Sofosbuvir Interactions
There are 82 drugs known to interact with sofosbuvir, along with 3 disease interactions. Of the total drug interactions, 16 are major, 65 are moderate, and 1 is minor.
- View all 82 medications that may interact with sofosbuvir
- View sofosbuvir disease interactions (3)
Most frequently checked interactions
View interaction reports for sofosbuvir and the medicines listed below.
- Abilify (aripiprazole)
- Acetylsalicylic Acid (aspirin)
- Activated Charcoal (charcoal)
- Adacel (Tdap) (diphtheria toxoid / pertussis, acellular / tetanus toxoid)
- Allegra (fexofenadine)
- Aloprim (allopurinol)
- Anoro Ellipta (umeclidinium / vilanterol)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Atarax (hydroxyzine)
- Augmentin (amoxicillin / clavulanate)
- Azithromycin Dose Pack (azithromycin)
- Calcium 600 D (calcium / vitamin d)
- Chlorpheniramine (Allergy) (chlorpheniramine)
- Heparin Sodium (heparin)
- Lantus (insulin glargine)
- Nexium (esomeprazole)
- Nicotinamide ZCF (multivitamin with minerals)
- Paracetamol (acetaminophen)
- Pegasys (peginterferon alfa-2a)
- PegIntron (peginterferon alfa-2b)
- Retinol (vitamin a topical)
- Rutin (bioflavonoids)
- Sotalol Hydrochloride AF (sotalol)
- Valproate Sodium (valproic acid)
- Vitamin B1 (thiamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- Vitamin D3 (cholecalciferol)
- Vitamin K (phytonadione)
Sofosbuvir disease interactions
There are 3 disease interactions with sofosbuvir which include:
Report options
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More about sofosbuvir
- sofosbuvir consumer information
- Compare alternatives
- Reviews (51)
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antivirals
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
