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Acetaminophen / hydrocodone for Pain User Reviews (Page 5)

Brand names: Xodol Zyfrel

Reviews for Acetaminophen / hydrocodone

Commonly mentioned side effects
  • Tak...
  • Taken for 1 to 6 months
  • September 23, 2021

Acetaminophen / hydrocodone "These generic pain medications are horrible. Many times they have no manufacturer name on them. I am being given one now that gives me vertigo every single day, all day long. I lose my balance, have severe headaches, am nauseated, and have blurry vision. These side effects have me bedridden now. I am drowsy and sleep a lot. There was a note on my account with the pharmacy to not give this brand to me, but now I am being told, 'You get what we have.' I was willing to pay out of pocket for name brand, I was told, 'No one stocks name brand anymore.' I went to every pharmacy in our area and called ones that were not so close. I now don't have the energy to move and take care of many things. If I don't take them, I am in too much pain. Just as bad is the attitudes of the pharmacists now thinking it's open season on people who need these medications. They talk over me, they talk down to me, and everyone ignores me and acts like I am not a person."

3 / 10
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  • Anonymous
  • May 20, 2009

Acetaminophen / hydrocodone "I take Lortab because I have osteoarthritis of the spine, and I would not be able to conduct my life on a daily basis if not for this medication. Some doctors don't like giving this medicine out to patients because it is habit-forming. But, like I told my doctor, pain 24/7 or a slight addiction. I will take the addiction. I can get over an addiction, but this pain is here to stay and is not going to get any better."

10 / 10
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  • Pau...
  • Taken for 6 months to 1 year
  • February 16, 2020

"Yes, I have felt that there is a difference now in the effectiveness of Watson brand of acetaminophen with hydrocodone 10/325. Now I know I am not crazy. The 5/500 Vicodin back in the '90s worked better than today's 10/325 Watson. Even when I took 10/325 Watson's in 2008, they worked better. I personally thought something was up three years ago, and it started then. The problem is I don't have any pills from that era, '90s or mid-2000s, to test and compare the difference with a lab breaking down the chemicals."

4 / 10
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  • Bac...
  • December 13, 2018

Acetaminophen / hydrocodone "I found hydrocodone to be more effective than tramadol, gabapentin, then they changed the drug over the years due to drug addicts' abuse. Once the gold standard until people learned how to abuse it. Taken as prescribed, it is effective with little or no side effects. However, it has deadly side effects when abused or mixed with other drugs. It was made with 660 mg of acetaminophen, which is dangerous if taking 10 pills to get high, you could do irreparable damage to your liver. So the amount of acetaminophen was limited to 325 in each pill. Some drug addicts figured out how to crush it up, prompting even more changes in the medication to prevent that abuse. Then some unethical doctors started overprescribing it to people who didn't need it, prompting tighter restrictions by the government. The government has moved it from schedule III to schedule II drug, further limiting its use, while states make marijuana, which is listed as a schedule I drug, legal for recreational use. Stop abuse."

7 / 10
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  • Anonymous
  • March 14, 2020

"10 years of taking these with little problems, and just refilled. I have been bleeding out of my nose, mouth, and urine since getting a new batch of medication. The doctor is too worried about the bleeding, and I am in pain. What is in these pills?"

1 / 10
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  • sha...
  • Taken for 1 to 2 years
  • March 13, 2014

Acetaminophen / hydrocodone "Been taking Norco for 19 months as I have neuropathic foot, leg, hip, low back pain. Trying not to have back fusion. Norco 5mg/325mg does great for pain control. Without this, I would be flat on my back in bed. Thank goodness for Norco."

10 / 10
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  • mik...
  • Taken for less than 1 month
  • November 4, 2020

Acetaminophen / hydrocodone "I have extreme pain from a tooth, and my dentist prescribed me Norco, and I thought the excruciating pain would finally end. This stuff is complete garbage. I usually have to take lower doses due to sensitivity, and this was a full dose. It did absolutely nothing for pain. The only thing it did was make me a tiny bit tired, but Tris needs to figure out what they are doing. DO NOT use this for pain relief, ibuprofen does a lot better."

1 / 10
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  • HEL...
  • Taken for 10 years or more
  • September 24, 2021

"I knew I wasn't imagining things. Like so many others, a half to 2 a day used to give me some quality of life. One can take 3 of these within 2 hours and just end up going to bed. Our pain is real, and no one either cares or listens! The government tries to punish the doctors, which in turn punishes those of us in severe pain 24/7. This may seem heartless, but I don't care anymore, we use our medicine legitimately and have been thrown aside to save the addicts! That's wrong! All this did was turn them onto heroin and fentanyl. So, you've created a new problem of needle users and are still dealing with ODs. You have responsible adults suffering and taking more meds than one should, just trying to keep from committing suicide from the horrible pain! I doubt any lawyer is going to risk having the watchdogs following them just to help us. All I do is cry and pray for a solution, either by someone finally hearing us or God taking me away from this. Prayers, blessings, whatever your belief is!"

2 / 10
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  • GRG...
  • Taken for 10 years or more
  • October 13, 2019

"Unfortunately, I’ve been on various hydrocodone/APAP (acetaminophen) combinations since 2001 for chronic pain caused by a gunshot that caused irreparable damage. For about the last 4 years, I’ve been prescribed Norco 10/325. All was well until around the end of 2017. My regular pharmacy began carrying a different generic than the previous Watson brand I was receiving. Prior to this, I did have a few occasions where I did receive a different brand than Watson but never noticed any difference in quality (prior to 2014). Since Watson is long gone, I’ve tried probably 4 different generics, and they are total garbage. They either had no effect or too many negative side effects (heavy sedation, nausea, overall lousy feeling, etc.). Luckily, my doctor and pharmacist are knowledgeable and do not believe in the “generics are the exact same” philosophy. My doctor recently put me on Nalocet (name brand, made in the USA & held to higher standards), and my pain has been properly brought back under control."

4 / 10
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  • Dee...
  • February 7, 2020

"I've been on Norco, generic (acetaminophen with hydrocodone) 7.5, manufacturer Lupin, but now they have changed manufacturers, and it is not helping me. Mallinckrodt. I take these, and I go to sleep with a little relief, but then wake up with pain. The manufacturer LUPIN worked for me, but now I can't find a pharmacy that carries them. What has happened?"

10 / 10
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  • Dax...
  • March 30, 2013

Acetaminophen / hydrocodone "Over the years (I'm 75 now), I have used Vicodin 5/325mg for a range of things: had stable fracture of spine after a fall, broke one shoulder in 3 places, and the other a couple years ago. Have chronic back pain and if it gets bad, I get a prescription for it. A few surgeries: prostate, hernia, gall bladder, several dental procedures/surgeries. In each and every one of the mentioned cases, the Vicodin has been the pain management of choice. It frustrates me that after a doctor prescribed a couple of times, they are reluctant to further prescribe, citing the addiction factor. I've heard that doctors tend to UNDER PRESCRIBE because of this."

9 / 10
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  • Pyt...
  • Taken for 2 to 5 years
  • November 15, 2019

"I have taken the acetaminophen with hydrocodone Watson brand 10/325 and now take M367, which is another manufacturing company. I haven’t noticed too much of a difference. My friend, who also suffers with pain, takes acetaminophen with hydrocodone imprinted 358 made by Lupin. She hates them. I never realized that manufacturing companies did this sort of thing. It’s sad for the people who suffer so greatly."

3 / 10
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  • Mom...
  • Taken for less than 1 month
  • October 14, 2018

"I have been using hydrocodone for 10 years for multiple problems I have, hormone imbalance that causes migraines, back pain, ulcerative colitis, etc. I do not take them regularly, but as needed, and only get my prescription filled for them twice a year. The couple of times a month I need them, I REALLY need them to function through the pain. This new brand Walgreens has switched to is terrible! I took one for back pain, and the following day I had a migraine that grew worse as the day went on. I can only guess the fillers in this brand are something my body is rejecting. On top of that, it did not remove the pain in my back. Not only did it not take the back pain away, it caused me days' worth of pain to follow in a multi-day migraine. This whole bottle is a waste, I will never put another one of these in my mouth again. The pills are marked G 037, which came up as Tris Pharma Inc. Shame on Walgreens for saving a few dollars at the expense of their patients!"

1 / 10
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  • MeT...
  • Taken for 10 years or more
  • August 7, 2023

"I'm with other people who have complained about the Mallinckrodt brand. It's garbage. I had an allergic reaction to it (I'm on 10/325s). To be fair, I do have a hard time with medications of any kind, and hydrocodone is the only pain medication I can tolerate. I'm on pain management and have to call every pharmacy in town every month to find a different brand, and it's getting worse. The only one I found last month is $236 for my prescription. I have no choice but to pay it again this month."

8 / 10
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  • Jac...
  • Taken for 2 to 5 years
  • June 10, 2019

"The prescription for hydrocodone 10/325 I got this month from my usual pharmacist was manufactured by Aurobindo, an Indian company. Recently, I saw a documentary on ineffective pharmaceuticals that come from foreign countries, and it concerns me considering how expensive they are. I use CVS for my monthly prescriptions. Norco is getting hard to get for chronic pain patients like myself because the DEA is watching it carefully to make sure it isn't causing addiction. It is pretty much all I get anymore after two decades of chronic pain. I am going to complain to my pharmacist that this Aurobindo drug is ineffective and very expensive. I am prescribed 3 a day, and if I take 3 a day, I am still in pain and end up taking more with little relief. I am not a drug addict. I have serious bone issues that require more than ibuprofen and gabapentin. I am very concerned about the generic drugs we are given through legal processes."

3 / 10
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  • AJa...
  • Taken for less than 1 month
  • January 23, 2020

Acetaminophen / hydrocodone "Was prescribed this to help manage the insane pain of a kidney stone, and it seems to do pretty much nothing. I don’t take any other opiates, but I have to imagine that they work better than this. I get virtually no relief at all."

2 / 10
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  • DeA...
  • Taken for 2 to 5 years
  • April 11, 2013

Acetaminophen / hydrocodone "This medication is prescribed 10/350 mg up to 4 times per day - or as needed. I normally take it 3 times per day. It is the only medication that has not caused stomach bleeding problems as aspirin did, has not caused liver damage as Tylenol did, and has not caused kidney necrosis/nephritis as Advil did."

10 / 10
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  • Vic...
  • April 23, 2009

Acetaminophen / hydrocodone "This combination of Hydrocodone/acetaminophen is the best at relieving pain. I have tried Vicodin, Lortab, Lorcet, Vocoprofen, Vicodin HP, and just about every different combination, and Norco works the best by far. It relieves my pain in all parts of my body, and is also great for headaches, terrible back pain, and abdominal cramping. This drug is much less addicting and has fewer episodes of nausea/vomiting."

10 / 10
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  • Ret...
  • October 15, 2016

Acetaminophen / hydrocodone "When they switched me to Norco, I had to deal with more pain. The medication is half as effective and makes me sick to my stomach many times. The government doesn't care about the people with real pain, more concerned with the drug addicts (which more people are becoming because they can't get the pain relief they need.)"

1 / 10
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  • Jak...
  • May 22, 2008

Acetaminophen / hydrocodone "The Norco works great for breakthrough pain. It does not last too long. You can double the effects of this drug if you take Tagamet 30 minutes before and you have an empty stomach. Also, taking Soma with this will increase the strength and will last longer. I guarantee if you try this, you will thank me."

9 / 10
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  • Mis...
  • Taken for 1 to 6 months
  • September 8, 2018

"Since the 'druggies' decided to ruin it for all who actually need an opiate, we're pretty have a problem (Sudafed as well)! I used to take Lortab 10 (Pink). My doctor switched me to Norco 7.5/325, and man 'ole man - junk! I think the Watsons are the best and will only fill if I see an imprint of N357 or 3203-Watson! The M366 (Mallinckrodt Pharmaceuticals) are worthless, and I will NOT fill if that's all they have! My script is now 6 days past due because I'm looking for a pharmacy that doesn't carry that rubbish brand! I take 3, and I still can't move! An Advil works better than those! We shouldn't have to live in pain because SOME people WANT to abuse their meds! I do not, and I'm randomly tested! NEVER failed, so why are we being punished?! We shouldn't be punished, THEY should! This is getting ridiculous!"

1 / 10
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  • Abr...
  • Taken for 2 to 5 years
  • September 6, 2019

"PS to my previous comments, 2019-08-28, 2019-08-26. It seems from reading the 2019 reviews here that this started this year. I agree. You will see from my previous comments on this page that Mallinckrodt told my pharmacy that they had outsourced their hydrocodone. This may be the reason. The other thing that happened was I used to pay $20 for 30. Last month they charged me $8! I assume Mallinckrodt offered financial incentives! Please, everyone complain to the FDA, to Mallinckrodt headquarters, and your pharmacy if you are having issues with your acetaminophen/hydrocodone. Call around to other pharmacies and ask what brand they use. I did, and found a small, local pharmacy that had Par. I will go there. You can ask your doctor for a paper prescription so you can take it where you like. That is what I do."

1 / 10
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  • SGa...
  • Taken for 10 years or more
  • September 3, 2019

"I've been on generic Norco acetaminophen/hydrocodone 10/325 Watson for many years, same dose and amount a day. Anyone gone to a compound pharmacy to recreate the meds that work? Since Teva bought Actavis and discontinued this med, I've been on Mallinckrodt and Ameal. Mallinckrodt is awful, but Ameal (sp?) didn't work as well as Watson, but side effects were far less than Mallinckrodt. Now I'm having nausea, pain, sleeping, and normally I didn't have any side effects from Watson. How, since these meds are supposedly dangerous, are the government driving out safe American-made meds overseas, meds that are subpar and no quality? We have to suffer and can't ask for the right quality safe meds."

5 / 10
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  • ros...
  • March 14, 2008

Acetaminophen / hydrocodone "I have spinal stenosis and have tried the gauntlet of pain relievers. I have found Norco to be one of the best that I have tried. I take one 10/750 every 6-8 hours, and I find it keeps me feeling the best I can with the condition I have."

8 / 10
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  • Hel...
  • Taken for 1 to 2 years
  • September 20, 2022

"You can file a complaint online with the FDA, no longer have to print out and fax. These drug manufacturers need to be fined hugely for making worthless, cheap medications that do not work as well as the brand name, but also can be dangerous and cause many side effects otherwise not found in properly made brand name medication. Here is the link. Takes about 10 minutes all online, submit a complaint, just Google 'MedWatch: The FDA Safety Information and Adverse Event Reporting Program.'"

4 / 10
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24 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.