Amoxicillin / clavulanate and Anxiety: What Users Say

• Son...
• Taken for less than 1 month
• February 18, 2020

Amoxicillin / clavulanate for Sinusitis "I started taking Augmentin and had a panic attack that very night. I had never had a problem with anxiety or panic attacks. I had my medication changed. Later on, I got another sinus infection, and was told that Augmentin couldn't have given me a panic attack, so I decided to listen to them and give Augmentin another try. Well, guess what, another panic attack. Those were two of the scariest experiences of my life. I couldn't breathe, I was trembling, chest pounding. Doctors need to listen to patients more and not think that they know everything about a medication just because research hasn't shown it yet."

• GSa...
• Taken for less than 1 month
• January 23, 2021

Amoxicillin / clavulanate for Bacterial Infection "Taking Augmentin 875/125 2x daily prophylactically to prevent infection from a deep puncture cat bite. Five days in, there is no sign of infection, and everything appears to be healing fine. So, it seems to have potentially prevented infection. But wow, did it make me feel awful. Brain fog with difficulty focusing mentally and visually. No energy. Lots of nausea, lack of appetite, and generally feeling out of it. Diarrhea occurs without enough fiber. As others have said, I think it's increased my anxiety significantly. Haven't had any panic attacks for a long time, until this beauty. I'm not sure I'll ever know if it prevented an infection or not. I do know that it caused me to feel like absolute crud!"

• Dan...
• Taken for less than 1 month
• October 2, 2019

Amoxicillin / clavulanate for Bacterial Infection "After taking this drug for 2 days, I had uncontrollable anxiety and ended up in the emergency room with a blood pressure of 190 over 100. This drug has caused panic attacks and anxiety. I will never take it again."

• Lau...
• June 12, 2017

Amoxicillin / clavulanate for Urinary Tract Infection "Feeling horrendous, like I'm being poisoned! Was prescribed this after a trip to A&E with an upper UTI/kidney infection. I don't normally take meds, and I'm trying to avoid antibiotics as I have leaky gut, but the Dr urged me to take them as the infection was so bad. Anyway, the first day or two weren't too bad, but then I woke up and felt like I'd been hit by a freight train. Here are some of the things I've been experiencing: nausea, bloating, thrush, severe migraine-like headaches, loss of appetite, depression and mood swings, paranoia, anxiety, dehydration due to constant urination, burning pain in my limbs and a stiff neck, a feeling of being hungover each morning, dizziness and 'brain fog,' and a dry cough! Never taking these again!!!"

• sar...
• August 23, 2019

Amoxicillin / clavulanate for Bacterial Infection "This medication is freaking me out! I have sinusitis, a chest infection, and a bacterial infection. All my thoughts are super negative and snarky. I have constant anxiety and feel like doing push-ups and running a mile, but I am sick, so I can't. I can't sleep and am having hallucinations. It is, however, the only antibiotic that seems to work for me. I have an immune system disorder (hypogammaglobulinemia) and get bacterial infections anywhere often, particularly chest and sinus. Do I suck it up? Double up on antidepressants? Or 'just breathe' to lower my anxiety? ... Totally freaking out and trying not to rage. I am going to have to take time off work so I don't offend someone and ruin my career."

• Bea...
• Taken for less than 1 month
• December 15, 2018

Amoxicillin / clavulanate for Bacterial Infection "Prescribed Augmentin fairly frequently for diverticulitis (as I suffer from autoimmune neutropenia too, I am on a lower threshold for treatment as the risk of life-threatening infection is high). I always feel better after two days, but that's when the gates of hell open and the side effects knock me out completely. If I don't take in enough fluids, my kidneys feel like they'll explode, I feel so incredibly weak and lifeless, it gives me a constant headache for the duration of treatment, nausea, no appetite, diarrhea, intestinal pain worse than what it's supposed to treat, and it causes my emotional state to deteriorate severely - I can't stop crying and feel so very stressed, agitated, and anxious."

• Bea...
• Taken for less than 1 month
• December 15, 2018

Amoxicillin / clavulanate for Bacterial Infection "Prescribed Augmentin fairly frequently for diverticulitis (as I suffer from autoimmune neutropenia too, I am on a lower threshold for treatment as the risk of life-threatening infection is high). I always feel better after two days, but that's when the gates of hell open and the side effects knock me out completely. If I don't take in enough fluids, my kidneys feel like they'll explode, I feel so incredibly weak and lifeless, it gives me a constant headache for the duration of treatment, nausea, no appetite, diarrhea, intestinal pain worse than what it's supposed to treat, and it causes my emotional state to deteriorate severely - I can't stop crying and feel so very stressed, agitated, and anxious."

• bab...
• Taken for 1 to 6 months
• June 11, 2019

Amoxicillin / clavulanate for Sinusitis "I was prescribed this by my doctor for sinusitis. I’ve been on all types of antibiotics in my life, and this stuff is horrible. Went on my lunch break, and I was convinced I was dying. Anxiety, panic attacks, tarry stool (gastric bleeding?), chest and back pain, side pain, chest tightness, abdominal cramping (felt like something was tearing into my stomach), sweating, terrible diarrhea, pale, dizziness, huge headache, etc. Only took one dose, stopped dosage, and called my ENT doctor for an appointment."

• bal...
• Taken for less than 1 month
• February 6, 2020

For Sinusitis "Do not take this amoxicillin/clavulanate if you suffer from panic attacks or anxiety. I have been feeling like I’m losing my mind and constantly crying and having the worst thoughts. I didn’t know where it was coming from, but it all makes sense now after reading other reviews. Don’t do it."

• Chr...
• Taken for less than 1 month
• March 11, 2020

Amoxicillin / clavulanate for Sinusitis "I was recently prescribed Augmentin 875 mg two times a day for 10 days for a very severe upper respiratory/sinus infection. On day one, I had pain in my head, some sweating/chills, lethargy, and stomach upset. Day two, I had bad diarrhea, anxiety, nervousness/agitation, sweating/chills, and some tiredness. Day three, I had all of the above, as well as developing one hive on my right arm after my evening dose. The medication helps my sinus infection, but the side effects are troubling. I do not feel good for at least two or three hours after taking this medication."

• Ste...
• September 11, 2019

Amoxicillin / clavulanate for Sinusitis "Was prescribed Augmentin for a sinus infection, and my anxiety has been crazy (already diagnosed with anxiety, and it seems to be worse). My throat felt worse before it got better. I'm also having headaches, nausea, and loose bowels. I can't wait to be done!"

• Hat...
• Taken for less than 1 month
• February 20, 2019

Amoxicillin / clavulanate for Sinusitis "I was prescribed this from the hospital for sinusitis. I’ve been on all types of antibiotics in my life, and this stuff is horrible. Woke up this morning convinced I was dying. Anxiety, panic attacks, tarry stool, chest and back pain, side pain, chest tightness, abdominal cramping, diarrhea, pale, dizziness, headache. I could go on. Stopped dosage and heading to PCP tomorrow to figure out what’s going on now."

• Jef...
• Taken for less than 1 month
• May 28, 2018

Amoxicillin / clavulanate for Bacterial Infection "I took it for a severely abscessed tooth. It did clear up after 5 days (2 1000 mg tabs a day). However, I felt horrible the entire time. Gave me so much anxiety that I had 2 panic attacks. I had headaches, stomach pain, and diarrhea. No appetite, even though you have to eat in order to tolerate the medicine. My infection was really bad, and I'm thankful that the Augmentin cleared it up, but I'm not sure if I would be willing to take it again."

• Lem...
• January 26, 2020

Amoxicillin / clavulanate for Sinusitis "Sinus infection had green mucus and coughing green mucus. I take antidepressants and benzodiazepines for anxiety. I’ve taken Augmentin for three days, my anxiety is out the roof, feels like my depression is awful. I’ve been crying. I’m not taking Augmentin again. It works for sinus infection, but the side effects are too much for me."

• MsE...
• Taken for less than 1 month
• March 8, 2016

Amoxicillin / clavulanate for Upper Respiratory Tract Infection "I've been on Augmentin for 7 days now. It is helping my upper respiratory infection, but I'm having anxiety and very loose stools (very dark diarrhea). Also, my heart beats faster than normal too. I've only got 3 days left to take it. I'll be glad when it's done. I also feel fatigued and have a little blurry vision. My body is very sensitive to drugs. But despite all that, I do feel it has helped with the upper respiratory problem. I'm just ready to feel better and healthy!"

• Sco...
• Taken for less than 1 month
• June 5, 2018

For Sinusitis "Had post-nasal drip, sinus swelling, ear, and toothache diagnosed as a bacterial infection. I was skeptical, but I assume that doctors know what they're about. Initially, the swelling went down, but after a few days, I began to notice mild paranoia, nervousness, and headaches. After 7 days, it was hard for me to hold down food or sleep. My gut is swollen, and I am alternating between panic attacks and severe depression. I have missed more work due to the medication than I did for the sinus problems. I hope this abates soon after I'm done. 2 pills left, and I will never take this again unless I need it to save my life."

• Sjr...
• November 9, 2015

For Bacterial Infection "When I first started the medication, it did not affect me the first two days, and then I started having anxiety, nervousness, depression, tiredness. My stomach felt weird, and I just didn't feel like myself. I had an upper respiratory infection, which is better. I have one more pill to take tonight, but I am skipping it because I have had such a bad day. I was on the 875 mg for seven days, twice a day. I will ask the doctor for something else next time. From what I'm reading, I think it is the clavulanate ingredient, and I also spoke to the pharmacist, and he said that that gives it an extra kick to kill the infection. So this is a super strong antibiotic and has side effects that I've never experienced before with an antibiotic."

• Sjr...
• November 9, 2015

For Bacterial Infection "When I first started the medication, it did not affect me the first two days, and then I started having anxiety, nervousness, depression, tiredness. My stomach felt weird, and I just didn't feel like myself. I had an upper respiratory infection, which is better. I have one more pill to take tonight, but I am skipping it because I have had such a bad day. I was on the 875 mg for seven days, twice a day. I will ask the doctor for something else next time. From what I'm reading, I think it is the clavulanate ingredient, and I also spoke to the pharmacist, and he said that that gives it an extra kick to kill the infection. So this is a super strong antibiotic and has side effects that I've never experienced before with an antibiotic."

• Ana...
• Taken for less than 1 month
• November 8, 2019

Amoxicillin / clavulanate for Upper Respiratory Tract Infection "I have really bad anxiety about eating things in general, I have always struggled with this. However, when I started taking Augmentin, not only did it greatly improve my infection, it made me really relaxed, so much that I was finally able to eat whatever I liked without worrying about it. I ended up eating normally like I should, and everything was perfect. Unfortunately, I had to stop taking it at some point, and my anxiety came back a bit worse than it was before. I've been seeing really bad reviews for it, but I've only ever had great experiences. :)"

• Bab...
• Taken for less than 1 month
• January 5, 2019

Amoxicillin / clavulanate for Sinusitis "I was given this by an ER doctor for sinusitis. I took the first dose at the ER then didn't get a chance to fill the prescription for a week. Was still feeling a little bit of ear congestion from sinusitis, so I grabbed it. The first pharmacy dose gave me nonstop diarrhea and severe nausea, like my stomach was going to explode. So now, I drink probiotic yogurt with a full meal. Took it 2 more times, not as bad but constant anxiety. Had to stop, as I felt worse when taking it. Head congestion is pretty much gone, though I just decided to take Mucinex, and I feel like that has helped even though I'm still dealing with it a bit. Never taking it again."

• Ter...
• Taken for less than 1 month
• January 9, 2022

Amoxicillin / clavulanate for Bacterial Infection "This has been a terrible experience. Given 875 mg for 7 days for diverticulitis. Side effects are extremely tired, anxiety, complete loss of appetite, bloating, and full of gas, extreme weakness in legs, feel like passing out. Worse than the problem it was for. One more day left and feel like passing on it. Hopefully, I will bounce back after it is out of the system. Unless you can lay around and not have to function, I would not take. Could barely take a shower, was so tired. In my opinion, bad stuff."

• Bet...
• Taken for less than 1 month
• January 23, 2020

Amoxicillin / clavulanate for Skin or Soft Tissue Infection "I was prescribed Augmentin for what my doctor thought was a skin infection on my right leg. Well, after taking my first dose, within 2 hours, my stomach became extremely upset... burning... nausea... diarrhea... bloating... and anxiety and panic have always been an issue for me, but after Augmentin, it was immediately 20 times worse. My doctor ended up telling me to stop taking it on day 5 because it was getting worse and worse. My skin infection cleared up with some hydrocortisone cream and antibiotic ointment, but it's been over 3 months since stopping this medication, and I'm still having major stomach issues and mental issues, so please be careful, people, especially if you have anxiety or stomach issues beforehand."

• Anonymous
• August 25, 2020

Amoxicillin / clavulanate for Urinary Tract Infection "This is a strong antibiotic, and it’s horrible on the stomach. After only a couple of hours, my entire stomach was hurting very badly, with severe diarrhea and anxiety. I switched to Keflex, hoping it’s better."

• kka...
• January 13, 2021

Amoxicillin / clavulanate for Bacterial Infection "Taking this for an unknown bacterial infection - confirmed with CBC, but I personally suspect it's early onset of appendicitis. I'm on a pretty high dose according to my doc (500 mg 3x daily), and oh man. The brain fog is maybe the worst symptom. It starts in about an hour after taking it and settles in for a few hours. It just feels hard to focus on anything, like my vision is blurred almost. Between that and the insomnia, nausea if I eat food anytime between doses, and diarrhea, what a fun medication!! Loss of appetite too I've noticed. I think it's increased my anxiety too, but I'm a bit of a hypochondriac to begin with, so I don't know, my anxiety might be increased just because this drug is whacky. I'm on this thing for 10 days. Today is day 3. Noticed an improvement in my infection symptoms I think? Much less abdominal pain, but it's hard to get a good gauge on that when you're having diarrhea so much!!"

• Che...
• Taken for less than 1 month
• July 27, 2018

For Sinusitis "Took this medication for 5.5 days. I do not have anxiety or panic attacks, but this medicine brought them on. Will never take this again, and I will not finish my prescription. It was awful, I have never felt like that before, nor do I ever want to again! Also felt like my heart was going to beat out of my chest, couldn't eat, absolutely no appetite."