Rexulti for Major Depressive Disorder User Reviews (Page 4)

• Hikozoe
• December 17, 2015

"I've started taking these along with vybriid and it work really well. Mood swings, controlled, emotions controlled no more feeling sad for any reason. Been taking 40mg of vybrrid and 2mg rexulty, combination is good. No side effects so far. I take them in the am both about 20 to 30 minutes apart from each other."

• Bearsky
• Taken for less than 1 month
• September 15, 2016

"After starting a free sample pack Rexulti with 0.5 mg and 1.0 mg tablets, I noticed a difference within just a few days. Remarkable. The "painful thoughts" all but disappeared. I did another trial pack with the same positive results. I don't know if 1.0 mg is the "therapeutic" dosage but I'll stick with it for now. And NO side effects thus far. We'll see if cost will be an issue as I have MediCal. By far and away the best atypical antipsychotic med I've tried thus far. (I'm also taking Cymbalta and Lithium)"

• Mo712
• September 22, 2015

"I was one of the firsts to try this new medication at my psychiatrists office. I found it to have controlled my emotions. I wasn't crying for any little thing anymore. I noticed my appetite increased, I felt more lethargic and I had sleep disturbances. I chose to discontinue use. It's been 4 days since I abruptly had to stop due to other reasons. I'm still experiencing insomnia."

• MAKen
• December 9, 2018

"This is an intense drug. At first it seemed to be working, I wasn’t prepared for the side effects. My depression seemed better . I had just moved when I first started it. Keep in mind every medication works differently for people. I didn’t think to check the side effects until I had too but I just wasn’t acting like me. The medication had enhanced my anxiety tenfold. The depersonalization and the intrusive thoughts had me to where it was all I could do to recollect myself. I had just moved so I didn't have a regular doctor. The last few weeks I was on this medication were tough. I managed to get into a better place and now know a few reasons why I am strong. I wouldn’t recommend this medication to myself again. This medicine seems to have helped some people and that’s great. Depending on why you take it. Be careful if you interact badly with it be aware of your situation, be aware of the side effects, be aware of who you are in your heart, and be aware that therapy is a lot easier."

• Snovak
• Taken for 1 to 6 months
• April 7, 2021

"Rexulti made me feel the best that I had in years. However it made me want to eat myself to death and I was left with permanent body movements. My legs can't be still and my hands shake all of the time. Very frustrating."

• Mytik...
• May 14, 2016

"Been on this med for 5 weeks. First of all the med definatly has helped my mood. I have been feeling mentally fantastic like I had felt 10 years ago before being depressed. All cobwebs gone thinking clearly and getting everything done and accomplished . Well this is where the down fall starts. Cant stop moving until I am so tired I pass out.I do sleep well and through the night but only seem to need less than 6 hours verus 8 in the past. Legs, feet, arms and hands hurt. They tingle with numbness, feel heavy as bricks weak and rubbery and so swollen I cant hold anything or walk. I am picking up a deep cough and my throat is starting to feel closed up. It was nice to feel clear happy and not depresssed for this time but I need to walk."

• Dissa...
• Taken for 1 to 6 months
• July 18, 2016

"I suffer from mdd, anxiety and PTSD. I added rexulti to my lamictal 100mg. I started at .5mg and progressed to 2mg. I had tried 15 different medications in the previous year all with no effect or i had adverse reactions. I noticed an immediate difference in my mood on rexulti. It helped me go from completely non functional to the ability to get out of bed, shower, do laundry etc. Now the bad news. I was extremely restless and had trouble sitting still, I had vivid dreams and nightmares, I gained 15 lbs in two months and the worst part is it gave me high blood sugar. I was not willing to add diabetes to my list of diagnoses so I immediately discontinued this medication. I was disappointed this was the first medication that seemed to help"

• Gmarie
• March 7, 2017

"So far I've been loving the way this med has effected my depression and anxiety! It's helping me function normally. Things have gotten a lot better since taking rexulti and I highly recommend it to anyone struggling with MDD. I can only hope it continues to work for me! I've had some minor side effects, but nothing terrible."

• Mr Ji...
• October 12, 2019

"I’ve been on several different mood stabilizers and Rexulti has been by far the best for my mood. That being said it has also made me gain a tremendous amount of weight in a short time. 25 pounds in the first 2 months with no signs of slowing down. I’m on long term disability so I’m not very active. I go for walks and avoid fast foods but it doesn’t seem to matter. This drug is good and bad hence the 6 out of 10 rating"

• Penel...
• January 16, 2019

"At first, I thought this was the miracle drug. I felt incredible and felt like my old self again. I had motivation, I was able to get so much more done in a day! I didn't feel like a zombie. I was a able to stop having to take a daily nap. After 2 weeks, my clothes didn't fit right. On week 4, I got on the scale. WHAT??? I gained 9 pounds. Clearly I am quitting rexulti ASAP"

• Chas
• Taken for less than 1 month
• June 22, 2023

"Rexulti has been a nightmare for me. I was prescribed 1mg as an add-on to paroxetine 40mg for drug-resistant depression, and I was so hoping it would work. The first few days were okay, but then I began to have side effects, including nausea, diarrhea, a stiff neck and a horrendous feeling of inner tension akin to anxiety without the thoughts. Two weeks in I decided the side effects were too overwhelming, and I stopped taking it. Unfortunately, Rexulti has a half-life of 4 days! So even though I have been off it for 8 days, the side effects continue. I hasten to add I am one of these individuals who tend to experience side effects so it may be different from you. For me, Rexulti has been horrendous."

• Survi...
• Taken for 1 to 6 months
• August 20, 2019

"It started out pretty well. I was feeling great. I had an appetite. Within a few days I felt my manic depression even out. Then a few days later I started not being able to sit still or concentrate. 3 weeks later I landed myself in a triage appointment at my doctors because I was having so much anxiety I was sick and couldn’t see straight. The doc said I had an adverse reaction -akathisia where you can’t sit still and you’re shaking constantly. This was abnormal because I already do that but it was way worse. Now I’m on all sorts of meds to get me to calm back down until I can get into therapy. I would not recommend this to a person with anxiety."

• Bob
• Taken for 1 to 6 months
• May 26, 2019

"Self hatred, lack of family interaction improved positively. Experiencing some side effects of restless, but I am aware of the period of time for the body to adapt. My family doctor is closely monitoring me."

• eyede...
• Taken for 1 to 6 months
• July 18, 2017

"Started this medication about 4-5 weeks ago. I'm on 1 mg. It's an add on to my Viibryd 60mg and Buproprion SR 200 mg. This pill has really worked great for me. It's given me energy and the motivation I need to get stuff done. My family has noticed the difference. On the downside is that I am restless and it's given me a bit of insomnia. My doc told me we can solve that by taking the dose as soon as I wake up. I start that tomorrow am. It's also made me want to night binge eat snacks more than ever. But I've learned my lesson with past medications and make sure never to have snacks available at home. So far so good. I'm making progress with my medication, psychiatrist, and psychologist. I have hope."

• Effec...
• Taken for less than 1 month
• February 10, 2019

"This medication helped a lot when I took it as a sample, but when my pharmacy called to tell me even WITH my insurance, the cost would be over $700.00 for a month’s supply.. it obviously wasn’t an option for me anymore. Who can afford that?!?"

• D2yorkg
• Taken for less than 1 month
• February 5, 2016

"HESITATING, began treatment tonight. I suffer PTSD, being able now, for the first time in decades, to come close to admitting how I have been living a marginal life at best. If you suffer trauma, war, hostage, abuse, neglect, torture, etc.and have been prescribed this medication,please send feedback. Thank you. I would be delighted to live some part of my life without reliving constant terror."

• MGY
• August 17, 2016

"I started on Rexulti four months ago. I take 1.0mg Rexulti along with 160mg of Duloxetine. My first reaction was tremendous energy and a much better mood. The crying episodes have stopped completely.The energy level soon returned to normal and now I am feeling very tired and fatigued. I generally fall asleep right away but awake at 3:00am just like clock work. I stay in bed until 6:00am. Weight gain has not been a problem although I admit to feeling hungry all the time. The benefits of this drug far out way the negative symptoms. I also suffer from anxiety disorder and Rexulti has helped with that as well. The cost of this drug is very high. Hopefully as time goes on it will come down. My doctor provides me with samples for now."

• Angie
• Taken for 1 to 6 months
• July 16, 2019

"Was put on Rexulti to help with the Wellbutrin I’m on and Pristiq. I wasn’t happy to be prescribed this medication after looking at the side effects. My psychiatrist said that she will run a cholesterol panel to make sure that it’s not going up. Unfortunately after I started taking this medication I felt floating head (if that makes sense). I was almost falling asleep at the wheel driving around 4pm-7pm. I should not be this tired. At this time at all. It’s never happened to me before. I stopped taking it and I’ll be asking my doctor for a different prescription. I will be doing my research."

• Anonymous
• April 24, 2016

"I am writing this review as I just returned from Emergency Room with my sister for the second time in a week after she was prescribed Rexulti for depression. She felt fine the first two days and about the 6th day she was a mess. She has been off the medicine for 10 days now and is still experiencing an adverse effect. She is having violent uncontrollable shaking in her legs. She is experiencing numbness in her tongue and her speech is very slurred, probably because it seems as though her tongue is also swollen. She was given a shot of ativan, a steriod, and shot of phenergan. We were told these symptoms could last from 6-8 weeks. However, the ER doctor said sometimes these symptoms are irreversible. I pray that is not the case."

• squid
• July 11, 2016

"Have been taking for three weeks now and feel better than I have in years. Also take Wellbutrin, Viibryd and Lamictal, they worked fairly well but never felt 100% and I recently started slipping into a very bad place. Doc reduced Wellbutrin from 450 mg/day to 150/mg a day and added 1mg Rexulti, only a few weeks but noticing a huge difference. Only side effects so far are stomach upset (went away in a few days) and it really increased my appetite at first (great, just what I need), but seems to have leveled off. I take it at bedtime so haven't had any problems with drowsiness."

• sincere...
• January 13, 2016

"I started this medication 5 days ago. I get so hot burning hot and very sweaty. My anxiety level has increased bringing me to the ER twice in one week. My appetite has increased. However, I am a lot happier everything is so clear , everyone notices the difference in me. I have become confident AGAIN the first time in 15 years... I hate to discontinue ....."

• Vic
• Taken for less than 1 month
• January 3, 2020

"I had panic attacks and suicidal ideation, so I was prescribed Rexulti with my anti depressants. I had a panic attack flying, which never happened before, both to and from the location. I had a panic attack after a movie. I had a panic attack at night in bed. I have never had suicidal thoughts before, luckily, but there's been four clear incidences where I've had thoughts. I've been on it for four weeks."

• Hopeful
• April 16, 2021

"After a sudden crisis of anxiety and paranoia, very schizophrenic-like, I was admitted through ER to high-security psych ward. Was discharged two weeks later with several anti-psychotic meds that enabled me to go home where I have amazing family support. Struggled for 5.5 years, trying a host of different meds, none of which helped much and many made me feel worse. 6-7 months ago I began Rexulti and after the first 2 weeks on 1mg, noticing improvement, we increased to 2mg and within 2 days I got my mental and emotional game back. My family could not believe the difference. It was no placebo, as we had all but given up on meds being helpful. I have gained 10lbs of belly fat, but the trade-off has been well worth it. I'm far from sure the benefits will last, but it's been wonderful to become functional and more at peace again, so I can continue to identify and address the deeper psychological factors underpinning my challenges here."

• Vano
• Taken for less than 1 month
• September 3, 2018

"The doctor said it would work fast if it’s going to work. I finally feel like my old self, before all the stress and trauma I had years ago, which I believe triggered my condition. Abilify worked before but it’s too expensive. I never thought I’d have my concentration and memory and happiness back! But it’s here!"

• KMF
• Taken for less than 1 month
• November 4, 2020

"I have MDD and am on Vyvanse 60mg, Trintellix 20mg, just added Rexulti 1mg today. I have not found anyone on this regimen. Most days, it was difficult to get out of bed. I could not focus on small tasks, lack of desire to do anything I once loved and enjoyed. Does anyone else take this regimen and can you share your experience? Rexulti day 1, stay tuned."