Praluent User Reviews & Ratings (Page 4)

• HAP...
• Taken for 5 to 10 years
• December 14, 2023

For High Cholesterol "Been taking since it was experimental, over 5 years now with NO side effects before taking bad cholesterol was near 300 after the test it was around 50. I do and have recommended this medicine, it is a very GREAT med!"

• Emi...
• Taken for 1 to 6 months
• June 20, 2023

For High Cholesterol, Familial Heterozygous "I have been taking 150 mg of Praluent for 2-3 months and began experiencing thigh pain and weakness, worsening dizziness, and worsening neck and right knee pain. I used to walk 3 miles a day, do cardio twice a week, and weights twice a week. Now my dizziness and leg weakness do not allow me to walk without holding on to the wall or using a cane. My last injection was three weeks ago, but symptoms persist, though not worsening. Pending neurology and all the usual workup, but I feel strongly it’s Praluent, especially after reading these reviews. Like many others here, I cannot tolerate the statins. I was on Praluent 75 mg for about a year and did experience dizziness and thigh “heaviness” and muscle cramping, but not to this extent."

• Gai...
• January 25, 2020

For High Cholesterol "I just got approved to use Praluent. I've had it for 4 days now. I'm too nervous to do the injection. So I've been reading all the comments that are helpful. The question I'm looking for, does anyone know the size of the needle, please, as I'm horrified of all needles, please???"

• Anonymous
• Taken for 1 to 6 months
• February 12, 2021

For Cardiovascular Risk Reduction "I have been on Praluent for one month and love the results. My LDL is down to 36! I have no side effects except a runny nose. My problem is that it is very difficult to press the injector. I need my husband to press it with all his might. Does anyone have that problem?"

• Pet...
• February 1, 2020

For High Cholesterol, Familial Heterozygous "I’m a 55-yr-old male with familial hypercholesterolemia. I take Zocor, Crestor, and Praluent. My numbers are awesome. HDL, LDL, all fantastic. I’d been on Praluent for about 6 months, so about 12 doses of 150 mg. I have developed several muscle and joint pains in my hips that are now spreading into my legs. I have also developed mild neuropathy in my hands. I am an avid golfer and tennis player, and it is now to the point where I have had to stop playing both and ache when I walk. I am considering going off the Praluent and just accepting my fate!!!"

• Doo...
• Taken for less than 1 month
• August 4, 2019

For High Cholesterol "I have only been taking this medication, Praluent, a short time, so I can't say whether it has helped reduce my cholesterol. What I don't like about this drug is that it makes me feel nauseous, and I sweat profusely, which is upsetting and embarrassing as I work part-time at a store as a dressing room attendant or a cashier."

• Mea...
• October 11, 2018

For High Cholesterol "I have had two shots getting ready for my third. Not sure if I want to take it because I've had chills, headache, nausea a lot, also aching. I'm going to get my blood test tomorrow to see if it's lowered enough for me to keep taking this, 'cause the side effects for me are horrible. Also, my blood pressure goes from being high to drastically low."

• EdE...
• Taken for 1 to 6 months
• June 6, 2018

For High Cholesterol "My total cholesterol has dropped from 268 to 125! The 'all-important' LDL (bad cholesterol) has been reduced from 184 to 50! Dramatic reductions in just 6 weeks on 150 mg every two weeks. My HbA1c is essentially the same at 6.6 (was 6.7)...not bad. Kidney, liver- all stable and okay. No side effects at all with Praluent. Statins are toxic to my system-not just side effects, but toxic."

• mic...
• Taken for 2 to 5 years
• May 12, 2020

For High Cholesterol "I started on Praluent 3 years ago, not long after it was first introduced in the UK. After over ten years of on and off, mostly off statins, due to their almost crippling side effects, this drug has been a godsend. My cholesterol is below recommended levels for the first time ever, for two years in a row. After having stents and one heart attack, I now feel, for the first time in years, I'm no longer waiting for another imminent episode! Side effects: a few muscle aches, but nothing like the statins, and only last a short while. Easy to take once every two weeks."

• jun...
• Taken for 2 to 5 years
• June 23, 2024

For High Cholesterol "I have stopped taking injections which were every 2 weeks. I have itching all over, tingling all over, mouth ulcers, walking problems, pains in legs. I am passing urine more often. I have stopped only 4 days ago. I told the doctor who gave this to me, and he said to stop taking it and see what happens. I have to have a second blood test (full one) next week as the first one was incorrect or had queries. I have been taking this medication for approximately 2 years now. Although it brought my cholesterol right down, I feel I can control it with diet as it's not worth the effects I am having. I have read it takes up to 100 days for it to clear the system."

• Anonymous
• Taken for less than 1 month
• June 8, 2023

For High Cholesterol "I took the first Praluent 150 injection, and on the 3rd day after, I got a terrible UTI. On day 5, I got severe body aches and muscle spasms. I’m on my second antibiotic for the UTI. I went to the doctor once and, 5 days later, ended up at the ER. I’m supposed to take my 2nd injection on Saturday, but that won’t be happening. I’m just hoping my body gets back to normal soon. The Praluent injection was worse than Crestor or Lipitor for me."

• Mar...
• Taken for 2 to 5 years
• April 18, 2023

For Cardiovascular Risk Reduction "I have been taking Praluent injections for 2 years. I started with 75 mg for one year and a half, every other week. Then the doctor increased it six months ago to 150 mg, every other week. I have had hair loss for two years and bald spots on my scalp. I am a licensed cosmetologist for 40 years, and I know what alopecia is. They keep telling me it’s not the Praluent. I do feel it is, and I’ve had a lot of stomach distress. How do I decipher if this is causing my hair loss when the doctor's office says it's not?"

• Mik...
• July 14, 2016

For High Cholesterol "I couldn't tolerate statins. Tried 3. Each one gave a lot of pain... liver and angina. I had to stop them. While off them for a month, my total cholesterol went from 165 to 213, LDLs went from 65 to 110. Now my total is 97 and LDLs are 24. I take Lovaza to keep my HDLs up at 45-49; they never were above 34 my whole life, no matter what I tried. I have no side effects and I feel the best in 5 years."

• Cro...
• Taken for less than 1 month
• December 23, 2020

For High Cholesterol "Switched from Repatha to Praluent due to insurance. I injected the first of the month. Now, after 2 ER visits and a bunch of prednisone, it's finally starting to leave my body. To recap, the next day I felt like I got hit with the flu, had no energy, and felt like crap. Shortly after, my whole face, fingers, and feet blew up, and I was covered in hives from head to toe. I'm a day done with my steroids, and the hives are already coming back. Not as bad, but enough to be bothersome, especially during bedtime. If you have any sensitivity to statins, I highly suggest you stay away."

• don...
• Taken for 1 to 6 months
• November 3, 2024

For High Cholesterol "Been taking shots for 4 months. My eyes are very red, so I bought eye drops, did not help. Have back pain and upper thigh pain and itching. It lowered everything, but I can't take the tiredness anymore. I want to sleep all the time. This stuff is evil. Now I have to wait 100 days to get it out of my system."

• deb...
• Taken for 1 to 2 years
• December 12, 2022

For High Cholesterol, Familial Heterozygous "It is now some time since I gave feedback on Praluent. I became extremely ill and discontinued it off my own bat because we were under lockdown and could get any help. Although the episodes finished, I am, nevertheless, still struggling with the effects and am beginning to believe that I shall never go back to who I was before Praluent. The consultant, reluctantly, admitted that there were 'issues' with the product, but I don't see that it has been taken off the market. Where can I go for help? Do we put up with being treated like guinea pigs and then abandoned when things go wrong?"

• Lon...
• Taken for 1 to 6 months
• July 20, 2018

For High Cholesterol "After 15 years on statins, I could not accept living with the continuous aches and pains. After three months on Praluent, I feel fine, no noticeable side effects, no problem with injections. Cholesterol numbers reduced dramatically."

• Coa...
• Taken for 6 months to 1 year
• September 1, 2020

For High Cholesterol, Familial Heterozygous "I was prescribed Repatha, however, my insurance forced me to take Praluent. I started on Praluent just after Christmas 2019 and continued every 2-weekly shots through August 2020. My body will not tolerate statin drugs, so this was my only option to try and control my cholesterol. In December of 2019, my total cholesterol was 286, after 8 months of using Praluent, my cholesterol only went down by 2 points to 284. My triglycerides went up by 50 points, 108 in December to 158 in August. HDL (good cholesterol) went down by 3 points, 50 in December to 47 in August. Finally, my LDL went down by 9 points, 214 in December to 205 in August. In summation, Praluent did not work for me. Hopefully, I have better results on Repatha. From a side effect point of view, I would take the injection on a Thursday, and by Saturday afternoon I would be bothered with a headache. Usually, by Sunday night, the headache would resolve, I would be fine until my next dose."

• Mac...
• November 19, 2016

For High Cholesterol "After having a myocardial infarction on December 22, 2015, I was still struggling to get my numbers down. After trying just about every statin on the market, they all made my body ache and my joints so stiff I had to have help getting out of bed. I changed physicians, she tried another statin with no luck. She asked if I would be willing to try Praluent injections. Long story short, notice side effects, numbers have dropped dramatically, and I feel great, only benefit on injections three months. Thank God for this medication! Got help paying for this from the manufacturer!"

• uni...
• Taken for less than 1 month
• April 29, 2020

For High Cholesterol "Mine is the usual story. I got horrific muscle cramps, especially in my thighs, from taking even the smallest imaginable dose of a statin (5 mg per week). I just had to stop taking any statin. I tried diet alone to lower my numbers, and that didn't work. I fought trying an injectable for my cholesterol/cardiovascular issues for several years until I didn't have any options left. Two weeks ago, I gave myself my first Praluent injection. I'm needle-phobic, so imagine my surprise when I never even felt the tiny needle and had to check to make sure it was actually in my skin. Then yesterday, I did my second of my two monthly injections, and it was the same; over in about 5-10 seconds! This was the big hurdle for me, so if you think you can't do an injectable, try it. It's really no big deal. This drug costs me $250/month with my Blue Cross insurance. I am hoping as users go up, the price will go down. Time will tell if my cholesterol goes down."

• Sta...
• Taken for 6 months to 1 year
• April 29, 2019

For High Cholesterol, Familial Heterozygous "61 y.o. female with FH (familial high cholesterol): I had pre-existing neuralgia, which was somewhat manageable. I tried statins, and they brought my pain levels to 10+, so no statins for me. Praluent was okay regarding neuralgia for the first few months when I was yanking out the needle at the halfway point (due to a bad reaction to Repatha in 2018...another story for another day). 8 weeks ago, when I started leaving the needle in until it retracted, i.e., giving myself the full 75 mg, that's when my neuralgia started to break through intensely. Very disappointing. I hope that, going back to the half dose, even though it's very hard to estimate when to pull out the needle -- the needle is so fast, I hope to reverse the increased neuralgia. I need a full dose, but it looks like I can't tolerate it. Dang! When the nerve pain increases, my good mood disappears."

• CLa...
• Taken for 1 to 2 years
• February 8, 2020

For High Cholesterol "I have been on Praluent for about 2 years. My lab numbers are awesome. However, 2 weeks ago, after my bimonthly injection, I developed a terrible itchy, scaly rash at the injection site. No problems with the next 2, but then same thing again (different site). Not sure what's changed."

• zig...
• Taken for 1 to 2 years
• November 1, 2016

For High Cholesterol, Familial Heterozygous "35-year history here of familial high cholesterol. Participated in medical studies many of these years-first for new statins, then other drugs. Lowest my overall cholesterol went was 259, that with max dose of Crestor and Zetia combined. Took that before and after triple bypass and stent on the 4th artery. Eventually, all statins cause too much musculoskeletal pain for me, but had to keep taking them. Up next was clinical studies for Praluent. Never knew for sure that I was on it. Today, 1 year after it was officially on the market, my cholesterol was 149!!!! Lowest in 34 years, from a high of 600! I will take any mild side effects!! I also get help with copay from PAN and worry their help will run out. Thank you, God!!"

• DG ...
• Taken for 1 to 6 months
• July 16, 2024

For High Cholesterol "Allergic to statins. Severe thigh cramping with all of them. Unbearable. Tried Praluent with nearly immediate results. Cholesterol went from very high to perfectly normal after only one or two injections. No side effects. Downside was that price became prohibitive after a few refills."

• Dia...
• Taken for 1 to 2 years
• April 11, 2024

For High Cholesterol "I’ve been on Praluent for over 2 years and have not had any side effects. I take the injection every 2 weeks, and all cholesterol levels are very good. If I had read all of these negative comments before using this medicine, I would’ve been petrified to try it."