Doxylamine / pyridoxine and Nausea: What Users Say

• Kar...
• May 10, 2020

For Nausea/Vomiting of Pregnancy "I started having extreme nausea and vomiting at around 6 weeks pregnant. There was a point where just thinking about food would make me nauseous. Obviously, I had to force myself to eat because of the pregnancy, but I knew it wasn't going to last, I just threw it back up. I would vomit 2 times a day and feel nauseous the whole day. My OB told me about Bonjesta, I would take anything at this point. Turns out my insurance didn't cover it, it would be $700+ out of pocket. I literally started crying because I was so tired of feeling the way I was feeling. But luckily, I got a prior approval, and immediately after taking it, I was able to keep my dinner down for the first time. I am on day 3 and currently have not thrown up or experienced nausea like I had been. It does make you really tired, but I'd rather feel tired and fight through it than be nauseous all day and have the horrible feeling of hunger but not eat from fear of throwing up."

• Mam...
• September 11, 2018

For Nausea/Vomiting of Pregnancy "I have hyperemesis gravidarum (HG)! Have had it with all 6 pregnancies. My last pregnancy (my 5th), my doctor gave me Diclegis, and it changed my whole pregnancy experience! In my previous 4 pregnancies, I suffered for 5-6 months, constantly puking, weak, fatigued, can't get out of bed, can't keep food or water down. In fact, I have been hospitalized with every pregnancy for dehydration and was admitted for 3-5 days where they pumped me up with Phenergan and Zofran (other nausea meds). I would feel a little better, but the nausea was never gone! After my first dose of Diclegis, I immediately felt a difference! Let me be clear, this is the only thing that has ever really helped take away the vomiting and nausea EVER. I've tried everything! During my 5th pregnancy, when I started taking Diclegis, it was the first time I felt relief. I am now pregnant with my 6th child, and I have started Diclegis again because at 6 weeks I'm so sick with nausea and vomiting I can't get out of bed!"

• Mar...
• Taken for less than 1 month
• April 22, 2020

For Nausea/Vomiting of Pregnancy "I am 9 weeks pregnant and have had horrible nausea and sometimes vomiting. Zofran helped, but is linked to heart defects in the babies, so I was put on Phenergan, which helped but still didn't stop the nausea, which is when my OB put me on Bonjesta. Turns out, I had no idea what nausea, dizziness, and gut-wrenching vomiting were until I started taking this medication! It made my symptoms so much worse. I've heard good things about it but want to let people know it does not work for everyone! I have settled on Phenergan, it keeps my nausea at a reasonable level, and I rarely vomit. Please stop taking Bonjesta if you're getting dizzy and sick to your stomach!"

• van...
• June 3, 2013

For Nausea/Vomiting of Pregnancy "I have always had horrible morning sickness. This time around, I am pregnant with twins, and it was much worse. I started the medication, and it stopped the ache of nausea all the time! The bad is it did stop the nausea, but I had no signs when I was going to throw up. So you randomly throw up without knowing your stomach is upset... not fun at all. The bad thing is the co-pay with my insurance was $160, so very pricey, but worth it."

• Yme...
• October 30, 2015

For Nausea/Vomiting of Pregnancy "I was completely disabled by my nausea. I had zero appetite, simple tasks seemed impossible and went 2 weeks without working. At approximately 7 weeks my doctor prescribed Diclegis. I must say I was extremely hesitant, but after another week of constant nausea, I decided I would give in. The change has been miraculous. I can sleep better, have an appetite (limited to salty or sour things only), and nausea is almost completely gone. After a few weeks of taking Diclegis, I decided to test not taking it one night and spent a full day in bed with nausea and not being able to eat. Later that night I took my 2 pills again and the next day felt absolutely wonderful. This medication is a lifesaver."

• Hum...
• Taken for 1 to 6 months
• May 17, 2019

For Nausea/Vomiting of Pregnancy "Okay, so last time I wrote a review (2019-04-25), I was just put on Diclegis, and my review might not move some people, but today, after taking it for one month, I can say, girls, if you are pregnant and you have nausea, then you deserve this medicine. Ask for samples if you want to give it a try before buying, and please, if Unisom and Vit B6 doesn’t work day one, it won’t ever work on you. I wasted two weeks on it. Also, if Reglan made you sick like it did to me, throw the pill and ask for Diclegis, and I'm sure it will help, but above all lies help of God. I thank him that I can have this medicine and be happily pregnant."

• Bri...
• Taken for 1 to 6 months
• December 16, 2017

For Nausea/Vomiting of Pregnancy "So I suffer from hyperemesis gravidarum (HG) (severe nausea and vomiting). I was prescribed Zofran with my first pregnancy, and the birth defects that were listed that could affect my baby affected my baby. I was so angry and upset with my doctor for telling me it was safe to take. My daughter now has a heart defect. Second pregnancy, I suffered so much more than my first. I found a new OBGYN, and he prescribed me Diclegis. I will say this: it’s a lifesaver. I was vomiting 20-25 times a day, and the nausea never went away. I couldn't drink or eat anything, I lost 15 lbs in 3 weeks. This drug is the only thing that is safe during pregnancy, and it was the only drug that works. I would only recommend this to anyone that suffers from HG."

• Aly...
• May 3, 2019

For Nausea/Vomiting of Pregnancy "Bonjesta helped immediately. After dealing with nausea and vomiting starting at week 5, I realized it would have been impossible to get myself out of bed and into work. I wasn’t able to keep water down. Was dehydrated. Weak. My doctor prescribed this immediately, and it got rid of probably 90% of the nausea and vomiting."

• My...
• Taken for less than 1 month
• August 15, 2017

For Nausea/Vomiting of Pregnancy "This drug has saved me from going insane because of how ill I was. I suffered from severe nausea and vomiting in pregnancy. Throwing up for weeks on end, I would throw up every few hours. I went days without being able to keep anything down, including water. Those who suffer from NVP, I know your suffering... it is so awful! I was stuck on the couch and in bed for over a month, and then I finally decided it was time to go on medicine. My quality of life was 0 before this medication. This medicine is definitely on the spendier side but worth every penny if you are suffering. If this medication didn't exist, I would no doubt be in the hospital."

• jbe...
• Taken for less than 1 month
• July 25, 2018

For Nausea/Vomiting of Pregnancy "At first, I hated how drowsy this medication made me. The first dose, which I took at 9 p.m., knocked me out until around 3 p.m. the next day. But slowly, my downtime started to decrease more and more. Last night, I took it and went straight to bed around 10, and I woke up around 9:45. So that's improvement. I think it's worth it to keep taking it and seeing if your body gets used to the drowsiness because honestly, for me, it really helps with the nausea. Some days it's just barely there, others, it is almost non-existent. It totally makes morning sickness more bearable for me."

• Anonymous
• January 16, 2019

For Nausea/Vomiting of Pregnancy "This medication was a lifesaver. I went to the ER twice with dehydration from severe vomiting. I couldn’t keep any food or water down. I was diagnosed with HG and sent home with a prescription for Diclegis and Zofran. I did not take the Zofran, but took the Diclegis religiously. It didn’t stop me from feeling ill right away, but it took the edge off and I could continue to work. I was still nauseous but able to eat again. After a month on the medicine, I was gaining weight (after having lost 15 lbs of prepregnancy weight), and I was eating like a champ! Yes, this medicine does make you EXTREMELY tired, but I’d rather fight the day tired than throwing up. (25 weeks and still taking it because I’m still sick)"

• Pas...
• June 21, 2016

For Nausea/Vomiting of Pregnancy "I have always been sick with each pregnancy and was put on Zofran. It worked sometimes. I have been taking Diclegis for about a month, and it works the same as Zofran for me. Sometimes it works, other times it doesn't. I am up to four pills per day. Sometimes I still throw up and feel nauseous - like today. I guess the best thing for me is to get my tubes tied. I can't deal with this whole pregnancy thing ever again. I know one thing for sure: this is the very last pregnancy for me."

• Hou...
• Taken for 1 to 6 months
• May 17, 2015

For Nausea/Vomiting of Pregnancy "I am thirteen weeks pregnant and have been taking this medicine since 6 weeks. At first, I didn't notice any difference, but one day my nausea disappeared. Completely! I thought that the medicine had nothing to do with it since I was sick for two weeks while taking it. Three times I have forgotten to take it and spent the following day puking. This medicine has given me my life back. I have two younger kids at home, and I don't have the time to be sick."

• Bar...
• January 18, 2017

For Nausea/Vomiting of Pregnancy "This is my 4th pregnancy. I've always had bad morning sickness with each pregnancy but always ended by my 10th week. I started the Rx at 7 weeks and tried stopping at 13 weeks but experience terrible withdrawal symptoms. I only take 1 pill at night. When I tried stopping the med, I violently threw up, nauseous all day, body aches, and excessive sweating. I would have never started the prescription if I knew stopping it was this painful."

• Cou...
• Taken for 1 to 6 months
• November 15, 2018

For Nausea/Vomiting of Pregnancy "Came into severe morning sickness at 6th week of my 1st pregnancy. Lost my appetite; nauseous all day, every day. Nights were the worst because I would wake up every 20 minutes, feeling like I needed to vomit. I lost weight. I tried homeopathic remedies. Nothing worked. I was so worried that I would have to live like this for my whole pregnancy. My doctor prescribed Bonjesta. Within 20 minutes of taking the first pill, I felt drowsy, but my nausea already started subsiding. I will take drowsiness over nausea any day. I have to work hard to stay focused, but still, I am able to work and function and eat. I highly recommend Bonjesta. I still experience mild nausea from time to time, but nothing like before. I take 1 pill when I wake up in the AM, plus 1 pill at approximately 6:30 PM."

• Muf...
• Taken for 1 to 6 months
• August 17, 2019

For Nausea/Vomiting of Pregnancy "I suffered from very bad hyperemesis gravidarum (morning sickness) in my first pregnancy and had success in relieving symptoms with Diclegis. During my second pregnancy, I ended up having morning sickness again and was desperate for relief. My doctor prescribed me Bonjesta, which at first appeared to relieve symptoms, but within two days I was just as sick as before. I ended up having to eliminate so many foods that, by the time I was done, I was only able to eat spinach and potatoes that were steamed. I decided to drop the Bonjesta and see what happened, and within two days I had zero symptoms and was able to eat whatever I wanted. Imagine that, the anti-nausea drug was causing my issues all along. This medication did not work for me at all. I’m glad that my insurance covered the medication because I would have been pretty sour about having to pay the exorbitant cost."

• Cha...
• August 12, 2016

For Nausea/Vomiting of Pregnancy "I was prescribed this medicine for my morning sickness. I haven't been able to get out of bed since I found out I was 6 weeks pregnant. This medicine does help me to not feel nauseous, but the side effects are terrible. I feel as if I've been given a heavy sedative. I started with the prescribed dose of two pills at bedtime. When I woke up the following day, I could barely lift my head off the pillow and was in and out of strange drug-induced sleep all day. I tried taking the medication again but only taking one pill. The effects were the same, and I felt like I was on heavy drugs. I tried for a third time but only a half pill. Same outcome. Can't get out of bed, foggy, and in and out of sleep."

• 2nd...
• Taken for less than 1 month
• August 24, 2014

For Nausea/Vomiting of Pregnancy "I'm 4 months along with my second child. This pregnancy is very different from the last. I never had such bad nausea, vomiting, and dry heaving. I'm taking this medicine on an as-needed basis. So far, I need one pill at night and another about mid-morning. The original prescription said one in the morning, one in the midday, and two at night. I did that once and slept until 2 PM the next day. That's not healthy either. The only complaint I have is the cost. It ran $178.53 for us. A cost that wasn't expected, but when Phenergan and Zofran aren't working.... you give in. Just as every OTC or prescription, there are side effects. For me, the benefit outweighs the risk. Try to stay away from medication until at least 13 weeks."

• Col...
• August 3, 2015

For Nausea/Vomiting of Pregnancy "I lost 15 lbs due to nausea and vomiting since my 7th week of pregnancy. I was vehemently against taking any medication, but after I researched this medication, I felt that it was as safe as a medication can be during pregnancy. I was at risk of losing my baby due to the significant weight loss, so I am grateful for this safe, completely effective medication. It is working for me at the lowest dose, and I feel I should buy stock in the company selling this wonderful drug. I am able to eat, drink, and maintain a normal lifestyle after weeks of misery. I highly recommend this drug if the traditional methods of managing NVP are not effective for you. I was lucky enough to receive samples from my OBGYN, so I cannot say anything as to cost."

• Pre...
• Taken for less than 1 month
• January 20, 2021

For Nausea/Vomiting of Pregnancy "Well, I came to the comments hoping it wasn’t just me, haha! I started Bonjesta at 13 weeks, and honestly, I passed out the first night (can’t have nausea if you’re knocked out), so now I’m on day 4. It doesn’t put me out, but it’s like it amped it up. I’ve thrown up 3-4 times a day, and as soon as I put food on my tongue, I get gaggy and chills and end up not eating. I’ve been living on crackers and chips, then I throw those up. I tried a smoothie yesterday and ended up puking it all back up. Please tell me it’s almost over, lol."

• Ala...
• Taken for 1 to 6 months
• February 1, 2016

For Nausea/Vomiting of Pregnancy "I had morning sickness since I was 8 weeks pregnant. I had my first ObGyn visit at 12 weeks. In 4 weeks, I lost 11 lbs. :-( I felt miserable. I did not know there was medication to prevent nausea. My doctor prescribed Diclegis. I started 2 pills before sleeping, 1 pill in the morning, and another in the afternoon. It was magic and amazing. When I reached 20 weeks, I started feeling sick again, nauseous and dizzy, and shaking. I thought maybe I was doing overdose. I went down to 1 pill at night to sleep and I feel GREAT ALL DAY!!! Amazing... And I am currently 26 weeks and I still use it because I skipped one day and I felt horrible. Tip: if you skip or miss a pill at night, take one at any time and you will feel better. I love Diclegis."

• SSa...
• Taken for 1 to 6 months
• May 3, 2020

For Nausea/Vomiting of Pregnancy "When I was around 6 weeks pregnant, I was vomiting NONSTOP. It got to the point where I could not even hold down water. The doctor prescribed me Diclegis, and it has been a MIRACLE drug. I take two tablets at night before I go to bed (caution that it does make you very sleepy), which I find an added perk because it helps me get a full night's rest. There are some mornings where I wake up still feeling slightly nauseous, but I am not vomiting, so the occasional slight nausea I can deal with. If you’re looking for something to make the 1st trimester nausea/vomiting disappear (or almost disappear), look no further because this is the drug for you."

• Lyn...
• September 8, 2015

For Nausea/Vomiting of Pregnancy "I have been so sick since becoming pregnant, vomiting several times per day. Initially, I was given Zofran, but the minute it would wear off, I'd start vomiting again. My doctor switched me to Diclegis a few days ago and I feel great! No vomiting, no nausea, and I'm not worried about the potential problems that extended use of Zofran could cause anymore."

• Bec...
• Taken for 1 to 6 months
• January 23, 2020

For Nausea/Vomiting of Pregnancy "I had pretty bad morning sickness starting around my 6th week of pregnancy. I got to where I dreaded waking up the next day because I knew I’d be super nauseous and sometimes vomit. At my first appointment at 8 weeks, I told the doctor I was experiencing nausea and vomiting, and he prescribed me this, and it’s an absolute godsend! Taken at bedtime, I felt much better the next day! You don’t have to worry about this drug because all it is is a high dosage of Vitamin B6 and Unisom. I’m now 27 weeks and still taking it every night because I’ve been feeling good and am scared to stop it and be sick again! Lol. I tried stopping it early in the 2nd trimester but promptly vomited throughout the day, so I plan on continuing to take it because my doctor said it is safe to do so."

• Fir...
• Taken for less than 1 month
• July 16, 2015

For Nausea/Vomiting of Pregnancy "I have been taking Diclegis for 2 weeks now, and I feel amazing. Taking 3 pills a day seems to be the magic dose for me. I previously tried Zofran, which helped minimally, but I was still nauseous and vomiting violently a few times throughout the day. I work full time, so I really needed something more effective, so my doctor recommended I try Diclegis. Two thumbs up, just a little pricey."