Wellbutrin XL Interactions
There are 527 drugs known to interact with Wellbutrin XL (bupropion), along with 7 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 217 are major, 305 are moderate, and 5 are minor.
- View all 527 medications that may interact with Wellbutrin XL
- View Wellbutrin XL alcohol/food interactions (1)
- View Wellbutrin XL disease interactions (7)
Most frequently checked interactions
View interaction reports for Wellbutrin XL (bupropion) and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Adderall XR (amphetamine / dextroamphetamine)
- albuterol
- buspirone
- clonazepam
- Cymbalta (duloxetine)
- gabapentin
- hydroxyzine
- ibuprofen
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- levothyroxine
- Lexapro (escitalopram)
- lisinopril
- melatonin
- metformin
- omeprazole
- propranolol
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Wellbutrin XL alcohol/food interactions
There is 1 alcohol/food interaction with Wellbutrin XL (bupropion).
Wellbutrin XL disease interactions
There are 7 disease interactions with Wellbutrin XL (bupropion) which include:
- suicidality
- seizure disorders
- angle closure glaucoma
- liver disease
- mixed/manic episode
- renal dysfunction
- weight loss
Report options
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More about Wellbutrin XL (bupropion)
- Wellbutrin XL consumer information
- Compare alternatives
- Pricing & coupons
- Reviews (492)
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Generic availability
- Support group
- Drug class: miscellaneous antidepressants
- Breastfeeding
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
