Spravato Interactions
There are 297 drugs known to interact with Spravato (esketamine), along with 4 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 267 are major, and 30 are moderate.
- View all 297 medications that may interact with Spravato
- View Spravato alcohol/food interactions (2)
- View Spravato disease interactions (4)
Most frequently checked interactions
View interaction reports for Spravato (esketamine) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- albuterol
- Auvelity (bupropion / dextromethorphan)
- baclofen
- bupropion
- buspirone
- clonazepam
- clonidine
- Cymbalta (duloxetine)
- famotidine
- gabapentin
- hydroxyzine
- ibuprofen
- lamotrigine
- levothyroxine
- melatonin
- metformin
- omeprazole
- ondansetron
- pantoprazole
- prazosin
- propranolol
- Rexulti (brexpiprazole)
- tizanidine
- trazodone
- Trintellix (vortioxetine)
- Vitamin D3 (cholecalciferol)
- Vraylar (cariprazine)
- Vyvanse (lisdexamfetamine)
Spravato alcohol/food interactions
There are 2 alcohol/food interactions with Spravato (esketamine).
Spravato disease interactions
There are 4 disease interactions with Spravato (esketamine) which include:
Report options
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More about Spravato (esketamine)
- Spravato consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (125)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: miscellaneous antidepressants
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
