Drug Interactions between Lexiscan and nicotine
This report displays the potential drug interactions for the following 2 drugs:
- Lexiscan (regadenoson)
- nicotine
Interactions between your drugs
No interactions were found between Lexiscan and nicotine. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Lexiscan
A total of 6 drugs are known to interact with Lexiscan.
- Lexiscan is in the drug class cardiac stressing agents.
- Lexiscan is used to treat the following conditions:
nicotine
A total of 31 drugs are known to interact with nicotine.
- Nicotine is in the drug class smoking cessation agents.
- Nicotine is used to treat Smoking Cessation.
Drug and food interactions
regadenoson food
Applies to: Lexiscan (regadenoson)
ADJUST DOSING INTERVAL: Caffeine and other xanthine derivatives are nonspecific, competitive antagonists of adenosine receptors. As such, they may interfere with the vasodilating effect of regadenoson, an adenosine receptor agonist. In a placebo-controlled study that assessed the effects of oral caffeine on regadenoson-induced increase in coronary flow reserve (CFR), healthy subjects who took caffeine 200 mg orally two hours prior to regadenoson administration exhibited a median CFR that was 92% that of subjects who took placebo. The study was done using positron emission tomography with radiolabeled water.
MANAGEMENT: Patients should avoid consumption of caffeine-containing products for at least 12 hours prior to administration of regadenoson for myocardial perfusion imaging.
References
- (2008) "Product Information. Lexiscan (regadenoson)." Astellas Pharma US, Inc
nicotine food
Applies to: nicotine
One study (n=12) has reported that there was a significant interactive effect of caffeine and nicotine on subjective arousal such that nicotine decreased arousal only in the presence of caffeine. The exact mechanism of this interaction has not been specified. Further research is needed to examine the subjective and physiological interactions between caffeine and nicotine.
References
- Rose JE, Behm FM (1991) "Psychophysiological interactions between caffeine and nicotine." Pharmacol Biochem Behav, 38, p. 333-7
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.