1 to 6 months
• July 22, 2024

For Major Depressive Disorder "I have now completed 10 treatments with Spravato, and I find myself more alert, focused, less moody, and just happier overall. I was diagnosed with depression in 1992 and have taken several other medications and TMS. Everyone around me has commented on how much happier I appear. I am also doing Cognitive Behavior Therapy sessions along with the Spravato treatment. I wish I had discovered this earlier."

• Kar...
• August 8, 2019

For Depression "I have had 3 sessions of 56 mg. First time had the most dramatic side effects, very strong dizziness and dissociation. Next day I felt great. Second session had the worst reaction. Side effects last through the evening, dizziness and nausea. Next day I felt like my head was full of mud, couldn't make any decisions, had a blank look on my face all day... didn't feel like I was in this world. And the third session seemed to be somewhere in the middle. The side effects during and the evening of weren't too bad. The next day I functioned and went to work like a typical day. I can't say I have seen relief from my depression. Dr. thinks I should still give it a few more times. But I am going through a difficult time in my life, so maybe my depression would be way worse if I didn't have the Spravato treatments?"

• Anonymous
• Taken for 1 to 6 months
• May 9, 2023

For Depression "I have had MDD for years. I started to suffer from depression as an adolescent, probably due to my environment and situations I had been exposed to. Anyway, I have been on just about every SSRI, SNRI, and also antipsychotics and benzos for most of my life. Currently on Trintellix. I have had four Spravato treatments so far. The first treatment was horrible. I relived traumatic experiences in my mind, and the physical effects were almost unbearable. I had such a frightening experience that the doctor was hesitant to have me come back. I am desperate, so we decided to have my spouse sit with me to help keep me in a positive state. This helped. However, I felt hungover the next day and couldn't think clearly. Next treatments only improved slightly, still very uncomfortable, I couldn't wait for the treatments to be done. On the eves of treatments, I had very restless legs and had a panicky feeling. It's been two weeks, and I don't feel any better. In fact, I feel a little worse."

• ken...
• Taken for 6 months to 1 year
• September 20, 2022

For Major Depressive Disorder "Who needs therapy when there’s Spravato? Paradoxically, my own reservations almost kept me from trying this drug that turned my entire life around. I went from sleeping on the floor at my mom's and in an abusive long-distance relationship to getting my own place and finally having the courage to leave the relationship. At the twice-a-week regimen, I was even going to the gym after work - pretty much unheard of for me in the last decade. I was discouraged to find that when I tapered to once every other week, my depression seemed to be making its way back, however, I am very lucky to be treated at a place that allows me to go back to more frequent visits. I cannot say enough good things about Spravato, and I’m not sure what my life would be without it. Lexapro took me out of a completely mental state, and Spravato ensured I stay there."

• Kay...
• Taken for 1 to 6 months
• November 6, 2022

For Major Depressive Disorder "My major depressive disorder is drug resistant. I used Spravato at a doctor's office 3 times weekly for about 6 weeks. My first 2 weeks were filled with sadness, followed by mad anger (PTSD symptoms) for the following 2 and experienced deeper sadness and suicidal ideation for the last two. We then stopped treatment about a month ago, and I am still struggling with deep sadness. I feel disappointed. I had been so hoping for lasting help. I've begun to lose hope that I'll never again experience life with more delight."

• Des...
• Taken for less than 1 month
• July 4, 2022

For Major Depressive Disorder "Spravato ended up making me have suicidal thoughts, and I think maybe go into a psychosis or something... I took it for a month. Twice in one week, 34 mg, and then the rest ones were 84 mg once a week. You take it like a nasal spray, and it burns a lot. I just couldn’t move and felt drunk, like mucked up, seeing tracers for about 45 minutes maybe. I didn’t like how I couldn’t move. I was completely numb, it helps pain for that time. But when it wore off, I was still numb mentally. I would get angry when it wore off. It just has to be known, it made me worse. They told me it was impossible to feel worse, which is so stupid. I also have PTSD, social anxiety, and generalized. Spravato made me take a lot of steps back. I had worked so hard to the point to where I was, and it tore it all down. Now I am a lot better and building it back up. But I just still don’t feel 100%. I hope I do. It made me aggressive, I wanted to fight people and harm myself. I used to be addicted to self-harming."

• Goo...
• Taken for less than 1 month
• November 5, 2021

For Major Depressive Disorder "I complete week 4 Monday. 84 mg is super strong - can be trippy. Start with 56 mg. Do NOT drive for several hours. Do NOT move around much during the session as you could get nauseous. My depression is much improved so far. Improved, but this is not a magic bullet."

• Kjo...
• Taken for less than 1 month
• January 2, 2020

For Depression "An exciting experience that lifts you into a different way of looking at many things. Colors and objects appear more enhanced and even strikingly different than usually experienced, but quite interesting and most surprisingly more in depth."

• Ana...
• Taken for less than 1 month
• April 10, 2020

For Depression "I would like to know if anyone else currently being treated with Spravato has had insomnia, flashbacks, extremely weird, and vivid dreams? I have only completed 2 treatments so far and am curious as to how it is affecting others."

• Ric...
• Taken for less than 1 month
• February 22, 2022

For Major Depressive Disorder "I am using this for PTSD. The drug experience is horrible. After I spray it in my nose and it begins to take effect, I pray it will end. The feeling is so horrible. I want to throw up, I can't physically move, I can't assess where I am, I can't 'sense' anything, but I am aware of how bad I feel and pray it ends. For 24 hours after each treatment, I am a worthless dish rag. I feel my brain will never come back. No ability to think and want to vomit. I can't take many drugs. I have severe reactions. I opted to try Spravato because it is not every day. You won't want a soul near you when under the effects in the office. I feel I am in prison. Trapped. Can't scream. Buried alive with no help. It is a bad trip. If it treats PTSD, it is worth more than the nightmare side effects, that is the only reason I tried it. I have had allergic reactions to everything ever given to me. I am not allergic to Spravato. I just am terrified of how it makes me feel. I dread treatment."

• And...
• Taken for less than 1 month
• April 29, 2023

For Depression "My first treatment was actually exceptionally frightening. When it appeared to peak, I could not move and felt frozen. A very low, soft, short mumble of a couple of words when asked a question. Lips barely moved. Very, very dark and distorted visual when eyes are closed. Open eyes, very difficult to see, and also quite dark. Felt very, very trapped. Wasn't sure if I was dying. Remained highish for several hours after. Also, the next 2 days had negative side effects, which a friend also observed. Never again!"