Dulaglutide and Nausea: What Users Say

• mam...
• Taken for 6 months to 1 year
• January 4, 2021

Trulicity (dulaglutide) for Type 2 Diabetes "My husband of over fifty years was put on this drug at the beginning of 2020. He was over 270 pounds, and his A1C was over 11. The doctor was desperate. My husband experienced horrible nausea and abdominal pain. He began to lose weight but not as fast as the doctor wanted. He was put on concentrated insulin twice a day. He started becoming sicker. He was taken to the ER in August of 2020. He was placed on a ventilator for respiratory distress. He suffered three strokes while in a medically induced coma. He never recovered. I don't know what the answer is to this drug and who should or should not take it. I'm just saying that anyone who starts experiencing bad symptoms should not wait until the doctor takes them off of the drug. Be your own advocate!"

• Mic...
• Taken for less than 1 month
• August 2, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "Well, this is my second review on this drug. I am now on my 3rd week of taking Trulicity and can happily report I’m getting on brilliantly, no more side effects, not that there were many anyway, just slight wind and nausea. Very, very easy and painless to inject. Sugar levels gone from 18 to 5.5-6, therefore being able to reduce my daily insulin dose significantly. Appetite cut in half, not really losing weight yet, but I have every faith that I will eventually. There are so many bad reviews on here that I read and was therefore worried sick about starting this drug, but in my experience, it’s a miracle and this has to be shared as well. I really hope first-time users give it a go and have success as I have."

• Gin...
• October 22, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "I took the Trulicity shot on Friday, today is Tuesday. Until today, no side effects until I decided to eat a donut today, which I know is not diabetic-friendly... I got so sick, nauseated, dizzy, fatigued, I thought I would have to go to the ER. I eventually had several normal bowel movements and a long nap. The first day or two, I felt really weird. Not myself. Appetite is definitely almost nonexistent. And for me, that is a huge plus. I have been overeating like a mad person for years. I am not sure how this stuff works, but it does! Instantly, my blood sugars are in record lows for me. I've been a type 2 diabetic for nearly 15 years. I've never had sugars like a 'normal' person since my diagnosis, until this week! I cried when I saw how good they are! Together with my insulin regimen, I am on my way to a lot better health. I am so grateful for the change! Will update again after a few weeks"

• Pum...
• Taken for 6 months to 1 year
• April 7, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "Oh gosh, I truly feel like I’m dying. This is the 3rd week of 1.5, and I’m so sick. I can’t hold food down, I’m jittery, with increased heartbeat, and all I can do is wait for it to leave my system. I’m so weak and frankly scared. This is it, I’ve really had it. I’m done with this medicine."

• Ric...
• Taken for less than 1 month
• February 13, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "Dr. prescribed in the fall. Reading these reviews I was TERRIFIED. Dr. insisted that he had never had a patient with such experiences. Spoke with a friend who was on it. He reported a little nausea the first couple of weeks but it subsided. So far, I have experienced NO side effects other than a little gas. Very tolerable. Looking forward to seeing my labs next month."

• Pin...
• Taken for 1 to 6 months
• July 22, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "Wanted to share my review of Trulicity because my experience has been a positive one. I was so afraid to take this after all the bad reviews. I know that everyone's experience on a med is different, but I'm glad that I gave this a try. It's been 4 weeks now, and I have experienced little to no side effects. A bit of dizziness the first week was about all. After 1 month on Trulicity, my A1C has gone from 8.3 to 6.6. I had previously tried both Metformin and Metformin XR and could not tolerate the constant nausea and diarrhea. So far this med has worked well for me, I'm down 8 lbs after one month, and have more focus and energy. I'll continue on with the med, and will update if anything changes."

• Jak...
• June 10, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "I was diagnosed with type 1.5 LADA (Latent Autoimmune Diabetes Adult Onset) in November 2019. By December, my endocrinologist prescribed Trulicity along with a Metformin ER pill. This injection was always painful, and the first day or two after the injection, I always felt very nauseous. I've experienced upset stomach and abdominal pain off and on throughout my whole time on these meds. My A1C and other blood work numbers were good, so the doctor decided, with my complaints and good numbers, I went off the Trulicity but continued the Metformin. A week later, I'm in my gastro's office with LLQ pain and am told I have a partial intestinal blockage. It is now June 2020, and I just got out of the hospital with Acute Colitis (forgot to mention that I'm only 20). The biopsy came back showing the cause of my problems as medication. I can't help but blame this on Trulicity and Metformin since I'm not on other medications. I've seen comments about gastro upset but nothing as serious as colitis."

• eva...
• Taken for 1 to 6 months
• August 29, 2018

Trulicity (dulaglutide) for Type 2 Diabetes "I was waiting a long time (a year) until I started using Trulicity pen. Why? I was scared after reading many reviews about side effects. But when metformin was not effective and I had constant UTIs which meant antibiotics, I didn't have a choice. I wish I had started it earlier. I have no side effects! The shot is not painful and easy to do, no diarrhea, no mood changes, no vomiting, no stomach pain, no gases. Yes, I have a little less appetite, especially in the morning, a little fewer visits to the bathroom for number twos (but I have at least one movement), a little nausea sometimes but nothing bothersome, not even noticeable. Each person reacts differently, usually bad reviews are from people with a strong negative reaction to the medication. That's why I am writing this review. Maybe somebody who really needs this medication will not be scared to try it as I was. I gave fewer stars because the lowest dose didn't lower my morning sugar level. Maybe more side effects will come with a higher dose, which I need to try."

• Kat...
• Taken for less than 1 month
• February 17, 2021

Trulicity (dulaglutide) for Type 2 Diabetes "Started on this medication only two weeks ago due to having an adverse side effect with another medication. According to my doctor, 'it's a great drug that will actually help you lose weight.' Sure, I have already lost weight, all due to having not been able to keep down a single bite of food. For the first day after my first dose, I noticed my body feeling sluggish and short-winded, then the nausea and vomiting kicked in. Hoping the horrific toilet bowl hugging would improve, I tried a second dose in week 2, but the result was only more praying to the porcelain gods. Now, I need to get off this ghastly med too."

• Pet...
• August 16, 2017

Trulicity (dulaglutide) for Type 2 Diabetes "Finally I have found a drug that works for me! In 2 months I have lost 25 lbs. My sugar levels are at an all-time low. Yes, I get some nausea and a little upset stomach but nothing different than before being on other shots/meds. What I have found that works for me is eating a heck of a lot less. If you're not feeling hungry, don't eat unless your sugar is low, of course. Eat very small portions. If you start to feel full, STOP eating! Very small portions and relax. That's my $0.02. This is the best drug I have found since being diabetic but being a realist, drugs react differently to the individual. You won't know till you try."

• Mis...
• Taken for 1 to 6 months
• December 24, 2018

Trulicity (dulaglutide) for Type 2 Diabetes "Started taking Trulicity 11/2018. Began with 0.75 ml for two weeks. Slight side effects of a little gas and nausea. Nothing else. Bumped up to 1.5 ml and the gas and nausea got a bit worse but went away quickly. Anything greasy results in mild diarrhea so I’ve eliminated all greasy foods from my diet. If you pay attention to what you eat, you can eliminate the side effects. Please be aware you definitely can’t eat the same amount of food as you did prior to taking this medication. I have lost 17 lbs in 6 weeks. It’s a great drug. You just have to pay close attention to what and how much you eat."

• Emi...
• February 12, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "I was on Trulicity for 6 months. The first 5 months, my symptoms were mild enough that I could manage them. Around 5 months in, I started getting extremely bloated, gassy, sulfur burps, extreme fatigue, diarrhea, nausea, vomiting, and headaches. I would get sick 2-3 days after my injection. Since stopping Trulicity, I've still periodically gotten sick (extreme bloating, gas, sulfur burps, diarrhea, vomiting, extreme fatigue). I've had my low-functioning gallbladder removed, and I've had an EGD done... and I'm still sick. Nobody can seem to diagnose or fix the digestive issues Trulicity has caused me. I've been off of Trulicity for 10 months. I'm at my wits' end. I wish these awful effects would go away for good."

• FLB...
• May 4, 2017

Trulicity (dulaglutide) for Type 2 Diabetes "This medicine is the best! I'm type 2 diabetic. Side effects: some light nausea for a couple of days only. My sugar levels were out of control, ranged from 250 to 450 before Trulicity 1.5. I found this forum looking into the feedback of Trulicity users and I was terrified of the side effects users had and posted in here. Regardless of my concerns, I decided to go for it. This is my 3rd week and my sugar levels are like never before, ranging from 110 to 140 (after meal). No side effects, the hunger is gone as well as less of an appetite. I lost 12 pounds in almost 3 weeks. I have not had any hypoglycemic events. I'm very happy to finally get my levels in control."

• Kar...
• April 30, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "I have been on this medication for about six weeks. I just took my seventh-week shot two days ago, and I feel like I am dying. I am nauseated, dizzy, weak, extreme diarrhea, and I have burning and numbness in my legs and feet. I was initially taking Victoza, which I did very well on, but I lost my insurance and could not afford the hopper tags. So my doctor tried me on Trulicity and I honestly feel so bad. I have a month's worth of shots left, but I am trying my best to get this medication out of my system. Talking to my doctor about something new. Praying for us all."

• Jus...
• Taken for less than 1 month
• May 21, 2023

Trulicity (dulaglutide) for Type 2 Diabetes "I started taking this medication last week, exactly a week ago today. It has been a horrible experience. The very next morning, I felt extremely nauseous and couldn't eat or drink anything throughout the day. I became so nauseous that I ended up getting dehydrated and started vomiting. I was sick all week long and almost went to the hospital every day. To be honest, I have had my fair share of long hospital visits and was hesitant to go to the emergency room. However, looking back, I should have been there multiple times this week. I'm not exaggerating. The fact that I am starting to recover from this sickness feels like a miracle. I became malnourished because I couldn't keep anything down, and now my body is struggling to absorb nutrients properly. As a result, I am experiencing shakiness, nausea, tiredness, irritability, and an overall horrible feeling that I can't seem to shake off. If you can, please pray for me. Thank you, and may God bless you. I urge you to exercise caution if you decide to use this medication and don't wait for the symptoms to accumulate. If something doesn't feel right, trust your instincts."

• Hap...
• Taken for 2 to 5 years
• July 24, 2023

Trulicity (dulaglutide) for Type 2 Diabetes "I have been using this medication for over two years and I must say I’m very happy with it. The only side effect I get every now and then is a little nausea, if I eat something with too much grease, it doesn’t have to be fried. Even if it’s baked with lots of cheese, and cheese makes the food greasy, I will get nauseated. The injection site still hurts, other than that, I am happy with it. Because I have some serious issues in my discs that cause me severe pain, I can’t do intense exercises except walking a little at a slow pace. Over the past two years, with the help of this medication and the little walks I take on a daily basis, I have lost well over 150 pounds, and my A1C is down to 5.6. This was a lifesaver for me. I am sad to see so many bad reviews on here regarding this medication. No medication is a miracle ready to happen overnight, and nothing is without side effects, even Tylenol may give side effects to some people. Give it time to work and add other activities into your daily routine."

• kcc...
• January 14, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "I was put on Trulicity to go with my Metformin (1000 mg 2x a day) in late July of 2018. My doctor warned me that I might get nauseous the first few weeks after the shot when I eat too much, something that was high fat or something greasy, and that I was to just try to go with it and not eat additional carbs like saltines or bread to calm my stomach. She was right. I got nauseous. After 2 months, I had lost 20 lbs., but my sugars were the same. I changed my diet, eating no gluten, no sugar, and low carb, lots of veggies, and higher non-animal protein. I went back to my endocrinologist, and my A1C was down to 5.7, my fasting blood sugar 91, and my after-meal blood sugar down to 118-130. I had lost an additional 20 lbs.! So in 6 months, 40 lbs. total."

• daw...
• Taken for 1 to 6 months
• June 18, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "I tried Trulicity for 4 months, the stomach upset and sulfur burps were the worst, not to mention the stomach pain, nausea, and increased my acid reflux. Had to take two Protonix and Prilosec a day and still had heartburn from this injection. It's been 3 weeks since I stopped Trulicity. I am doing much better but still have the burps that I never had before this injection. Depending on what I eat, they turn into sulfur burps. Dropped my A1C from 8.8 to 8.4, lost 8 lbs. But not worth the stomach issues."

• Ste...
• Taken for 1 to 6 months
• May 17, 2021

Trulicity (dulaglutide) for Type 2 Diabetes "I've been on Trulicity since January of this year, having one dose once a week. It still makes me feel nauseous. My side effects are I can't eat, bloating, diarrhea, painful pain in the lower abdomen. I've mentioned all this to my doctor, and she keeps saying my body just needs to get used to it. Don't think it will ever get used to this."

• Anonymous
• Taken for less than 1 month
• January 28, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "I took one shot of Trulicity 2 weeks ago. I missed a whole week of work because of nausea, dizziness, fatigue, and vision problems. I can’t think straight. I called my doctor and told her I was not taking this again. It’s been 2 weeks and I still feel horrible! Dizziness and nausea are terrible. Achy all over. How long does this stay in our bodies?"

• bes...
• November 3, 2015

Trulicity (dulaglutide) for Type 2 Diabetes "I started Trulicity about a year ago because the medication I was on kept crystallizing and was hard to inject. I have lost weight, about 22 pounds, over the course of a year. The biggest things to get used to were the nausea and the diarrhea, but after giving 4 weeks to adjust to the medication, my blood sugar does not spike like it used to, and I felt better. I don't have my usual cravings for anything bad for me, but I do have an appetite. I tell anyone who needs to lose a few pounds and lower blood sugar to stick with it. It will get better. I can't complain about the medication. All anti-diabetic agents cause stomach issues. Hang in there."

• kat...
• Taken for less than 1 month
• May 9, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "Nope! Trulicity is not for me! Vomiting every day multiple times, nausea, fatigue. I can't even lift my arm to brush my teeth or walk 10 feet without feeling like I'm going to pass out. Heart beating out of my chest. Only had one dose, never again. Poison!!!"

• Zoe...
• Taken for less than 1 month
• November 2, 2020

Trulicity (dulaglutide) for Cardiovascular Risk Reduction "I was prescribed this for weight loss, and it has been the worst thing ever. Bedridden and unable to work for 6 days now. Vomiting and diarrhea the whole day. Complete loss of control of my bowels. Unable to care for my kids. BP dropped to 74/48 at one stage, been to ED yesterday for IV fluids, but today it's worse than ever! Severe gastric upset, gas, pain, weakness, fatigue. Constant nausea that Maxolon and Ondansetron doesn't touch! I feel so awful! Don't risk this! I have heard of many now who have had these severe symptoms. I have not been this sick in 15 years! Diarrhea every 15-30 mins, using nappy rash cream on my bum now. Nightmare!"

• Dap...
• Taken for 1 to 6 months
• September 12, 2019

Trulicity (dulaglutide) for Type 2 Diabetes "It's been almost 4 weeks now since I've been on the Trulicity 0.75 mg weekly. I did experience some mild nausea and a few headaches, but overall, my experience has been great. My appetite has decreased a lot. I was advised to stay on the 1000 mg of metformin at bedtime by my endocrinologist, which balanced out the constipation and diarrhea. I am, however, gassy... lol... but I can deal with that. I have experienced some weight loss, but I don't know how much. I see it in my clothing, and I feel much lighter. I also have increased energy."

• Ell...
• Taken for less than 1 month
• April 3, 2020

Trulicity (dulaglutide) for Type 2 Diabetes "This is the worst medicine ever, and I’ve taken quite a few. I had to take Trulicity because my insurance won’t cover Victoza without a fight, and this is the second time I’m given low-rated/poorly tolerated medication for this reason. Thanks, Tricare. That same night, I had awful stomach cramping and diarrhea. Then the stomach pain was a little less severe but more persistent. I also suffered fatigue, constipation, bloating, sulfur burps, heartburn, nausea, dizziness, poor sleep, nightmares in addition to the stomach pain. Once it was so bad, it woke me up! I had constipation switched with diarrhea and heartburn for almost 2 weeks, and I stopped the medicine already. It stays in your system for DAYS and still messes with you. It’s awful."