Comparing Provigil vs Vyvanse
| Provigil (modafinil) | Vyvanse (lisdexamfetamine) |
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| Provigil (modafinil) | Vyvanse (lisdexamfetamine) |
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Prescription only
Prescribed for Shift Work Sleep Disorder, Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome. Provigil may also be used for purposes not listed in this medication guide. |
Prescription only
Vyvanse is a stimulant used for the treatment of ADHD to reduce symptoms such as impulsiveness and hyperactivity and to increase attention. It can also help increase the number of binge-free days per... View more |
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| More about Provigil (modafinil) | More about Vyvanse (lisdexamfetamine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Provigil has an average rating of 7.4 out of 10 from a total of 169 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 16% reported a negative effect. |
Vyvanse has an average rating of 7.4 out of 10 from a total of 973 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Provigil side effects |
View all Vyvanse side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Provigil prices |
View all Vyvanse prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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15 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 519 drugs are known to interact with Provigil:
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A total of 393 drugs are known to interact with Vyvanse:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 24, 1998 |
February 23, 2007 |
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| WADA Class View classifications | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.