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Acetaminophen / hydrocodone for Pain User Reviews (Page 5)

Brand names: Xodol Zyfrel

Acetaminophen / hydrocodone has an average rating of 6.2 out of 10 from a total of 708 reviews for the treatment of Pain. 52% of reviewers reported a positive experience, while 31% reported a negative experience.

Reviews for Acetaminophen / hydrocodone

  • Take...
  • Taken for 1 to 6 months
  • September 23, 2021

Norco (acetaminophen / hydrocodone) "These Generic pain medications are horrible. Many times they have NO MANUFACTURE name on them. I am being given one now that gives me vertigo every single day, all day long. I loose my balance, have severe headaches, nauseated and blurry vision. These side effects have me bed ridden now. I am drowsy and sleep ALOT. There was a note on my account with the pharmacy to not give this brand to me, but NOW I am being told, " YOU GET WHAT WE HAVE" I was willing to pay out of pocket for name brand, I was told " NO ONE STOCKS NAME BRAND ANY MORE. I went to every pharmacy in our area and called ones that were not so close. I now don't have the energy to move and take care of many things. If I don't take them, I am in too much pain. Just as bad is the attitudes of the pharmacist now thinking it's open season on people who need these medications. They talk over me , they talk down to me and everyone ignores me and act like I am not a person"

3 / 10
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33 Report
  • shamy...
  • Taken for 1 to 2 years
  • March 13, 2014

Norco (acetaminophen / hydrocodone) "Been taking Norco for 19 months as I have neuropathic foot, leg, hip, low back pain. Trying not to have back fusion. Norco 5mg/325mg does great for pain control. Without this, I would be flat on my back in bed. Thank goodness for Norco."

10 / 10
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87 Report
  • mikel
  • Taken for less than 1 month
  • November 4, 2020

Norco (acetaminophen / hydrocodone) "I have extreme pain from a tooth and my dentist prescribed me Norco and I thought the excruciating pain will finally end. This stuff is complete garbage. I usually have to take lower doses due to sensitivity and this was a full dose. It did absolutely nothing for pain. The only thing it did was make me a tiny bit tired, but Tris needs to figure out what they are doing. DO NOT use this for pain relief, ibuprofen does a lot better."

1 / 10
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40 Report
  • Anony...
  • Taken for 1 to 6 months
  • September 8, 2021

Lortab (acetaminophen / hydrocodone) "This particular brand with the label G 037 is the WORST brand of hydrocodone I’ve ever had in my life! No pain relief at all, as if I was taking a placebo pill.. how can you sell this to folks in pain??"

1 / 10
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33 Report
  • ghani
  • Taken for less than 1 month
  • January 26, 2014

Norco (acetaminophen / hydrocodone) "Taking this for a very painful dental abscess. It's been a Godsend. Got my first significant bit of sleep in days. It does give me dry mouth, so if you take it for dental reasons, Biotene mouthwash is helpful."

9 / 10
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87 Report

Are you taking this medicine?

  • Dog...
  • October 24, 2019

"I have taken Watson brand hydrocodone and acetaminophen off and on for many years. Watson brand works great but they are no longer making the drug. CVS is buying the worst generics available outside the country. Now they only have Aurobindo brand and it does not work at all!! There are many articles online about constant quality problems with Aurobindo. Why doesn't the FDA do something? Why does CVS buy drugs from Aurobindo, knowing there is constant quality control problems? EVERYONE MUST REPORT THESE BAD DRUGS OR THE FDA CAN'T DO ANYTHING!!! WWW.FDA.GOV/MEDWATCH CLICK ON RED BUTTON FOR REPORT A PROBLEM"

1 / 10
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48 Report
  • Sannda
  • Taken for 10 years or more
  • September 28, 2022

"I have tried every generic pill of this medication. Can't take any of them. I use to always use Watson which was excellent. But, Watson went out of business. The generics now available make me extremely sick. The sickness lasts into the next day after taking just 1 generic pill. Found no relief from the pain. But...I just come across one Hydrocodone/Acetaminophen that I CAN handle. It is made by Rhodes. Well worth your time to look into this heaven-sent medication/"

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  • HELP...
  • Taken for 10 years or more
  • September 24, 2021

"I knew I wasn't imagining things. Like so many others, a half to 2 a day gave used to give e some quality of life. One can take 3 of these within 2 hours and just end up going to bed. OUR PAIN IS REAL and no one either cares or listens! The government tries to punish the doctors, which in turn, punishes those of us in severe pain 24/7. This may seem heartless but I don't care anymore, we use our medicine legitimately & have been thrown aside to save the addicts! That's wrong!! All this did was turn them onto heroin and fentanyl. So, you've created a new problem of needle users and still dealing with OD's. You have responsible adults suffering and taking more meds than one should, just trying to keep from committing suicide from the horrible pain! I doubt any lawyer is going to risk having the watchdogs following them just to help us. All I do is cry and pray for a solution, either by someone finally hearing us or God taking me away from this. Prayers, blessings whatever your belief is!"

2 / 10
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32 Report
  • AJano
  • Taken for less than 1 month
  • January 23, 2020

Norco (acetaminophen / hydrocodone) "Was prescribed this to help manage the insane pain of a kidney stone and it seems to do pretty much nothing. I don’t take any other opiates but I have to imagine that they work better than this. I get virtually no relief at all."

2 / 10
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45 Report
  • Paul
  • Taken for 6 months to 1 year
  • February 16, 2020

"Yes I have felt that there is a difference now in the effectiveness of Watson brand of acetaminophen with hydrocodone 10/325. Now I know I am not crazy. The 5/500 Vicodin back in the 90's worked better than today's 10/325 Watson. Even when I took 10/ 325 Watson's in 2008 they worked better. I personally thought something was up three years ago and it started then. The problem is I don't have any pills from that era 90's or mid 2000's to test and compare the difference with a lab breaking down the chemicals."

4 / 10
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  • Abriton
  • Taken for 2 to 5 years
  • September 6, 2019

"PS to my previous comments, 2019-08-28, 2019-08-26. It seems from reading the 2019 reviews here, that this started this year. I agree. You will see from my previous comments in this page that Mallinckrodt told my pharmacy that they had outsourced their hydrocodone. This may be the reason. The other thing that happened was, I used to pay $20 for 30. Last month they charged me $8! I assume Mallinckrodt offered financial incentives! Please, everyone complain to the FDA, to Mallinckrodt headquarters and your pharmacy if you are having issues with your acetaminophen/hydrocodone. Call round other pharmacies and ask what brand they use. I did, and found a small, local pharmacy that had Par. I will go there. You can ask your doctor for a paper prescription so you can take it where you like. That is what I do."

1 / 10
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47 Report
  • OC Guy
  • May 23, 2016

Norco (acetaminophen / hydrocodone) "I tore my adductor muscles from slipping on some mats in a martial arts class 6 years ago. I've had two sports hernia operations which helped but I have some permanent nerve damage in my thighs. I get burning and shocks in my thighs. I have been taking 1-2 norco as needed for several years and they work great. I know they are highly addictive but no other pain killer allows me to work, have fun with family and friends, and continue to train in my martial arts. I sometimes go 3-5 days without any and rarely take more than 2 a day. If you have chronic pain or permanent nerve damage these can give you your life back."

8 / 10
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69 Report
  • Pyt
  • Taken for 2 to 5 years
  • November 15, 2019

"I have taken the acetaminophen with hydrocodone Watson brand 10/325 and now take M367 which is another manufacturing company. I haven’t noticed too much of a difference. My friend who also suffers with pain takes acetaminophen with hydrocodone imprinted 358 made by lupin. She hates them. I never realized that manufacturing companies did this sort of thing. It’s sad for the people who suffer so greatly."

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45 Report
  • Retired...
  • October 15, 2016

Norco (acetaminophen / hydrocodone) "When they switched me to Norco I had to deal with more pain. The medication is half as effective and makes me sick to my stomach many times. GOV'T doesn't care about the people with real pain more concerned with the drug addicts (which more people are becoming because they can't get the pain relief they need.)"

1 / 10
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66 Report
  • Deedy
  • February 7, 2020

"I've been on on Norco generic (acetaminophen with hydrocodone) 7.5 manufacturer Lupin but now they have changed manufacturer and it is not helping me. Mallinckrodt. I take these and I go to sleep with a little relief but then wake up with pain . The manufacturer LUPIN worked for me but now I can't find a pharmacy who carries them. What has happened?"

10 / 10
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43 Report
  • Missy
  • Taken for 1 to 6 months
  • September 8, 2018

"Since the "druggies" decided to ruin it for all who actually need an opiate, we're pretty have a problem (Sudafed as well)! I used to take Lortab 10 (Pink). My doctor switched me to Norco 7.5/325, and Man 'ole Man - JUNK! I think the Watsons are the best, and will only fill if I see an imprint of N357 or 3203-Watson! The M366 (Mallinckrodt Pharmaceuticals) are worthless, and I will NOT fill if that's all they have! My script is now 6 days past due, because I'm looking for a pharmacy who doesn't carry that rubbish brand! I take 3, and I still can't move! An Advil works better than those! We shouldn't have to live in pain because SOME people WANT to abuse their meds! I do not, and I'm randomly tested! NEVER failed, so why are we being punished?! We shouldn't be punished, THEY should! This is getting ridiculous! "

1 / 10
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52 Report
  • GRGuy
  • Taken for 10 years or more
  • October 13, 2019

"Unfortunately, I’ve been on various hydrocodone/apap (acetominophen) combinations since 2001 for chronic pain caused by a gunshot that caused irreparable damage. For about the last 4 years I’ve been prescribed Norco 10/325. All was well until around the end of 2017. My regular pharmacy began carrying a different generic than the previous Watson brand I was receiving. Prior to this, I did have a few occasions where I did receive a different brand than Watson but never noticed any difference in quality (prior to 2014). Since Watson is long gone, I’ve tried probably 4 different generics & they are total garbage. They either had no effect, or too many negative side effects (heavy sedation, nausea, overall lousy feeling, etc). Luckily, my doctor and pharmacist are knowledgeable and do not believe in the “generics are the exact same” philosophy. My doctor recently put me on Nalocet (name brand, made in USA & held to higher standards) & my pain has been properly brought back under control."

4 / 10
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44 Report
  • DeAnna...
  • Taken for 2 to 5 years
  • April 11, 2013

Norco (acetaminophen / hydrocodone) "This medication is prescribed 10/350 mg up to 4 times per day - or as needed. I normally take it 3 times per day. It is the only medication that has not caused stomach bleeding problems as aspirin did; has not caused liver damage as Tylenol did; and has not caused kidney necrosis/nephritis as Advil did."

10 / 10
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  • Jacquie
  • Taken for 2 to 5 years
  • June 10, 2019

"The prescription for Hydrocodone 10/325 I got this month from my usual pharmacist was manufactured by Aurobindo, an India company. Recently I saw a documentary on ineffective pharmaceuticals that come from foreign countries and it concerns me considering how expensive they are. I use CVS for my monthly prescriptions. Norco is getting hard to get for chronic pain patients like myself because the DEA is watching it carefully to make sure it isn't causing addiction. It is pretty much all I get any more after two decades of chronic pain. I am going to complain to my pharmacist that this Aurobindo drug is ineffective and very expensive. I am prescribed 3 a day and if I take 3 a day I am still in pain and end up taking more with little relief. I am not a drug addict. I have serious bone issues that require more than Ibuprofen and Gabapentin. I am very concerned about the generic drugs we are given through legal processes."

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  • Momof
  • Taken for less than 1 month
  • October 14, 2018

"I have been using hydrocodone for 10 years for multiple problems I have, hormone imbalance that causes migraines, back pain, ulcerative colitis, etc. I do not take them regularly, but as needed, and only get my prescription filled for them twice a year. The couple times a month I need them, I REALLY need them to function through the pain. This new brand Walgreens has switched to is terrible! I took one for back pain, and the following day I had a migraine that grew worse as the day went on. I can only guess the fillers in this brand are something my body is rejecting. On top of that, it did not remove the pain in my back. Not only did it not take the back pain away, it caused me days worth of pain to follow in a multi day migraine. This whole bottle is a waste, I will never put another one of these in my mouth again. The pills are marked G 037 which came up as Tris Pharma Inc. Shame on Walgreens’s for saving a few dollars at the expense of their patients!"

1 / 10
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50 Report
  • SGano
  • Taken for 10 years or more
  • September 3, 2019

"I’ve been on generic norco acetaminophen/hydrocodone 10/325 Watson for many years same dose and amount a day. Anyone gone to a compound pharmacy to recreate the meds that work? Since Teva bought Actavis and discontinued this med I’ve been on Mallinckrodt and Ameal. Mallinckrodt is awful but Ameal (sp?) didn’t work as well as Watson but side effects were far less than Mallinckrodt. Now I’m having nausea, pain, sleeping and normally I didn’t have any side effects from Watson. How, since these meds are supposedly dangerous, are the government driving out safe American made meds overseas meds that are subpar and no quality? We have to suffer and can’t ask for the right quality safe meds."

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44 Report
  • Daxton
  • March 30, 2013

Vicodin (acetaminophen / hydrocodone) "Over the years (I'm 75 now), I have used Vicodin 5/325mg for a range of things: had stable fracture of spine after a fall, broke one shoulder in 3 places, and the other a couple years ago. Have chronic back pain and if it gets bad, I get a prescription for it. A few surgeries: prostate, hernia, gall bladder, several dental procedures/surgeries. In each and every one of the mentioned cases, the Vicodin has been the pain management of choice. It frustrates me that after a doctor prescribed a couple of times, they are reluctant to further prescribe, citing the addiction factor. I've heard that doctors tend to UNDER PRESCRIBE because of this."

9 / 10
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82 Report
  • Anonymous
  • May 20, 2009

Lortab (acetaminophen / hydrocodone) "I take Lortab because I have osteoarthritis of the spine, and I would not be able to conduct my life on a daily basis if not for this medication. Some doctors don't like giving this medicine out to patients because it is habit-forming. But, like I told my doctor, pain 24/7 or a slight addiction. I will take the addiction. I can get over an addiction, but this pain is here to stay and is not going to get any better."

10 / 10
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101 Report
  • lreed...
  • Taken for 10 years or more
  • May 20, 2021

"I have been on Watson brand of acetaminophen/hydrocodone for 12 years for Sjogrens, Fibro, RA, ON. I got a new script switched up from 7.5 mg to 10 mg. tablets. Pharmacy filled it with Mallinckrodt brand and seriously they don't work!! So angry!! What a waste, wondering how I will make it thru the next 30 days"

1 / 10
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31 Report
  • Always...
  • Taken for 5 to 10 years
  • May 9, 2023

Norco (acetaminophen / hydrocodone) "I am a 53-year-old female who has undergone multiple surgeries on both knees and back twice a year, including knee replacements, steroid injections, cortisone injections, and nerve cauterization. I have been taking 10/325 for 7 years and only receive my prescriptions through a hospital or one Walgreens location because other Walgreens carry hydrocodone with a different formulation. Initially, I only had to take half or 1 pill a day at night, but now I have to take it every 6 or 7 hours due to severe sciatica, RLS, and nerve damage from all the surgeries. It's strange that some of my pills work fine and help relieve my pain, but others in the same bottle make me feel like I took three pills and leave me feeling sick and scared like I am overdosing. I have tried taking OTC naproxen for my back and muscle pain, and it helps to some extent. However, I would appreciate it if Norco was consistent across all Walgreens because they look and make me feel different, even having different numbers on them. I did some research and found out that they don't make them anymore, so the pharmacy might be giving out old meds."

7 / 10
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15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.