Clomipramine User Reviews & Ratings (Page 3)

• Jillay
• November 12, 2015

Anafranil (clomipramine) for Panic Disorder "I was suffering panic attacks, anxiety, depression, and irritable bowel syndrome. I started on half of a 75 mg for two weeks and then a full tablet. The side effects were a bit of a challenge some days, but the upside was I had good days very early into taking. I started them four weeks ago and panic attacks are gone, minimal anxiety now, depression lifted considerably, also no more IBS. One thing that no tablet cannot do is change how you think. I am very, very blessed!"

• nasca...
• January 1, 2012

For Panic Disorder "I suffered with panic attacks, depression, and obsessive-compulsive disorder for many years. Finally, I tried Anafranil (only 25 mg) and it was my miracle. I have been on it for almost 30 years. I have not suffered any side effects and have not had to increase the dosage. I HIGHLY recommend suggesting this medicine to your doctor if you have any of the problems. This literally saved my life."

• Bobby...
• Taken for 10 years or more
• August 20, 2019

For Obsessive Compulsive Disorder "Anafranil or Clomipramine has completely changed my life. I have been taking it for over 25 years (I'm 51) and wish I started it 25 years sooner! It started to ease my OCD symptoms almost immediately. I was first given several SSRIs and could not take the side effects - they made my OCD much worse. Don't settle for the medication of the month or what your doc has seen work in the past. Everyone's brain chemistry is different, and just because Clomipramine is old does not mean it's ineffective. I also have adult ADD. My meds for that have not proven to cause any problems with the Clomipramine. Best wishes to all sufferers."

• Juliet...
• Taken for 1 to 6 months
• June 8, 2023

For Panic Disorder "Had life debilitating panic attacks after my mum died. I couldn’t work or socialize and felt like I was dying too, was so awful. After a couple of weeks on this drug, I started to get my life back, and now 4 months in I feel so good. Only wish I’d been prescribed this years ago as OCD has affected me all my life. Side Effects? A few (tiredness, hot sweats, and a dry mouth - but only in the first few weeks, now all gone). Honestly, this drug has been a lifesaver."

• Nate
• Taken for 1 to 6 months
• April 10, 2019

For Depression "I've tried many SSRIs and SNRIs with little help, with augmentations of all sorts. Clomipramine is the only drug that has worked well so far for my depression. I did a combo of rTMS and clomipramine at 100 mg. Now, I am finally pulling free from the grips of severe clinical depression. Thank you, clomipramine!"

• K_M
• Taken for 1 to 6 months
• September 4, 2020

For Panic Disorder "Have suffered from a lot of Anxiety, Panic, and Depression as well as few unwanted thoughts and feelings from 6 years.....!! Tried all SSRIs, SNRIs, Anti-psychotics and Two TCAs(Imipramine, Amitryptyline), none of them can bring satisfying response!! But Clomipramine did!! Difference of Day and Night just inside 7 days!! No major Side effects, only minor one in starting days !! Dose: 50mg in night/daily!!"

• Anonymous
• March 21, 2012

Anafranil (clomipramine) for Obsessive Compulsive Disorder "After three years on different antipsychotics, I started taking this finally to some relief. I have been taking it now for about six months. It is still working well for obsessing, but the side effects are starting to add up. I have steadily gained weight. Severe dry mouth at first, not so bad now though. Total anorgasmia fixed by Viagra, and uncontrolled twitching. It sounds bad when I write it down but compared to the antipsychotics it's much better. I still feel better than I have and so much happier."

• Man...
• Taken for 1 to 2 years
• September 10, 2017

Anafranil (clomipramine) for Depression "Was on Effexor, Seroquel, and Prothiaden but could not shift the constant thoughts of killing myself. Driving became a nightmare, just leaving the house was impossible as my thoughts kept telling me to walk in front of a bus, etc., etc. Anafranil literally saved my life and gave me back the wish to live. Most effective drug I have ever used, and gradual withdrawal worked really well. Thoughts not completely gone but no pressure anymore, they just drive on by."

• Anonymous
• October 5, 2011

Anafranil (clomipramine) for Obsessive Compulsive Disorder "My obsessive compulsive disorder has improved significantly. It has also helped with depression, but I just upped my dose from 150mg to 225mg to see if I can get more of an antidepressant effect. Almost no side effects. I take it in the morning and I do not feel sleepy. Anger and irritability have improved significantly as well. For those who share in the future, let me know how much you take, please. It helps."

• Brianne
• Taken for 1 to 2 years
• July 25, 2024

For Obsessive Compulsive Disorder "Saved my life. My OCD has always caused vulgar and aggressive intrusive thoughts, they became so potent that I nearly checked myself into an early grave. The only side effect I had when starting was that it made my sleep a bit lighter, so I woke easier. I haven’t known silence like this from my intrusive thoughts in all my life. I can breathe again."

• Anonymous
• February 15, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I began taking this drug in 1990. It gave me my life back. I have taken it for 27 years, and it still works for me. For me, the side effects are worth enduring. I also take Buspar twice a day for these 27 years."

• Nols
• Taken for less than 1 month
• September 13, 2014

For Obsessive Compulsive Disorder "I have been on this medication a short time. Apart from drowsiness which I'm still adjusting to, I am finding it really helpful. After being on many other medications over the years, I am finding that Clomipramine mixed with my others has finally reduced the pit of anxiety plus the intrusive and obsessive thoughts that I tend to have continually. For the first time I feel like I can overcome the anxiety plus not be troubled by thoughts that I cannot control. I was SO tired of people just telling me I needed to control my thoughts and could overcome them if I wanted. Hey, I'm in my 50s and hasn't been possible up until now! Anyway, so far so good. The drowsiness is a bit troublesome, but to be honest, nowhere near as troublesome as problems."

• Anonymous
• July 19, 2010

Anafranil (clomipramine) for Irritable Bowel Syndrome "Before taking Anafranil, I had severe episodes of Irritable Bowel Syndrome diarrhea. I had anxiety which gave me diarrhea, and that fear of diarrhea gave me anxiety. It was a vicious circle. I even had an 'accident'. I was prescribed Anafranil (75mg, then I lowered the dose to 50mg) and it was definitely a life-saver. No more anxiety and no more diarrhea. I could eat everything I wanted. I was able to go on vacation, have a girlfriend, go to the mall, go to parties, have a normal teenage life, and not wonder every time if there is a bathroom near. For sure, there are some typical tricyclic antidepressant side effects, but I prefer to have them than having anxiety and diarrhea. You have to make a choice and find the right dosage for you."

• zahi
• December 10, 2014

For Depression "I use this medication for 5 years after I tried everything Prozac, Cymbalta, Abilify, and all the others. This one was the only one that worked. It took 1 month to feel good and continued to grow for 1 year. It is not like the other medicine that lets you continue in your life, but you still don't feel good. This medicine really makes you strong and without all the bad thoughts and the lack of energy."

• marko
• Taken for 6 months to 1 year
• June 14, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "After a long 12 years of being on Effexor XR, my anxiety OCD was beginning to get worse. My GP felt it necessary to increase my Effexor to 150 mg, and although I had done that in the past, Effexor was just not working anymore and actually began working against me. Awful anxiety at nighttime and my OCD ('I have pure-O'), and I felt I couldn't get things under control. I had enough, and it was time for a change. I saw a different GP who was knowledgeable about anxiety, and he switched me to clomipramine/Anafranil 50 mg to start. I only had a few bad days from the initial switch because Effexor can be nasty to come off, but then my life came back, and I feel great! Just remember nothing will rid you of OCD, but this med is great to manage it!"

• Luahna
• Taken for 1 to 6 months
• January 18, 2013

Anafranil (clomipramine) for Obsessive Compulsive Disorder "This drug was a miracle for me! My problem was that I was always late for any and every little thing I attempted to do, and it was ruining my life. It is very baffling for me because I started with only 25 mg, and within four days, I was automatically, not just on time, but early for everything, without any thought or effort! I was ecstatic. This phase lasted 3 weeks. The doc said I'd be a superwoman when she amped me up to 50 mg. Well, that made it stop working! I began to slowly regress, and then started to be extremely drowsy to the point of even falling asleep at the wheel -- and worse, it wasn't even working! We experimented with it, but it never worked again, and I am super sad about that."

• Megg
• December 28, 2016

For Depression "I've been on over 6 SSRIs along with the combination of benzodiazepines over the past 7 years for the treatment of depression, PTSD, OCD. Nothing has been so life-changing and effective as clomipramine. It's the most expensive prescription I've had ($40/mo), but it's also the most helpful. I noticed the benefits within 2 weeks, with its effects continuing to increase over time. I've been able to wean off of the benzo, and my anxiety has stayed at a manageable level. My OCD has subsided immensely, but more importantly, this medication helped pull me out of a deep depression I had been stuck in for years. I couldn't be more grateful that my psychologist had the idea to try this medication, as I hear it is an older drug. TRY IT! :)"

• Anonymous
• September 22, 2009

Anafranil (clomipramine) for Obsessive Compulsive Disorder "After taking this medicine, I woke up one morning to realize that I felt connected to the world, and when I started to do my rituals, I realized that I just didn't need to. Amazing. The problem was that I gained 40 pounds, and the high dosage, necessary (over 200), scared me. I would recommend that a person try it and see if a lower dosage will work for them. If so, it's a miracle."

• Anonymous
• August 20, 2010

Anafranil (clomipramine) for Obsessive Compulsive Disorder "Ever since I was ten years old, I have had intrusive images of inflicting pain and suffering on myself and others. These images create emotional turmoil in life because obviously I don't want these thoughts. I've tried different medications, yet Anafranil seemed to work the best. My intrusive thoughts went away almost completely, granted I was on the highest dose. However, Anafranil had consequences: it gave me irregular heartbeats and heart palpitations to the point where I felt like I was having a heart attack. I had to wean off the medication because of this. This was distressing to me because Anafranil made me emotionally feel like a million bucks, but physically made me feel dumpy."

• Charmed
• Taken for 1 to 6 months
• June 13, 2019

For Depression "This is a VERY effective Rx; it totally cured my depression and repetitive thinking, but is the polar opposite of imipramine and amitriptyline in side effects. The others were sedating, increased my appetite, and decimated my memory. Clomipramine decreased my appetite and gave me tons of energy. My outlook changed 180 degrees. It may increase anxiety for some, but made me feel so well and happy that I wasn’t worried about anything (not that I didn’t care or was catatonic as on imipramine). I’m no longer always obsessing about the minutiae to the point of being impossible to live with; fear no longer motivates me. This could make someone who is bipolar (last reviewer) more manic and takes a while to adjust your sleep pattern to, but this prescription is a godsend. I’ve been on and off antidepressants for 35 years. I wish I had found it sooner. If the other TCAs made you slow or confused, have weird skin problems, rashes or acne, try this."

• saved...
• Taken for 1 to 6 months
• May 14, 2015

For Obsessive Compulsive Disorder "I'm a 26-year-old male with one child and another on the way. I suffer from GAD and OCD. My doctor prescribed me sertraline about six months ago when it got out of control. This did nothing but increase my symptoms to the point where I almost had to leave work and go into mental health care. I then got put on to a specialist psychiatrist, who put me on clomipramine antidepressants and quetiapine antipsychotics. This, along with CBT, has almost cured me. I am 90% normal again, just in time for my new baby boy to arrive and for me to be a good father. I 100% recommend this mix of drugs and therapy."

• Ivory
• Taken for 1 to 6 months
• October 2, 2022

For Obsessive Compulsive Disorder "I was on Paxil for a decade and it slowly started losing its effect. After suffering from panic attacks I realised it had stopped working. From that moment I tried everything, none of it worked. I tried mirtazapine, Wellbutrin, fluoxetine, citalopram, and pregablin. You can imagine how I felt I would never feel ok ever again as each medication failed to work after months of trying. The doctors in the UK told me there was nothing else they could try, and I was in a very dark place. I contacted another doctor who said Clomipromine was their last ditch attempt at helping me (not a great way of saying it but oh well). Within the first week I felt like a new person. I actually feel quite emotional writing this. My panic attacks are gone, my racing thoughts and spiralling are basically over. I can just let them go and that’s that! I used to not be able to be alone with my own thoughts because I would have a panic attack from them. Now I feel HAPPY and have ENERGY."

• Vee
• January 12, 2015

For Obsessive Compulsive Disorder "This medication, paired with a small dose of Celexa, literally saved my life. I have panic disorder, obsessive-compulsive disorder, generalized anxiety disorder, and borderline personality disorder. I was addicted to Klonopin, and it wasn't even working anymore, making me like a zombie. I started this medicine, and within 2 weeks, I could feel a change. Then by the next month, I went from being a suicidally depressed insomniac with uncontrollable and obsessive thoughts to a normal person. For the first time in my entire life, I feel normal and at peace. This is a Godsend. I seriously don't know what would have happened to me had I not found this medication. It doesn't cure BPD, but my moods are the most controlled they've ever been. There is a light at the end of the dark tunnel."

• Anonymous
• June 17, 2011

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I've been using Anafranil for 6 years. It has helped me a lot. On occasion, I still struggle with obsessive thoughts but have been able to bring it under control both times by myself. I rated this an 8 because of dry mouth and constipation problems. Eat your fiber big time. After several years, the dry mouth problem got better and only returns when I'm under stress. I sleep well on this drug and did not sleep as well on the SSRIs."

• Wolfman
• November 7, 2017

Anafranil (clomipramine) for Obsessive Compulsive Disorder "I battled with OCD since being a child, but I was only diagnosed after being hospitalized in my forties. I have been taking clomipramine at 250 mg a day, along with antipsychotics, for the last 5 years. The intrusive thoughts that used to be so crippling have greatly reduced to a level I can handle. Clomipramine saved my life, literally, as I was hospitalized twice for attempted suicide. The only downside is the side effects. For me, as a man, the impotence and loss of libido are difficult to live with, but it's a price worth paying."