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Does Skyrizi cause hair loss?

Medically reviewed by Kristianne Hannemann, PharmD. Last updated on March 31, 2025.

Official answer

by Drugs.com

No, Skyrizi (risankizumab) has not been linked to hair loss in clinical trials. Skyrizi is an injectable medication used for the treatment of plaque psoriasis, psoriatic arthritis, ulcerative colitis, and Crohn’s disease.

Clinical Trial Findings

  • Hair loss was not reported as a side effect in FDA-approved clinical trials for Skyrizi.
  • It is not listed as a known side effect in the official Skyrizi prescribing information.
  • A long-term study analyzing data from 17 clinical trials in patients with plaque psoriasis also did not identify hair loss as a side effect.

What If You Experience Hair Loss?

If you notice hair thinning or hair loss (also called alopecia), speak with your healthcare provider. There are many causes of hair loss, including:

  • Stress
  • Dietary changes
  • Other medications

Your doctor can help you determine what is causing your hair loss and provide recommendations for treating it.

References

Gordon, K. B., et. al. (2022). Long‐term safety of risankizumab from 17 clinical trials in patients with moderate‐to‐severe plaque psoriasis. In: British Journal of Dermatology. Accessed on 06/03/2024 at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9298814/

Skyrizi [package insert]. Revised March 2024. AbbVie Inc. Accessed 06/03/2024 at https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7148c8eb-b39e-e20a-6494-a6df82392858

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