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Unisom SleepTabs and Headaches: What Users Say

Headaches: mentioned by 7 users (8.6%)

Based on user experiences from 81 Unisom SleepTabs reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

drowsiness 22.2%
dizziness 11.1%
headaches 8.6%
anxiety 4.9%
dry mouth 4.9%
depression 3.7%
irritability 3.7%
nausea 3.7%
sleepy 3.7%

Reviews for Unisom SleepTabs

Commonly mentioned side effects
  • 3rd...
  • January 15, 2020

For Insomnia "I have tried melatonin (3 mg) to help sleep during the day, as I work 3rd shift, but it doesn't work as well as I'd like. So, I figured I would give Unisom a try. My head feels like a pressurized can ready to explode, headache, diarrhea, a slight labored breathing/weight on chest feeling, and completely lethargic. Missed work as a result. Won't be taking this again."

2 / 10
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48 Report
  • Deb...
  • Taken for 1 to 6 months
  • February 12, 2019

For Insomnia "Started taking doxylamine succinate (aka Unisom) for occasional sleeplessness about 6 weeks ago. I'm a 59-year-old woman, healthy, menopausal. Box says the dose is 25 mg. I started with 12.5 mg because I'm sensitive to most meds. It worked VERY well. I fell asleep fast and stayed asleep, no issues except maybe a mild drowsiness feeling during the day here or there. Fast forward to last week, I'm experiencing dizziness, mild balance issues, headache. Don't know if it's because I took it 3-4 days in a row sometimes and stopped for a day or two? I just know it's a bummer because it works, but this stupid dizziness and balance thing is hanging on into day 2, and I don't want to take it anymore because of that. They say it's 'not habit-forming.' I think my body got used to it and I'm 'withdrawing.'"

10 / 10
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39 Report
  • MRC...
  • Taken for 1 to 6 months
  • April 26, 2018

For Insomnia "Heard about this from a friend. It works well. I usually wake up a few times during the night but slept like a baby when I took one gel tablet. The only thing is that the following day I would be very cranky and had a massive headache. Will not be taking this anymore!"

4 / 10
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17 Report

Frequently asked questions

  • Pre...
  • August 11, 2015

For Insomnia "I'm pregnant and my doctor recommended I take Unisom and B6 at night for my morning sickness and nausea. When I took it, I easily fell asleep, but I could not sleep through the night, I would wake up at least 3-4 times. I woke up irritable (more than normal for being pregnant), and it also triggered my migraines. Almost every time I took this, I would get really bad headaches."

2 / 10
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28 Report
  • Hbl...
  • Taken for 1 to 6 months
  • November 24, 2021

For Insomnia "So I am 24 weeks with my 2nd baby, and my bed has become very uncomfortable. I wake up multiple times, tossing and turning. My doctor told me I can take these tablets. The only thing I would say is, if you haven't taken them before, take half a dose. I took the whole dose and went to sleep, woke up late, and ended up taking a 5-hour nap and am still tired, with a minor headache as well."

9 / 10
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5 Report

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  • Amp...
  • Taken for 2 to 5 years
  • February 17, 2022

For Insomnia "I’ve been taking Unisom Sleep Gels for 3 to 4 years every night. I was first suggested them by my OB/GYN while I was pregnant for nausea and for insomnia. I have no side effects while taking it. When I try to stop, I get serious nausea, cold sweats, and headaches, it’s like really bad."

7 / 10
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3 Report
  • Kal...
  • March 15, 2015

For Insomnia "I took 1 50 mg tablet of Unisom; it didn't work, so I took another one. I fell asleep 4 hours later, and when I woke up, I had the worst headache of my life and a bad taste in my mouth for a whole week straight."

1 / 10
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27 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.