Provigil Alternatives Compared
| Provigil (modafinil) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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| Provigil (modafinil) | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | Adderall (amphetamine / dextroamphetamine) |
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Prescription only
Prescribed for Shift Work Sleep Disorder, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome. Provigil may also be used for purposes not listed in this medication guide. |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Prescription only
Adderall is a combination of four different amphetamine salts and may be used to improve attention, focus, or reduce impulsive behaviors in children over the age of 3 and adults with ADHD. It can... View more |
Related suggestions |
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| More about Provigil (modafinil) | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | More about Adderall (amphetamine / dextroamphetamine) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Provigil has an average rating of 7.4 out of 10 from a total of 169 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 16% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
Adderall has an average rating of 7.2 out of 10 from a total of 505 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Provigil side effects |
View all Xywav side effects |
View all Adderall side effects |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Provigil prices |
View all Xywav prices |
View all Adderall prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
N/A |
Other amphetamine / dextroamphetamine brands include: Adderall XR, Mydayis | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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15 hours |
0.66 hours |
14 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 519 drugs are known to interact with Provigil:
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A total of 346 drugs are known to interact with Xywav:
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A total of 220 drugs are known to interact with Adderall:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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December 24, 1998 |
July 21, 2020 |
January 19, 1960 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.