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Doxylamine / pyridoxine Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Doxylamine / pyridoxine Diclegis (doxylamine / pyridoxine) Bonjesta (doxylamine / pyridoxine)
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Doxylamine / pyridoxine Diclegis (doxylamine / pyridoxine) Bonjesta (doxylamine / pyridoxine)
Prescription only

Prescribed for Nausea/Vomiting of Pregnancy, Nausea/Vomiting. Doxylamine / pyridoxine may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Nausea/Vomiting of Pregnancy, Nausea/Vomiting. Diclegis may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Nausea/Vomiting of Pregnancy, Nausea/Vomiting. Bonjesta may also be used for purposes not listed in this medication guide.

More about Doxylamine / pyridoxine More about Diclegis (doxylamine / pyridoxine) More about Bonjesta (doxylamine / pyridoxine)
Ratings & Reviews

Doxylamine / pyridoxine has an average rating of 7.3 out of 10 from a total of 165 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 22% reported a negative effect.

Diclegis has an average rating of 7.0 out of 10 from a total of 116 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 24% reported a negative effect.

Bonjesta has an average rating of 7.5 out of 10 from a total of 33 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 21% reported a negative effect.

View all 165 reviews

View all 116 reviews

View all 33 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Doxylamine / pyridoxine side effects

View all Diclegis side effects

View all Bonjesta side effects
Drug Class
Generic Availability

Lower cost generic

Lower cost generic approved

No lower cost generic approved
Pricing and Coupons * Prices are without insurance
Quantity 100 delayed release tablet
Strength 10 mg-10 mg
Per unit* $2.15
Cost* $215.00

View all Doxylamine / pyridoxine prices

Quantity 100 delayed release tablet
Strength 10 mg-10 mg
Per unit* $2.88
Cost* $287.56

View all Diclegis prices

Quantity 60 tablet, extended release
Strength 20 mg-20 mg
Per unit* $12.57
Cost* $754.27

View all Bonjesta prices

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Dosage Forms
  • Oral delayed release tablet
  • Oral delayed release tablet
  • Oral tablet, extended release
Brand Names
Bonjesta, Diclegis Other doxylamine / pyridoxine brands include: Bonjesta Other doxylamine / pyridoxine brands include: Diclegis
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

12.5 hours

12.5 hours

12.5 hours
CSA Schedule 1 View glossary of CSA terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
A
Category A Studies show no risk

See the full pregnancy warnings document.
A
Category A Studies show no risk

See the full pregnancy warnings document.
A
Category A Studies show no risk

See the full pregnancy warnings document.
Drug Interactions

A total of 320 drugs are known to interact with Doxylamine / pyridoxine:

  • 19 major drug interactions (103 brand and generic names)
  • 299 moderate drug interactions (1338 brand and generic names)
  • 2 minor drug interactions (8 brand and generic names)

A total of 320 drugs are known to interact with Diclegis:

  • 19 major drug interactions (103 brand and generic names)
  • 299 moderate drug interactions (1338 brand and generic names)
  • 2 minor drug interactions (8 brand and generic names)

A total of 320 drugs are known to interact with Bonjesta:

  • 19 major drug interactions (103 brand and generic names)
  • 299 moderate drug interactions (1338 brand and generic names)
  • 2 minor drug interactions (8 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness... View more
  • Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness... View more
Disease Interactions
First Approval Date

July 30, 1956

April 08, 2013

November 07, 2016
WADA Class View classifications

N/A

N/A

N/A
More Information
Patient Resources
Professional Resources
Related Treatment Guide

1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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