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Wellbutrin XL for Major Depressive Disorder User Reviews (Page 5)

Reviews for Wellbutrin XL

Commonly mentioned side effects
  • bee...
  • Taken for 1 to 2 years
  • December 11, 2021

"Currently on 150 mg. My vision constantly involuntarily blurs, I’m always sweating, my body (especially my hands) tremors, and sometimes I become extremely hyper-aware of everything around me that it begins to feel unreal. Also, I’ve been getting bouts of times where I feel really suicidal. This medication used to work for me, but now? Does nothing positive, except raise my libido."

3 / 10
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  • MIK...
  • Taken for 1 to 2 years
  • March 9, 2018

"I've been taking 150 mg of bupropion XL for years, and it kept me from hurting myself but still had manic depressiveness. I also dealt with seasonal depressive disorder. It was taking the edge off. I wanted to feel able to do things without thinking of every negative possibility. My Doc raised the dosage to 300 mg, and my feelings also became elevated and I feel alive again. Sad to say it has been two weeks, and I have developed gouty arthritis in my right elbow, and it is not going away. I was trying to not call the Dr. because of the good feelings I am having, but the elbow is too painful, and I feel it starting in my left elbow and fingers. I had gout in my feet, never in my elbow, until my sister mentioned that it sounds like gout, and from the feeling and redness with the pain, it is what I felt years ago when I was drinking. Sober for 8 years."

9 / 10
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  • Che...
  • Taken for 1 to 6 months
  • August 22, 2017

"I've been taking this medication for under 6 months now, and I have gained 10 lbs while taking this drug. I don't feel like I have increased energy than before, like some other people described. I feel more irritable and anxious at times, still can't sleep at night. I get the dry mouth side effects and occasional constipation. I'm taking 300 mg XL once a day. I am getting more depressed with gaining weight on this drug! I was taking Lexapro before and didn't find it helped me feel less depressed and experienced a lot of nightmares or weird dreams while taking Lexapro!"

4 / 10
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Frequently asked questions

  • Mic...
  • Taken for 1 to 6 months
  • January 30, 2019

"I've been on this for a couple of months now. At first, my heart rate was sky-high no matter what, and I shook a lot. So my heart rate is still high, but not as high. And I still shake, but not as much. It did help me quit smoking and lose weight. I am not sure what the side effects would be of Aplenzin, but I might try that. Keep in mind, I'm on the highest dose with a mood stabilizer, Abilify, and Buspar."

7 / 10
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  • Ots...
  • Taken for 1 to 2 years
  • January 9, 2019

"I’ve probably taken placebo pills that have worked better than Wellbutrin. It does absolutely nothing, and it makes me appreciate the prescription drugs I have taken before that I didn’t think were doing their job. I still have really dark thoughts from time to time, and my depression has been ghastly lately. Hands down, the least effective antidepressant I have ever taken."

1 / 10
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  • Jon...
  • Taken for less than 1 month
  • October 22, 2015

"I started 2 days ago. I had a bout of diarrhea, but nothing major. I'm not giving up. I went straight to Wellbutrin XL from Zoloft, no reaction there. Anybody else had any diarrhea, hoping this will disappear."

8 / 10
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  • Wil...
  • Taken for 5 to 10 years
  • November 2, 2017

"I was taking this for about 6 years. From 13-18. I had a few spotty teen years where I would barely take the meds, and I ended up in the hospital many times. I had a very weird and high sex drive, and right when I got off, it went away. I had intense night terrors and would start yelling in my sleep, I would sweat so much it looked like I wet myself. The nightmares got so vivid and intense I was confusing reality with my dreams, I would constantly have to ask people if something had happened or not. I lost weight when I was taking this regularly. I've been off for almost two years, and all that being said, I think I may start it up again. It was one of the only depression meds that kept my emotions but kept the bad ones away for the most part."

8 / 10
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More FAQ

  • Lil...
  • Taken for 1 to 6 months
  • January 18, 2018

"I have no doubt that this has helped many people... but for me, this was absolute poison. I'd gone off Lexamil and switched to Wellbutrin 300 mg for MDD. My moods are absolutely all over the place. I'll randomly get sad for absolutely no reason, and for a logical person, this gets frustrating. Not to mention the strain that most of my relationships have been under because of my now explosive temper. I don't feel like the person that I know I am."

2 / 10
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  • Ted...
  • Taken for less than 1 month
  • September 18, 2017

"I'm on 150 mg Wellbutrin XL, and since I've started taking it, I've noticed my dreams are extremely vivid and disturbing. I'm getting confused easily, major insomnia, which isn't normal for me by any means. Was on Prozac, then Lexapro, switched to Celexa after 3 doses, and now I'm stuck with Wellbutrin. I was told to push through and keep taking it, but all of my experiences with stimulants with an amphetamine base have been unpleasant. I'm probably going to discontinue it, I'd rather be unmedicated than lose days of sleep and have horrible dreams whenever I can sleep. Not a great experience, in my opinion."

5 / 10
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  • Bud...
  • January 6, 2016

"Bad, bad side effects from Wellbutrin XL, major palpitations, dry, dry mouth, crying, couldn't sit still, and panic. After taking for 2 weeks, nausea is debilitating. Worst medication I have ever had, back on Paxil CR."

1 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 30, 2022

"This is my second week fully on it and finally tapered off of fluvoxamine. I think it’s doing okay. I’m taking the 150 mg every day, and the side effects I’ve been having are heart palpitations and an increase in anxiety. I hope they go away soon :) Also, I don’t think weight loss is gonna work for me on this because I’m eating a lot but not as bad as when I was on mirtazapine. I think it’s been helping my mood, so I can’t wait to see if it’s gonna help me during the winter when I typically get hit hard with depression. This medicine doesn’t help with my GAD or panic disorder! Only depression!!! Can’t wait to see how it helps further down the road."

8 / 10
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  • Kel...
  • Taken for 6 months to 1 year
  • January 1, 2017

"Increasing the dose from 150 mg to 300 mg daily stopped suicidal ideation, but did not improve anhedonia. Increased dose associated with the onset of hemidyskinesia, which diminished on a lowered dosage and resolved completely when the drug stopped."

3 / 10
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  • Ble...
  • Taken for 6 months to 1 year
  • June 13, 2016

"Brand name Wellbutrin XL 450, severe gain weight, severe anger, severe stomach pain, severe constipation, severe vivid nightmares, made me from social normal person to an unreal horror human, scared to the world.... More than 90 days I can't even get out of my room.... severe panic attacks!!!"

1 / 10
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  • mia...
  • Taken for less than 1 month
  • August 3, 2015

"Today is my first day taking it, and I am hopeful it will work. My doctor has placed me on Vibrid, but that was a $100 out-of-pocket cost. Though I did find it helpful, my insurance copay for it and my budget will not allow me to continue usage. Got off of it for 3 weeks, now starting this one. I have faith - we shall see."

5 / 10
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  • Wil...
  • Taken for 5 to 10 years
  • July 17, 2019

"This drug saved my life and cured my major depressive disorder. I can now live a normal life again to its fullest."

9 / 10
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  • myt...
  • Taken for 2 to 5 years
  • November 4, 2014

"Helped better than any other antidepressant I have taken (and there have been a few!) Major depressive disorder is a tricky one. Still working on that (20 years now), but I'm functional."

6 / 10
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  • per...
  • Taken for 1 to 6 months
  • June 25, 2020

"Wellbutrin XL medication was amazing! Improved my mood, energy, productivity, and relationships. Only downside is I developed moderate to severe tinnitus, so I had to come off. Really disappointed."

9 / 10
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  • Jun...
  • Taken for 2 to 5 years
  • December 4, 2015

"I found that Wellbutrin XL benefited both my mood (stabilized) and helped me with a learning disability. I am able to track numbers and remember a longer sequence of numbers for short-term memory."

10 / 10
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  • Lov...
  • Taken for 6 months to 1 year
  • November 22, 2022

"It's been a great mood stabilizer, and I feel less anxious. It feels so good to go out and have friends instead of hibernating away."

10 / 10
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  • Joc...
  • Taken for 1 to 6 months
  • April 2, 2021

"Worked after about 5 weeks. Lifted mood and generally made me less irritable and more functional. My wife says it has made me far more pleasant to live with. No side effects."

9 / 10
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  • Spa...
  • Taken for less than 1 month
  • April 8, 2019

"I’m having trouble functioning and would like to stay in bed all day, but am pushing myself to do things."

3 / 10
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  • Nel...
  • Taken for less than 1 month
  • March 14, 2019

"I had so many side effects from Wellbutrin, it was too hard to handle. I had a fever, heard ringing in my ears, and was extremely dizzy. My doctor told me to stop taking it immediately."

1 / 10
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  • Ker...
  • Taken for less than 1 month
  • August 29, 2021

"This is a miracle drug. Sex life no good before this drug, I suffered with erectile dysfunction, and it is so much better now. My depression has gone too."

10 / 10
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  • Bad...
  • September 24, 2021

"Things are never going to be perfect, but with Wellbutrin XL they'll at least be 'better.'"

8 / 10
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  • Sap...
  • March 26, 2019

"Sadly, I have been on 300 XR, and I have been so depressed. I went off of it and felt like myself again."

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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