Clomipramine User Reviews & Ratings (Page 5)

• Toona
• Taken for 1 to 6 months
• April 14, 2015

For Depression "I had several attacks of depression in the last 25 years following stress at work with variable severity. All of these attacks respond well to Anafranil in 3-5 weeks of therapy with some side effects like sweating and tremor during the first 2 weeks. Then I take a small dose for another several weeks and tapering it without problems. During the last attack of depression, I made a mistake when I started treatment with Zoloft, depending on the opinion of a psychiatrist who said to me that this drug is very good with fewer side effects in comparison with the 'old drug Anafranil with unpleasant side effects,' as he said. I'm on Zoloft with up to 150 mg for the last 6 weeks without significant improvement. I decided to stop this drug and return to my Anafranil."

• headh...
• November 17, 2010

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Works well for OCD, wonderful for body pain, and moderate for depression (it takes 6-8 weeks for me to see any effect), but the side effects are not pleasant: dry mouth, fatigue, drowsiness, difficulty concentrating, and anorgasmia."

• BeFree
• Taken for 1 to 6 months
• August 8, 2020

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I took Anafranil for 5 months at a dose of 25mgs. Definitely took some power away from the intrusive thoughts but not fully. Had a hard time with being tired in the morning, terrible dreams, mild consultation. On a positive note I did not gain any weight and was able to workout regularly. Tried to go up to 50mg but that got rid of my libido. Felt like taking an upper and downer at the same time. Some of the time I felt good, other times I felt depressed. Unfortunately, couldn’t tolerate a higher dose. But if you really need to shut off the noise this may be the way to go. Best of luck."

• Cali...
• April 13, 2009

Anafranil (clomipramine) for Obsessive Compulsive Disorder "From reading the medical literature, this is probably the most effective treatment for obsessive-compulsive disorder, but the side effects led me to change. After a year of use, I switched to a less taxing medication. The weight gain was too much, and it made me more confrontational with others. However, for bringing my initial problem down to a manageable level before switching, Anafranil was a lifesaver."

• vmrdoug
• Taken for 10 years or more
• September 7, 2016

For Panic Disorder "I have had anxiety and depression since childhood and self-medicated with alcohol and street drugs. I got sober 29 years ago, but after being sober for 2 years, I had a nervous breakdown. My doctor put me on Xanax and Clomipramine, I got better. Years passed, and I have had setbacks, and doctors prescribed all SSRIs and continued to increase benzodiazepines to an unsafe level. The doctors took me off the benzodiazepines and Clomipramine. My anxiety and depression have returned. I went back to my Clomipramine a week ago, and I already have my life back."

• Muzz
• Taken for 1 to 6 months
• December 22, 2019

For Obsessive Compulsive Disorder "I started using this drug clomipramine 5 weeks ago , I had been on lexapro which didn't help . After 3 months my doctor put me on clomipramine as he diagnosed me with OCD. I had bad anxiety depression and major intrusive thoughts continuously all day long. I'm now up to 100mg four tablets at night just before bed , I also have to use sleeping tablets to get to sleep at the moment but the intrusive thoughts have calmed down a lot. In the mornings I wake up a little tired. I get mild constipation and dry mouth. Is 100mg too big of a dose? Also is it best to take this medication at night or morning ? How long does it take to get the full benefit on this medication . Muzz "

• Enjoy...
• Taken for 1 to 6 months
• January 21, 2017

For Panic Disorder "Anafranil is really a wonderful drug. It helps people like me who have generalized anxiety and obsessions. Before this, I used Lexapro, it also did help but not that much and took longer, like about 5-6 weeks, to benefit from it. However, with Anafranil, it took only about one week to 10 days to feel positive results, which made me much calmer and saved me from terrible morning anxiety attacks. I only used 50 mg, and now I've been using 75 mg, and I felt great! Yes, side effects, especially sexual dysfunction, upset me, but it rather turned out to be delayed ejaculation, which is not so bad, especially for my partner. :) To cut a long story short, I really advise you to try this medication if you didn't have relief from SSRIs."

• Sam
• Taken for 6 months to 1 year
• March 19, 2021

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Anafranil helped my OCD symptoms a little bit and helped me sleep at night. However, as my doctor increased my dosage, I started gaining weight, having horrible acne, and SEVERE constipation. It also made me crave junk food like some kind of addict. I was on Anafranil for about 10 months and gained 40 lbs. I haven't taken Anafranil in about 8 months. I've lost the 40 lbs. I didn't have to go on a diet or anything, as soon as I was off the drug my appetite went back to normal. However, 8 months later and my colon is still not healthy. I still have major issues with constipation and bloating. My doctor had me try Zyliss, a drug for IBS, and it helps a little. I feel like Anafranil may have ruined my gut. I have a hard time leaving the house because I am so uncomfortable in my gut. I wish I had never taken this drug. I was much better off before."

• Adyy
• Taken for 1 to 2 years
• May 30, 2015

For Depression "I had roller coaster episodes of depression that did not seem to be cured from multiple SSRIs that I tried. I'm struggling against depression for 6 years. The only miracle drug that worked is only clomipramine. Whenever I feel depression, I just have to adjust its dose, and it starts working again."

• balance...
• Taken for 5 to 10 years
• November 18, 2022

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Anafranil gave me very serious balance problem. Within days of it for OCD I began stumbling up the subway steps. The psychiatrist assured me it could not be from the anafranil. Over a period of a few years I twice fell and had to be treated and receive facial stitches in the emergency room, lost part of a front tooth, suddenly fell for no apparent reason walking down the street, climbing stairs, going down stairs. I could have had extreme injuries, or in the case of falling down 15 steps at the train station died. I asked my psychiatrist about anafranil causing the falls. He said it would not in any way have caused these falls. On reporting my falling to an audiologist she told me that research shows that anafranil indeed does lead to balance problems in 30% of people taking it."

• Phishie
• Taken for less than 1 month
• January 5, 2023

Anafranil (clomipramine) for Obsessive Compulsive Disorder "So far I have been on 25 mg for about 2 weeks. It has given me much more headspace than other antidepressants I've tried so far. Sometimes I can now redirect my attention and not fixate on the thoughts. Obsessive thoughts do still come though, but I need to put in the work in ERP anyways. I am having good hopes for increasing the dose now. Only issue is it makes me really constipated right now. But compared to every other antidepressant, I believe this is one of the best for OCD."

• Emano
• Taken for 1 to 2 years
• March 27, 2019

For Obsessive Compulsive Disorder "This drug has completely changed my life. I’m now 28 and have been suffering with OCD since I was a young child. I wasn’t prescribed anything until I was 18 and shifted through medications until I had a complete breakdown at 26. I was prescribed clomipramine by a psychiatrist for my OCD and while it took many weeks to take full effect, I’m so thankful I stuck out the process. The side effects at first were not so nice but looking back, it was NOTHING in comparison to the mental anguish of OCD. I highly recommend giving clomiptrmine a try if you’ve been prescribed it for OCD. I obviously still have occasional intrusive thoughts but they are much much easier to brush off now. I actually go through my day with maybe only five compulsions as opposed to the hundreds (not joking) I used to have."

• Shaed...
• August 31, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I was on Effexor for 3 months and I really liked it besides the fact it didn't help with my obsessive/intrusive thoughts. I did quiet a bit of research on medications and decided to ask my doctor if I could try Anafranil. I have been on Anafranil for a month now and it has really helped with the obsessing over intrusive meaningless thoughts. In the beginning it did spike my anxiety which I used a benzodiazepine to help with that until the anxiety calmed down. After that, I noticed I started to feel dizzy when I stood up fast and it was another side effect. At this point I began to get nervous but I heard so much good reviews about this drug I really wanted it to work. After making it through my first month with it, the side effects began to lessen."

• Infamy
• Taken for 1 to 6 months
• July 30, 2022

Anafranil (clomipramine) for Obsessive Compulsive Disorder "My experience with anafranil over the past 3 months is as follows: SEVERLEY chronic constipation, urinary retention that hospitalised me the other day, a 60 percent increase in my depression, a 90% increase in my overall anxiety and at best a 15% decrease in my OCD symptoms. Not to mention the sexual dysfunction that includes painful orgasms and low libido, and then there's the constant dry mouth. I cannot for the life of me recommend this medication to anyone. I'm currently 5 days away from discontinuing this medication and replacing it with prozac."

• Samo
• Taken for 2 to 5 years
• February 1, 2021

For Depression "Awesome drug!! After trying almost all SSRI with no improvement at all. then the combination of mixing anafranil and lithium (I'm not bipolar) worked wonders for my depression. Have been on it for a couple of years now and still great. However sadly did not notice its full effects until probably 6 months. Felt pretty yuk for the first 6 weeks...but then slowly got better and about 12 months felt great. When nothing else worked it pretty much saved my life!"

• Anonymous
• January 23, 2012

Anafranil (clomipramine) for Obsessive Compulsive Disorder "After trying a few different medicines (with no benefits) my doctor pulled out the big guns and gave me Clomipramine. I have severe OCD but the purely obsessional (intrusive thoughts). I used to be a checker and handwasher though. I took it for over 1 year, Unfortunately Clomipromine did nothing for me on 250 mg, which is pretty much the highest dose you can take. I did not have alot of side effects except dry mouth when I was on it. I quit taking it after I ran out on a holiday weekend and saw the withdrawal symptoms, severe nausea. And even when tapering slowly off it over the course of months I still had terrible withdrawals (vomiting and nausea). "

• OCD
• February 3, 2017

For Obsessive Compulsive Disorder "I've been taking Clomipramine for a year now. I started at 200mg and went quickly up to 300mg (the max you can take). It gives me a very dry mouth and constipation. Also remember that this drug needs to be given in very high dosages to work (200mg-300mg). If a doctor just gives you 10 or 50mg, it's not going to work. Also, this is an older drug, you likely will have to ask for it by name. I have pure Obsessive disorder (no compulsions), and tried Prozac before this with no success. A few days on this and I noticed a big difference. I've been maintaining on 300mg for a year now. I don't like the side effects, but I won't go off of it, because it's been an amazing drug that works for me. It took away about 90% and now I can easily manage what's left"

• Anonymous
• March 5, 2013

For Obsessive Compulsive Disorder "I had suffered debilitating OCD from the age of six, and Clomipramine has improved my condition 95%. It also handles my chronic sciatica beautifully. Diminishes pain by about 70%! Constipation and sweating are my only side effects. And that's not much of a problem. I'm 45 and finally enjoy life."

• User
• Taken for 1 to 2 years
• August 12, 2018

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I definitely recommend Anafranil to anyone suffering from moderate to severe OCD. While on this medication I noticed a great reduction in my OCD symptoms and it had elevated my mood even. Though a few of this medication's side effects might be a little troublesome, generally you get used to it and it isn't life changing."

• Anonymous
• March 11, 2024

For Panic Disorder "I am leaving this here for anyone who has been prescribed clomipramine for anxiety. Please give this drug a good try. It really works! I am only on 50mg and it helps calm down my obsessive thoughts. It also improves my mood. I take it alongside 20mg of escitalopram and the two work well together! If you have tried pregabalin for anxiety and can't tolerate it then ask your doctor if you can try clomipramine for anxiety. When I first started it I suffered from mild insomnia but now I am fine! I do have a dry mouth but other than that I have no other side effects. I take one pill at night. Please also invest in seeing a psychiatrist if you are suffering from crippling anxiety. Being treated properly can be life changing! Good luck everyone."

• Marys...
• Taken for 1 to 6 months
• September 2, 2015

For Obsessive Compulsive Disorder "I have been taking this drug for almost 3 months. It has helped significantly with intrusive thoughts and therefore decreased compulsions and being stuck on rituals. More than significant, actually. It is saving me and I'm able to function better. The problem is I've gained 13 pounds. My hunger is never satisfied! It is always on my mind. I know my mental health is worth gaining SOME weight; however it shows no stopping. I am not a thin woman, gaining too much weight makes me unhappy in terms of how I look. I have some joint problems too. Thanks for listening. I do not plan on quitting this med for as I said, works great."

• Dano
• Taken for 1 to 2 years
• November 30, 2019

For Obsessive Compulsive Disorder "I’m 44. Have been living with terrible obsessive thoughts my whole life. Yes, I have depression and anxiety, but even when I felt “happy” and “free” from those, the thoughts wouldn’t stop. I thought I was just a negative person. Started researching and asked my dr if I could try Anafranil. Best decision I ever made. The thoughts were almost gone! Then I switched jobs and had to wait for new insurance to kick in. Anafranil was about $1100 without insurance. I’m about to start again. The only thing I hate is the terrible dry mouth. Otherwise it’s amazing!"

• Mr Jo...
• March 9, 2016

For Obsessive Compulsive Disorder "Clomipramine began improving my OCD symptoms within a couple of weeks and seems to have all but eliminated my intrusive, repletetive thinking at this point. I still have off-days from time to time, but my therapist and doc both agree that's to be expected. This stuff has taken me from not being able to function to getting back to my life. The only downside is I have experienced some difficulty reaching orgasm. Not every time, but from time to time. Erections are fine and libido is actually increased - due to just feeling so much better. All in all that's a small price to pay for what feels like a restoration of my basic sanity."

• tt8967
• Taken for 1 to 6 months
• June 17, 2024

"I have a sound sensitivity disorder (hyperacusis). A pharmacist recommended that I give clomipramine a try. I increased the dose slowly to 200 mg. It has been working! Most of my ear pain is gone, and I can hear loud sounds without getting worse hyperacusis. I still have some degree of sound sensitivity, but it has improved quite a bit. I am going to continue taking this drug for at least six months. I don't know if there is any research on hyperacusis and clomipramine yet, so it is definitely an off-label use. I know I am not the only one who has gotten improvements in hyperacusis from this drug... if you have hyperacusis, I urge you to give this a try and see if it works for you also."

• wil
• Taken for less than 1 month
• July 24, 2018

Anafranil (clomipramine) for Panic Disorder "I was suffering from anxiety and was prescribed anafranil by my GP. Over a period of about a week my anxiety increased to the point that I was not well enough to go into work. I contacted my GP who increased the dosage. Within a few days I became so anxious I was unable to leave the house. I also suffered shaking and felt so weak that I stayed in bed. But worst of all I started having suicidal thoughts. At this point another GP from the practice called out to see me at home and took me off anafranil and onto a short term course of diazepam/temazapam. My situation improved and stabilised. In the longer term I was prescribed venlafaxine which helped with my condition. If you start having any suicidal thoughts ring someone immediately!"