Skip to main content

Bupropion / naltrexone User Reviews & Ratings (Page 5)

Brand names: Contrave

Bupropion / naltrexone has an average rating of 6.6 out of 10 from a total of 2,069 reviews on Drugs.com. 55% of reviewers reported a positive experience, while 25% reported a negative experience.

Reviews for Bupropion / naltrexone

Commonly mentioned side effects
  • Les...
  • Taken for 1 to 6 months
  • January 16, 2019

For Weight Loss (Obesity/Overweight) "It doesn't start working right away, so give it at least a month! Bad reviews probably come from people who haven't taken it long enough. After taking Contrave for about six weeks, I now just naturally seem to want healthy food, and junkier food is actually repulsive. I'm also satisfied with far less. I haven't experienced any side effects except an occasional momentary dizzy feeling. Good luck, everyone!"

10 / 10
Was this helpful?YesNo
85 Report
  • Dol...
  • Taken for less than 1 month
  • June 23, 2019

For Weight Loss (Obesity/Overweight) "I started Contrave 5 days ago and have lost 5 lbs already! I’m excited to see how much weight I will lose on this! Side effects: I felt a little jittery; however, I think this could be from not eating very much. I notice once I eat something, this goes away. Feel slightly ‘out of it’, for instance I can ask someone something and they tell me, and I won’t remember a second later what they said. Very difficult getting to sleep and staying asleep the first couple of days, but it has been getting better by the day. I am nervous about increasing the dose and not being able to sleep again. Increased energy, mild constipation, mild dry mouth. Zero cravings for anything. It makes it really easy to eat clean, avoid carbs, and sugar. I’m not hungry at all. For the first time in my life, I don’t feel like I’m obsessing over food like an addict. I don’t even think about it. When I do eat, I get full really fast."

9 / 10
Was this helpful?YesNo
79 Report
  • nic...
  • Taken for 6 months to 1 year
  • May 20, 2019

For Weight Loss (Obesity/Overweight) "I lost weight of 55 pounds (25 kg) between May and October last year with the help of Contrave. I used 4 pills per day and had no notable side effects. After that, I moved down to 2 pills per day until the end of December. But when moving to 2 pills, I immediately noticed the appetite-suppressing effect wasn't as good and I gained 10 pounds back by the end of the year. From January, I stopped the drug completely, and what happened to me when I stopped Contrave completely - I have now gained back 45 pounds of the 55 I lost. I started Contrave (4 pills per day) again in March, but this time I don't feel the effect as good as earlier, which is disappointing. As advice to all of you, don't stop the full dose too early and make sure you know how to eat without gaining weight. And stick hard to the new eating habits after stopping Contrave, you don't want to start the same weight loss process over again..."

8 / 10
Was this helpful?YesNo
78 Report

Frequently asked questions

  • Hap...
  • December 8, 2018

For Weight Loss (Obesity/Overweight) "Started Contrave in May of 2018 at 342 lbs. I didn't take my weight loss seriously, I actually gained 7 lbs. My doctor threatened to cut my medication if I didn't lose at least 10 lbs by my next 3-month checkup. I started walking 4-7 miles a day. I also started drinking a lot of water. In 3 months, I lost 70 lbs. The circulation and color in my legs returned, I have more energy, fit in a plane seat, and can tie my shoes. I went from a size 48 to a 36 waistline. After ramping up to 2 pills a day in the morning (I never took the 2 pills in the evening as I misread the instructions), when I discovered my mistake, I decided to just keep taking the 2 pills a day because it worked. No weight loss program is going to work if you are not all in. I expected the drug to do all of the work when I first began - mistake. I would recommend it, but you do have to work with it. Good luck on your health improvement journey. Over 50 and feeling great."

9 / 10
Was this helpful?YesNo
83 Report
  • STA...
  • Taken for 1 to 6 months
  • July 31, 2018

For Weight Loss (Obesity/Overweight) "Like most of you, I was wary of starting Contrave due to bad reviews. Well, I started Contrave on Feb. 12th, 2018, at 250 lbs. Now I've come back to shed a little light in the dark! July 30th, 2018, I'm 155 lbs and so happy. Contrave does do its job, but you have to let it. Don't give up because of headaches and etc. Contrave does come with a lot of side effects, but you have to let your body get used to it. Adapt to the change. It took me a while, but I did do it. Any spare chance I got, I was working out. Even for a few minutes in my bedroom every night. Eating right also helped, fruits, vegetables. I did have the bad constipation and headaches, but I found ways to look past it, and what helped was vitamins, fibers, natural medicines! Anything to keep me pushing forth!! I hope this helped reassure a few people that you can do it - because I did."

7 / 10
Was this helpful?YesNo
85 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • JLa...
  • Taken for 1 to 6 months
  • February 14, 2021

For Weight Loss (Obesity/Overweight) "Six weeks into my Contrave journey and I am loving it. I have lost 10.2 kg (22.4 lbs) so far and I feel amazing. I had mild side effects for the first four weeks - some dizziness and headaches (usually worse the day after increasing the dose) and constipation. All side effects ceased after week four, but I do continue to take a stool softener every few days as a precaution. Food cravings disappeared within a few hours of the first tablet, and I am able to stick to a 1000-calorie diet, eating three meals and a small snack each day. I have been exercising every day (cardio four times a week, yoga three to four times a week, and walking 8000 to 10000 steps a day). I haven't drunk coffee since week two and barely drink alcohol as I don't feel like it and was worried about seizures. I think Contrave is amazing, I feel for the first time ever that losing 28 kg will actually be achievable, and what's more, I am already 10 kg down... only 18 kg more to go to put me from obese to a healthy weight range for my height."

10 / 10
Was this helpful?YesNo
60 Report
  • Pre...
  • March 19, 2015

For Weight Loss (Obesity/Overweight) "I started Contrave on March 1st, and as of March 19th, I'm down 15 pounds! I'm very pleased with that amount of weight lost. I have not had any side effects so far, so I will continue on. I will check back later and give you an update on what the full one-month total weight loss was."

10 / 10
Was this helpful?YesNo
120 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 9, 2024

"I went from 110 to 160 in 1.5 years or less due to my binge eating disorder. I decided to talk to my family doctor after doing research and was able to get Contrave for free from my insurance, along with the 10% extra they provide, which is awesome. I struggled to take them for the first couple of weeks because they were so big, but I got used to it after a while. They made me very nauseous, and I would have to sit at the end of my bed and breathe for 10 minutes before getting up in the morning. No, you shouldn't drink while taking Contrave. I did once and threw up the next day when I was getting ready for work in the morning. Not a good idea. Contrave completely suppressed my appetite, but I was eating healthy and having 3 meals a day. After losing 40 pounds in 4 months and being back at my pre-binge weight, I went off them and developed healthy eating habits, including homemade meals. I could not have done it without Contrave. It was the best decision I've ever made, to be honest."

10 / 10
Was this helpful?YesNo
24 Report
  • Mic...
  • January 5, 2021

For Weight Loss (Obesity/Overweight) "I have been struggling with weight loss since my hysterectomy. My starting weight was 168, and I am down to 160. I just started week 3, taking 2 pills in the AM and 1 pill in the PM. I really have not changed my diet. I do not crave sugar or carbs. I can just walk away from the donut. I can't report any side effects. I have not felt nausea or any of the listed side effects. I plan on adding more exercise. For me, this pill works."

10 / 10
Was this helpful?YesNo
60 Report
  • Hea...
  • Taken for 1 to 6 months
  • August 7, 2017

For Weight Loss (Obesity/Overweight) "UPDATE: Starting weight 221.6 lbs on April 8th, 5 ft 3 in tall, 47-year-old female, this morning I am 188 lbs. That's 33.6 lbs down basically without exercising. Down from a size 18 shorts to a 14. I have a few clothes that once were too tight and my gut hung over that fit me now. And shorts I bought 4 years ago that I can pull off without unbuttoning. I have jeans from 2004 that I kept that were sentimental and I can almost button without a muffin top. This is why I push on... this is something I never thought I would feel, I look in the mirror and sorta see the old me coming back... it's working for me and my husband can tell you my self-confidence is better than it's been in a LONG time!"

9 / 10
Was this helpful?YesNo
93 Report
  • Cha...
  • February 5, 2017

For Weight Loss (Obesity/Overweight) "I'm a 28-year-old female. Started out at 233 lbs. Doctor put me on Phentermine, and it was the WORST - ended up in the hospital with severe dehydration and heart palpitations. It also made me so tired I couldn't even function! Thankfully, she took me off last week and started me on Contrave for my addictive personality (food and cigarettes). Well, this is day 5, and I haven't had a craving for a ciggy yet AND I'm down 8 lbs. The key is YOU HAVE TO EAT. You have to eat 5 small meals a day and drink, drink, drink that water! Incorporate exercise too. I don't think most people are doing any of the above, that's why they have no results! I haven't had any side effects (yet, knock on wood). But I really think this medicine is it."

10 / 10
Was this helpful?YesNo
98 Report
  • Anonymous
  • Taken for 1 to 6 months
  • January 8, 2019

For Weight Loss (Obesity/Overweight) "Ok, I have now been taking Contrave for 12 weeks and the results are amazing. I am down 45 pounds. At the lowest weight in over 25 years and feeling great. I eat what I want, just half of what I used to but also making some smarter food choices, never do I consider myself on a diet. I have lost some weight in each week I have been on Contrave. This is the real deal, I would recommend it to anyone."

10 / 10
Was this helpful?YesNo
78 Report
  • Kel...
  • Taken for 6 months to 1 year
  • July 9, 2017

For Weight Loss (Obesity/Overweight) "I have been on Contrave for 9 months and have lost 80.1 pounds. I still have to do the work (eat right and exercise). For me, it has been a tool to help me make better decisions. I still have a ways to go, but am confident I can continue to be successful."

10 / 10
Was this helpful?YesNo
86 Report
  • Ste...
  • Taken for 1 to 6 months
  • March 3, 2020

For Weight Loss (Obesity/Overweight) "I was one of the few that didn't see a result. I had the nausea, as most everyone else did. I followed the dosage directions perfectly. I read that if you don't see any change in appetite by the 4th week, you probably won't. That much is true. I gave it 3 months."

1 / 10
Was this helpful?YesNo
68 Report
  • No...
  • February 27, 2019

For Weight Loss (Obesity/Overweight) "I am 52 and weighed in at 312 lb just 5 weeks ago at my Dr.'s office. My high blood pressure was in check, but I kept gaining a few lbs each year and felt sluggish. What was this 'diet pill' going to do... Nothing to lose, right? I’ve taken weight loss pills before but none since I had bad reactions in my 30s. I was eager to see how science had progressed in 20+ years. So I started taking Contrave and tried to start cutting back on lunch portions and dinner. I usually eat a 6” Subway with chips and a bottle of water. Then eat a Lean Cuisine (or 2) for dinner. I must admit, I’ve been eating a low-calorie treat after dinner and drink a cup of coffee every night. I must be one of the exceptions to the postings here, but I have had little to no side effects at all. After 5 complete weeks, I’ve gone from 312 to 292. That's 20 lbs in 5 weeks!!!! I got the jumpstart I needed. So, I’m not excited about it, but I am going to start exercising now... Ugh."

10 / 10
Was this helpful?YesNo
76 Report
  • Anonymous
  • Taken for less than 1 month
  • March 13, 2017

For Weight Loss (Obesity/Overweight) "UPDATE..SW 259 as of 2/27 CW 255. Today is 3/13 CW 249, yes, this is correct. I can't believe the scale. I am ashamed to admit I still haven't incorporated exercise. For those who are reading this and can't decide based on these comments, you need to try it yourself. I was so afraid to try it after reading what people were experiencing with the symptoms. I have no symptoms, and I am taking 2 pills in the morning and 1 at night. My insurance covered it, so I only paid $30.00 with a coupon for 120 pills. My doctor called and scheduled a 6-week follow-up appointment to see if it's working. We're aiming for 5% OF MY BODY WEIGHT in 6 weeks. At this rate, I will have surpassed that goal. If this pill did not work for me, my next option was surgery."

9 / 10
Was this helpful?YesNo
89 Report
  • Edz...
  • Taken for less than 1 month
  • September 11, 2020

For Weight Loss (Obesity/Overweight) "I started using Contrave 2 weeks ago. The first day I was good, the second day I felt a little sick. On the third day, I was Googling the 'best nausea pills.' I was ready to give up. I had headaches, felt very weak, and didn't eat at all for the next 2 days. I also was sleeping very lightly (I'm a heavy sleeper) and woke up multiple times during the night. That was my first week. In the second week, I was afraid to take 2 pills, but I must say in the second week my body got used to the pills. I'm now coming into my third week. I feel fine. I lost 2 kgs already, but it was mostly from being sick and not eating. I do feel my appetite has lessened a lot. If you can get through the first week, give it a chance. Drink lots of water, exercise, and eat a lot of small portioned healthy meals and snacks, our body still needs its fuel :)"

8 / 10
Was this helpful?YesNo
59 Report
  • Anonymous
  • Taken for 2 to 5 years
  • July 8, 2022

For Weight Loss (Obesity/Overweight) "Five years ago, I was 200 lbs, 5'4'', size 12/14. I started on Contrave, and 1 year later, I was 50 lbs less & a size 6. Today, I fluctuate between 140-145 lbs & remain size 6. I did go off it for a few months at a time, & when starting to gain, would start back. I had accumulated many bottles, so I do take 1/2 my dose daily. Hopefully, when I run out, I can maintain on my own. I plan to wean down with my last two bottles, as I will not be eligible for refills. Worst side effects: constipation, feeling forgetful/spacy & heartburn (the early days only)."

10 / 10
Was this helpful?YesNo
39 Report
  • Tha...
  • Taken for 1 to 6 months
  • February 24, 2017

For Weight Loss (Obesity/Overweight) "I started taking Contrave December 8, 2017. I have a very stressful job and sit pretty much all day. My weight is a problem and I need to lose around 120 lbs total. Today, 2 and 1/2 months after starting Contrave, I am down 28 pounds!!! I no longer crave chocolate and I don't eat unless I'm hungry. I haven't started a set exercise plan yet, have just been modifying my eating/sugar intake. First month or so, I did not experience any negative side effects. Have recently had some issues with constipation but I added back my morning cup of coffee and that has helped :) Also have experienced a little bit of dry mouth but that helps me drink more water, which is a plus. Overall I am very happy with these results!"

10 / 10
Was this helpful?YesNo
86 Report
  • Mam...
  • June 24, 2017

For Weight Loss (Obesity/Overweight) "I'm down 17 pounds in 23 days. I have NEVER had this kind of positive result from anything I've tried. I have PCOS so my hormones made losing weight almost impossible. I have found that I've had to play with the dosage a bit... when I got to week 3 where I'm supposed to take 2 pills in the morning and 1 at night, the nausea was intolerable and I wasn't able to sleep at night. I found that taking one in the morning and 1 around 2-3 in the afternoon seems to be my 'sweet spot'. The only side effects are occasional nausea, constipation (easily managed with senna), and extreme dry mouth, which helps with my water intake! I cannot wait to see what results are down the road for me!"

10 / 10
Was this helpful?YesNo
84 Report
  • Hey...
  • May 29, 2020

For Weight Loss (Obesity/Overweight) "Day 1: 9am I took my first tablet with breakfast (poached egg on toast). Felt great and went for a 6 k walk. At 1pm I was feeling very nauseous and also very spaced out. Spent 2 hours in bed. At 3:30pm I got up and had some soup and felt fine. Day 2: I was very nervous about taking the tablet again, so I contacted the doctor and she prescribed anti-nausea meds. I took my tablet with beans and toast and drank plenty of water. It is now 2:30pm and I feel fine, I didn’t need to take the anti-nausea medication."

7 / 10
Was this helpful?YesNo
61 Report
  • Jaa...
  • Taken for less than 1 month
  • March 4, 2017

For Weight Loss (Obesity/Overweight) "I have a pharmacy background and I have a great doctor. I have had no working thyroid in over 2 decades. We put our heads together after I researched low-dose naltrexone for weight loss and I stumbled into this drug. Myself knowing how Rx coverage usually works or 'doesn't'. We discussed mirroring this drug with the two generic ingredients. One 200 mg bupropion and half of a 50 mg naltrexone in the AM and the same in the PM. Added the bupropion first 2 weeks ago and added the naltrexone today. For those of you that love this drug but simply can't afford it, this option may be worth mentioning to your doctor since 99% of insurance has no problem paying for these cheap drugs. I will post my results weekly in case anyone finds this alternative interesting."

9 / 10
Was this helpful?YesNo
89 Report
  • Ano...
  • Taken for 6 months to 1 year
  • July 23, 2023

For Weight Loss (Obesity/Overweight) "Highly recommend. I’m 5’5, mid-30s, female. Started this drug at 282 lbs. Seven months later, I am down to 239, without adding exercise, but I am going to as a next step. Side effects are manageable. They include headaches and I find myself a little short-tempered, although I’m not sure if that is from this or not. I did try Ozempic and had horrific stomach pains and gastro; my body just can’t tolerate it. This has been a great alternative for me. I still eat everything I want, but I don’t crave unhealthy portions anymore. It was not uncommon for me to eat huge amounts of food, especially when stressed or upset. Now, food has no appeal unless I am actually hungry, and I stop eating when full without issue. Such a simple thing, but not for me."

10 / 10
Was this helpful?YesNo
27 Report
  • can...
  • Taken for 1 to 6 months
  • January 3, 2025

"I took Contrave for 2 months, one pill per day. For me, the medication was excellent. It helped with cravings, and I had feelings of fullness. I would snack and eat all day prior to taking it, particularly at night, and this pill really helped. Without cravings and obsessing over food, I exercised 3-4 times a week and ate what I wanted (healthy mostly). It's recommended not to take the pill with high-fat food. I still ate fatty food sometimes and still lost the weight as I ate less than what I used to eat. I lost 15 lbs in 2 months, from 156 lbs to 136 lbs with no side effects. I stopped taking it for 3 months, and cravings returned. I'm now taking it daily, and it's helping again. Medical covered it, but without coverage it's expensive."

9 / 10
Was this helpful?YesNo
7 Report
  • Cit...
  • Taken for 1 to 6 months
  • June 18, 2019

For Weight Loss (Obesity/Overweight) "I am exactly 2 months in. I have lost 10 pounds. No, that's not a huge amount like some of the other people you see on here, but I guarantee you that I would have lost ZERO pounds if I hadn't taken this drug. At first, I had some daytime drowsiness and some vivid dreams, but that has gone away. It also causes some constipation, but I have IBS-D, so this actually balanced things out for me, lol. I think this works depending on what your food issue is. I have a bit of an addictive personality, and this has really helped me. I don't obsess over food anymore. I feel like a 'normal' person when it's mealtime. I only eat when I'm actually HUNGRY and not when I'm bored, sad, happy, celebrating, or whatever. I don't mindlessly eat when I'm watching my shows. I don't even think about food at all unless I'm physically hungry. It has really helped me, and I'm excited that I'm finally going down in weight instead of up."

8 / 10
Was this helpful?YesNo
64 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.