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Endep for Depression User Reviews

Endep has an average rating of 6.8 out of 10 from a total of 6 reviews for the treatment of Depression. 50% of reviewers reported a positive experience, while 17% reported a negative experience.

Endep rating summary

6.8 average rating out of 10

6 ratings from 8 user reviews.

Compare all 184 medications used in the treatment of Depression.

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  • For...
  • Taken for 10 years or more
  • June 15, 2020

"I have been taking Endep for well over 12 years without any side effects whatsoever. It has helped me greatly. My maintenance dose is 100mg. It also helps my pain, as well as being able to get about 6 hours of sleep at night. I am an elderly person, but Endep has contributed to giving me a better quality of life."

10 / 10
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95 Report
  • Abd...
  • August 5, 2016

"I have been using Endep for 14 years for my depression. It has been very effective for me. I take 100 mg every night. I feel very good and sleep very well. My mind is clear, I am not sad, just relaxed. Thank you."

10 / 10
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75 Report
  • Lor...
  • December 8, 2007

"I have only just started using Endep after the sudden onset of a severe depression. I found that it has helped me a great deal. The only side effects that I've had up to this point are a gain in weight (as I wasn't eating properly when depressed) and at night, I'll wake from sleep covered in perspiration - though only from the chest up. I'm hoping with counselling I'll be able to stop taking this medication asap, but it has been a great help. Thanks :)"

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126 Report

Frequently asked questions

  • poe...
  • May 23, 2016

"I have only been on this drug for two weeks, and as yet, I have not noticed any difference with my depression. My anxiety levels are up, I have swooshing, buzzing noises in my ears. I even feel dizzy while seated and even just turning my head from side to side. I have noticed tingling in my fingers. My balance is affected, feeling like a drunk person. My head throbs."

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70 Report
  • See...
  • Taken for less than 1 month
  • April 7, 2018

"I've been on probably every SSRI except Prozac, which all had short-lived outcomes. Finally, after 20 years, I've been put on an SNRI, and it's working. Started on 10 mg Endep for appetite, which didn't work, and given Valium for the shakes and tears. Valium stopped working in less than 2 weeks, so I stopped taking it, and the psych increased the dosage of Endep to 25 mg, and I'm actually feeling good. After 6 months of awfulness, this might be my answer. Sleeping well, lots of energy, memory and concentration are better, and no more teeth grinding. No real side effects except for the first day I started on the 10 mg, I copped a bad headache, but that was it."

10 / 10
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54 Report

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  • aff...
  • Taken for 1 to 6 months
  • October 15, 2015

"I was on 75 mg of Endep and noticed two extreme side effects, which led to me having to stop taking the medication. The first was rapid and excessive weight gain; I gained 6 kgs (13 pounds) within 8 weeks (at 160 cm, this is quite a bit of weight). I had no change in my diet; my exercise stayed the same, so the Endep was the only thing that could have caused the weight gain. The second was extreme night terrors. These occurred every night and were extremely frightening for myself and family, as I would wake up screaming and kicking every night. This occurred almost immediately after starting the Endep. Since stopping the Endep 2 weeks ago, the night terrors have ceased completely, and I have lost 1 kg with no change in diet."

4 / 10
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58 Report
  • pin...
  • Taken for 1 to 6 months
  • December 26, 2019

"My father has been on Endep (low dose) for a few months and has slept 20 hours a day, however, he is pain-free for the first time in a long time. I don't know if the trade-off is worth it, but his pain was unbearable, but now he has no life. Just sleep."

6 / 10
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26 Report
  • Pat...
  • March 15, 2018

"I dropped 50 mg of Endep cold turkey over 3 years ago. I ended up with 24/7 migraines for a month, collapsed, and was taken to the hospital, and unfortunately, the doctor started me back on Endep. He said they were good for headaches. Left the hospital on a small dose and started having panic attacks all day, every day, collapsed, and was put back in the hospital. They increased my dose of Endep. I am now trying to get off it again as it is not working, I am decreasing the Endep by 5 mg a week."

1 / 10
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22 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.