Skip to main content

Medications for Facial Wrinkles

Other names: Canthal Lines; Lateral Canthal Lines; Nasolabial Folds; Smile Lines; Wrinkles

Facial wrinkles are creases in the skin of the face.

Drugs used to treat Facial Wrinkles

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Botox Cosmetic 4.9 12 reviews for Botox Cosmetic to treat Facial Wrinkles Rx C N
Generic name:
onabotulinumtoxinA systemic
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Botox 4.7 3 reviews for Botox to treat Facial Wrinkles Rx C N
Generic name:
onabotulinumtoxinA systemic
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
onabotulinumtoxinA 5.2 18 reviews for onabotulinumtoxinA to treat Facial Wrinkles Rx C N
Generic name:
onabotulinumtoxinA systemic
Brand names:
Botox Cosmetic, Botox
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
tazarotene 9.0 2 reviews for tazarotene to treat Facial Wrinkles Rx X N
Generic name:
tazarotene topical
Brand name:
Avage
Drug class:
topical acne agents, topical antipsoriatics
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Dysport 4.2 6 reviews for Dysport to treat Facial Wrinkles Rx C N
Generic name:
abobotulinumtoxinA systemic
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Restylane 1.0 4 reviews for Restylane to treat Facial Wrinkles N U
Generic name:
dermal filler topical
For consumers:
Xeomin 7.3 3 reviews for Xeomin to treat Facial Wrinkles Rx C N
Generic name:
incobotulinumtoxinA systemic
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Radiesse 7.3 3 reviews for Radiesse to treat Facial Wrinkles N U
Generic name:
dermal filler topical
For consumers:
Avage Rate Add review Rx X N
Generic name:
tazarotene topical
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Juvederm 4.5 12 reviews for Juvederm to treat Facial Wrinkles Rx N
Generic name:
hyaluronan / lidocaine systemic
For consumers:
interactions,
azficel-t Rate Add review Rx C U
Generic name:
azficel-t systemic
Brand name:
LaViv
For consumers:
abobotulinumtoxinA 4.2 6 reviews for abobotulinumtoxinA to treat Facial Wrinkles Rx C N
Generic name:
abobotulinumtoxinA systemic
Brand name:
Dysport
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
incobotulinumtoxinA 7.3 3 reviews for incobotulinumtoxinA to treat Facial Wrinkles Rx C N
Generic name:
incobotulinumtoxinA systemic
Brand name:
Xeomin
Drug class:
skeletal muscle relaxants
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
LaViv Rate Add review Rx C U
Generic name:
azficel-t systemic
For consumers:
Perlane Rate Add review N U
Generic name:
dermal filler topical
For consumers:
Captique Rate Add review N U
Generic name:
dermal filler topical
For consumers:
Hylaform Plus Rate Add review N U
Generic name:
dermal filler topical
For consumers:
Bellafill 2.9 46 reviews for Bellafill to treat Facial Wrinkles N U
Generic name:
dermal filler topical
For consumers:

Frequently asked questions

View more FAQ

Topics under Facial Wrinkles

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.