Bupropion / dextromethorphan and Depression: What Users Say

• Anonymous
• Taken for less than 1 month
• March 19, 2023

For Major Depressive Disorder "I wrote a review previously on day 3. I wanted to give an update after day 10 since they advertise it to work by day 7. I rated it a 10/10 then, and I rate it a 10/10 now. I notice that I’m more productive and positive. I’ve kept up with cleaning the dishes, my apartment, and going to the gym. These things are easy for me to do when they once were a pain. I put away small stuff like my plate after I eat instead of just letting it sit there. The only negative thing that I’ve noticed is that at the 6-7 hour mark after taking the first dose, I develop a headache, and I can tell that the medication is wearing off. Auvelity requires you to take two doses a day 8 hours apart. I kind of notice the depression seeping through at around the 7-hour mark, but then it goes away again when I take the 2nd dose. I have PTSD and this med also quiets the ruminating thoughts and hypervigilance."

• Lif...
• Taken for 1 to 6 months
• April 4, 2023

For Major Depressive Disorder "I’ve been on many SSRIs, SNRIs, Wellbutrin, Lithium, Lamictal, Latuda, tried TMS, had 20 IV ketamine treatments. Ketamine worked the first round but not as well the second. Auvelity was a miracle drug for me. I cross-tapered off Wellbutrin while dosing up on Auvelity and felt “high” for 10 days. Cut back to 1 Auvelity at night (off all other Wellbutrin at that point) and that did the trick. No side effects, appetite back, no anxiety, no depression. I haven’t felt this good in 20 years. Only taking 1 Auvelity, nothing else. Insurance covered after submitting a request. I’ve been taking it now for 3 months."

• Dai...
• April 16, 2023

For Major Depressive Disorder "I have been on antidepressants all my life. I have taken all medications available in the market. I started Auvelity 3 days ago. I was told to stop my two other antidepressants the day I started Auvelity. I have an enormous feeling of anxiety and despair. I am extremely depressed, unmotivated, flat affect. I don't want to do anything except hide under the covers. The only problem is that my body won't allow me to relax because I have anxiety and restlessness. It's Sunday. I will stick with the medication, but I think I feel worse."