Spravato and Depersonalization: What Users Say

• Anonymous
• August 27, 2019

For Depression "I posted my experience earlier, and now I have done a total of 10 treatments of the nasal spray Spravato: 2 at 56 mg and the rest at 84 mg. After session 6, I started to feel a little lighter and less depressed, but this lasted very shortly. The treatments after that did nothing for me. They are very intense, and you get awful disassociation, dizziness, numbness. It's a complete out-of-body experience. For me, the feelings were very bothersome, and after I would leave, I was done for the day. I couldn’t do anything, just lay around. I guess if it worked for me, I would have sucked it up and continued even though the side effects were so bothersome. Unfortunately for me, this didn’t work, and it cost me a fortune. Personally, I wouldn’t advise others to do this until there is more research about it. It is still very new, and doctors are still learning by experimenting on us! However, the one done by IV is not as new. I will continue to fight the fight, but will never do Spravato again."

• Cal...
• Taken for less than 1 month
• September 1, 2020

For Depression "I’ve had 5 Spravato treatments so far for depression. I felt a lightening of my mood after the first three treatments, however, the feeling didn’t last long, maybe 24 hours. I’m hopeful that with continued treatments, I will improve. I don’t have a strong reaction to the medication when it’s administered, just a slight disassociation with time and place that I can easily bring into perspective. The nasal spray dripping down your throat is horrible, and I take Zofran and omeprazole before my appointments to counter. I had 15 ketamine injections a year ago, and they helped a little. I’ve yet to have an infusion. I know that is the gold standard, but I cannot afford it financially."

• Kar...
• August 8, 2019

For Depression "I have had 3 sessions of 56 mg. First time had the most dramatic side effects, very strong dizziness and dissociation. Next day I felt great. Second session had the worst reaction. Side effects last through the evening, dizziness and nausea. Next day I felt like my head was full of mud, couldn't make any decisions, had a blank look on my face all day... didn't feel like I was in this world. And the third session seemed to be somewhere in the middle. The side effects during and the evening of weren't too bad. The next day I functioned and went to work like a typical day. I can't say I have seen relief from my depression. Dr. thinks I should still give it a few more times. But I am going through a difficult time in my life, so maybe my depression would be way worse if I didn't have the Spravato treatments?"

• Anonymous
• Taken for less than 1 month
• July 22, 2019

For Depression "So far, I am on my 3rd time doing the Spravato nasal spray. 2x I did 56 mg and one time the 82 mg, I believe. I feel exactly the same. No change at all!! My Dr told me to at least give it to the one month mark. It makes me feel awful during it, I get the disassociation and dizziness along with every other side effect, and I will say it takes me more than 2 hours to wear off. Pretty much the whole day. I am hoping the next few treatments work, otherwise, I have wasted a lot of time and money :-("