Bupropion / naltrexone User Reviews & Ratings (Page 4)
Brand names: Contrave
Bupropion / naltrexone has an average rating of 6.6 out of 10 from a total of 2,050 reviews on Drugs.com. 56% of reviewers reported a positive experience, while 25% reported a negative experience.
Reviews for Bupropion / naltrexone
- Tor...
- Taken for less than 1 month
- August 10, 2024
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "Love it! Totally took away obsessive food thoughts, I no longer feel excited about all foods I used to pig out on and can easily pass by them in the store without a compulsion to buy or eat them. The pleasure centers are calm and do not respond to food as if it were a hard drug - food addiction is under control now. I also feel full much sooner and by smaller volumes of food, albeit it is not a formal indication. I am a fan, what can I say? The only side effects that I am experiencing are constipation and, if I happen to take it after 5 PM, I end up not being able to fall asleep until midnight, which is a bummer for me because I am an early riser. Watching that I take it before 5 PM solves the latter issue. I am still figuring out how to manage constipation without drugs. Despite these, I absolutely love how Contrave manages my compulsive eating and oversized portions."
- Val...
- Taken for 1 to 6 months
- June 26, 2017
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I've been on Contrave for 6 weeks and am 20 pounds down (Starting weight 308lb now 288lb)!! At first the side effects were pretty bad. Highly recommend to increase doses when starting this medication as the website suggests. I experienced a bit of dizziness, sweating, and dry mouth are the main side effects for me. I made myself continue on the medication and the side effects lessened as my body got used to it. Now the side effects are minimal and worth dealing with for the results I am seeing. Hang in there if you're trying it out! I rarely actually feel hungry. I eat small meals just to keep my body going. The best thing and most important for me is that I DO NOT crave anything like I did before, so I can control my eating choices. What a Godsend!!"
Frequently asked questions
- tmt...
- Taken for 6 months to 1 year
- October 3, 2016
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I have lost 88 pounds in 10 months. I had some drowsiness and increased sweating at first but improved within a few weeks. A small price to pay for the overall improvement in my quality of life. I believe the effectiveness depends upon the underlying reason for obesity. Naltrexone lowers cravings and improves addictive behavior. My problem was the compulsion to binge eat high-calorie foods. I don't know how effective it would be on obesity for other underlying reasons, which may explain why it works for some and not for others. My life has improved and I can do things I have been unable to do in years. Very pleased!"
- Mom...
- Taken for 1 to 6 months
- August 25, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "So the entire first month I took this, I felt totally gypped. It didn’t seem to make a darn bit of difference! I was pretty upset, considering how much it cost. But something told me to at least try one more month, and lo and behold, after about the five-week mark, I started noticing a marked difference in my cravings and hunger pangs. It’s not like some other prescription weight loss aids - it’s not going to suddenly make you feel like you’re full from sun up to sundown without eating anything. All it does is quiet down your cravings, so that you can make smarter choices when you ARE hungry. You have to be willing to work with it."
Are you taking this medicine?
Your review helps others make informed decisions.- Mrs...
- Taken for 1 to 6 months
- November 13, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I am very happy with this Contrave pill; I take it right before bed and at lunchtime. I have never experienced nausea or headaches, but I have experienced constipation (which I remedied with extra water and vegetables) and some restless nights around week three. I didn't have much to lose, so it's not falling off, but it allows me to not crave food, binge eat, and I really could care less about a drink at night or on the weekends. My water consumption is at 100 oz, which is a huge improvement!"
- Ang...
- Taken for 1 to 2 years
- December 28, 2016
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I was on this medication for 1 year at 201 lbs, 5'3'', age 23. I was down to 158 lbs without going to the gym ever. The first three months were awful. Dizziness, blurry vision, but the first month had constant headaches. After that, I ate very little and got full fast. I even quit drinking. It also helped with my depression and energy. I've been off of it for 6 months and have gained 10 lbs. Food cravings and depression are back. Have to wait 6 months for an appointment to get a refill. I am dependent on it."
- A I...
- January 4, 2017
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I have PCOS and hypothyroidism, so losing weight is difficult for me. My doctor prescribed Contrave 3 months ago. At first, the side effects were very difficult. I was nauseated, and I felt really dizzy. At first, I didn't lose that much weight with it either; however, after about 2 weeks, I started losing weight and am currently down 25 pounds. I was very lucky as my prescription drug insurance changed at the beginning of this year, and the new plan covers it with only a copay of $80 for a 3-month supply. I am thrilled with that. I have had constipation, but nothing that I cannot handle. I would suggest this drug if you have metabolic diseases. For me, the cravings disappeared, but I feel my body is burning more calories in the process."
- hec...
- May 22, 2021
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "My starting weight was 267 (though I've weighed as much as 340 in my life), and my current weight is 252, with a target weight of 185-190. I am taking 2 tablets twice a day with food and am on a low-calorie diet (1100-1200) and am working out (cardio and weights) 3 times a week. I also walk my dogs while logging food. It may help some people to know that I'm on Adderall as well. My doctors recommended Contrave because they can be taken in conjunction with one another. I'm a 32-year-old white male who is 6 ft tall. My diet habits have never been good but haven't been bad either. My problem has always been binge eating/drinking in the evenings. Contrave was originally designed as an anti-depressant/alcohol/opioid addiction medication before they realized that blocking the part of the brain that controls addiction and impulse leads to weight loss. I haven't had or wanted a drink in ten days."
- Arc...
- February 4, 2015
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I weighed 163 lbs when I started this medicine. I dropped 10 lbs during the first month. I also started medication for thyroid issues, so that might be part of it. However, my cravings are completely gone! The medicine also helps a bit with my depression, and I feel more determined to work out. I'm pretty happy with it."
- Fut...
- February 1, 2015
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I don't know if I would have made it through the side effects if I didn't have a closer friend starting Contrave at the same time. Headache, dizziness, nausea, sleepy but they have all almost gone away. If you can make it through the first 1-2 weeks it gets better. The 20lbs I've lost makes it worthwhile."
- EDi...
- January 1, 2017
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I'm on the 4th week of taking Contrave, with 2 in the morning and 2 in the evening. So far the only side effects I've experienced were in the second week. I started getting dry mouth and motion sickness when in the car. The motion sickness stopped after a week. I still get dry mouth, but I can deal with that. The first 3 weeks, it didn't seem to suppress my appetite, but I successfully stopped a lifelong habit of drinking soda with no cravings. Since I started taking the full dose, it's now controlling my appetite. The past 4 days, I have no desire to snack, and I feel very full after eating half of a meal, and I continue to have that full feeling long after eating. So far, 5 lbs down with no exercise. I'm optimistic, time will tell."
- Cin...
- January 20, 2017
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I have just completed my first month on Contrave. I have lost 9 pounds. I didn't experience any significant side effects. I was nervous at first because I didn't want something influencing my mind, but the only thing it influenced was my appetite. I am less hungry all the time. I often have to force myself to eat. I am working on making better eating choices and exercising. So far, so good! I just purchased my second-month supply and am eager to keep losing the weight. I will post again after this supply is finished."
- Res...
- Taken for 6 months to 1 year
- May 31, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "Been on Contrave since Nov of 2018. Beginning weight 323 lb and I’m 5’8. I’m down 40 lbs now. Had a couple ups and downs because I am not as committed with exercise as I should be. Definitely curbs cravings and can only eat small portions. The one side effect I struggle with is gagging. I can be enjoying my meal and all of a sudden my body tells my brain that I’m done. It’s almost a feeling of disgust with my food that makes me gag and many times have to spit food out in a napkin. Even if it’s my most favorite thing to eat in the world... it’s so weird!!! Mild diarrhea for me as well, but I also have a very sensitive digestive system. Overall I think this medication has done wonders to improve my life. Weight, confidence, depression... many positive perks and recommend for anyone with weight struggles to give it a go. Insurance didn’t cover the cost but you can get a coupon from the Contrave website to help with saving some money."
- She...
- Taken for less than 1 month
- February 5, 2015
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I've finished week 2 on Contrave. I'm down 4 pounds. My doctor is pleased. He doesn't want me losing any faster than that. For me, no side effects. My doctor also said it can take 4 weeks for the full effect, which makes sense because it takes that long to get to the full dose. Stick with it."
- SKI...
- Taken for less than 1 month
- September 25, 2017
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "OK - today is day 1. (9/25/17) I started at 2 pm (because it arrived then) & it's 4:30 pm. So far, I became very sleepy, which is ok, but I'm at work. No Nausea yet - so YAY! I'm about 200 lb - 5'2, so I'm hoping to lose a lot, at least 50 lb - 60 lbs. My knees hurt, & I avoid looking at myself naked anymore. I just wanna fit in my pants from 5 years ago. I think I've gained a lot of weight just from stress & getting older - I'm 47 years old. I used to lose weight so easily, but not anymore. I'm hungry all the time, and I think I can eat about 5 to 6 slices of anything in one sitting. I'm just being honest - So I'll check in next week in 7 days. I used the name SKINNY101 in case anyone wants to keep up with me. I also enjoy reading everyone's progress here."
- Anonymous
- Taken for 1 to 6 months
- December 9, 2018
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "Well, this is my 2nd update. I have now been on Contrave for 8 weeks and have lost 36 lbs. I haven't eliminated much food from my diet, just eat probably less than half of what I used to. I feel so comfortable on this weight management program and don't ever think I am on a diet. Over the 8 weeks, I have gone out for meals many times, I order what I like but just make smarter choices and usually take a doggy bag home and eat it the next day. The only side effect is most of my clothes are too big, but I will gladly buy new ones."
- Sun...
- Taken for 1 to 6 months
- June 19, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I have been taking Contrave for 6 weeks and have lost 16 pounds. For reference, I am 5’4” and weighed 165 lbs. This morning I weighed 149 lbs. Dry mouth and constipation are the only side effects I have now. I will get a headache if I miss a dose (I take 2 pills in AM and 2 in PM). I have to say this medication really works. It doesn’t kill my appetite, but no more binges or overeating. I have total control over my appetite now. Fast food was a big problem for me, but now I don’t really want it. Same with my favorite foods like carbs and pizza — one slice and I’m satisfied. This has really helped me lose weight without suffering through a strict dieting. I found tapering up my dosage over 4 weeks as recommended by the manufacturer really helped with the side effects. For me, the immediate side effects (foggy brain, headache, tiredness, anxiety) went away within a few days of increasing my dosage."
- liv...
- Taken for less than 1 month
- February 16, 2015
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I am currently in week 2 (about halfway through) and have lost 6.6 pounds already. I am quite pleased with that. This has helped greatly to curb my cravings completely and decrease my appetite overall. I haven't had any negative side effects, no nausea, etc."
- Anonymous
- Taken for 1 to 6 months
- January 9, 2024
Contrave (bupropion / naltrexone) "I went from 110 to 160 in 1.5 years or less due to my binge eating disorder. I decided to talk to my family doctor after doing research and was able to get Contrave for free from my insurance, along with the 10% extra they provide, which is awesome. I struggled to take them for the first couple of weeks because they were so big, but I got used to it after a while. They made me very nauseous, and I would have to sit at the end of my bed and breathe for 10 minutes before getting up in the morning. No, you shouldn't drink while taking Contrave. I did once and threw up the next day when I was getting ready for work in the morning. Not a good idea. Contrave completely suppressed my appetite, but I was eating healthy and having 3 meals a day. After losing 40 pounds in 4 months and being back at my pre-binge weight, I went off them and developed healthy eating habits, including homemade meals. I could not have done it without Contrave. It was the best decision I've ever made, to be honest."
- Les...
- Taken for 1 to 6 months
- January 16, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "It doesn't start working right away, so give it at least a month! Bad reviews probably come from people who haven't taken it long enough. After taking Contrave for about six weeks, I now just naturally seem to want healthy food, and junkier food is actually repulsive. I'm also satisfied with far less. I haven't experienced any side effects except an occasional momentary dizzy feeling. Good luck, everyone!"
- Bas...
- August 27, 2016
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I went to my doctor and heard the words 'obese'. It was a huge wake-up call for me. I tried a weight loss program, the Atkins diet, Weight Watchers and when all of those failed, I consulted with a bariatric surgeon. On my first physical for the surgery, he said 'let's try Contrave and if this doesn't help, we will proceed with preparing for the surgery.' That was on June 28th at 5'2, 205 lbs. Today, August 27th, I weigh 164 lbs. My personal goal is 150 lbs. After that, my doctors, nutritionist, and I will evaluate where to go from there. Contrave has changed my life. I've had no side effects and my appetite has reduced drastically. I love to exercise now and love fresh fruit. I will never be able to thank my prescribing doctor enough."
- Vio...
- Taken for 6 months to 1 year
- March 5, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I've tried many products to lose weight over the years. Well, Contrave is awesome. It took a few months before the weight started really dropping, BUT I'M HERE TO TELL YOU IT WORKS! I'm amazed at the weight I'm losing all of a sudden. It just started dropping off. Of course, I'm watching what I eat. Please, if you try it, don't give up. Trust me, it works. Thank you."
- Pre...
- March 19, 2015
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I started Contrave on March 1st, and as of March 19th, I'm down 15 pounds! I'm very pleased with that amount of weight lost. I have not had any side effects so far, so I will continue on. I will check back later and give you an update on what the full one-month total weight loss was."
- Dol...
- Taken for less than 1 month
- June 23, 2019
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I started Contrave 5 days ago and have lost 5 lbs already! I’m excited to see how much weight I will lose on this! Side effects: I felt a little jittery; however, I think this could be from not eating very much. I notice once I eat something, this goes away. Feel slightly ‘out of it’, for instance I can ask someone something and they tell me, and I won’t remember a second later what they said. Very difficult getting to sleep and staying asleep the first couple of days, but it has been getting better by the day. I am nervous about increasing the dose and not being able to sleep again. Increased energy, mild constipation, mild dry mouth. Zero cravings for anything. It makes it really easy to eat clean, avoid carbs, and sugar. I’m not hungry at all. For the first time in my life, I don’t feel like I’m obsessing over food like an addict. I don’t even think about it. When I do eat, I get full really fast."
More about bupropion / naltrexone
- Check interactions
- Compare alternatives
- Reviews (2,061)
- Side effects
- Dosage information
- During pregnancy
- Drug class: anorexiants
- En español
Patient resources
- Bupropion and naltrexone drug information
- Naltrexone and bupropion (Advanced Reading)
- Naltrexone and Bupropion
Contrave (bupropion / naltrexone) for Weight Loss (Obesity/Overweight) "I am on day 5 of taking Contrave. I usually think about food all day, and everything in between is a major inconvenience. Day 5 of this medication, I almost am forgetting to eat. I have more energy, my mind is quieter, I feel overall more peaceful than normal. I've lost 3 pounds already! I get full about halfway through a small meal, which is a big deal for me because usually my appetite is insatiable. I haven't had any of the side effects people have mentioned, except that my eyes feel a little weird, which makes me feel a little dizzy, but it's barely noticeable. I have had some mild headaches, but I think that's because I usually drink a lot of coffee and I haven't craved it as much, so I haven't had as much."