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Cholecalciferol and Heart Palpitations: What Users Say

Brand names: Vitamin D3, D3, Decara, Enfamil D-Vi-Sol, Maximum D3, Replesta, D2000, Celebrate Vitamin D3 Quick-Melt, D3-50, D 1000 IU, Delta D3, D3-5, Ddrops, D-Vita Drops, Replesta Children's, Replesta NX, Thera-D 2000, Thera-D 4000, Carlson D, Bio-D-Mulsion, Bio-D-Mulsion Forte, BProtected Pedia D-Vite, Thera-D Rapid Repletion, D400, UpSpringbaby D, Wellesse Vitamin D3 …show all brand names

Heart palpitations: mentioned by 7 users (14.0%)

Based on user experiences from 50 Cholecalciferol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 18.0%
anxiety 16.0%
heart palpitations 14.0%
increased heart rate 12.0%
nausea 10.0%
tiredness 10.0%
cramps 8.0%
pain 8.0%
constipation 6.0%
depression 6.0%

Reviews for Cholecalciferol

Commonly mentioned side effects
  • Lee...
  • September 7, 2019

Cholecalciferol for Vitamin D Deficiency "So my doc prescribed me 10000 IU for 6 weeks, since I was vitamin D deficient. After 2 weeks of taking these, I noticed terrible heart palpitations and a fast heartbeat. I went to the ER with a heart rate of 172, the scariest day of my life. Vitamin D makes me so drowsy and dizzy. I'm definitely not taking this anymore. It helped me with my levels, now it is 36, but it's making me feel miserable."

3 / 10
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128 Report
  • pja...
  • Taken for less than 1 month
  • August 3, 2020

Cholecalciferol for Vitamin D Insufficiency "1st day fine on Vitamin D3, 2nd day horrible, day 3 no better. Side effects: shakiness, skipped heartbeats, and tired. I've tried this several times in the past few months, all with the same side effects. I'm only taking 1000 IU's. No more taking this as of today."

1 / 10
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111 Report
  • Ano...
  • May 3, 2019

For Vitamin D Deficiency "I was feeling fine until I was diagnosed with vitamin D deficiency (4.6). I took 8000 IU of vitamin D3 once a week for a month. The first time I took it after 3 hours I felt sick all of a sudden, with terrible palpitations, extreme dizziness, nausea, and confusion. I thought I was dying! My doctor said it was impossible vitamin D caused this, so he told me to keep taking the drug. The second week I ended up in the ER, but everything was negative, and they told me it couldn't be vitamin D. I took it 4 times, once a week, until I asked my pharmacist about my symptoms, and he told me to stop immediately. During that month I had constipation, loss of appetite, extreme weight loss, dizziness, fatigue, muscle pain, anxiety, depression, high blood pressure, and scary palpitation episodes (10 times), all symptoms I never had before. Now it's been a month since I've stopped taking vitamin D, and my health is slowly improving. Now my vitamin D level is 16, so I guess the drug worked, but I would never take it again with all those side effects."

2 / 10
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53 Report
  • Eri...
  • Taken for less than 1 month
  • August 22, 2021

For Vitamin D Deficiency "I was advised to take 2,000 IUs of cholecalciferol daily after being diagnosed with a vitamin D deficiency. About 6 hours after my first pill, I noticed my heart was racing, and I started having palpitations. Then the anxiety set in. At this point, I didn’t make the connection with the cholecalciferol, but after continuing to take it over the following days, the anxiety turned to absolute sweaty panic and dread, as well as insomnia. By day 4, I was horribly depressed, had no appetite, and was nauseous. I don’t think my doctor believed me when I told her the cholecalciferol was causing this, but I know that’s what it was. I later learned that cholecalciferol creates serotonin in your brain by increasing the enzyme tryptophan hydroxylase 2. If you get too much serotonin, you develop serotonin syndrome - and my experience aligned exactly with the symptoms of serotonin syndrome. Hopefully, this is helpful to others. For now, I’ll just keep my vitamin D deficiency."

1 / 10
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25 Report
  • Jhi...
  • Taken for less than 1 month
  • January 10, 2021

Cholecalciferol for Vitamin D Deficiency "Wanted to reduce the chance of catching COVID. Been seeing multiple articles about COVID patients being all or almost all deficient in vitamin D. I am obese, have high blood pressure, and very bad lungs, 60 years old. Started having palpitations the first day but didn't make the connection. Took for the third and last time today. Still experiencing the palpitations."

2 / 10
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16 Report

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  • Meg...
  • Taken for 1 to 6 months
  • February 7, 2022

For Vitamin D Deficiency "So I was prescribed 40,000 units of cholecalciferol a week. I took these for 3 weeks. I thought I was going insane, having panic attacks, weird feeling in my hands and feet, like I couldn't walk, had to lie down, and had no energy. Severe dizziness, as if I was going to pass out, and heart palpitations. I went to A&E twice, but they said no, this couldn't be the vitamins. Funny how I've stopped them for 4 weeks and everything's gone, still feel funny to this day, how long until they are fully out of my system? I feel like there's no end. I would rather have my deficiency back than feel like I'm dying."

1 / 10
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  • Jad...
  • Taken for 1 to 6 months
  • January 19, 2021

For Vitamin D Deficiency "I have been diagnosed with hyperthyroidism. I suffered from insomnia, night sweats, irritability, mood swings, chills, gastro issues (gas, acid reflux), heart palpitations, and fatigue. Labs showed a vitamin D deficiency. Doc started me on D3 4,000 IU daily (CVS brand of D3 50 mcg, 2,000 IU twice per day). I feel much better! I sleep through the night, and I'm not as irritable and moody each day. I feel happier and more energetic with less cravings for sugars and carbohydrates. I still feel heart palpitations, but they've decreased since quitting caffeine and getting serious about reducing stress. Diet changes include eliminating caffeine (including NSAIDs), reducing sugar, and eliminating dairy. I think the hormones in dairy contribute to my hormonal imbalance, and my body was desperately trying to compensate (the biggest indicator was adult acne disappearing and reduced growth of random facial hairs). Taking D3 for the last 2 months, along with dietary changes, has greatly improved symptoms."

10 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.