Bupropion for Major Depressive Disorder User Reviews (Page 5)

• Jade
• Taken for 1 to 2 years
• January 17, 2024

"This medication saved my life, no exaggeration. I had severe depression for months, could not function or work or leave my house. Worse than I thought anyone could ever feel and I was suicidal all day every day. I thought my life would never get better and I had made the calculated decision to end my life if I reached one full year of feeling the way I was. When I started bupropion, I was able to do things again (I would be stuck in a freeze/catatonic state before). It took going up to 300mg (started at 150mg) to stop feeling so suicidal. It also increased my libido which was a positive side effect. Worst side effect was how it affected my hair (I started losing more head hair than usual), but I would much rather be alive and have thinner hair than be dead. I cannot say enough good things about how this medication changed my life."

• Allie
• Taken for 6 months to 1 year
• May 11, 2023

Wellbutrin (bupropion) "I've been battling depression off and on for 25+ years. I've been prescribed Wellbutrin several times, despite my telling the doctor that it does nothing for me. Each time, I was at a therapeutic level dosage-wise (300+mg) and for long enough (6+ months) to be sure of the effects. I have never felt anything from Wellbutrin -- I may as well be taking a placebo. No side effects, no mood effects either way, just nothing. The most recent time I tried it, it wasn't really doing anything, so my psychiatrist took me off it after my ADHD diagnosis for this reason. Zero side effects, zero effects!"

• Donke...
• March 3, 2019

Wellbutrin (bupropion) "Good! There are big pros and some cons. Pros: big decrease in depression and slight decrease in anxiety, slightly increased sex drive, increased curiosity/motivation, improved verbal fluency and thought process, no weight gain. Cons: more aggressive, worse sleep, far more difficult to meditate/fall asleep, struggle to live in the moment due to amplified thoughts. I’ll stick with it as it does work, although the cons could cause me to discontinue. I’ve been on 300mg XL for 2 months."

• Esjay...
• Taken for 1 to 6 months
• January 15, 2015

Wellbutrin XL (bupropion) "I'm 16 and am limited to medications that are safe for me to take because of an extreme anxiety order I have. When I first started Wellbutrin it was slow to see changes but now I can honestly say it's helped me so much. Something a lot of people don't know is that it may also help you lose weight in certain situations. I began my sophomore year at about 180 lbs and now I'm at 155. (I am 5'7") I feel so much healthier now and also happier. I highly recommend this for teens who are struggling with other medicines."

• Johnnie
• January 9, 2017

Wellbutrin XL (bupropion) "I've been taking 15mg remron at night for sleep and also to help out with the depression when I wake up in the morn! I recently started the wellbutrin xl for about 5 weeks now and I think its a good mix for me. Before the wellbutrin I was always tired and not into anything! Feeling down yet once I started wellbutrin it brought me back to life! I can finally do things and be happy about doing stuff. So far so good! I'll keep ya posted..."

• Revere
• November 15, 2016

Wellbutrin (bupropion) "I have been on Wellbutrin for a year and a half. If you do not respond to SSRIs (like me) I would definitely recommend giving Wellbutrin/Bupropion a go. At the end of the fourth week on 150mg, just before I was about to tell my doctor it was another dud - I very suddenly felt clear and not like a slug human. I would say it's such a strong feeling that you will know if it works and the day it starts. I had a horrible time falling asleep, lost my appetite, but felt super ecstatic! Maybe it's because for the first time in 8 years (I am 26) I felt what it's like to not see doing the most simplest of tasks as a stressful chore. I could have cried! I've lost a bit over ten pounds since being on it. Currently I am on the highest dose which is 600"

• Anonymous
• July 6, 2016

Wellbutrin (bupropion) "Taking Wellbutrin 300XL for a while now. Previously used a SSRI which had little to no effect in that I would contemplate suicide nearly daily and had zero interest in life in general. Now I actually want to do things again, I am enjoying life and I have more energy. I can't say enough how well this drug has worked for me. Only side effect I've experienced is decreased appetite and I've lost a few pounds, which for me is a good thing."

• Goods
• Taken for less than 1 month
• March 13, 2020

Wellbutrin (bupropion) "I started wellbutrin and abilify 4 days ago and already I'm noticing some relief. I have anxiety and depression and the anxiety has gone down a noticeable amount. It was at 8.6/10 now it's at a 5.5/10. And I've had anxiety and depression as well as schizophrenia for years now. Finally found a combination that works. I wouldn't say I'm cured though. Just better than before. I also take Loxapine for my schizophrenia. So whatever that combination of Abilify, Wellbutrin, and Loxapine is doing, it's helping."

• Reppy
• Taken for 2 to 5 years
• March 6, 2015

Wellbutrin (bupropion) "Coming from a very problematic childhood, I've been labeled everything from A to Z by psychiatrists and given a slew of meds. Wellbutrin in my experience has been beyond beneficial. At first for the first week or two I had slight tremors, irregular heartbeat, major insomnia and headaches but dismissed. I still have slight insomnia which is why I take them when I wake up. But reading comprehension, multitasking, thought focus and moods overall have dramatically improved! I'm one of those people that may have to take them for the rest of my life but I'm not complaining =). One thing that does bother me tho is dry mouth from wellbutrin but I take biotene which helps a bit. Enough to make it worth it anyways lol."

• mousa
• Taken for 1 to 2 years
• November 8, 2019

Wellbutrin XL (bupropion) "I am diagnosed bipolar I and MDD and I can say after many many meds this quite literally feels like it has saved my life. I have had energy and life since getting put on wellbutrin and recommend it to anyway struggling."

• Veron...
• Taken for 1 to 6 months
• December 25, 2022

Wellbutrin XL (bupropion) "I had major depressive disorder, which became worse during the winter months due to seasonal affective disorder, and was also diagnosed with borderline personality. Within a week of taking Wellbutrin, I went from having crazy mood swings and anger outbursts everyday to feeling calm and stable. For me, it has no listed side effects except weight loss which was a positive!"

• Bob_FL
• Taken for 10 years or more
• March 4, 2020

Wellbutrin (bupropion) "Finally, after 25 years, I was able to stop taking Wellbutrin. My Dr. put me on Trintellix 20 mg which hits the same receptor as Wellbutrin to increase dopamine. It also hits the other major receptors as well. Then, Valeant raised the price of Wellbutrin brand to $1,700, so I bought the Canadian version of 300 XL for $150 per month. However, now that I'm on Trintellix, I'm thrilled to get off Wellbutrin which is the cause of so many complaints as a generic. Also, with Trintellix, there's no time-release (SR or XL) - so, this eliminates the dispensing of the drug in the body at various rates - as can be felt between generic and brand. This is just my experience as a veteran of anti-depressants. Trintellix is still in brand form only and costs about $295 per month."

• mdog
• Taken for 6 months to 1 year
• December 5, 2022

Wellbutrin (bupropion) "I wanted to share my experience because people may be scared away by negative reviews about this drug. Wellbutrin truly saved me. I was dealing with very severe depression, not getting out of bed for days, not wanting to live 24/7. Wellbutrin has been a Godsend for me. I have been able to go back to school, work again, do CrossFit like I used to, and get closer to the person I was before all the depression. I will admit it does have some side effects, especially when starting, but I stuck it out, and I am SO glad I did."

• Changed...
• Taken for 10 years or more
• April 18, 2022

Wellbutrin (bupropion) "Wellbutrin XL 300 mg once a day changed my life. I have used it for 20+ years. I started using it when it came out to help keep my weight down and to help with amotivation aspects of depression. This medication helped me with motivation, socialization, and pushing myself to achieve more. I would not have become a doctor or gotten married without Wellbutrin. However, after all these years, I realized the fibromyalgia I have been fighting for years is due to Wellbutrin. It has gotten so bad that I would constant neck spasms and not be able to get out of bed without taking several layers of pain medication. I read up that Wellbutrin can cause myalgias. I was also taking Adderall for my ADD, this also worsened the muscle spasms. I currently had to stop Wellbutrin completely. Myalgias went away. I have tried other medications for depression, but nothing has giving me the get up and move attitude like Wellbutrin does."

• Mano
• Taken for less than 1 month
• August 18, 2019

Wellbutrin XL (bupropion) "Since patients come to this site to gauge whether to try a new prescription, I'll describe how Wellbutrin XL 150mg has affected me in one week. I asked my doctor to switch from Celexa since it was just OK, but not as effective as I wanted. The first side effects I have been experiencing are: drowsiness in the mornings (not fatigue, but cold medicine), heart palpitations (when I have tea or coffee in the morning; coffee is 10x worse no matter when I drink it, even decaf). Also, in the afternoons or evenings I get this heavy, weighted feeling all over my body, like it's too hard to lift arms and legs, plus added sleepiness. On the plus side, I have not felt depressed or unmotivated. Above all, my libido has gone from 0 to 100 in a few days (I have never been completely mentally and physically engaged in sex before; something on my mind always got in the way)."

• Britt
• October 5, 2019

Wellbutrin (bupropion) "Have been on Wellbutrin for almost a month now. I was originally prescribed 150 mg once per day, but my psychiatrist recently upped my dosage to 300 mg per day. The only reason I’m rating a 5 is because I haven’t felt any drastic difference yet as it takes time for these medications to work. The things I have noticed is that I don’t feel sad anymore and I don’t cry near as much. Right now I’m feeling complete apathy and indifferent towards everything, and my psychiatrist ensures me that I am on my way to recovery."

• Usele...
• Taken for 6 months to 1 year
• January 23, 2020

Wellbutrin (bupropion) "Does nothing for depression. Dried me out to the point of needing steroid eye drops and regular eye drops every 4 hours. I would also wake up every night with a dry mouth. Don't take if you have insomnia. More of my life wasted trying potions."

• GrNana
• Taken for 6 months to 1 year
• March 16, 2022

Wellbutrin (bupropion) "Wellbutrin or Bupropion is by far the best medicine I've taken for relieving depression. It takes time on this med so don't give up too soon. I have been on 300mg for 6 months and I am seeing results that I never saw with other antidepressants and I have taken most of them at one time or other. Every antidepressant I've taken in the past caused me such apathy I can't function. I now have pleasant or even joyous thoughts occasionally and I am getting interested in life again."

• Steph...
• Taken for 2 to 5 years
• December 5, 2014

Wellbutrin SR (bupropion) "I started this medication at a time when I did not have any health insurance and had to pay around $40/month for it. One of the very first things I noticed when taking this medication was that I started smoking fewer cigarettes, it made the cigarettes taste the way they should, horrible. I never had any other side effects from the medication. When I switched to another medication, it became very apparent that I was not doing as well as I had been while on the Wellbutrin SR, so I switched back after a few months and a couple different meds. This is definitely my favorite; I'd been on several different medications for my MDD and always had terrible side effects. Not with this!"

• Eano
• June 30, 2020

Wellbutrin (bupropion) "Let me start off by saying my body is super weird and sensitive to medication. I do not need a high dose of anything and I typically get side effects with anything I take. I took 30mg of Wellbutrin for about a month and within that month was miserable. I had very bad gut pain and digestive issues, so my doctor dropped me down to 15mg. I was on that for another 2 weeks before quitting. So in 45 days of being on Wellbutrin, I got terrible adult acne on my face and chest, severe digestion issues and gut pain, and gained 10-12 pounds in water weight (I felt bloated 24/7 - like I was on my period), headaches and had severe angry outburst (which is not to my character). It is a bummer I had such horrible side effects because it really did help greatly with my depression, it also gave me a huge sex drive (which my husband loved!). But there were just too many had side effects to justify staying on it."

• Anonymous
• Taken for 2 to 5 years
• January 7, 2016

Wellbutrin XL (bupropion) "I have tried many different kinds of antidepressants but I must say that Wellbutrin XL300mg has been the best. I have been on it for 3 years. I am so much happier and just feel better in general. The only side effect I have had while taking it is dry mouth. I was always a calm, attentive student even before I had the medicine. But since I have been taking it so long, if I happen to miss one or more days of taking it, I act as if I have ADHD. I am unable to focus and talk like a Chatty Cathy. If you have ever seen a little seven year old with really bad ADHD.That's me. I will skip in place, bounce up and down, and what not. I have NEVER had ADHD or ADD (I am super calm), but if I don't take it I act like it. That's my one and only problem."

• Butte...
• January 24, 2017

Wellbutrin XL (bupropion) "I've only been on this medication since the 18th of this month, but one thing that I have noticed with this medication is that it is helping me to not have a constant appetite. I was not only needing help with depression, but I was also needing help with weight loss and at this point I don't know how the weight-loss will/will not work with med, but I do know that I do not have an appetite like before taking this. And for that I am very grateful. I also understand that it could take 3 to 4 weeks before I notice the effects for the depression. I am hopeful!"

• Koala...
• Taken for 1 to 6 months
• November 9, 2014

Wellbutrin SR (bupropion) "I was skeptical about bupropion. I started this at 150mg. I am BiPolar- and must say that it has been a God send. I read up on it and how it can give you energy plus can also help with concentration, I scoffed in a way. No longer do I scoff. I am so grateful that I take this, it does not effect any SSRI's as it's differently made up. I am on Zoloft and bupropion, these do not cause me a problem. It is possible to take these with BIPolar, yes, there is research regarding anti depressants and BiPolar, but for me it has given me back my life- I do have energy to leave the house, I can concentrate, my memory is better, but I now have a life- a social life. I go out. So please don't be scared off, by antidepressants and BiPolar- ask the question."

• coming...
• December 31, 2015

Wellbutrin (bupropion) "I was on 150 MG efexor for nearly a year and continued suffering with depression and anxiety. It affected my libido to the point that I couldn't stand being touched by my husband. I've been on wellbutrin for nearly three weeks and it's been a miracle for me. My energy level is up, I can focus again, and my libido has increased. The only negative I have had is it doesn't help my anxiety."

• Pinkl...
• November 19, 2014

Wellbutrin (bupropion) "I have Post Traumatic Stress Disorder and have also suffered the loss of my family. I had 5 major surgeries in one year and have attempted suicide several times. I've been on a variety of meds and have watched my weight balloon from 140 to 240lbs because of these medicines. Am I better because of Wellbutrin maybe at first and it is easier to move my life along. Side effects, itching that drives me nuts, no sex drive, I've only been able to drop 40lbs, can't sleep, agitated really easy over stupid stuff, cry at the smallest thing. Yes, I still have days I don't want to get out of bed but after a while I finally do. No suicide thoughts right now which is good."