Citric acid and sodium bicarbonate

Generic name: citric acid and sodium bicarbonate [ SIT-rik-AS-id-and-SOE-dee-um-bye-KAR-bo-nate ]
Brand name: Alka-Seltzer Heartburn Relief Lemon Lime
Dosage form: oral tablet, effervescent (1000 mg-1650 mg)
Drug class: Antacids

Medically reviewed by Drugs.com on Feb 11, 2025. Written by Cerner Multum.

What is citric acid and sodium bicarbonate?

Citric acid and sodium bicarbonate is an antacid that neutralizes stomach acid.

Citric acid and sodium bicarbonate is used to relieve heartburn, indigestion, sour stomach, and upset stomach symptoms.

Citric acid and sodium bicarbonate may also be used for purposes not listed in this medication guide.

Citric acid and sodium bicarbonate side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Common side effects of citric acid and sodium bicarbonate may include:

• nausea, vomiting.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Related/similar drugs

Warnings

Follow all directions on the label and package. Use exactly as directed. Tell your healthcare provider if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use citric acid and sodium bicarbonate if you are allergic to it.

Tell your doctor if you have or have ever had:

• are on a low salt diet.

citric acid and sodium bicarbonate contains phenylalanine and could be harmful if you have phenylketonuria (PKU).

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

How should I take citric acid and sodium bicarbonate?

Use exactly as directed on the label, or as prescribed by your doctor.

Dissolve 2 effervescent tablets in at least 4 ounces of water. Stir and drink right away. Add more water to the glass, swirl and drink.

Adults and children over 12 should not take more than 8 effervescent tablets per day, and people over 60 should not take more than 4 effervescent tablets daily.

Stop using citric acid and sodium bicarbonate and call your doctor if your symptoms do not improve after taking the maximum dose for 2 weeks.

Ask a doctor before giving this medicine to children below 12 years of age.

Store at room temperature away from moisture, heat, and light. Keep out of the reach of children.

What happens if I miss a dose?

Citric acid and sodium bicarbonate is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking citric acid and sodium bicarbonate?

Ask a doctor or pharmacist before using over-the-counter medicines that may contain ingredients similar to citric acid and sodium bicarbonate.

What other drugs will affect citric acid and sodium bicarbonate?

Other drugs may affect citric acid and sodium bicarbonate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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