Skip to main content

How long does clobetasol stay in your system?

Medically reviewed by Carmen Pope, BPharm. Last updated on Aug 21, 2023.

Official answer

by Drugs.com

It is unknown how long clobetasol stays in your system because the half-life of the drug is not available through any reference source. Some researchers have found that suppression of cortisol levels is still apparent 96 hours after topical use of this medicine, which implies that clobetasol can stay in your system for long periods of time, possibly for up to a few weeks. Clobetasol is not recommended to be used for more than two consecutive weeks.

References
  • Clobetasol Updated Jan 19, 2021. ASHP. https://www.drugs.com/monograph/clobetasol.html
  • Nakamura RC, Abreu Ld, Duque-Estrada B, Tamler C, Leverone AP. Comparison of nail lacquer clobetasol efficacy at 0.05%, 1% and 8% in nail psoriasis treatment: prospective, controlled and randomized pilot study. An Bras Dermatol. 2012 Mar-Apr;87(2):203-11. doi: 10.1590/s0365-05962012000200003. PMID: 22570023.

Read next

Psoriasis typically appears as a red, dry, and flaky patch of skin, and may be covered with white scales called plaques. It can occur on any area of the body, including hands, feet, elbows, scalp or genitals. Psoriasis can feel itchy, sore, burning and the skin may feel tight, crack or bleed. Frequent itching can lead to thicker areas of plaques. Continue reading

Ilumya works by binding selectively to interleukin-23 (IL-23) which is a naturally occurring cytokine. IL-23 plays a key role in promoting inflammation and regulating other cytokines (such as IL-17) and inflammatory substances, such as TNF-α3-7. By blocking the effects of IL-23, Ilumya helps control the release of IL-17 and TNF-α, which reduces inflammation associated with psoriasis. It also decreases how many inflammatory cells are present within psoriatic lesions, helps prevent plaque formation, and resolves tissue damage. Continue reading

Prednisone first came onto the market over sixty years ago and is still going strong. But did you know that this common drug used for a variety of different conditions also has some pretty serious side effects as well? Continue reading

Related medical questions

Drug information

Related support groups

Medical Disclaimer