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Doxylamine / pyridoxine User Reviews & Ratings (Page 3)

Brand names: Diclegis, Bonjesta

Doxylamine / pyridoxine has an average rating of 7.3 out of 10 from a total of 165 reviews on Drugs.com. 63% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Doxylamine / pyridoxine

  • Kat...
  • June 9, 2018

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I know this doesn’t work for everyone, but before I started it, I was praying for twins because I didn’t think I could take another pregnancy. Since I started it, my whole experience has been completely different, and I feel amazing! Worth every penny!!"

10 / 10
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  • Lif...
  • August 30, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I have been taking Diclegis since I was 11 weeks pregnant. Prior to that, I was vomiting maybe twice a day and felt nauseous all day long (except at night). The first time I took Diclegis, I was in HEAVEN!! I felt so good. I was able to go a full day not even thinking about feeling sick. I thought that would be the effect the whole time. Not! I am 3 weeks in with taking Diclegis, and it seems like the effect of it has worn off to a certain extent. I am back to feeling nauseous most of the day. I will say that the vomiting is still under control, but I vomit maybe once every 4-5 days (which is still progress). I am in my 14th week now, and I want to see how I will feel if I don't take the meds, but I'm scared, lol!"

7 / 10
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  • KT1...
  • Taken for less than 1 month
  • February 1, 2020

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I was experiencing pregnancy nausea without vomiting from week 6 to current (week 8). I wasn’t able to eat, really only able to rest in bed for the most part. I tried Bonjesta, and it’s helped a great deal. I still experience slight nausea, but it’s bearable, and every so often I will actually feel hungry and am able to eat like normal. I have tried Zofran as well, which does help with nausea but backs you up badly, so be careful."

10 / 10
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  • Lor...
  • Taken for less than 1 month
  • March 30, 2020

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I guess some of us are lucky to have this pill work for morning sickness, I am not one of them. Started at my 4th week, I am now 11 weeks. The pill made me worse!!! Felt like a tranquilizer and knocked me out!!! Not good when you have a 6-year-old. By my 4th day, I was still nauseated and throwing up. Yes, I would see the somewhat dissolved pill in my throw up. Gross, I know. My doctor is not going to put me on an IV pump because I am not losing too much weight, not good!!! Wish you ladies the best and hope this helps."

1 / 10
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  • Ram...
  • November 17, 2015

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "So I took Diclegis for the first time last night after my doctor prescribed it. My first pregnancy, I was sick for all nine months, multiple times a day. I am now almost seven weeks with my second, and the nausea and vomiting are starting again. I took the pill around 7 PM, which may have been a little too early. I did notice about an hour after taking the pill I got some slight chest pains, but nothing too serious. I slept like a baby all night, only getting up once to use the bathroom around 5 AM. The reason I gave the drug a rating of 7/10 is because of how I am feeling this morning. I have not had any nausea or vomiting, and have actually been able to eat a decent breakfast this morning. I am, however, stuck in this constant fog."

7 / 10
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  • Mom...
  • Taken for less than 1 month
  • July 14, 2019

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "With my first daughter 5 years ago, I had pretty bad nausea but managed to get through it without needing any medication. This time around was a completely different story. I really tried to not take any medicine, but after two days of being unable to consume any food, it was time (I was 6 weeks). My doctor prescribed me Bonjesta and warned me it would make me tired. Boy, was she right! I took this the first night around 9 PM, woke up the next day, and within 2 hours, I had to lay back down for a 3-hour nap. The nausea has mostly gone away, but tonight it came back. I haven’t been taking it twice a day yet as I’m afraid I’ll be a zombie, but I think I might need to. Works great for the morning sickness, but I just wish it didn’t make me so tired! Also, this is expensive. My insurance covered $600+, but I still had to pay about $135 out of pocket."

8 / 10
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  • Pin...
  • Taken for less than 1 month
  • December 16, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "It actually makes me vomit violently. It feels like it's burning a hole in my stomach. I've tried 3 different times. I have hyperemesis and I take Zofran and Phenergan, and when I try to add Diclegis, I vomit 10x back to back until it's out. Awful, awful stuff."

1 / 10
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  • JG7...
  • Taken for less than 1 month
  • November 18, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I am currently 7.5 weeks pregnant, and I started experiencing debilitating nausea at about six weeks. I've been taking Diclegis for a few days now (2 before bed and 1 more during the day if necessary), and it's helped quite a bit. My nausea has decreased between 60 and 80%, and my appetite is returning. I actually went out to dinner with friends last night and enjoyed myself! I have had some drowsiness, but I can still get through my work day OK. And thank goodness for my great prescription coverage - $40/100 tablets! I hope it continues to control my symptoms this well."

9 / 10
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  • SBi...
  • Taken for less than 1 month
  • June 22, 2019

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I’m 10 weeks pregnant and started getting nausea at 6 weeks. I was prescribed Zofran initially, and that didn’t really help. Now on Bonjesta, and it’s an improvement. I do have to take it morning and evening, but it helps keep the nausea under control and sometimes takes it away completely. It’s still a bit of a struggle because it does make you more tired, but I’ll take it. Anything but this nausea, please."

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  • kim...
  • August 23, 2015

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "This medication works wonders! I can take it without having to eat something before, which was so helpful, considering I couldn't hold any food down! I lost more than 20 lbs due to vomiting and nausea. And getting into a moving vehicle was the worst! I take one in the morning and I feel good all day! I love it so much, lifesaver."

10 / 10
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  • Not...
  • August 24, 2017

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I took three. 1 in the morning, 1 around 1 p.m., and the nausea didn't stop, so I took another one. My doctor said I should take 1 before every meal and 2 before bed or as needed. The label says take 2 pills before meals. My point being, it made me feel horrible. It made me feel drugged up. I didn't want to move, I felt like I want to throw up and go #2 and just get out of my body. I'm never taking that again. It's 9:30 p.m., and I still feel drugged up. This drug is an antihistamine and messes with your brain. I should've read about it before taking it. Although I'm 8 weeks pregnant and nauseous all day, and my doctor said it is given to all OB patients, so I trusted him."

1 / 10
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  • Fre...
  • August 24, 2017

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting "This medication gave me my life back. I started it yesterday, and I do not need any more time to try it out to review it. I was throwing up so much that I had thoughts of suicide and/or termination of pregnancy... and we planned for this baby. Anyone who knows me knows those thoughts are insane for me, but I couldn't take another day of laying in bed throwing up. I was expecting to fall asleep and not wake up based on the comments, but I woke up completely fine at 6 a.m., and I took 2 pills before bed at 10 p.m. I was pretty tired until 11 a.m., but I will take tired ANY DAY over being sick and nauseous. I could sleep like crazy right now, but I will not stop taking these meds. It was $894 before insurance for 120 pills, and my copay was only $40!!!!"

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  • Jsi...
  • April 23, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I have been feeling pretty nauseous all day (first trimester of pregnancy), and my healthcare provider gave me a sample of this drug to try. I wanted to share my experience, as all I've read are glowing reviews. Glad it's working for some people, but I have to imagine there are others who experienced something similar to me. I have taken it now for 3-4 days, which should have been enough time to get a feel for whether or not it works. It did absolutely nothing for my nausea. If anything, it made me feel worse. I was so tired I couldn't function. Had to lay down in the middle of the day for a few hours, feeling so tired and sick. I didn't take any last night, and today I feel better than I have since I started taking it!"

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 23, 2023

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I had severe nausea that lasted 24/7 starting at week 6 of my pregnancy. I talked to my doctor at my 8-week appointment and was prescribed Bonjesta. When I first started taking it, it felt like it was only working for a couple of hours, but by dinner time, I was super sick again. After a week of being on it, my nausea is pretty much completely gone!!!! I can actually cook dinner for my family again and eat normal foods that aren't crackers or Honey Nut Cheerios. Give it a week to work, I promise it works!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 6, 2017

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "This medicine works wonders! I was having severe nausea and vomiting every morning to the point I was losing so much weight. My doctor prescribed me Diclegis. I take 2 at night and one during the day because of how tired it makes me. Ever since I've been taking it, I've been able to hold down food and water, and I've also gained an appetite. Without these, I wouldn't be able to go to work. I love them!"

8 / 10
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  • Rag...
  • Taken for less than 1 month
  • September 23, 2015

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I took two of these pills and went into a full on RAGE for 6 straight hours. I couldn't control my emotions, my eyelids kept twitching, I felt like I was pumped full of anti-depressants and was in a cross-eyed fog. My nausea was definitely gone considering all the new horrible feelings I was enduring. The nurse said to "give it time". I have a two year old - I don't have a week or even a few days to be fueled by hatred and impatience. This medicine is horrible. Don't take it unless you want to experience extreme mood swings and irritability."

2 / 10
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  • Ebr...
  • August 24, 2015

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "This medication is the only medication on the market that has allowed me to live my normal life. I started taking it around twelve weeks pregnant because I was losing weight rapidly and couldn't even keep sips of water down. At first, I had to take two at night and one in the morning to function. I am now fourteen weeks and have been getting by on only two a day. I tried not taking any at all today, and I was great up until 9 PM, then I got so sick I threw my whole dinner up... unexpectedly. Immediately took two pills and now I feel much better. The only downside is how expensive this medication is. It cost me $186 per bottle of 100."

10 / 10
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  • Dom...
  • Taken for less than 1 month
  • September 25, 2019

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "Saved my life is an understatement. I suffered so badly with morning sickness with my first daughter, and Zofran didn’t work at all. I was sick the whole 8 months. With this pregnancy, I experienced HG again, but this medicine literally gives me my life back. It does make me a little sleepy, but I’ll take sleepy over nonstop heartburn and vomiting any day."

10 / 10
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  • JST...
  • June 11, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I started taking this during the first trimester. I'm usually against taking medicine, but I was so sick. So, I figured it was worth a try. At first, I didn't notice any change. I mean, I was still slightly sick. I was expecting the nausea to disappear completely like Zofran would have done. I kind of thought it wasn't working, so I decided to stop taking it... big mistake... my nausea was severe once I stopped taking it. I decided to give it another go. By comparison, I could tell that it was working. I still feel tired, and certain things still make me feel sick (like strong smells and certain foods), but I am nowhere near as sick as I would be if I stopped taking it. I can totally tell if I miss a dose."

10 / 10
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  • Hal...
  • August 21, 2016

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I cannot keep water down, let alone food, if I don't take this. I was hoping it would end after the first trimester and I could stop using it daily, but I'm 4.5 months, and I still can't be without it. So grateful it's class A because I don't know how I'd work and function without it. Wishing I didn't need anything! Also, I should add... I only take half the dose: one at night and one in the morning. Two during the day is way too much; you'll feel drowsy and sedated. I learned that day one and realized I don't even need that much to alleviate the symptoms."

10 / 10
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  • Ms ...
  • Taken for less than 1 month
  • March 17, 2018

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I was afraid to take any medication, but my nausea was so bad that I was left with no choice. It didn’t seem to work the first week because I didn’t take it as prescribed, because it made me so sleepy, and I still had to work and take care of my other two kids. I buckled down and took it morning, noon, and night as prescribed. The nausea finally let up, and I felt much better, but I never really felt like myself. I was low on energy and just felt foggy. My stomach would rumble every time I ate or drank anything. I had anxiety about leaving the house because I always felt that I had to use the bathroom, but I was constipated. I listened to my body and stopped taking the medication for a few days, and I felt like myself again, energetic and clear, but that didn’t last long. Once that medicine moved out of my body, I got sick as a dog. I’m taking the pills again, but here come the side effects: insomnia, nightmares, lightheadedness, and fatigue. I hope the constipation doesn’t come back."

7 / 10
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  • 2nd...
  • Taken for 1 to 6 months
  • July 4, 2017

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "This was a lifesaver for me. I had HG with 1st and was on Zofran only, which caused a lot of constipation and cramping from not being able to go. This second pregnancy, I had HG worse than 1st and was on Zofran and Diclegis. Diclegis took about 2 weeks of taking it 3 times a day to kick in, so Zofran helped until it kicked in. Now Diclegis is all I take 4 times a day and no constipation, and I finally enjoy being pregnant. It makes me tired, but it's good for me to relax since I'm a very active person. I only need a 30-minute catnap and I'm okay. I can still easily take care of my toddler, I just lay down when she does."

10 / 10
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  • Jen...
  • Taken for 1 to 6 months
  • July 31, 2020

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "Bonjesta has been an absolute miracle lifesaver for me. This is my 5th pregnancy with horrible morning sickness 24/7. Diclegis didn't work, Unisom barely worked, and I used to take Zofran daily to function. I had to pay out of pocket for this, and it has saved me. I am still nauseous, but I can eat, drive, and function, and no more throwing up! I was sleepy for the first few days, and it takes about a week to really work, but now it's AMAZING. Highly recommend, and it's super safe!"

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 21, 2017

Diclegis (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "Absolutely improved my pregnancy experience by reducing my nausea and vomiting. I was prescribed 2 tablets before bed, 1 in the morning, and 1 mid-day because I was extremely sick. They always recommended it to be taken on an empty stomach. I only took 2 before bed with food (because I refuse to take any pill on an empty stomach), and it worked wonders. If I ever forgot to take them, I was guaranteed a horrible day."

10 / 10
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  • Mrs...
  • May 26, 2020

Bonjesta (doxylamine / pyridoxine) for Nausea/Vomiting of Pregnancy "I take one Bonjesta pill at night before bed. This medication is the only medicine that has helped with my extreme morning sickness. When I take the pill at night, I feel less nauseated in the morning. I can eat more, and I am not vomiting as much. I feel more like myself. I went from being sick 100% of the day to 20% or less some days. Definitely worked for me."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.