Comparing Trazodone vs Venlafaxine
Trazodone | Venlafaxine |
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Trazodone | Venlafaxine |
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Prescription only
Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Prescription only
Venlafaxine is an antidepressant that may also be used for mood disorders and off-label for some other conditions such as hot flashes. It may cause a discontinuation syndrome if abruptly stopped... View more |
Related suggestions Depression
Major Depressive Disorder
Fibromyalgia
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More about Trazodone | More about Venlafaxine | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Trazodone has an average rating of 6.3 out of 10 from a total of 1404 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 31% reported a negative effect. |
Venlafaxine has an average rating of 6.4 out of 10 from a total of 2752 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 28% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: trazodone side effects in more detail. |
See also: venlafaxine side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all trazodone prices |
View all venlafaxine prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
N/A |
Effexor, Effexor XR | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
7.5 hours |
4 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 648 drugs are known to interact with trazodone:
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A total of 685 drugs are known to interact with venlafaxine:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 24, 1981 |
December 28, 1993 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.