Endep User Reviews & Ratings (Page 2)

Endep has an average rating of 6.8 out of 10 from a total of 8 reviews on Drugs.com. 58% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Endep

pinky
Taken for 1 to 6 months
December 26, 2019

For Depression "My Father has been on Endep (low dose) for a few months and has slept 20 hours a day however he is pain free for the first time in a long time. I don't now if the trade off is worth it but his pain unbearable, but now he has no life. Just sleep."

6 / 10

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25 Report

aaaaa...
January 6, 2017

For Insomnia "Works ok. I have Bulge discs, tear, depression & anxiety . On this I sleep well. Loss of sex drive, anxiety and stress still high. Doesn't help the pain so much in my back. I sleep really well at night after 100mg, but I wake up tired and need to nap for 2-3 hours and in bed by 9:30pm. Just always wanting to sleep and lazy."

5 / 10

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34 Report

Chriso
October 22, 2016

For Anxiety and Stress "Been taking it for 6 years initially for depression then anxiety and stress and it's one of the worst things to happen to me. Constant eczema where my skins gets very itchy and sore that I have scars all over, constipation is probably the worst as I've had periods of vomiting to stomach being sore and bloated, blurred vision, it's addictive contrary to what doctors say as I have been trying to get off it for 2 years slowly and been admitted to hospital twice in that time for substance abuse relating to endep. Doctors can't understand why I have been on it for so long. Take mine at night as you get drowsy of a day on higher than 50mg (most I taken was 75mg) now on 10mg and still get constipation."

1 / 10

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30 Report

Frequently asked questions

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Son
Taken for 1 to 6 months
October 4, 2019

For Chronic Myofascial Pain "This medication should not be taken lightly. It has some terrible side effects I’m taking this to help with my burning mouth syndrome (BMS) which has bought on anxiety. If it wasn’t for my BMS I would never take Endep. People should be aware of the side effects this medication can have as it’s made me sick, once I take the medication any higher than 75mg I know the side effects will come on (shortness of breathe, chills etc) I’ve woken up many of nights in chills and fever in my chest and I’ve taken myself to hospital as I thought I was going to die. The latest I’ve woken up with tremors and taken by ambulance to hospital."

1 / 10

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20 Report

Pattie
March 15, 2018

For Depression "I dropped 50mg of Endep cold turkey over 3 years ago. I ended up with 24/7 migraines for a month, collapsed and was taken to Hospital and unfortunately the Doctor started me back on Endep He said they were good for Headaches. Left Hospital on a small dose and started having Panic Attacks all day every day, collapsed and was put back in Hospital. They increased my Dose of Endep. I am now trying to get off it again as it is not working, I am decreasing the Endep by 5mg a week."

1 / 10

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21 Report

Are you taking this medicine?

JTano
Taken for less than 1 month
July 28, 2018

For Interstitial Cystitis "I have to say that Endep is simply wonderful in shutting down the symptoms of interstitial cystitis (IC) BUT the side effects are horrendous. I have tried for 5 days but every day I feel worse. So I have given up . I will go back to Ditropan and try increasing the dose. If the people who make Endep ever read this , PLEASE do something to reduce the side effects because this is such a wonderful medication for those of us who have IC, but the side effects are just to much to deal with."

5 / 10

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20 Report

JJano
Taken for less than 1 month
January 30, 2021

For Fibromyalgia "Two days after taking Endep 10mg, 50% of my pain was gone. Lasted three days then the pain came back. Up the dose to 20mg and pain reduced again but legs feel twitchy and restless in the day. A weird feeling, usually happens at night. Will keep trying and see if it goes alway. Next step up to 30mg. So far it’s better than being in constant fibromyalgia pain 24/7. It did take 4-5 days to get use to sleep side effect. Within an hour of taking go straight to bed and try and sleep. Able to sleep with only waking once. Does make you tired in the morning but again it’s better than the pain. Worth a try. Good luck"

8 / 10

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10 Report

crystal...
Taken for 1 to 6 months
February 5, 2023

"I have had chronic Urinary tract infections (UTIs) for over 50 years. I have vesicoureteral reflux which has atrophied my right kidney, my last scan showed it to be 45mm and I've had occasional sepsis. I also have Rheumatoid Arthritis, Fibromyalgia, and anxiety. Recently my rheumatologist put me on Endep initially 50 mg a day and increased it to 200 mg a day over a few months. After waking constantly to go to the bathroom at night I am now sleeping through the night. I wished I had tried this sooner."

10 / 10

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4 Report

Gina...
Taken for 6 months to 1 year
December 20, 2021

For Insomnia "Fed up with 10 years of insomnia after menopause commenced, my doctor started me on Amitriptyline earlier this year (2021). I have been taking 50mg in the evening & sleep soundly. No more 2-3am awaking or tossing & turning. I wish I found my current doctor years earlier as this medication has been a lifesaver. I've only gained a small amount of weight but that's my own fault for sometimes snacking during the evening."

10 / 10

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5 Report

Raysa
Taken for 1 to 2 years
April 7, 2018

For Pain "I got shingles in December 2016 and have been on and off endep since then. It helped my shingles pain but I get very little sleep. I have to make a choice of not sleeping due to pain, taking endep and have no pain and still not sleep. If there was a natural alternative I'd use that but I've been told that there isn't any. I take Axit for my PTSD and OCD, plus norflex for my grinding teeth at night. I've had insomnia since I was a kid and refuse to take sleeping pills again."

4 / 10

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9 Report

Anonymous
December 17, 2011

For Fibromyalgia "Endep had a very quick effect and eliminated the muscular pain that I have suffered for more than ten years. I do feel drowsy, it seems to have a calming effect on me and I sleep amazingly well."

10 / 10

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131 Report

Chewy...
July 12, 2013

For Pain "Was prescribed Endep 10 for the pain associated with an attack of Shingles. The effect was very good as I had very little pain from the rash or the nerves affected by shingles."

9 / 10

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107 Report

Megat...
July 29, 2013

For Pain "Started taking 10mg then up to 25 for severe long term migraines/ headaches. Meds work well, am considering lowering dosages and getting off medicines all together to start family now though."

8 / 10

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93 Report

Anonymous
Taken for 1 to 2 years
October 19, 2016

For Fibromyalgia "Wonderful for my fibromyalgia. It helps reduce pain and helps me get a solid nights sleep. I take 50mg 2 hours before bedtime. Recommend this highly."

10 / 10

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71 Report

Abdol...
August 5, 2016

For Depression "i use endep for 14 years for my depresion it is very good for me i take 100 mg every nighte i fill verey good and sleep verey nice and good no thinking no sad just i be relax thanks my god"

10 / 10

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71 Report

Night...
Taken for less than 1 month
October 1, 2020

For Pain "Endep worked for pain 100% but put me in a mental ward Destroyed my life Get tested to see if you are, allergic to amitripyline first It was very dangerous for me I only had 13 tablets"

1 / 10

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36 Report

Me...
September 13, 2015

For Anxiety and Stress "Dramatic weight gain, heartburn, sleeplessness"

1 / 10

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66 Report

Skip
Taken for less than 1 month
August 18, 2020

For Pain "Endep gave me the worst side effects I've ever had from a medication. I was like a zombie and I was only taking 5mg. Would never take it again. It also made my pain worse"

1 / 10

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29 Report

Sleep...
Taken for 10 years or more
April 12, 2020

For Insomnia "I've been on endep since 2009 for insomnia I'm on 100mg a night and while I don't have any bad side effects it only works 95% of the time."

8 / 10

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30 Report

Ehlers
Taken for 10 years or more
March 24, 2020

For Insomnia "25-75mg. Have taken endep on & off for years with great results. It’s definitely my go-to medication for insomnia. Have never noticed any relief with my nerve pain though."

10 / 10

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29 Report

Chris...
Taken for less than 1 month
July 31, 2018

For Fibromyalgia "Have been on this for 2 days now, first and second night, best sleep ever...wait & see !!!"

10 / 10

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28 Report

rlltr...
Taken for less than 1 month
July 28, 2015

For Insomnia "I take Endep for depression. If I take it in the evening or at night I cannot sleep at all; just toss and turn all night. Therefore, I only take it in the morning."

1 / 10

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33 Report

Frann...
October 13, 2015

For Fibromyalgia "I'm on 150 and it doesn't do anything"

3 / 10

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11 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.