Praluent User Reviews & Ratings (Page 5)

• Lon
• Taken for 1 to 6 months
• July 20, 2018

For High Cholesterol "After 15 years on statins I could not accept Iiving with the continuous aches and pains. After three months on Praluent I feel fine, no noticeable side affects, no problem with injections. Cholesterol numbers reduced dramatically."

• Jrano
• Taken for 5 to 10 years
• January 24, 2019

For High Cholesterol "Awesome stuff for me. No side effects. Cut the pravastatin in half 40mg pravastatin 1x daily plus 75mg alirocumab every other week HDL down from 399 to 85mg dl. Still taking the other stuff. Livolo works fairly well but not like this. Can't tolerate ACE inhibitors and some med put a bruise across my back within three days. instant kidney damage. Now blue cross wants to deny me the only med combo I could tolerate. Actually prime theraputics is doing that. Forwarding their denial to cardio and via my atty to oag and state insurance board. After one 4x cabg 3 stents 2 mi. Bilateral endarectomy and original LDL around 400. I think my widow will be a millionaire as for ME.. we can prove this is the best and most correct treatment plan and it did work for about 5 years until they decided they should play doctor..."

• Kiki
• Taken for 1 to 6 months
• April 22, 2024

For High Cholesterol "I have had a good experience with Praluent and although my cholesterol has come down significantly, my provider increased my dose to get my LDL lower because I have a high calcium score. I had a rash around the injection site with the first few injections and my face would get really flush but that didn’t happen with the last injection, so my body must be getting used to the injection."

• ziggy
• Taken for 1 to 2 years
• November 1, 2016

For High Cholesterol, Familial Heterozygous "35 year history here of familial high cholesterol. Participated in medical studies many of these years-first for new statins, then other drugs. Lowest my overall cholesterol went was 259, that with max dose of Crestor and Zetia combined. Took that before and after triple bypass and stent on the 4th artery. Eventually all statins cause too much muscoskeletal pain for me but had to keep taking them. Up next was clinical studies for Praluent. Never knew for sure that I was on it. Today, 1 year after it was officially on the market, my cholesterol was 149!!!! Lowest in 34 years, from a high of 600! I will take any mild side effects!! I also get help with copay from PAN and worry their help will run out. Thank you God!!"

• Mike...
• July 14, 2016

For High Cholesterol "I couldn't tolerate statins. Tried 3. Each one gave a lot of pain....liver and angina. I had to stop them. While off them for a month my Total Cholesterol went from 165 to 213, LDL's went from 65 to 110. Now my Total is 97 and LDL's are 24. I take Lovaza to keep my HDL's up at 45-49; they never were above 34 my whole life no matter what I tried. I have no side effects and I feel the best in 5 years."

• Emily
• Taken for 1 to 6 months
• June 20, 2023

For High Cholesterol, Familial Heterozygous "I have been taking 150 mg of Praluent for 2 - 3 months and began experiencing thigh pain and weakness, worsening dizziness, and worsening neck, and right knee pain. I used to walk 3 miles a day, do cardio twice a week, weights twice a week. Now my dizziness and leg weakness does not allow me to walk without holding on to the wall or using a cane. My last injection was three weeks ago but symptoms persist though not worsening. Pending Neurology and all the usual workup but I feel strongly it’s Praluent, especially after reading these reviews. Like many others here, I cannot tolerate the statins. Was on Praluent 75mg for about a year and did experience dizziness and thigh “heaviness” and muscle cramping but not to this extent."

• Macem...
• November 19, 2016

For High Cholesterol "After having a myocardial infarction on December 22, 2015 , I was still struggling to get my numbers down, after trying just about every statin on the market, they all made my body ache and my joints so stiff I had to have help getting out of bed. I changed physicians she tried another statin with no luck. She asked if I would be willing to try praluent injections. LONG STORY SHORT NOTICE SIDE EFFECTS NUMBERS HAVE DROPPED DRAMATICALLY AND I FEEL GREAT,only benefit on injections 3 months!!!!!! Thank God for this medication!!!!!!! Got help paying for this from the manufacturer!!!"

• Paul
• Taken for 5 to 10 years
• March 15, 2023

For High Cholesterol "My family has a genetic history of high cholesterol. I've been using Praluent since it came out after the clinical trials. We arranged a cath lab examination two years after I started taking the Praluent, and everything looked normal around the heart, with no calcium buildup other than one little speck. I've never had a stroke or heart attack. My cholesterol levels are in the normal range but were high when I was younger. Statins had too many side effects, and I stopped using them. The side effects are minimal to date. I take two injections twice a month, 150 mg. each."

• CLano
• Taken for 1 to 2 years
• February 8, 2020

For High Cholesterol "I have been on Praluent for about 2 years. My lab numbers are awesome. However, 2 weeks ago after my bimonthly injection I developed a terrible itchy scaly rash at the injection site. No problems with the next 2, but then same thing again (different site). Not sure what's changed."

• dave
• Taken for 1 to 6 months
• June 15, 2024

For High Cholesterol "Very pleased with the rapid cholesterol drop I've experienced in two months taking. But I am a little concerned with muscle aches which I believe started soon after I started it. I feel it is worth the tradeoff, if indeed, this is the case. Also, I have been napping more and feeling more tired since starting but do not see tiredness as a side effect anywhere listed, so it could be coincidental. I had trouble injecting it into my mid-section area because of the awkward angle, I found. So, my doctor recommended my upper thigh. I will try this next time."

• Ssbelts
• Taken for less than 1 month
• June 8, 2023

For High Cholesterol "I have had a CV event and have very high LDL and high LPa and cannot tolerate statins. I started on Praluent and was fine right after the injection. But the first night I woke up with a very swollen tongue and lips and an extremely dry mouth and throat. Took 1/2 Benadryl which seemed to resolve. But over the next few days, I would experience bouts of extremely high BP and flushing of my face and chest (I tend to have low BP so this was very odd). High BP and flushing seemed to occur after any exertion and followed by extreme tiredness for a few weeks and my doctor told me not to take the next dose. Additionally, I have had very unusual headaches, and odd bruising, as well as pinpoint bleeding under my skin and bleeding (large thick clots of blood) from my nose. If I got bit by an insect I would have rubbery clots of blood on my skin. All very strange, and I will be glad when this med has worked its way out of my system (about 40 days). FYI I do have a lot of sensitivity to many meds so I am not surprised."

• Gary...
• Taken for 5 to 10 years
• December 14, 2020

For High Cholesterol, Familial Heterozygous "I'm a 71 yo caucasian male with a diagnosis of PAD, atherosclerosis and hyperlipidemia. I can't tolerate statins due to severe muscle cramping and prescribed Praluent soon after it was approved by the FDA. Aside from minor leg cramping which is controlled by ingesting a banana a day and a runny nose for 24-48 hours after injection, my total cholesterol has dropped from 300+ to less than 100 ! I'm VERY pleased with its' results !"

• Ellie
• Taken for 1 to 6 months
• May 13, 2023

For High Cholesterol "I found Praluent fairly easy to use however I experienced very little reduction in my levels. What I did experience was inflammation of two pre-existing weaknesses in my body - both my feet, and my right elbow. Neither of these things caused me great discomfort prior to Praluent but left me almost unable to walk and performing normal activities with my right arm was excruciatingly painful. I could no longer safely lift things like a kettle, or whipper snip, trim hedges, etc. - things I’d always easily managed. It took me a few weeks to connect the onset of this pain with Praluent but it reduced considerably after I stopped using the product. I will always have these weaknesses in my body but the inflammation caused by this medication is not something I am prepared to put up with for the rest of my life."

• mk3509
• Taken for 1 to 6 months
• October 14, 2018

For High Cholesterol "I've been taking Praluent 75 for 2 months now and report no side effects. I take ibupropen before the injection so I don't feel the small bee sting feeling in my leg. I am 70 yrs old and hope to take the injection forever to prevent another heart attack and a $55,000 bill for 2 days in the hospital. 10-10-2018. Express Scripts just sent me a letter approving my prescription."

• Hazel
• Taken for 1 to 6 months
• September 23, 2020

For High Cholesterol, Familial Heterozygous "Took Repatha for over a year had minor side effects (runny nose only) which eventually disappeared then my insurance changed formularies and had to switch to Praluent not at all happy. Have been taking for two months side effects include constant runny nose fatigue bruising muscle pain and pain and itching at injection site. Would not recommend this medication Repatha in my opinion is much better unfortunately for myself insurance will absolutely not cover Repatha."

• GEB
• Taken for 6 months to 1 year
• August 3, 2023

For High Cholesterol "Fatigue, lethargy, developed varicose veins in both inner thighs best described as parallel mirror twins. The breaks were discovered during a routine annual screening by my surgeon. The tears were serious. My doctor was concerned because previous procedures on legs were minor. My cholesterol was reduced by one hundred points. My memory improved... recall... somewhat. The medicine is brutal and fatiguing. Didn't realize how draining it was until it was interrupted. My energy returned. My dosage was 150 ml injection twice monthly."

• Sandy
• Taken for 2 to 5 years
• April 9, 2024

For High Cholesterol "I've used this medication for two years, and it has significantly reduced my LDL level. This is important because I'm unable to use or tolerate other high cholesterol medications due to adverse effects or lack of effect on the LDL level. My dose is 75 mg given by injection every two weeks, and I give myself the injection at home. My main issue with it is that it is expensive, and it's been a struggle getting it approved by insurances."

• Anonymous
• Taken for 1 to 6 months
• February 12, 2021

For Cardiovascular Risk Reduction "I have been on Praulent for one month and love the results. My LDL is down to 36! I have no side effects except a runny nose. My problem is that it is very difficult to press the injector. I need my husband to press it with all his might. Does anyone have that problem?"

• Gmum
• Taken for 6 months to 1 year
• November 6, 2023

For High Cholesterol, Familial Heterozygous "Having a genetically bad lipid profile, I've tried every oral statin, all giving me debilitating side effects. Zetia is minimally effective. Being on 150 mg Praluent (injection) every 2 weeks for several months, my lipid profile is completely normal for the first time in my adult life. There have been no side effects as well. It is easily injected with no discomfort."

• Mike...
• Taken for 2 to 5 years
• October 5, 2020

For High Cholesterol "After having a heart attack 2 years ago my cardio doctor put me on Praluent painless injections every two weeks in my legs along with daily 20 mg Atorvastatin (Lipitor). Together they both have lowered my bad LDL from 250 down to 25. I'm a 73 year old man. I'm very happy with the results. I don't notice any side effects. I'm also happy my Mutual of Omaha drug plan Plus which covers most of the cost 2020/2021. I'm waiting for the FDA to approve Inclisiran twice a year injections which will be much more cheaper."

• JK_UK
• Taken for 1 to 6 months
• April 15, 2017

For High Cholesterol "46 year old UK male; slim, above average fitness, eats well. Tried 3 different statins with same intolerable brain fog, muscle pains and palpitations over a 3 year period. 1st injection: mild muscle pains in my back, cold legs and feet, morning glory, a little brain fog, looser stools. 2nd injection: similar effects to the 1st but 50% less strong, except the morning glory and looser stools. 3rd injection: mild brain fog for an hour (starting about 2 hours after taking), cold feet, looser stools still. Not had bloods tested yet, but if LDL comes down I'd be very happy to stay on Praluent based on these minor side effects. Very hopeful about this convenient statin alternative."

• JRC
• Taken for 5 to 10 years
• April 5, 2024

For High Cholesterol "I am male, 65 years old, in good shape, fairly active (just had a great stress test), and have survived for 15 years since an emergency quadruple bypass. I have been using Praluent for five years or more at the suggestion of my cardiologist (150mg/mL injection twice a month). It was prescribed because all other medications (mostly various statins) had little to no effect on my cholesterol levels, something all my family members struggle with (however, I am the only one with any heart issues - lucky me). Honestly, and I do feel really bad for the folks who report negative outcomes and symptoms here, but it nearly immediately made a huge difference in my total cholesterol, HDL/LDL, and triglyceride levels, which are stellar then and now. I can also honestly say that I have had absolutely no side effects even though I was prone to some bad ones when on various statins (muscle pain, headaches, etc.). I don't even mind the injectable application as it is a minor inconvenience."

• MtGra...
• Taken for 1 to 2 years
• May 21, 2018

For High Cholesterol, Familial Heterozygous "I used this drug for over a year with good results for my cholesterol, but then developed an allergic reaction to it. The first time it occurred it was bad, but I mistook it for indigestion. The following dose there was no doubt. A few hours after taking the shot I became very nauseous. Had diarrhea, reflux vomiting and bad pain in my stomach and pancreas. Did not take it again."

• Anonymous
• Taken for less than 1 month
• April 1, 2023

For High Cholesterol "I cannot take statins because of the pain they cause in my joints so I gave this a try. I am a female aged 65 yo and I had a heart attack 3 years ago. I have one stent but have other calcified vessels and my cholesterol is high so don’t have a lot of options I’m told by my Cardiologist. I had the worst reaction I’ve ever had to any medication after injecting 75mg of Praluent. Firstly I had a nosebleed and then I had extreme nausea and was throwing up most of the night. I also had a migraine headache that started behind my right eye and lasted for a few days (for which Tylenol 1000mg didn’t help at all!) My BP also went up to 188/100! It has been 11 days since I took that shot and today I have extreme lower back pain as well as lingering dizziness and nausea. I’m supposed to take the second shot 3 days from now. I emailed my Cardiologist with this information but he thinks that’s unusual and that I should go ahead with it."

• Happy...
• Taken for 2 to 5 years
• February 1, 2021

For High Cholesterol "I'm a 73 year old man and I've been doing the 75mg Praluent injections now for almost 4 years with no side effects. My LDL that I get tested every 6 months is is a very low 24 thanks to Praluent. When I had my heart attack 5 years ago my LDL was a very high 250. I'm happy that my CVS Silverscript Plus pays for most of the cost. I also take 20 mg Atorvastatin daily. The painless Praluent auto injector takes about 5 seconds to inject after warming it up and pushing the auto injector button. The only thing I don't like is the high cost and having to keep the Praluent refrigerated before use. For me there is no pain or bleeding at the injection site which is my leg."